Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces

Hepatology

Volumn 61, Issue 2, 2015, Pages 648-659

  Simonetto, Douglas A ^a   Yang, Hui yin ^a,b   Yin, Meng ^a   de Assuncao, Thiago M ^a   Kwon, Jung Hee ^a   Hilscher, Moira ^a   Pan, Shuchong ^a   Yang, Liu ^a   Bi, Yan ^a   Beyder, Arthur ^a   Cao, Sheng ^a   Simari, Robert D ^a   Ehman, Richard ^a   Kamath, Patrick S ^a   Shah, Vijay H ^a  

^a MAYO CLINIC   (United States)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTEGRIN; CYTOCHALASIN D; FIBRIN; FIBRONECTIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 13; TISSUE FACTOR PATHWAY INHIBITOR; TRANSGELIN; UNCLASSIFIED DRUG; WARFARIN; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; ANTICOAGULANT AGENT;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; CELL ACTIVATION; CHRONIC PASSIVE HEPATIC CONGESTION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELASTOGRAPHY; EXPERIMENTAL MODEL; FIBRIN DEPOSITION; FIBROGENESIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CONGESTION; LIVER FIBROSIS; MAGNETIC RESONANCE ELASTOGRAPHY; MECHANICAL STRAIN; MECHANICAL STRESS; MORPHOMETRICS; MOUSE; NONHUMAN; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN POLYMERIZATION; REAL TIME POLYMERASE CHAIN REACTION; RIGIDITY; SINUSOIDAL THROMBOSIS; STELLATE CELL; THROMBOSIS; TRANSGENIC MOUSE; WESTERN BLOTTING; ADULT; AGED; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CELL CULTURE; COMPLICATION; DISEASE MODEL; FEMALE; HYPEREMIA; INFERIOR CAVA VEIN; LIGATION; LIVER CIRCULATION; LIVER CIRRHOSIS; MALE; METABOLISM; MIDDLE AGED; YOUNG ADULT;

ACTINS; ADULT; AGED; ANIMALS; ANTICOAGULANTS; CASE-CONTROL STUDIES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; FIBRIN; FIBRONECTINS; HEPATIC STELLATE CELLS; HUMANS; HYPEREMIA; LIGATION; LIVER CIRCULATION; LIVER CIRRHOSIS; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; THROMBOSIS; VENA CAVA, INFERIOR; YOUNG ADULT;

EID: 84921483405     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27387     Document Type: Article

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