The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway

PLoS Genetics

Volumn 11, Issue 9, 2015, Pages

  Imai, Yuzuru ^a   Kobayashi, Yoshito ^b,c   Inoshita, Tsuyoshi ^a   Meng, Hongrui ^a   Arano, Taku ^a   Uemura, Kengo ^b   Asano, Takeshi ^b   Yoshimi, Kenji ^a   Zhang, Chang Liang ^b,c   Matsumoto, Gen ^a   Ohtsuka, Toshiyuki ^b   Kageyama, Ryoichiro ^b   Kiyonari, Hiroshi ^d   Shioi, Go ^d   Nukina, Nobuyuki ^a   Hattori, Nobutaka ^a,c   Takahashi, Ryosuke ^b,c  

^a JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; LEUCINE RICH REPEAT KINASE 2; NOTCH LIGAND DELTA LIKE 1 PROTEIN; NOTCH RECEPTOR; PROTEIN HERC2; PROTEIN NEURL4; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CARRIER PROTEIN; DOPAMINE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HERC2 PROTEIN, HUMAN; LRRK2 PROTEIN, HUMAN; NEURL4 PROTEIN, HUMAN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DOPAMINERGIC NERVE CELL; EMBRYO; ENDOSOME; ENZYME REGULATION; MOUSE; NEURAL STEM CELL; NONHUMAN; PARKINSON DISEASE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; ANIMAL; DROSOPHILA; ENZYMOLOGY; HEK293 CELL LINE; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; CARRIER PROTEINS; DOPAMINE; DROSOPHILA; ENDOSOMES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HUMANS; LEUCINE-RICH REPEAT SERINE-THREONINE PROTEIN KINASE-2; PARKINSON DISEASE; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84943538985     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005503     Document Type: Article

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