메뉴 건너뛰기




Volumn 5, Issue 5, 1996, Pages 449-459

flt-3 ligand is more potent than c-kit ligand for the synergistic stimulation of ex vivo hematopoietic cell expansion

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; ERYTHROPOIETIN; FLT3 LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; PROTEIN TYROSINE KINASE; STEM CELL FACTOR; UNCLASSIFIED DRUG;

EID: 0029903988     PISSN: 15258165     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.1.1996.5.449     Document Type: Article
Times cited : (29)

References (53)
  • 1
    • 0022419320 scopus 로고
    • The granulocyte-macrophage colony-stimulating factors
    • Metcalf, D. The granulocyte-macrophage colony-stimulating factors. Science 229:16, 1985.
    • (1985) Science , vol.229 , pp. 16
    • Metcalf, D.1
  • 2
    • 0025836321 scopus 로고
    • Clinical implications of positive and negative hematopoietic stem cell regulators
    • Moore, M.A.S. Clinical implications of positive and negative hematopoietic stem cell regulators. Blood 78:1, 1991.
    • (1991) Blood , vol.78 , pp. 1
    • Moore, M.A.S.1
  • 3
    • 0027136259 scopus 로고
    • Hematopoietic regulators: Redundancy or subtlety?
    • Metcalf, D. Hematopoietic regulators: Redundancy or subtlety? Blood 82:3515, 1993.
    • (1993) Blood , vol.82 , pp. 3515
    • Metcalf, D.1
  • 4
    • 0028242261 scopus 로고
    • Stem cell factor enhances the survival but not the self-renewal of murine hematopoietic long-term repopulating cells
    • Li, C.L. & Johnson, G.R. Stem cell factor enhances the survival but not the self-renewal of murine hematopoietic long-term repopulating cells. Blood 84:408, 1994.
    • (1994) Blood , vol.84 , pp. 408
    • Li, C.L.1    Johnson, G.R.2
  • 5
    • 0001494471 scopus 로고
    • Hydrocortisone influences hematopoiesis through modulation of the growth factor network in the bone marrow microenvironment
    • abstract
    • Koller, M.R., Maher, R.J. & Palsson, B.Ø. Hydrocortisone influences hematopoiesis through modulation of the growth factor network in the bone marrow microenvironment. Exp. Hematol. 23:768 (abstract), 1995.
    • (1995) Exp. Hematol. , vol.23 , pp. 768
    • Koller, M.R.1    Maher, R.J.2    Palsson, B.Ø.3
  • 6
    • 0025013548 scopus 로고
    • Identification of a ligand for the c-kit proto-oncogene
    • Williams, D.E., Eisenman, J., Baird, A., et al. Identification of a ligand for the c-kit proto-oncogene. Cell 63:167, 1990.
    • (1990) Cell , vol.63 , pp. 167
    • Williams, D.E.1    Eisenman, J.2    Baird, A.3
  • 7
    • 0025001892 scopus 로고
    • Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium
    • Zsebo, K.M., Wypych, J., McNiece, I.K., et al. Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium. Cell 63:195, 1990.
    • (1990) Cell , vol.63 , pp. 195
    • Zsebo, K.M.1    Wypych, J.2    McNiece, I.K.3
  • 8
    • 0025077796 scopus 로고
    • The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus
    • Huang, E., Nocka, K., Beier, D.R., et al. The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 63:225, 1990.
    • (1990) Cell , vol.63 , pp. 225
    • Huang, E.1    Nocka, K.2    Beier, D.R.3
  • 9
    • 0028203747 scopus 로고
    • Cloning of the human homologue of the murine flt-3 ligand: A growth factor for early hematopoietic progenitor cells
    • Lyman, S.D., James, L., Johnson, L., et al. Cloning of the human homologue of the murine flt-3 ligand: A growth factor for early hematopoietic progenitor cells. Blood 83:2795, 1994.
    • (1994) Blood , vol.83 , pp. 2795
    • Lyman, S.D.1    James, L.2    Johnson, L.3
  • 10
    • 0028318788 scopus 로고
    • Ligand for FLT3/FLK2 receptor tyrosine kinase regulates the growth of haematopoietic stem cells and is encoded by variant RNAs
    • Hannum, C., Culpepper, J., Campbell, D., et al. Ligand for FLT3/FLK2 receptor tyrosine kinase regulates the growth of haematopoietic stem cells and is encoded by variant RNAs. Nature 368:643, 1994.
