메뉴 건너뛰기




Volumn 514, Issue 7520, 2015, Pages 98-101

The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN RET; BCL2L1 PROTEIN, HUMAN; BCL2L1 PROTEIN, MOUSE; NERVE GROWTH FACTOR; PROTEIN BCL X; RET PROTEIN, HUMAN; RET PROTEIN, MOUSE;

EID: 84908019053     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13498     Document Type: Article
Times cited : (85)

References (34)
  • 1
    • 77649119006 scopus 로고    scopus 로고
    • Awakening dormant haematopoietic stem cells
    • Trumpp, A., Essers, M. & Wilson, A. Awakening dormant haematopoietic stem cells. Nature Rev. Immunol. 10, 201-209 (2010).
    • (2010) Nature Rev. Immunol. , vol.10 , pp. 201-209
    • Trumpp, A.1    Essers, M.2    Wilson, A.3
  • 2
    • 84892610064 scopus 로고    scopus 로고
    • The bone marrow niche for haematopoietic stem cells
    • Morrison, S. J. & Scadden, D. T. The bone marrow niche for haematopoietic stem cells. Nature 505, 327-334 (2014).
    • (2014) Nature , vol.505 , pp. 327-334
    • Morrison, S.J.1    Scadden, D.T.2
  • 3
    • 81855183667 scopus 로고    scopus 로고
    • Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche
    • Yamazaki, S. et al. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell 147, 1146-1158 (2011).
    • (2011) Cell , vol.147 , pp. 1146-1158
    • Yamazaki, S.1
  • 4
    • 39749164920 scopus 로고    scopus 로고
    • Haematopoietic stem cell release is regulated by circadian oscillations
    • Mendez-Ferrer, S., Lucas, D., Battista, M. & Frenette, P. S. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 452, 442-447 (2008).
    • (2008) Nature , vol.452 , pp. 442-447
    • Mendez-Ferrer, S.1    Lucas, D.2    Battista, M.3    Frenette, P.S.4
  • 5
    • 84880301799 scopus 로고    scopus 로고
    • Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration
    • Lucas, D. et al. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nature Med. 19, 695-703 (2013).
    • (2013) Nature Med. , vol.19 , pp. 695-703
    • Lucas, D.1
  • 6
    • 34047158654 scopus 로고    scopus 로고
    • Tyrosine kinase receptor RET is a key regulator of Peyer's Patch organogenesis
    • Veiga-Fernandes, H. et al. Tyrosine kinase receptor RET is a key regulator of Peyer's Patch organogenesis. Nature 446, 547-551 (2007).
    • (2007) Nature , vol.446 , pp. 547-551
    • Veiga-Fernandes, H.1
  • 7
    • 84894574242 scopus 로고    scopus 로고
    • RET revisited: Expanding the oncogenic portfolio
    • Mulligan, L. M. RET revisited: expanding the oncogenic portfolio. Nature Rev. Cancer 14, 173-186 (2014).
    • (2014) Nature Rev. Cancer , vol.14 , pp. 173-186
    • Mulligan, L.M.1
  • 8
    • 84871649026 scopus 로고    scopus 로고
    • RET/GFRα signals are dispensable for thymic T cell development in vivo
    • Almeida, A. R. et al. RET/GFRα signals are dispensable for thymic T cell development in vivo. PLoS ONE 7, e52949 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e52949
    • Almeida, A.R.1
  • 9
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel, M. J., Yilmaz, O. H., Iwashita, T., Terhorst, C. & Morrison, S. J. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121 (2005).
    • (2005) Cell , vol.121 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 10
    • 33745965645 scopus 로고    scopus 로고
    • Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors
    • Kim, I., He, S., Yilmaz, O. H., Kiel, M. J. & Morrison, S. J. Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood 108, 737-744 (2006).
    • (2006) Blood , vol.108 , pp. 737-744
    • Kim, I.1    He, S.2    Yilmaz, O.H.3    Kiel, M.J.4    Morrison, S.J.5
  • 11
    • 84864554059 scopus 로고    scopus 로고
    • Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems
    • Patel, A. et al. Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems. Sci. Signal. 5, ra55 (2012).
    • (2012) Sci. Signal. , vol.5 , pp. ra55
    • Patel, A.1
  • 12
    • 77955879913 scopus 로고    scopus 로고
    • Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: Serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches
    • Winkler, I. G. et al. Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches. Blood 116, 375-385 (2010).
    • (2010) Blood , vol.116 , pp. 375-385
    • Winkler, I.G.1
  • 13
    • 84875000886 scopus 로고    scopus 로고
    • Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
    • Ding, L. & Morrison, S. J. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature 495, 231-235 (2013).
    • (2013) Nature , vol.495 , pp. 231-235
    • Ding, L.1    Morrison, S.J.2
  • 14
    • 0028174023 scopus 로고
    • Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
    • Schuchardt, A., D'Agati, V., Larsson-Blomberg, L., Costantini, F. & Pachnis, V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367, 380-383 (1994).
    • (1994) Nature , vol.367 , pp. 380-383
    • Schuchardt, A.1    D'Agati, V.2    Larsson-Blomberg, L.3    Costantini, F.4    Pachnis, V.5
  • 15
    • 0037332003 scopus 로고    scopus 로고
    • Transgenic mice with hematopoietic and lymphoid specific expression of Cre
    • de Boer, J. et al. Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur. J. Immunol. 33, 314-325 (2003).
    • (2003) Eur. J. Immunol. , vol.33 , pp. 314-325
    • De Boer, J.1
  • 16
    • 34548413178 scopus 로고    scopus 로고
    • Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal
    • McMahon, K. A. et al. Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal. Cell Stem Cell 1, 338-345 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 338-345
    • McMahon, K.A.1
  • 17
    • 34247092922 scopus 로고    scopus 로고
    • Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
    • Mansson, R. et al. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26, 407-419 (2007).
