Evolution in the understanding of the pathophysiological basis of portal hypertension: How changes in paradigm are leading to successful new treatments

Journal of Hepatology

Volumn 62, Issue S1, 2015, Pages S121-S130

  Bosch, Jaume ^a   Groszmann, Roberto J ^b   Shah, Vijay H ^c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Endothelial dysfunction; Hepatic stellate cells; Hyperdynamic syndrome; Liver sinusoidal endothelial cells; Portal pressure; Splanchnic vasodilation

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; MATRIX PROTEIN; SOMATOSTATIN; SOMATOSTATIN DERIVATIVE; VASOPRESSIN DERIVATIVE;

ANGIOGENESIS; DISEASE COURSE; ENDOTHELIUM CELL; ESOPHAGUS VARICES; EXOSOME; HUMAN; LIVER CIRCULATION; LIVER CIRRHOSIS; LIVER SINUSOID; MOLECULAR PATHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; PRIORITY JOURNAL; PROGNOSIS; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SINUSOIDAL ENDOTHELIAL CELL; SPLANCHNIC BLOOD FLOW; STELLATE CELL; SYSTEMIC CIRCULATION; THROMBUS; VASCULAR RESISTANCE; VASODILATATION; VEIN RUPTURE; HEPATIC ARTERY; HYPERTENSION, PORTAL;

HEPATIC ARTERY; HUMANS; HYPERTENSION, PORTAL; LIVER CIRCULATION; NEOVASCULARIZATION, PHYSIOLOGIC; SPLANCHNIC CIRCULATION;

EID: 84943381123     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.01.003     Document Type: Review

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