    • (1994) Nature , vol.368 , pp. 643
    • Hannum, C.1    Culpepper, J.2    Campbell, D.3
  • 11
    • 0025898727 scopus 로고
    • Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3, and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages
    • McNiece, I.K., Langley, K.E. & Zsebo, K.M. Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3, and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp. Hematol. 19:226, 1991.
    • (1991) Exp. Hematol. , vol.19 , pp. 226
    • McNiece, I.K.1    Langley, K.E.2    Zsebo, K.M.3
  • 12
    • 0025851421 scopus 로고
    • - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor
    • - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor. Blood 77:2316, 1991.
    • (1991) Blood , vol.77 , pp. 2316
    • Bernstein, I.D.1    Andrews, R.G.2    Zsebo, K.M.3
  • 13
    • 0025779041 scopus 로고
    • Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells
    • Broxmeyer, H.E., Cooper, S., Lu, L., et al. Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells. Blood 77:2142, 1991.
    • (1991) Blood , vol.77 , pp. 2142
    • Broxmeyer, H.E.1    Cooper, S.2    Lu, L.3
  • 14
    • 0026755568 scopus 로고
    • Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture
    • Tsuji, K., Lyman, S.D., Sudo, T., et al. Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood 79:2855, 1992.
    • (1992) Blood , vol.79 , pp. 2855
    • Tsuji, K.1    Lyman, S.D.2    Sudo, T.3
  • 15
    • 0026452859 scopus 로고
    • The ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboon
    • Andrews, R.G., Bensinger, W.I., Knitter, G.H., et al. The ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboon. Blood 80:2715, 1992.
    • (1992) Blood , vol.80 , pp. 2715
    • Andrews, R.G.1    Bensinger, W.I.2    Knitter, G.H.3
  • 16
    • 0027326032 scopus 로고
    • In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells
    • Bodine, D.M., Seidel, N.E., Zsebo, K.M., et al. In vivo administration of stem cell factor to mice increases the absolute number of pluripotent hematopoietic stem cells. Blood 82:445, 1993.
    • (1993) Blood , vol.82 , pp. 445
    • Bodine, D.M.1    Seidel, N.E.2    Zsebo, K.M.3
  • 17
    • 0027304593 scopus 로고
    • In vivo administration of recombinant methionyl human stem cell factor expands the number of human marrow hematopoietic stem cells
    • Tong, J., Gordon, M.S., Srour, E.F., et al. In vivo administration of recombinant methionyl human stem cell factor expands the number of human marrow hematopoietic stem cells. Blood 82:784, 1993.
    • (1993) Blood , vol.82 , pp. 784
    • Tong, J.1    Gordon, M.S.2    Srour, E.F.3
  • 18
    • 0029042188 scopus 로고
    • Stem cell factor retards differentiation of normal human erythroid progenitor cells while stimulating proliferation
    • Muta, K., Krantz, S.B., Bondurant, M.C., et al. Stem cell factor retards differentiation of normal human erythroid progenitor cells while stimulating proliferation. Blood 86:572, 1995.
    • (1995) Blood , vol.86 , pp. 572
    • Muta, K.1    Krantz, S.B.2    Bondurant, M.C.3
  • 19
    • 0028928832 scopus 로고
    • FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver
    • Muench, M.O., Roncarolo, M.G., Menon, S., et al. FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver. Blood 85:963, 1995.
    • (1995) Blood , vol.85 , pp. 963
    • Muench, M.O.1    Roncarolo, M.G.2    Menon, S.3
  • 20
    • 0028952954 scopus 로고
    • The flt-3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors
    • Hirayama, F., Lyman, S.D., Clark, S.C., et al. The flt-3 ligand supports proliferation of lymphohematopoietic progenitors and early B-lymphoid progenitors. Blood 85:1762, 1995.
    • (1995) Blood , vol.85 , pp. 1762
    • Hirayama, F.1    Lyman, S.D.2    Clark, S.C.3
  • 21
    • 0029006853 scopus 로고
    • FLT3/FLK2 ligand promotes the growth of murine stem cells and the expansion of colony-forming cells and spleen colony-forming units
    • Hudak, S., Hunte, B., Culpepper, J., et al. FLT3/FLK2 ligand promotes the growth of murine stem cells and the expansion of colony-forming cells and spleen colony-forming units. Blood 85:2747, 1995.
