메뉴 건너뛰기




Volumn 20, Issue 1-2, 2015, Pages 9-25

Form and Function: how Estrogen and Progesterone Regulate the Mammary Epithelial Hierarchy

Author keywords

Breast; Estrogen; Mammary epithelial cells; Progenitor cells; Progesterone

Indexed keywords

CELL SURFACE MARKER; ESTROGEN; ESTROGEN RECEPTOR ALPHA; PROGESTERONE; PROGESTERONE RECEPTOR; TRANSCRIPTION FACTOR;

EID: 84943349671     PISSN: 10833021     EISSN: 15737039     Source Type: Journal    
DOI: 10.1007/s10911-015-9337-0     Document Type: Review
Times cited : (100)

References (171)
  • 1
    • 0023793193 scopus 로고
    • The effect of age and menstrual cycle upon proliferative activity of the normal human breast
    • COI: 1:STN:280:DyaL1M%2FgtVCrug%3D%3D, PID: 3166907
    • Potten CS, Watson RJ, Williams GT, Tickle S, Roberts SA, Harris M, et al. The effect of age and menstrual cycle upon proliferative activity of the normal human breast. Br J Cancer. 1988;58:163–70.
    • (1988) Br J Cancer , vol.58 , pp. 163-170
    • Potten, C.S.1    Watson, R.J.2    Williams, G.T.3    Tickle, S.4    Roberts, S.A.5    Harris, M.6
  • 2
    • 33644790809 scopus 로고    scopus 로고
    • Assessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle
    • COI: 1:CAS:528:DC%2BD2MXivVCgsrY%3D, PID: 15987425
    • Navarrete MA, Maier CM, Falzoni R, Quadros LG, Lima GR, Baracat EC, et al. Assessment of the proliferative, apoptotic and cellular renovation indices of the human mammary epithelium during the follicular and luteal phases of the menstrual cycle. Breast Cancer Res. 2005;7:R306–13.
    • (2005) Breast Cancer Res , vol.7 , pp. 306-313
    • Navarrete, M.A.1    Maier, C.M.2    Falzoni, R.3    Quadros, L.G.4    Lima, G.R.5    Baracat, E.C.6
  • 3
    • 0019447387 scopus 로고
    • Morphological evaluation of cell turnover in relation to the menstrual cycle in the “resting” human breast
    • COI: 1:STN:280:DyaL38%2FgtVehsg%3D%3D, PID: 7272186
    • Ferguson DJ, Anderson TJ. Morphological evaluation of cell turnover in relation to the menstrual cycle in the “resting” human breast. Br J Cancer. 1981;44:177–81.
    • (1981) Br J Cancer , vol.44 , pp. 177-181
    • Ferguson, D.J.1    Anderson, T.J.2
  • 4
    • 0019941326 scopus 로고
    • Cell turnover in the “resting” human breast: influence of parity, contraceptive pill, age and laterality
    • COI: 1:STN:280:DyaL3s%2Fit1ymtQ%3D%3D, PID: 7126427
    • Anderson TJ, Ferguson DJ, Raab GM. Cell turnover in the “resting” human breast: influence of parity, contraceptive pill, age and laterality. Br J Cancer. 1982;46:376–82.
    • (1982) Br J Cancer , vol.46 , pp. 376-382
    • Anderson, T.J.1    Ferguson, D.J.2    Raab, G.M.3
  • 5
    • 84899693434 scopus 로고    scopus 로고
    • Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling
    • PID: 24678808
    • Jindal S, Gao D, Bell P, Albrektsen G, Edgerton SM, Ambrosone CB, et al. Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling. Breast Cancer Res. 2014;16:R31.
    • (2014) Breast Cancer Res , vol.16 , pp. 31
    • Jindal, S.1    Gao, D.2    Bell, P.3    Albrektsen, G.4    Edgerton, S.M.5    Ambrosone, C.B.6
  • 6
    • 67651159312 scopus 로고    scopus 로고
    • Stem cells, self-renewal, and differentiation in the intestinal epithelium
    • PID: 18808327
    • van der Flier LG, Clevers H. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu Rev Physiol. 2009;71:241–60.
    • (2009) Annu Rev Physiol , vol.71 , pp. 241-260
    • van der Flier, L.G.1    Clevers, H.2
  • 7
    • 0038819885 scopus 로고    scopus 로고
    • Stem-cell hierarchy in skin cancer
    • COI: 1:CAS:528:DC%2BD3sXktFOnsb0%3D, PID: 12778133
    • Perez-Losada J, Balmain A. Stem-cell hierarchy in skin cancer. Nat Rev Cancer. 2003;3:434–43.
