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Volumn 31, Issue 15, 2015, Pages 2514-2522

Computational modeling of the expansion of human cord blood CD133+ hematopoietic stem/progenitor cells with different cytokine combinations

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CYTOKINE;

EID: 84943608512     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btv172     Document Type: Article
Times cited : (32)

References (55)
  • 1
    • 79953107633 scopus 로고    scopus 로고
    • Influence of infused cell dose and HLA match on engraftment after double-unit cord blood allografts
    • Avery, S. et al. (2011) Influence of infused cell dose and HLA match on engraftment after double-unit cord blood allografts. Blood, 117, 3277-3285.
    • (2011) Blood , vol.117 , pp. 3277-3285
    • Avery, S.1
  • 2
    • 84885934963 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation: The first 25 years and beyond
    • Ballen, K. K. et al. (2013) Umbilical cord blood transplantation: the first 25 years and beyond. Blood, 122, 491-498.
    • (2013) Blood , vol.122 , pp. 491-498
    • Ballen, K.K.1
  • 3
    • 84897904676 scopus 로고    scopus 로고
    • Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors
    • Benveniste, P. et al. (2014) Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors. Blood, 123, 1167-1177.
    • (2014) Blood , vol.123 , pp. 1167-1177
    • Benveniste, P.1
  • 4
    • 77956519710 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
    • Boitano, A. E. et al. (2010) Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science, 329, 1345-1348.
    • (2010) Science , vol.329 , pp. 1345-1348
    • Boitano, A.E.1
  • 5
    • 0038079749 scopus 로고    scopus 로고
    • Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes
    • Camporeale, A. et al. (2003) Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes. Cancer Res., 63, 3688-3694.
    • (2003) Cancer Res. , vol.63 , pp. 3688-3694
    • Camporeale, A.1
  • 6
    • 84863738908 scopus 로고    scopus 로고
    • A modeling framework for immune-related diseases
    • Castiglione, F. et al. (2012) A modeling framework for immune-related diseases. Math. Model. Nat. Phenom., 7, 40-48.
    • (2012) Math. Model. Nat. Phenom. , vol.7 , pp. 40-48
    • Castiglione, F.1
  • 7
    • 84902206817 scopus 로고    scopus 로고
    • Epigenetic reprogramming induces the expansion of cord blood stem cells
    • Chaurasia, P. et al. (2014) Epigenetic reprogramming induces the expansion of cord blood stem cells. J. Clin. Invest., 124, 2378-2395.
    • (2014) J. Clin. Invest. , vol.124 , pp. 2378-2395
    • Chaurasia, P.1
  • 8
    • 84859853646 scopus 로고    scopus 로고
    • Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation
    • Cheung, A. M. et al. (2012) Distinct but phenotypically heterogeneous human cell populations produce rapid recovery of platelets and neutrophils after transplantation. Blood, 119, 3431-3439.
    • (2012) Blood , vol.119 , pp. 3431-3439
    • Cheung, A.M.1
  • 9
    • 84888212251 scopus 로고    scopus 로고
    • Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice
    • Cheung, A. M. et al. (2013) Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice. Blood, 122, 3129-3137.
    • (2013) Blood , vol.122 , pp. 3129-3137
    • Cheung, A.M.1
  • 10
    • 84901342913 scopus 로고    scopus 로고
    • Agent-based modeling of the immune system: NetLogo, a promising framework
    • 2014
    • Chiacchio, F. et al. (2014) Agent-based modeling of the immune system: NetLogo, a promising framework. Biomed. Res. Int., 2014, article id 907171.
    • (2014) Biomed. Res. Int.
    • Chiacchio, F.1
  • 11
    • 84863011896 scopus 로고    scopus 로고
    • Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
    • Csaszar, E. et al. (2012) Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell, 10, 218-229.
    • (2012) Cell Stem Cell , vol.10 , pp. 218-229
    • Csaszar, E.1
  • 12
    • 84899646174 scopus 로고    scopus 로고
    • Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures
    • Csaszar, E. et al. (2014) Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures. Biotechnol. Bioeng., 111, 1258-1264.
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 1258-1264
    • Csaszar, E.1
  • 13
    • 84921522288 scopus 로고    scopus 로고
    • Enhanced generation of cord blood hematopoietic stem and progenitor cells by culture with StemRegenin1 and Delta1 (Ext-IgG.)