    • (1995) Blood , vol.85 , pp. 2747
    • Hudak, S.1    Hunte, B.2    Culpepper, J.3
  • 22
    • 0029134556 scopus 로고
    • Multi-level effects of flt-3 ligand on human hematopoiesis: Expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors
    • Gabbianelli, M., Pelosi, E., Montesoro, E., et al. Multi-level effects of flt-3 ligand on human hematopoiesis: Expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors. Blood 86:1661, 1995.
    • (1995) Blood , vol.86 , pp. 1661
    • Gabbianelli, M.1    Pelosi, E.2    Montesoro, E.3
  • 23
    • 0029151332 scopus 로고
    • Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells
    • Broxmeyer, H.E., Lu, L., Cooper, S., et al. Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells. Exp. Hematol. 23:1121, 1995.
    • (1995) Exp. Hematol. , vol.23 , pp. 1121
    • Broxmeyer, H.E.1    Lu, L.2    Cooper, S.3
  • 26
    • 0027286640 scopus 로고
    • + progenitor cells by stem cell factor, interleukin-1β (IL-1β), IL-6, IL-3, interferon-γ, and erythropoietin
    • + progenitor cells by stem cell factor, interleukin-1β (IL-1β), IL-6, IL-3, interferon-γ, and erythropoietin. Blood 81:2579, 1993.
    • (1993) Blood , vol.81 , pp. 2579
    • Brugger, W.1    Möcklin, W.2    Heimfeld, S.3
  • 27
    • 0027162426 scopus 로고
    • Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion culture
    • Koller, M.R., Emerson, S.G. & Palsson, B.Ø. Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion culture. Blood 82:378, 1993.
    • (1993) Blood , vol.82 , pp. 378
    • Koller, M.R.1    Emerson, S.G.2    Palsson, B.Ø.3
  • 28
    • 0029131059 scopus 로고
    • LTC-IC expansion is dependent on frequent medium exchange combined with stromal and other accessory cell effects
    • Koller, M.R., Palsson, M.A., Manchel, I., et al. LTC-IC expansion is dependent on frequent medium exchange combined with stromal and other accessory cell effects. Blood 86:1784, 1995.
    • (1995) Blood , vol.86 , pp. 1784
    • Koller, M.R.1    Palsson, M.A.2    Manchel, I.3
  • 29
    • 0028037626 scopus 로고
    • Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells
    • Zandstra, P.W., Eaves, C.J. & Piret, J.M. Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells. Biotechnology 12:909, 1994.
    • (1994) Biotechnology , vol.12 , pp. 909
    • Zandstra, P.W.1    Eaves, C.J.2    Piret, J.M.3
  • 30
    • 0029113661 scopus 로고
    • + cell selection and perfusion on ex vivo expansion of peripheral blood mononuclear cells
    • + cell selection and perfusion on ex vivo expansion of peripheral blood mononuclear cells. Blood 86:958, 1995.
    • (1995) Blood , vol.86 , pp. 958
    • Sandstrom, C.E.1    Bender, J.G.2    Papoutsakis, E.T.3
  • 31
    • 0028859214 scopus 로고
    • Multilineal hematopoiesis in a three-dimensional murine long-term bone marrow culture
    • Wang, T.-Y., Brennan, J.K. & Wu, J.H.D. Multilineal hematopoiesis in a three-dimensional murine long-term bone marrow culture. Exp. Hematol. 23:26, 1995.
    • (1995) Exp. Hematol. , vol.23 , pp. 26
    • Wang, T.-Y.1    Brennan, J.K.2    Wu, J.H.D.3
  • 32
    • 0028820455 scopus 로고
    • Bioreactor expansion of human bone marrow: Comparison of unprocessed, density-separated, and CD34-enriched cells
    • Koller, M.R., Manchel, I., Newsom, B.S., et al. Bioreactor expansion of human bone marrow: Comparison of unprocessed, density-separated, and CD34-enriched cells. J. Hematother. 4:159, 1995.