    • (2003) Nat Rev Cancer , vol.3 , pp. 434-443
    • Perez-Losada, J.1    Balmain, A.2
  • 8
    • 0036901598 scopus 로고    scopus 로고
    • Morphological changes in breast tissue with menstrual cycle
    • PID: 12481017
    • Ramakrishnan R, Khan SA, Badve S. Morphological changes in breast tissue with menstrual cycle. Mod Pathol. 2002;15:1348–56.
    • (2002) Mod Pathol , vol.15 , pp. 1348-1356
    • Ramakrishnan, R.1    Khan, S.A.2    Badve, S.3
  • 9
    • 0019493291 scopus 로고
    • The correlation of histologic changes in the human breast with the menstrual cycle
    • COI: 1:STN:280:DyaL3M3ltlSltQ%3D%3D, PID: 7258295
    • Vogel PM, Georgiade NG, Fetter BF, Vogel FS, McCarty Jr KS. The correlation of histologic changes in the human breast with the menstrual cycle. Am J Pathol. 1981;104:23–34.
    • (1981) Am J Pathol , vol.104 , pp. 23-34
    • Vogel, P.M.1    Georgiade, N.G.2    Fetter, B.F.3    Vogel, F.S.4    McCarty, K.S.5
  • 10
    • 0032925166 scopus 로고    scopus 로고
    • Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland
    • COI: 1:CAS:528:DyaK1MXktVarsbg%3D, PID: 10369068
    • Russo J, Ao X, Grill C, Russo IH. Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland. Breast Cancer Res Treat. 1999;53:217–27.
    • (1999) Breast Cancer Res Treat , vol.53 , pp. 217-227
    • Russo, J.1    Ao, X.2    Grill, C.3    Russo, I.H.4
  • 11
    • 0001397342 scopus 로고    scopus 로고
    • Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth
    • COI: 1:CAS:528:DyaK1cXislagur4%3D, PID: 9566307
    • Zeps N, Bentel JM, Papadimitriou JM, D’Antuono MF, Dawkins HJ. Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth. Differentiation. 1998;62:221–6.
    • (1998) Differentiation , vol.62 , pp. 221-226
    • Zeps, N.1    Bentel, J.M.2    Papadimitriou, J.M.3    D’Antuono, M.F.4    Dawkins, H.J.5
  • 12
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • COI: 1:CAS:528:DyaK2sXnsV2ktrY%3D, PID: 9371488
    • Clarke RB, Howell A, Potten CS, Anderson E. Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res. 1997;57:4987–91.
    • (1997) Cancer Res , vol.57 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 13
    • 1842634581 scopus 로고    scopus 로고
    • Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp1 sites
    • COI: 1:CAS:528:DC%2BD2cXjtVOit7c%3D, PID: 15084343
    • Petz LN, Ziegler YS, Schultz JR, Kim H, Kemper JK, Nardulli AM. Differential regulation of the human progesterone receptor gene through an estrogen response element half site and Sp1 sites. J Steroid Biochem Mol Biol. 2004;88:113–22.
    • (2004) J Steroid Biochem Mol Biol , vol.88 , pp. 113-122
    • Petz, L.N.1    Ziegler, Y.S.2    Schultz, J.R.3    Kim, H.4    Kemper, J.K.5    Nardulli, A.M.6
  • 14
    • 0037471227 scopus 로고    scopus 로고
    • Estrogen receptor alpha and Sp1 regulate progesterone receptor gene expression
    • COI: 1:CAS:528:DC%2BD3sXivFeqs78%3D, PID: 12706304
    • Schultz JR, Petz LN, Nardulli AM. Estrogen receptor alpha and Sp1 regulate progesterone receptor gene expression. Mol Cell Endocrinol. 2003;201:165–75.
    • (2003) Mol Cell Endocrinol , vol.201 , pp. 165-175
    • Schultz, J.R.1    Petz, L.N.2    Nardulli, A.M.3
  • 15
    • 12844262221 scopus 로고    scopus 로고
    • Cell- and ligand-specific regulation of promoters containing activator protein-1 and Sp1 sites by estrogen receptors alpha and beta
    • COI: 1:CAS:528:DC%2BD2cXhtFGgu7vE, PID: 15509581
    • Schultz JR, Petz LN, Nardulli AM. Cell- and ligand-specific regulation of promoters containing activator protein-1 and Sp1 sites by estrogen receptors alpha and beta. J Biol Chem. 2005;280:347–54.
