GTPase activity regulates kinase activity and cellular phenotypes of parkinson's disease-associated LRRK2

Human Molecular Genetics

Volumn 22, Issue 6, 2013, Pages 1140-1156

  Biosa, Alice ^a,b   Trancikova, Alzbeta ^a,d   Civiero, Laura ^c   Glauser, Liliane ^a   Bubacco, Luigi ^c   Greggio, Elisa ^c   Moore, Darren J ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY OF SASSARI   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d UCB PHARMA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; LEUCINE RICH REPEAT KINASE 2; MUTANT PROTEIN; PHOSPHOTRANSFERASE; PROTEIN KINASE;

ARTICLE; BRAIN CELL; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVITY; GENE STRUCTURE; GENETIC STABILITY; HUMAN; HUMAN CELL; MISSENSE MUTATION; MOLECULARLY TARGETED THERAPY; NEURITE; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN HYDROLYSIS;

ANIMALS; DIMERIZATION; FEMALE; GTP PHOSPHOHYDROLASES; GUANINE NUCLEOTIDES; GUANOSINE TRIPHOSPHATE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MUTATION, MISSENSE; NEURONS; PARKINSON DISEASE; PHENOTYPE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84874541806     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/dds522     Document Type: Article

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