    • (1995) J. Hematother. , vol.4 , pp. 159
    • Koller, M.R.1    Manchel, I.2    Newsom, B.S.3
  • 33
    • 0028841516 scopus 로고
    • Growth factor consumption and production in perfusion cultures of human bone marrow correlates with specific cell production
    • Koller, M.R., Bradley, M.S. & Palsson, B.Ø. Growth factor consumption and production in perfusion cultures of human bone marrow correlates with specific cell production. Exp. Hematol. 23:1275, 1995.
    • (1995) Exp. Hematol. , vol.23 , pp. 1275
    • Koller, M.R.1    Bradley, M.S.2    Palsson, B.Ø.3
  • 34
    • 0026316479 scopus 로고
    • In vitro myelopoiesis stimulated by rapid medium exchange and supplementation with hematopoietic growth factors
    • Schwartz, R.M., Emerson, S.G., Clarke, M.F., et al. In vitro myelopoiesis stimulated by rapid medium exchange and supplementation with hematopoietic growth factors. Blood 78:3155, 1991.
    • (1991) Blood , vol.78 , pp. 3155
    • Schwartz, R.M.1    Emerson, S.G.2    Clarke, M.F.3
  • 35
    • 0026053037 scopus 로고
    • Rapid medium perfusion rate significantly increases the productivity and longevity of human bone marrow cultures
    • Schwartz, R.M., Palsson, B.Ø. & Emerson, S.G. Rapid medium perfusion rate significantly increases the productivity and longevity of human bone marrow cultures. Proc. Natl. Acad. Sci. USA 88:6760, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6760
    • Schwartz, R.M.1    Palsson, B.Ø.2    Emerson, S.G.3
  • 36
    • 0030570265 scopus 로고    scopus 로고
    • Different measures of ex vivo human hematopoietic culture performance are optimized under vastly different conditions
    • Koller, M.R., Manchel, I., Palsson, M.A., et al. Different measures of ex vivo human hematopoietic culture performance are optimized under vastly different conditions. Biotechnol. Bioeng. 50:505, 1996.
    • (1996) Biotechnol. Bioeng. , vol.50 , pp. 505
    • Koller, M.R.1    Manchel, I.2    Palsson, M.A.3
  • 37
    • 0020067009 scopus 로고
    • The evaluation of limiting dilution assays
    • de St. Groth, S.F. The evaluation of limiting dilution assays. J. Immunol. Methods 49:R11, 1982.
    • (1982) J. Immunol. Methods , vol.49
    • De St. Groth, S.F.1
  • 38
    • 0344435497 scopus 로고
    • The estimation of bacterial densities from dilution series
    • Finney, D.J. The estimation of bacterial densities from dilution series. J. Hyg. 49:26, 1951.
    • (1951) J. Hyg. , vol.49 , pp. 26
    • Finney, D.J.1
  • 39
    • 0029907055 scopus 로고    scopus 로고
    • Donor-to-donor variability in the expansion potential of human bone marrow cells is reduced by accessory cells but not by soluble growth factors
    • In press
    • Koller, M.R., Manchel, I., Brott, D.A., et al. Donor-to-donor variability in the expansion potential of human bone marrow cells is reduced by accessory cells but not by soluble growth factors. Exp. Hematol. 1996. In press.
    • (1996) Exp. Hematol.
    • Koller, M.R.1    Manchel, I.2    Brott, D.A.3
  • 40
    • 0027652262 scopus 로고
    • Tissue engineering: Reconstitution of human hematopoiesis ex vivo
    • Koller, M.R. & Palsson, B.Ø. Tissue engineering: Reconstitution of human hematopoiesis ex vivo. Biotechnol. Bioeng. 42:909, 1993.
    • (1993) Biotechnol. Bioeng. , vol.42 , pp. 909
    • Koller, M.R.1    Palsson, B.Ø.2
  • 42
    • 0027510014 scopus 로고
    • Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: An effect enhanced by cord blood plasma
    • Carow, C.E., Hangoc, G. & Broxmeyer, H.E. Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: An effect enhanced by cord blood plasma. Blood 81:365, 1993.