    • (2005) J Biol Chem , vol.280 , pp. 347-354
    • Schultz, J.R.1    Petz, L.N.2    Nardulli, A.M.3
  • 16
    • 84894058500 scopus 로고    scopus 로고
    • Progesterone stimulates progenitor cells in normal human breast and breast cancer cells
    • COI: 1:CAS:528:DC%2BC2cXjtlCqsw%3D%3D, PID: 24395108
    • Hilton HN, Santucci N, Silvestri A, Kantimm S, Huschtscha LI, Graham JD, et al. Progesterone stimulates progenitor cells in normal human breast and breast cancer cells. Breast Cancer Res Treat. 2014;143:423–33.
    • (2014) Breast Cancer Res Treat , vol.143 , pp. 423-433
    • Hilton, H.N.1    Santucci, N.2    Silvestri, A.3    Kantimm, S.4    Huschtscha, L.I.5    Graham, J.D.6
  • 17
    • 84864352040 scopus 로고    scopus 로고
    • Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast
    • COI: 1:CAS:528:DC%2BC38XntFamsr4%3D, PID: 22580007
    • Hilton HN, Graham JD, Kantimm S, Santucci N, Cloosterman D, Huschtscha LI, et al. Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast. Mol Cell Endocrinol. 2012;361:191–201.
    • (2012) Mol Cell Endocrinol , vol.361 , pp. 191-201
    • Hilton, H.N.1    Graham, J.D.2    Kantimm, S.3    Santucci, N.4    Cloosterman, D.5    Huschtscha, L.I.6
  • 18
    • 84907997122 scopus 로고    scopus 로고
    • Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease
    • PID: 25261374
    • Hilton HN, Doan TB, Graham JD, Oakes SR, Silvestri A, Santucci N, et al. Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease. Oncotarget. 2014;5:8651–64.
    • (2014) Oncotarget , vol.5 , pp. 8651-8664
    • Hilton, H.N.1    Doan, T.B.2    Graham, J.D.3    Oakes, S.R.4    Silvestri, A.5    Santucci, N.6
  • 20
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • COI: 1:CAS:528:DC%2BD3sXlsFGntLk%3D, PID: 12829800
    • Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003;100:8418–23.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8418-8423
    • Sorlie, T.1    Tibshirani, R.2    Parker, J.3    Hastie, T.4    Marron, J.S.5    Nobel, A.6
  • 21
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • COI: 1:CAS:528:DC%2BD3MXntVGmsbo%3D, PID: 11553815
    • Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98:10869–74.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3    Aas, T.4    Geisler, S.5    Johnsen, H.6
  • 23
    • 54049111497 scopus 로고    scopus 로고
    • Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women
    • COI: 1:CAS:528:DC%2BD1cXpvFKmsLY%3D, PID: 18664548
    • Phipps AI, Malone KE, Porter PL, Daling JR, Li CI. Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2008;17:2078–86.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2078-2086
    • Phipps, A.I.1    Malone, K.E.2    Porter, P.L.3    Daling, J.R.4    Li, C.I.5
  • 24
    • 84862799485 scopus 로고    scopus 로고
    • Breast density, body mass index, and risk of tumor marker-defined subtypes of breast cancer
    • PID: 22366170
    • Phipps AI, Buist DS, Malone KE, Barlow WE, Porter PL, Kerlikowske K, et al. Breast density, body mass index, and risk of tumor marker-defined subtypes of breast cancer. Ann Epidemiol. 2012;22:340–8.
    • (2012) Ann Epidemiol , vol.22 , pp. 340-348
    • Phipps, A.I.1    Buist, D.S.2    Malone, K.E.3    Barlow, W.E.4    Porter, P.L.5    Kerlikowske, K.6
  • 25
    • 84874340180 scopus 로고    scopus 로고
    • Body mass index (BMI) and breast cancer: impact on tumor histopathologic features, cancer subtypes and recurrence rate in pre and postmenopausal women
    • PID: 23174088
    • Biglia N, Peano E, Sgandurra P, Moggio G, Pecchio S, Maggiorotto F, et al. Body mass index (BMI) and breast cancer: impact on tumor histopathologic features, cancer subtypes and recurrence rate in pre and postmenopausal women. Gynecol Endocrinol. 2013;29:263–7.
    • (2013) Gynecol Endocrinol , vol.29 , pp. 263-267
    • Biglia, N.1    Peano, E.2    Sgandurra, P.3    Moggio, G.4    Pecchio, S.5    Maggiorotto, F.6
  • 26
    • 0018219234 scopus 로고
    • Hormone receptors: their role in predicting prognosis and response to endocrine therapy
    • COI: 1:STN:280:DyaE1M%2FpslKhug%3D%3D, PID: 734443
    • McGuire WL. Hormone receptors: their role in predicting prognosis and response to endocrine therapy. Semin Oncol. 1978;5:428–33.