    • Dahlberg, A. et al. (2014) Enhanced generation of cord blood hematopoietic stem and progenitor cells by culture with StemRegenin1 and Delta1 (Ext-IgG.). Leukemia, 28, 2097-2101.
    • (2014) Leukemia , vol.28 , pp. 2097-2101
    • Dahlberg, A.1
  • 14
    • 84895509942 scopus 로고    scopus 로고
    • Improving engraftment and immune reconstitution in umbilical cord blood transplantation
    • Danby, R. and Rocha, V. (2014) Improving engraftment and immune reconstitution in umbilical cord blood transplantation. Front. Immunol., 5, 1-19.
    • (2014) Front. Immunol. , vol.5 , pp. 1-19
    • Danby, R.1    Rocha, V.2
  • 15
    • 24144444671 scopus 로고    scopus 로고
    • Ex vivo expansion of megakaryocyte progenitor cells: Cord blood versus mobilized peripheral blood
    • De Bruyn, C. et al. (2005) Ex vivo expansion of megakaryocyte progenitor cells: cord blood versus mobilized peripheral blood. Stem Cells Dev., 14, 415-424.
    • (2005) Stem Cells Dev. , vol.14 , pp. 415-424
    • De Bruyn, C.1
  • 16
    • 0037322190 scopus 로고    scopus 로고
    • In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1
    • De Haan, G. (2003) In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1. Development, 4, 241-251.
    • (2003) Development , vol.4 , pp. 241-251
    • De Haan, G.1
  • 17
    • 84871891282 scopus 로고    scopus 로고
    • Cord blood graft engineering
    • Delaney, C. et al. (2013) Cord blood graft engineering. Biol. Blood Marrow Transplant., 19(1 Suppl.), S74-S78.
    • (2013) Biol. Blood Marrow Transplant. , vol.19 , Issue.1 , pp. S74-S78
    • Delaney, C.1
  • 18
    • 79955723192 scopus 로고    scopus 로고
    • Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rc-/-(NSG) mice
    • Drake, A. C. et al. (2011) Human CD34+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID Il2rc-/-(NSG) mice. PLoS One, 6, e18382.
    • (2011) PLoS One , vol.6 , pp. e18382
    • Drake, A.C.1
  • 19
    • 0034071346 scopus 로고    scopus 로고
    • Basic fibroblast growth factor positively regulates hematopoietic development
    • Faloon, P. et al. (2000) Basic fibroblast growth factor positively regulates hematopoietic development. Development, 127, 1931-1941.
    • (2000) Development , vol.127 , pp. 1931-1941
    • Faloon, P.1
  • 20
    • 84907221142 scopus 로고    scopus 로고
    • Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
    • Fares, I. et al. (2014) Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal. Science, 345, 1509-1512.
    • (2014) Science , vol.345 , pp. 1509-1512
    • Fares, I.1
  • 21
    • 84908019053 scopus 로고    scopus 로고
    • The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function
    • Fonseca-Pereira, D. et al. (2014) The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function. Nature, 514, 98-101.
    • (2014) Nature , vol.514 , pp. 98-101
    • Fonseca-Pereira, D.1
  • 22
    • 84873622868 scopus 로고    scopus 로고
    • Alternative transplant donor sources: Is there any consensus? Curr
    • Fuchs, E. et al. (2013) Alternative transplant donor sources: is there any consensus? Curr. Opin. Oncol., 25, 173-179.
    • (2013) Opin. Oncol. , vol.25 , pp. 173-179
    • Fuchs, E.1
  • 23
    • 79953050420 scopus 로고    scopus 로고
    • Systems biology in immunology: A computational modeling perspective
    • Germain, R. N. et al. (2011) Systems biology in immunology: a computational modeling perspective. Annu. Rev. Immunol., 29, 527-585.
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 527-585
    • Germain, R.N.1
  • 24
    • 84878532331 scopus 로고    scopus 로고
    • Revision of the human hematopoietic tree: Granulocyte subtypes derive from distinct hematopoietic lineages
    • Goergens, A. et al. (2013) Revision of the human hematopoietic tree: granulocyte subtypes derive from distinct hematopoietic lineages. Cell Rep., 3, 1539-1552.