    • (1993) Blood , vol.81 , pp. 365
    • Carow, C.E.1    Hangoc, G.2    Broxmeyer, H.E.3
  • 43
    • 0028483121 scopus 로고
    • Frequent harvesting from perfused human bone marrow cultures results in increased cumulative cell and CFU-GM expansion
    • Oh, D.-J., Koller, M.R. & Palsson, B.Ø. Frequent harvesting from perfused human bone marrow cultures results in increased cumulative cell and CFU-GM expansion. Biotechnol. Bioeng. 44:609, 1994.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 609
    • Oh, D.-J.1    Koller, M.R.2    Palsson, B.Ø.3
  • 44
    • 0344418832 scopus 로고    scopus 로고
    • Replating of bioreactor expanded human bone marrow results in extended growth of primitive and mature cells
    • Palsson, B.Ø., Oh, D.-J. & Koller, M.R. Replating of bioreactor expanded human bone marrow results in extended growth of primitive and mature cells. Cytotechnology 18:125, 1996.
    • (1996) Cytotechnology , vol.18 , pp. 125
    • Palsson, B.Ø.1    Oh, D.-J.2    Koller, M.R.3
  • 45
    • 0027470436 scopus 로고
    • +++ human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential
    • +++ human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential. Blood 81:41, 1993.
    • (1993) Blood , vol.81 , pp. 41
    • Lu, L.1    Xiao, M.2    Shen, R.-N.3
  • 46
    • 0027217492 scopus 로고
    • - progenitor cells in long-term cultures and semisolid assays
    • - progenitor cells in long-term cultures and semisolid assays. Blood 81:2916, 1993.
    • (1993) Blood , vol.81 , pp. 2916
    • Issaad, C.1    Croisille, L.2    Katz, A.3
  • 47
    • 0028080987 scopus 로고
    • Cellular and molecular characterization of the role of the FLK-2/FLT-3 receptor tyrosine kinase in hematopoietic stem cells
    • Zeigler, F.C., Bennett, B.D., Jordan, C.T., et al. Cellular and molecular characterization of the role of the FLK-2/FLT-3 receptor tyrosine kinase in hematopoietic stem cells. Blood 84:2422, 1994.
    • (1994) Blood , vol.84 , pp. 2422
    • Zeigler, F.C.1    Bennett, B.D.2    Jordan, C.T.3
  • 48
    • 0027531374 scopus 로고
    • Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: Effect of stromal cells and c-kit
    • Wineman, J.P., Nishikawa, S.-I. & Müller-Sieburg, C.E. Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: Effect of stromal cells and c-kit. Blood 81:365, 1993.
    • (1993) Blood , vol.81 , pp. 365
    • Wineman, J.P.1    Nishikawa, S.-I.2    Müller-Sieburg, C.E.3
  • 49
    • 0027466339 scopus 로고
    • Alternative mechanisms with and without steel factor support primitive human hematopoiesis
    • Sutherland, H.J., Hogge, D.E., Cook, D., et al. Alternative mechanisms with and without steel factor support primitive human hematopoiesis. Blood 81:1465, 1993.
    • (1993) Blood , vol.81 , pp. 1465
    • Sutherland, H.J.1    Hogge, D.E.2    Cook, D.3
  • 50
    • 0021191317 scopus 로고
    • The essential cells of the hemopoietic microenvironment
    • Allen, T.D. & Dexter, T.M. The essential cells of the hemopoietic microenvironment. Exp. Hematol. 12:517, 1984.
    • (1984) Exp. Hematol. , vol.12 , pp. 517
    • Allen, T.D.1    Dexter, T.M.2
  • 51
    • 0019411743 scopus 로고
    • Close range cell:cell interaction required for stem cell maintenance in continuous bone marrow culture
    • Bentley, S.A. Close range cell:cell interaction required for stem cell maintenance in continuous bone marrow culture. Exp. Hematol. 9:308, 1981.
    • (1981) Exp. Hematol. , vol.9 , pp. 308
    • Bentley, S.A.1
  • 52
    • 0025234624 scopus 로고
    • Regulation of hemopoiesis by bone marrow stromal cells and their products
    • Dorshkind, K. Regulation of hemopoiesis by bone marrow stromal cells and their products. Annu. Rev. Immunol. 8:111, 1990.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 111
    • Dorshkind, K.1
  • 53
    • 0029915836 scopus 로고    scopus 로고
    • Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells
    • Gupta, P., McCarthy, J.B. & Verfaillie, C.M. Stromal fibroblast heparan sulfate is required for cytokine-mediated ex vivo maintenance of human long-term culture-initiating cells. Blood 87:3229, 1996.
    • (1996) Blood , vol.87 , pp. 3229
    • Gupta, P.1    McCarthy, J.B.2    Verfaillie, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.