    • (1978) Semin Oncol , vol.5 , pp. 428-433
    • McGuire, W.L.1
  • 27
    • 32944482243 scopus 로고    scopus 로고
    • Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy
    • COI: 1:CAS:528:DC%2BD2MXht1WrsrrM, PID: 16234531
    • Cui X, Schiff R, Arpino G, Osborne CK, Lee AV. Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy. J Clin Oncol. 2005;23:7721–35.
    • (2005) J Clin Oncol , vol.23 , pp. 7721-7735
    • Cui, X.1    Schiff, R.2    Arpino, G.3    Osborne, C.K.4    Lee, A.V.5
  • 28
    • 0023751211 scopus 로고
    • Acquisition of estrogen-dependent progesterone receptors by normal mouse mammary gland. Ontogeny of mammary progesterone receptors
    • COI: 1:CAS:528:DyaL1cXltVGjsLc%3D, PID: 3398533
    • Haslam SZ. Acquisition of estrogen-dependent progesterone receptors by normal mouse mammary gland. Ontogeny of mammary progesterone receptors. J Steroid Biochem. 1988;31:9–13.
    • (1988) J Steroid Biochem , vol.31 , pp. 9-13
    • Haslam, S.Z.1
  • 29
    • 0036369222 scopus 로고    scopus 로고
    • Establishing a framework for the functional mammary gland: from endocrinology to morphology
    • PID: 12160083
    • Hovey RC, Trott JF, Vonderhaar BK. Establishing a framework for the functional mammary gland: from endocrinology to morphology. J Mammary Gland Biol Neoplasia. 2002;7:17–38.
    • (2002) J Mammary Gland Biol Neoplasia , vol.7 , pp. 17-38
    • Hovey, R.C.1    Trott, J.F.2    Vonderhaar, B.K.3
  • 30
    • 0032519554 scopus 로고    scopus 로고
    • Think globally, act locally: the making of a mouse mammary gland
    • COI: 1:CAS:528:DyaK1cXhtlShsLk%3D, PID: 9472013
    • Hennighausen L, Robinson GW. Think globally, act locally: the making of a mouse mammary gland. Genes Dev. 1998;12:449–55.
    • (1998) Genes Dev , vol.12 , pp. 449-455
    • Hennighausen, L.1    Robinson, G.W.2
  • 31
    • 0033846317 scopus 로고    scopus 로고
    • Oestrogen receptor alpha in female fetal, infant, and child mammary tissue
    • COI: 1:CAS:528:DC%2BD3cXlvFCrsLg%3D, PID: 10918221
    • Keeling JW, Ozer E, King G, Walker F. Oestrogen receptor alpha in female fetal, infant, and child mammary tissue. J Pathol. 2000;191:449–51.
    • (2000) J Pathol , vol.191 , pp. 449-451
    • Keeling, J.W.1    Ozer, E.2    King, G.3    Walker, F.4
  • 33
    • 4444310296 scopus 로고    scopus 로고
    • Development of the human breast
    • COI: 1:CAS:528:DC%2BD2cXntlSgsb0%3D, PID: 15351091
    • Russo J, Russo IH. Development of the human breast. Maturitas. 2004;49:2–15.
    • (2004) Maturitas , vol.49 , pp. 2-15
    • Russo, J.1    Russo, I.H.2
  • 34
    • 33144474647 scopus 로고    scopus 로고
    • Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland
    • COI: 1:CAS:528:DC%2BD28XhslGjsLs%3D, PID: 16452162
    • Mallepell S, Krust A, Chambon P, Brisken C. Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proc Natl Acad Sci U S A. 2006;103:2196–201.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2196-2201
    • Mallepell, S.1    Krust, A.2    Chambon, P.3    Brisken, C.4
  • 35
    • 35548936522 scopus 로고    scopus 로고
    • Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice
    • COI: 1:CAS:528:DC%2BD2sXhtVOns7jJ, PID: 17785410
    • Feng Y, Manka D, Wagner KU, Khan SA. Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proc Natl Acad Sci U S A. 2007;104:14718–23.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14718-14723
    • Feng, Y.1    Manka, D.2    Wagner, K.U.3    Khan, S.A.4
  • 36
    • 0036090478 scopus 로고    scopus 로고
    • Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha
    • COI: 1:CAS:528:DC%2BD38XjvFKjuro%3D, PID: 12021201
    • Mueller SO, Clark JA, Myers PH, Korach KS. Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha. Endocrinology. 2002;143:2357–65.