    • (2013) Cell Rep. , vol.3 , pp. 1539-1552
    • Goergens, A.1
  • 25
    • 84906686932 scopus 로고    scopus 로고
    • Engraftment and lineage potential of adult hematopoietic stem and progenitor cells is compromised following short-term culture in the presence of an aryl hydrocarbon receptor antagonist
    • Gu, A. et al. (2014) Engraftment and lineage potential of adult hematopoietic stem and progenitor cells is compromised following short-term culture in the presence of an aryl hydrocarbon receptor antagonist. Hum. Gene Ther. Methods, 25, 221-231.
    • (2014) Hum. Gene Ther. Methods , vol.25 , pp. 221-231
    • Gu, A.1
  • 26
    • 85023616262 scopus 로고    scopus 로고
    • Getting more for your marrow: Boosting hematopoietic stem cell numbers with PGE2
    • Hagedorn, E. J. et al. (2014) Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. Exp. Cell Res., 4827, 321-328.
    • (2014) Exp. Cell Res. , vol.4827 , pp. 321-328
    • Hagedorn, E.J.1
  • 27
    • 0030752779 scopus 로고    scopus 로고
    • Increased recruitment of hematopoietic progenitor cells underlies the ex vivo expansion potential of FLT3 ligand
    • Haylock, D. N. et al. (1997) Increased recruitment of hematopoietic progenitor cells underlies the ex vivo expansion potential of FLT3 ligand. Blood, 90, 2260-2272.
    • (1997) Blood , vol.90 , pp. 2260-2272
    • Haylock, D.N.1
  • 28
    • 84903794165 scopus 로고    scopus 로고
    • Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment
    • Horwitz, M. E. et al. (2014) Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment. J. Clin. Invest., 124, 3121-3128.
    • (2014) J. Clin. Invest. , vol.124 , pp. 3121-3128
    • Horwitz, M.E.1
  • 29
    • 84898739395 scopus 로고    scopus 로고
    • Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study
    • Kim, S. et al. (2014) Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. Cell Stem Cell, 14, 473-485.
    • (2014) Cell Stem Cell , vol.14 , pp. 473-485
    • Kim, S.1
  • 30
    • 0029903988 scopus 로고    scopus 로고
    • Flt-3 ligand is more potent than c-kit ligand for the synergistic stimulation of ex vivo hematopoietic cell expansion
    • Koller, M. R. et al. (1996) Flt-3 ligand is more potent than c-kit ligand for the synergistic stimulation of ex vivo hematopoietic cell expansion. J. Hematother., 5, 449-459.
    • (1996) J. Hematother. , vol.5 , pp. 449-459
    • Koller, M.R.1
  • 31
    • 53049110682 scopus 로고    scopus 로고
    • MIFlowCyt: The minimum information about a flow cytometry experiment
    • Lee, J. A. et al. (2008) MIFlowCyt: the minimum information about a flow cytometry experiment. Cytometry A, 73, 926-930.
    • (2008) Cytometry A , vol.73 , pp. 926-930
    • Lee, J.A.1
  • 32
    • 34247206624 scopus 로고    scopus 로고
    • CD34 + progenitors are reproducibly recovered in thawed umbilical grafts, and positively influence haematopoietic reconstitution after transplantation
    • Lemarie, C. et al. (2007) CD34 + progenitors are reproducibly recovered in thawed umbilical grafts, and positively influence haematopoietic reconstitution after transplantation. Bone Marrow Transplant., 39, 453-460.
    • (2007) Bone Marrow Transplant. , vol.39 , pp. 453-460
    • Lemarie, C.1
  • 33
    • 84905756677 scopus 로고    scopus 로고
    • Hematopoietic stem cell niche maintenance during homeostasis and regeneration
    • Mendelson, A. and Frenette, P. S. (2014) Hematopoietic stem cell niche maintenance during homeostasis and regeneration. Nat. Med., 20, 833-846.
    • (2014) Nat. Med. , vol.20 , pp. 833-846
    • Mendelson, A.1    Frenette, P.S.2
  • 34
    • 0034667625 scopus 로고    scopus 로고
    • Cell dose and speed of engraftment in placental/umbilical cord blood transplantation: Graft progenitor cell content is a better predictor than nucleated cell quantity
    • Migliaccio, A. R. et al. (2000) Cell dose and speed of engraftment in placental/umbilical cord blood transplantation: graft progenitor cell content is a better predictor than nucleated cell quantity. Blood, 96, 2717-2722.
