The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statins

Journal of Hepatology

Volumn 58, Issue 1, 2013, Pages 98-103

  Marrone, Giusi ^a   Russo, Lucia ^a   Rosado, Eugenio ^a   Hide, Diana ^a   García Cardeña, Guillermo ^b   García Pagán, Juan Carlos ^a   Bosch, Jaime ^a,d   Gracia Sancho, Jorge ^a,c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d HOSPITAL CLÍNIC   (Spain)

Author keywords

Cirrhosis; Endothelium; Kruppel like factor 2; Liver; Portal hypertension; Simvastatin

Indexed keywords

ATORVASTATIN; COMPACTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KRUPPEL LIKE FACTOR 2; MEVALONIC ACID; MEVINOLIN; SIMVASTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHEAR STRESS; STELLATE CELL; UPREGULATION;

ANIMALS; CELL COMMUNICATION; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENE EXPRESSION; HEPATIC STELLATE CELLS; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERTENSION, PORTAL; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LIVER; LIVER CIRCULATION; LIVER CIRRHOSIS, EXPERIMENTAL; LOVASTATIN; MALE; PARACRINE COMMUNICATION; PYRROLES; RATS; RATS, WISTAR; SIMVASTATIN; STRESS, MECHANICAL;

EID: 84871211218     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.08.026     Document Type: Article

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