    • (2002) Endocrinology , vol.143 , pp. 2357-2365
    • Mueller, S.O.1    Clark, J.A.2    Myers, P.H.3    Korach, K.S.4
  • 37
    • 0032795261 scopus 로고    scopus 로고
    • Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
    • COI: 1:CAS:528:DyaK1MXks1Wqt7s%3D, PID: 10331984
    • Luetteke NC, Qiu TH, Fenton SE, Troyer KL, Riedel RF, Chang A, et al. Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. Development. 1999;126:2739–50.
    • (1999) Development , vol.126 , pp. 2739-2750
    • Luetteke, N.C.1    Qiu, T.H.2    Fenton, S.E.3    Troyer, K.L.4    Riedel, R.F.5    Chang, A.6
  • 38
    • 34248353890 scopus 로고    scopus 로고
    • Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development
    • COI: 1:CAS:528:DC%2BD2sXkt1emt7w%3D, PID: 17369357
    • Ciarloni L, Mallepell S, Brisken C. Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development. Proc Natl Acad Sci U S A. 2007;104:5455–60.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5455-5460
    • Ciarloni, L.1    Mallepell, S.2    Brisken, C.3
  • 39
    • 0029847417 scopus 로고    scopus 로고
    • Induction of ductal morphogenesis and lobular hyperplasia by amphiregulin in the mouse mammary gland
    • COI: 1:CAS:528:DyaK28XnsVOnu7o%3D, PID: 8959346
    • Kenney NJ, Smith GH, Rosenberg K, Cutler ML, Dickson RB. Induction of ductal morphogenesis and lobular hyperplasia by amphiregulin in the mouse mammary gland. Cell Growth Differ. 1996;7:1769–81.
    • (1996) Cell Growth Differ , vol.7 , pp. 1769-1781
    • Kenney, N.J.1    Smith, G.H.2    Rosenberg, K.3    Cutler, M.L.4    Dickson, R.B.5
  • 40
    • 0038814036 scopus 로고    scopus 로고
    • Effect of exogenous epidermal-like growth factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse
    • COI: 1:CAS:528:DC%2BD3sXktV2qurw%3D, PID: 12825851
    • Kenney NJ, Bowman A, Korach KS, Barrett JC, Salomon DS. Effect of exogenous epidermal-like growth factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse. Breast Cancer Res Treat. 2003;79:161–73.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 161-173
    • Kenney, N.J.1    Bowman, A.2    Korach, K.S.3    Barrett, J.C.4    Salomon, D.S.5
  • 41
    • 0032574830 scopus 로고    scopus 로고
    • A paracrine role for the epithelial progesterone receptor in mammary gland development
    • COI: 1:CAS:528:DyaK1cXivV2jsL0%3D, PID: 9560231
    • Brisken C, Park S, Vass T, Lydon JP, O’Malley BW, Weinberg RA. A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc Natl Acad Sci U S A. 1998;95:5076–81.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5076-5081
    • Brisken, C.1    Park, S.2    Vass, T.3    Lydon, J.P.4    O’Malley, B.W.5    Weinberg, R.A.6
  • 42
    • 0029115517 scopus 로고
    • Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities
    • COI: 1:CAS:528:DyaK2MXotlOjt74%3D, PID: 7557380
    • Lydon JP, Demayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery Jr CA, et al. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 1995;9:2266–78.
    • (1995) Genes Dev , vol.9 , pp. 2266-2278
    • Lydon, J.P.1    Demayo, F.J.2    Funk, C.R.3    Mani, S.K.4    Hughes, A.R.5    Montgomery, C.A.6
  • 43
    • 77649259667 scopus 로고    scopus 로고
    • Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland
    • COI: 1:CAS:528:DC%2BC3cXis1Cltb8%3D, PID: 20133621
    • Beleut M, Rajaram RD, Caikovski M, Ayyanan A, Germano D, Choi Y, et al. Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proc Natl Acad Sci U S A. 2010;107:2989–94.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2989-2994
    • Beleut, M.1    Rajaram, R.D.2    Caikovski, M.3    Ayyanan, A.4    Germano, D.5    Choi, Y.6
  • 44
    • 61349178831 scopus 로고    scopus 로고
    • The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse
    • Fernandez-Valdivia R, Mukherjee A, Ying Y, Li J, Paquet M, Demayo FJ, et al. The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. Dev Biol. 1999;328:127–39.
    • (1999) Dev Biol , vol.328 , pp. 127-139
    • Fernandez-Valdivia, R.1    Mukherjee, A.2    Ying, Y.3    Li, J.4    Paquet, M.5    Demayo, F.J.6
  • 45
    • 0034653649 scopus 로고    scopus 로고
    • Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling
    • COI: 1:CAS:528:DC%2BD3cXisVShu70%3D, PID: 10733525
    • Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, et al. Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev. 2000;14:650–4.