    • (2000) Blood , vol.96 , pp. 2717-2722
    • Migliaccio, A.R.1
  • 35
    • 84892610064 scopus 로고    scopus 로고
    • The bone marrow niche for haematopoietic stem cells
    • Morrison, S. J. and Scadden, D. T. (2014) The bone marrow niche for haematopoietic stem cells. Nature, 505, 27-334.
    • (2014) Nature , vol.505 , pp. 27-334
    • Morrison, S.J.1    Scadden, D.T.2
  • 36
    • 0030905059 scopus 로고    scopus 로고
    • Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand
    • Ohmizono, Y. et al. (1997) Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand. Leukemia, 11, 524-530.
    • (1997) Leukemia , vol.11 , pp. 524-530
    • Ohmizono, Y.1
  • 37
    • 55049110732 scopus 로고    scopus 로고
    • Oncostatin M-mediated regulation of KIT-ligand-induced extracellular signal-regulated kinase signaling maintains hematopoietic repopulating activity of Lin-CD34+CD133+ cord blood cells
    • Oostendorp, R. A. et al. (2008) Oncostatin M-mediated regulation of KIT-ligand-induced extracellular signal-regulated kinase signaling maintains hematopoietic repopulating activity of Lin-CD34+CD133+ cord blood cells. Stem Cells, 26, 2164-2172.
    • (2008) Stem Cells , vol.26 , pp. 2164-2172
    • Oostendorp, R.A.1
  • 38
    • 79960106880 scopus 로고    scopus 로고
    • Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment
    • Notta, F. et al. (2011) Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science 333, 218-221.
    • (2011) Science , vol.333 , pp. 218-221
    • Notta, F.1
  • 39
    • 80051673064 scopus 로고    scopus 로고
    • Total colony forming units are a strong, independent predictor of neutrophil and platelet engraftment after unrelated umbilical cord blood transplantation: A single-center analysis of 435 cord blood transplants
    • Page, K. M. et al. (2011) Total colony forming units are a strong, independent predictor of neutrophil and platelet engraftment after unrelated umbilical cord blood transplantation: a single-center analysis of 435 cord blood transplants. Biol. Blood Marrow Transplant., 17, 1362-1374.
    • (2011) Biol. Blood Marrow Transplant. , vol.17 , pp. 1362-1374
    • Page, K.M.1
  • 40
    • 84903737191 scopus 로고    scopus 로고
    • Induction of T-cell memory by a dendritic cell vaccine: A computational model
    • Pappalardo, F. et al. (2014b) Induction of T-cell memory by a dendritic cell vaccine: a computational model. Bioinformatics, 30, 1884-1891.
    • (2014) Bioinformatics , vol.30 , pp. 1884-1891
    • Pappalardo, F.1
  • 41
    • 84923314264 scopus 로고    scopus 로고
    • Computational modelling approaches to vaccinology
    • Pappalardo, F. et al. (2015) Computational modelling approaches to vaccinology. Pharmacol. Res., 92, 40-45.
    • (2015) Pharmacol. Res. , vol.92 , pp. 40-45
    • Pappalardo, F.1
  • 42
    • 84878465897 scopus 로고    scopus 로고
    • A novel application for a 3D timelapse assay that distinguishes chemotactic from chemokinetic responses of hematopoietic CD133 (+) stem/progenitor cells
    • Pepperell, E. E. and Watt, S. M. (2013) A novel application for a 3D timelapse assay that distinguishes chemotactic from chemokinetic responses of hematopoietic CD133 (+) stem/progenitor cells. Stem Cell Res., 11, 707-720.
    • (2013) Stem Cell Res. , vol.11 , pp. 707-720
    • Pepperell, E.E.1    Watt, S.M.2
  • 43
    • 0031000903 scopus 로고    scopus 로고
    • Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood
    • Piacibello, W. et al. (1997) Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood, 89, 2644-2653.
    • (1997) Blood , vol.89 , pp. 2644-2653
    • Piacibello, W.1
  • 44
    • 0032760571 scopus 로고    scopus 로고
    • Gp130-signaling synergizes with FL and TPO for the long-term expansion of cord blood progenitors
    • Rappold, I. et al. (1999) Gp130-signaling synergizes with FL and TPO for the long-term expansion of cord blood progenitors. Leukemia, 13, 2036-2048.
    • (1999) Leukemia , vol.13 , pp. 2036-2048
    • Rappold, I.1
  • 45
    • 77649339493 scopus 로고    scopus 로고
    • Cord blood units with low CD34 + cell viability have a low probability of engraftment after double unit transplantation
    • Scaradavou, A. et al. (2010) Cord blood units with low CD34 + cell viability have a low probability of engraftment after double unit transplantation. Biol. Blood Marrow Transplant., 16, 500-508.