    • (2007) Immunity , vol.26 , pp. 407-419
    • Mansson, R.1
  • 18
    • 0037968549 scopus 로고    scopus 로고
    • Gene expression analysis of purified hematopoietic stem cells and committed progenitors
    • Terskikh, A. V., Miyamoto, T., Chang, C., Diatchenko, L. & Weissman, I. L. Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood 102, 94-101 (2003).
    • (2003) Blood , vol.102 , pp. 94-101
    • Terskikh, A.V.1    Miyamoto, T.2    Chang, C.3    Diatchenko, L.4    Weissman, I.L.5
  • 19
    • 45149123052 scopus 로고    scopus 로고
    • Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
    • Thompson, B. J. et al. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7. J. Exp. Med. 205, 1395-1408 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 1395-1408
    • Thompson, B.J.1
  • 20
    • 33645888404 scopus 로고    scopus 로고
    • CREB transcription factor modulates Bcl2 transcription in response to C5a in HL-60-derived neutrophils
    • Perianayagam, M. C., Madias, N. E., Pereira, B. J. & Jaber, B. L. CREB transcription factor modulates Bcl2 transcription in response to C5a in HL-60-derived neutrophils. Eur. J. Clin. Invest. 36, 353-361 (2006).
    • (2006) Eur. J. Clin. Invest. , vol.36 , pp. 353-361
    • Perianayagam, M.C.1    Madias, N.E.2    Pereira, B.J.3    Jaber, B.L.4
  • 21
    • 73649113789 scopus 로고    scopus 로고
    • Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis
    • Shukla, A. et al. Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis. Am. J. Pathol. 175, 2197-2206 (2009).
    • (2009) Am. J. Pathol. , vol.175 , pp. 2197-2206
    • Shukla, A.1
  • 22
    • 0028175759 scopus 로고
    • Targeted disruption of Bcl-2αβ in mice: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia
    • Nakayama, K., Negishi, I., Kuida, K., Sawa, H. & Loh, D. Y. Targeted disruption of Bcl-2αβ in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc. Natl Acad. Sci. USA 91, 3700-3704 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 3700-3704
    • Nakayama, K.1    Negishi, I.2    Kuida, K.3    Sawa, H.4    Loh, D.Y.5
  • 23
    • 0028922885 scopus 로고
    • Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice
    • Motoyama, N. et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267, 1506-1510 (1995).
    • (1995) Science , vol.267 , pp. 1506-1510
    • Motoyama, N.1
  • 24
    • 0032114122 scopus 로고    scopus 로고
    • GFRα1 is an essential receptor component for GDNF in the developing nervous system and kidney
    • Cacalano, G. et al. GFRα1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron 21, 53-62 (1998).
    • (1998) Neuron , vol.21 , pp. 53-62
    • Cacalano, G.1
  • 25
    • 0033172962 scopus 로고    scopus 로고
    • GFR α3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion
    • Nishino, J. et al. GFR α3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron 23, 725-736 (1999).
    • (1999) Neuron , vol.23 , pp. 725-736
    • Nishino, J.1
  • 26
    • 0033083093 scopus 로고    scopus 로고
    • Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR α2, a functional neurturin receptor
    • Rossi, J. et al. Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR α2, a functional neurturin receptor. Neuron 22, 243-252 (1999).
    • (1999) Neuron , vol.22 , pp. 243-252
    • Rossi, J.1
  • 27
    • 31044450303 scopus 로고    scopus 로고
    • Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow
    • Katayama, Y. et al. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 124, 407-421 (2006).
    • (2006) Cell , vol.124 , pp. 407-421
    • Katayama, Y.1
  • 28
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • Mendez-Ferrer, S. et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466, 829-834 (2010).
    • (2010) Nature , vol.466 , pp. 829-834
    • Mendez-Ferrer, S.1
  • 29
    • 34548777583 scopus 로고    scopus 로고
    • Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling
    • Spiegel, A. et al. Catecholaminergic neurotransmitters regulate migration and repopulation of immature human CD34+ cells through Wnt signaling. Nature Immunol. 8, 1123-1131 (2007).
    • (2007) Nature Immunol. , vol.8 , pp. 1123-1131
    • Spiegel, A.1
  • 30
    • 0026585781 scopus 로고
    • RAG-1-deficient mice have no mature B and T lymphocytes
    • Mombaerts, P. et al. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68, 869-877 (1992).
    • (1992) Cell , vol.68 , pp. 869-877
    • Mombaerts, P.1
  • 31
    • 77951015274 scopus 로고    scopus 로고
    • Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice
    • Uesaka, T. & Enomoto, H. Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice. J. Neurosci. 30, 5211-5218 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 5211-5218
    • Uesaka, T.1    Enomoto, H.2
  • 32
    • 84886947010 scopus 로고    scopus 로고
    • Arteriolar niches maintain haematopoietic stem cell quiescence
    • Kunisaki, Y. et al. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 502, 637-643 (2014).
    • (2014) Nature , vol.502 , pp. 637-643
    • Kunisaki, Y.1
  • 33
    • 84897480560 scopus 로고    scopus 로고
    • Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity
    • van de Pavert, S. A. et al. Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity. Nature 508, 123-127 (2014).
    • (2014) Nature , vol.508 , pp. 123-127
    • Van De Pavert, S.A.1
  • 34
    • 34249032702 scopus 로고    scopus 로고
    • CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response
    • Peixoto, A. et al. CD8 single-cell gene coexpression reveals three different effector types present at distinct phases of the immune response. J. Exp. Med. 204, 1193-1205 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1193-1205
    • Peixoto, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.