    • (2000) Genes Dev , vol.14 , pp. 650-654
    • Brisken, C.1    Heineman, A.2    Chavarria, T.3    Elenbaas, B.4    Tan, J.5    Dey, S.K.6
  • 46
    • 0029111934 scopus 로고
    • Cyclin D1 provides a link between development and oncogenesis in the retina and breast
    • COI: 1:CAS:528:DyaK2MXnvVWmtLc%3D, PID: 7664341
    • Sicinski P, Donaher JL, Parker SB, Li T, Fazeli A, Gardner H, et al. Cyclin D1 provides a link between development and oncogenesis in the retina and breast. Cell. 1995;82:621–30.
    • (1995) Cell , vol.82 , pp. 621-630
    • Sicinski, P.1    Donaher, J.L.2    Parker, S.B.3    Li, T.4    Fazeli, A.5    Gardner, H.6
  • 47
    • 0028889751 scopus 로고
    • Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
    • COI: 1:CAS:528:DyaK2MXos12it78%3D, PID: 7557388
    • Fantl V, Stamp G, Andrews A, Rosewell I, Dickson C. Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev. 1995;9:2364–72.
    • (1995) Genes Dev , vol.9 , pp. 2364-2372
    • Fantl, V.1    Stamp, G.2    Andrews, A.3    Rosewell, I.4    Dickson, C.5
  • 48
    • 1942499761 scopus 로고    scopus 로고
    • Escaping from Flatland: clinical and biological aspects of human mammary duct anatomy in three dimensions
    • PID: 15095476
    • Going JJ, Moffat DF. Escaping from Flatland: clinical and biological aspects of human mammary duct anatomy in three dimensions. J Pathol. 2004;203:538–44.
    • (2004) J Pathol , vol.203 , pp. 538-544
    • Going, J.J.1    Moffat, D.F.2
  • 49
    • 0035190378 scopus 로고    scopus 로고
    • Mammary gland architecture as a determining factor in the susceptibility of the human breast to cancer
    • COI: 1:STN:280:DC%2BD387nt1Ckuw%3D%3D, PID: 11906437
    • Russo J, Lynch H, Russo IH. Mammary gland architecture as a determining factor in the susceptibility of the human breast to cancer. Breast J. 2001;7:278–91.
    • (2001) Breast J , vol.7 , pp. 278-291
    • Russo, J.1    Lynch, H.2    Russo, I.H.3
  • 50
    • 0024323322 scopus 로고    scopus 로고
    • Influence of human breast development on the growth properties of primary cultures
    • Russo J, Mills MJ, Moussalli MJ, Russo IH. Influence of human breast development on the growth properties of primary cultures. In Vitro Cell Dev Biol. 1998;25:643–9.
    • (1998) In Vitro Cell Dev Biol , vol.25 , pp. 643-649
    • Russo, J.1    Mills, M.J.2    Moussalli, M.J.3    Russo, I.H.4
  • 51
    • 0026460191 scopus 로고
    • Influence of age and parity on the development of the human breast
    • COI: 1:STN:280:DyaK3s%2FpvFartg%3D%3D, PID: 1463860
    • Russo J, Rivera R, Russo IH. Influence of age and parity on the development of the human breast. Breast Cancer Res Treat. 1992;23:211–8.
    • (1992) Breast Cancer Res Treat , vol.23 , pp. 211-218
    • Russo, J.1    Rivera, R.2    Russo, I.H.3
  • 52
    • 84988841213 scopus 로고    scopus 로고
    • Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules
    • PID: 25315014
    • Arendt LM, Keller PJ, Skibinski A, Goncalves K, Naber SP, Buchsbaum RJ, et al. Anatomical localization of progenitor cells in human breast tissue reveals enrichment of uncommitted cells within immature lobules. Breast Cancer Res. 2014;16:453.
    • (2014) Breast Cancer Res , vol.16 , pp. 453
    • Arendt, L.M.1    Keller, P.J.2    Skibinski, A.3    Goncalves, K.4    Naber, S.P.5    Buchsbaum, R.J.6
  • 55
    • 4043142829 scopus 로고    scopus 로고
    • Normal breast lobular architecture in breast biopsy samples from breast cancer cases and benign disease controls
    • PID: 15567942
    • Ramakrishnan R, Gann PH, Wiley EL, Khurana KK, Khan SA. Normal breast lobular architecture in breast biopsy samples from breast cancer cases and benign disease controls. Breast Cancer Res Treat. 2004;86:259–68.