    • (2010) Biol. Blood Marrow Transplant. , vol.16 , pp. 500-508
    • Scaradavou, A.1
  • 46
    • 84873542634 scopus 로고    scopus 로고
    • Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia
    • Scaradavou, A. et al. (2013) Double unit grafts successfully extend the application of umbilical cord blood transplantation in adults with acute leukemia. Blood, 121, 752-758.
    • (2013) Blood , vol.121 , pp. 752-758
    • Scaradavou, A.1
  • 47
    • 0032030339 scopus 로고    scopus 로고
    • FLT3: Receptor and ligand. Biology and potential clinical application
    • Shurin, M. R. et al. (1998) FLT3: receptor and ligand. Biology and potential clinical application. Cytokine Growth Factor Rev., 9, 37-48.
    • (1998) Cytokine Growth Factor Rev. , vol.9 , pp. 37-48
    • Shurin, M.R.1
  • 48
    • 84902074449 scopus 로고    scopus 로고
    • CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells
    • Takahashi, M. et al. (2014) CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells. Leukemia, 28, 1308-1315.
    • (2014) Leukemia , vol.28 , pp. 1308-1315
    • Takahashi, M.1
  • 49
    • 81155148219 scopus 로고    scopus 로고
    • Principal signalling complexes in haematopoiesis: Structural aspects and mimetic discovery
    • Tarasova, A. et al. (2011) Principal signalling complexes in haematopoiesis: structural aspects and mimetic discovery. Cytokine Growth Factor Rev., 22, 231-253.
    • (2011) Cytokine Growth Factor Rev. , vol.22 , pp. 231-253
    • Tarasova, A.1
  • 50
    • 84919782092 scopus 로고    scopus 로고
    • Thrombopoietin treatment of one graft in a double cord blood transplant provides early platelet recovery while contributing to long-term engraftment in NSG mice
    • in press
    • Van Der Garde, M. et al. (2014) Thrombopoietin treatment of one graft in a double cord blood transplant provides early platelet recovery while contributing to long-term engraftment in NSG mice. Stem Cells Dev., in press, doi:10.1089/scd.2014.0294.
    • (2014) Stem Cells Dev.
    • Van Der Garde, M.1
  • 51
    • 0036721158 scopus 로고    scopus 로고
    • Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: Influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival
    • Wagner, J. E. et al. (2002) Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival. Blood, 100, 1611-1618.
    • (2002) Blood , vol.100 , pp. 1611-1618
    • Wagner, J.E.1
  • 52
    • 84919802719 scopus 로고    scopus 로고
    • Umbilical cord blood banking
    • Caplan, M. J. ed., Elsevier Press, Kidlington, UK
    • Watt, S. M. (2014) Umbilical cord blood banking. In: Caplan, M. J. (ed.) Reference Module in Biomedical Sciences. Elsevier Press, Kidlington, UK, article 04238.
    • (2014) Reference Module in Biomedical Sciences
    • Watt, S.M.1
  • 53
    • 84878561357 scopus 로고    scopus 로고
    • CD34 (+) expansion with Delta-1 and HOXB4 promotes rapid engraftment and transfusion independence in a Macaca nemestrina cord blood transplant model
    • Watts, K. L. et al. (2013) CD34 (+) expansion with Delta-1 and HOXB4 promotes rapid engraftment and transfusion independence in a Macaca nemestrina cord blood transplant model. Mol. Ther., 21, 1270-1278.
    • (2013) Mol. Ther. , vol.21 , pp. 1270-1278
    • Watts, K.L.1
  • 54
    • 84898725160 scopus 로고    scopus 로고
    • Clonal tracking of Rhesus Macaque hematopoiesis highlights a distinct lineage origin for natural killer cells
    • Wu, C. et al. (2014) Clonal tracking of Rhesus Macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell, 14, 486-499.
    • (2014) Cell Stem Cell , vol.14 , pp. 486-499
    • Wu, C.1
  • 55
    • 43549113659 scopus 로고    scopus 로고
    • Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation
    • Zhang, C. C. et al. (2008) Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood, 111, 3415-3423.
    • (2008) Blood , vol.111 , pp. 3415-3423
    • Zhang, C.C.1


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