    • (2004) Breast Cancer Res Treat , vol.86 , pp. 259-268
    • Ramakrishnan, R.1    Gann, P.H.2    Wiley, E.L.3    Khurana, K.K.4    Khan, S.A.5
  • 56
    • 33847126689 scopus 로고    scopus 로고
    • Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
    • COI: 1:CAS:528:DC%2BD2sXhtFGlsbo%3D, PID: 17187062
    • Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, et al. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat Cell Biol. 2007;9:201–9.
    • (2007) Nat Cell Biol , vol.9 , pp. 201-209
    • Asselin-Labat, M.L.1    Sutherland, K.D.2    Barker, H.3    Thomas, R.4    Shackleton, M.5    Forrest, N.C.6
  • 57
    • 33751202983 scopus 로고    scopus 로고
    • GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland
    • COI: 1:CAS:528:DC%2BD28XhtlWktrzP, PID: 17129787
    • Kouros-Mehr H, Slorach EM, Sternlicht MD, Werb Z. GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland. Cell. 2006;127:1041–55.
    • (2006) Cell , vol.127 , pp. 1041-1055
    • Kouros-Mehr, H.1    Slorach, E.M.2    Sternlicht, M.D.3    Werb, Z.4
  • 58
    • 77953080874 scopus 로고    scopus 로고
    • FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis
    • COI: 1:CAS:528:DC%2BC3cXpvVOrsLc%3D, PID: 20501593
    • Bernardo GM, Lozada KL, Miedler JD, Harburg G, Hewitt SC, Mosley JD, et al. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development. 2010;137:2045–54.
    • (2010) Development , vol.137 , pp. 2045-2054
    • Bernardo, G.M.1    Lozada, K.L.2    Miedler, J.D.3    Harburg, G.4    Hewitt, S.C.5    Mosley, J.D.6
  • 59
    • 12244294465 scopus 로고    scopus 로고
    • Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development
    • COI: 1:CAS:528:DC%2BD38Xps1ehu7w%3D, PID: 12456789
    • Grimm SL, Seagroves TN, Kabotyanski EB, Hovey RC, Vonderhaar BK, Lydon JP, et al. Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol. 2002;16:2675–91.
    • (2002) Mol Endocrinol , vol.16 , pp. 2675-2691
    • Grimm, S.L.1    Seagroves, T.N.2    Kabotyanski, E.B.3    Hovey, R.C.4    Vonderhaar, B.K.5    Lydon, J.P.6
  • 60
    • 0034335414 scopus 로고    scopus 로고
    • C/EBPbeta (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development
    • COI: 1:CAS:528:DC%2BD3cXisFOqt78%3D, PID: 10707954
    • Seagroves TN, Lydon JP, Hovey RC, Vonderhaar BK, Rosen JM. C/EBPbeta (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development. Mol Endocrinol. 2000;14:359–68.
    • (2000) Mol Endocrinol , vol.14 , pp. 359-368
    • Seagroves, T.N.1    Lydon, J.P.2    Hovey, R.C.3    Vonderhaar, B.K.4    Rosen, J.M.5
  • 61
    • 77950558347 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland
    • COI: 1:CAS:528:DC%2BC3cXlvVGltbg%3D, PID: 20054865
    • LaMarca HL, Visbal AP, Creighton CJ, Liu H, Zhang Y, Behbod F, et al. CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells. 2010;28:535–44.
    • (2010) Stem Cells , vol.28 , pp. 535-544
    • LaMarca, H.L.1    Visbal, A.P.2    Creighton, C.J.3    Liu, H.4    Zhang, Y.5    Behbod, F.6
  • 62
    • 70350091566 scopus 로고    scopus 로고
    • Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A
    • COI: 1:CAS:528:DC%2BD1MXhtlCktbvK, PID: 19833766
    • Yamaji D, Na R, Feuermann Y, Pechhold S, Chen W, Robinson GW, et al. Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A. Genes Dev. 2009;23:2382–7.
    • (2009) Genes Dev , vol.23 , pp. 2382-2387
    • Yamaji, D.1    Na, R.2    Feuermann, Y.3    Pechhold, S.4    Chen, W.5    Robinson, G.W.6
  • 63
    • 0035969246 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium
    • COI: 1:CAS:528:DC%2BD3MXosVKitbg%3D, PID: 11706048
    • Miyoshi K, Shillingford JM, Smith GH, Grimm SL, Wagner KU, Oka T, et al. Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol. 2001;155:531–42.
    • (2001) J Cell Biol , vol.155 , pp. 531-542
    • Miyoshi, K.1    Shillingford, J.M.2    Smith, G.H.3    Grimm, S.L.4    Wagner, K.U.5    Oka, T.6
  • 64
    • 0031057929 scopus 로고    scopus 로고
    • Stat5a is mandatory for adult mammary gland development and lactogenesis
    • COI: 1:CAS:528:DyaK2sXpsVKqsg%3D%3D, PID: 9009201
    • Liu X, Robinson GW, Wagner KU, Garrett L, Wynshaw-Boris A, Hennighausen L. Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev. 1997;11:179–86.
    • (1997) Genes Dev , vol.11 , pp. 179-186
    • Liu, X.1    Robinson, G.W.2    Wagner, K.U.3    Garrett, L.4    Wynshaw-Boris, A.5    Hennighausen, L.6
  • 65
    • 77954530773 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5a mediates mammary ductal branching and proliferation in the nulliparous mouse
    • COI: 1:CAS:528:DC%2BC3cXnsVyqtbg%3D, PID: 20392833
    • Santos SJ, Haslam SZ, Conrad SE. Signal transducer and activator of transcription 5a mediates mammary ductal branching and proliferation in the nulliparous mouse. Endocrinology. 2010;151:2876–85.
    • (2010) Endocrinology , vol.151 , pp. 2876-2885
    • Santos, S.J.1    Haslam, S.Z.2    Conrad, S.E.3
  • 66
    • 37549032769 scopus 로고    scopus 로고
    • Estrogen and progesterone are critical regulators of Stat5a expression in the mouse mammary gland
    • COI: 1:CAS:528:DC%2BD1cXjtVyltA%3D%3D, PID: 17884938
    • Santos SJ, Haslam SZ, Conrad SE. Estrogen and progesterone are critical regulators of Stat5a expression in the mouse mammary gland. Endocrinology. 2008;149:329–38.
    • (2008) Endocrinology , vol.149 , pp. 329-338
    • Santos, S.J.1    Haslam, S.Z.2    Conrad, S.E.3
  • 68
    • 84875079780 scopus 로고    scopus 로고
    • Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
    • COI: 1:CAS:528:DC%2BC3sXntVClt7Y%3D, PID: 23462470
    • Lee HJ, Gallego-Ortega D, Ledger A, Schramek D, Joshi P, Szwarc MM, et al. Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells. Development. 2013;140:1397–401.
    • (2013) Development , vol.140 , pp. 1397-1401
    • Lee, H.J.1    Gallego-Ortega, D.2    Ledger, A.3    Schramek, D.4    Joshi, P.5    Szwarc, M.M.6
  • 70
    • 0035162210 scopus 로고    scopus 로고
    • Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects
    • COI: 1:CAS:528:DC%2BD3cXptVygt7k%3D, PID: 11133161
    • Gallego MI, Binart N, Robinson GW, Okagaki R, Coschigano KT, Perry J, et al. Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects. Dev Biol. 2001;229:163–75.
    • (2001) Dev Biol , vol.229 , pp. 163-175
    • Gallego, M.I.1    Binart, N.2    Robinson, G.W.3    Okagaki, R.4    Coschigano, K.T.5    Perry, J.6
  • 71
    • 58949085251 scopus 로고    scopus 로고
    • Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate
    • PID: 19063729
    • Kendrick H, Regan JL, Magnay FA, Grigoriadis A, Mitsopoulos C, Zvelebil M, et al. Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics. 2008;9:591.
    • (2008) BMC Genomics , vol.9 , pp. 591
    • Kendrick, H.1    Regan, J.L.2    Magnay, F.A.3    Grigoriadis, A.4    Mitsopoulos, C.5    Zvelebil, M.6
  • 72
    • 77955895963 scopus 로고    scopus 로고
    • Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
    • PID: 20346151
    • Lim E, Wu D, Pal B, Bouras T, Asselin-Labat ML, Vaillant F, et al. Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways. Breast Cancer Res. 2010;12:R21.
    • (2010) Breast Cancer Res , vol.12 , pp. 21
    • Lim, E.1    Wu, D.2    Pal, B.3    Bouras, T.4    Asselin-Labat, M.L.5    Vaillant, F.6
  • 73
    • 48649096223 scopus 로고    scopus 로고
    • Transcriptome analysis of the normal human mammary cell commitment and differentiation process
    • COI: 1:CAS:528:DC%2BD1cXovVSnsL8%3D, PID: 18593563
    • Raouf A, Zhao Y, To K, Stingl J, Delaney A, Barbara M, et al. Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell. 2008;3:109–18.
    • (2008) Cell Stem Cell , vol.3 , pp. 109-118
    • Raouf, A.1    Zhao, Y.2    To, K.3    Stingl, J.4    Delaney, A.5    Barbara, M.6
  • 74
    • 34548453199 scopus 로고    scopus 로고
    • Inference, validation, and dynamic modeling of transcription networks in multipotent hematopoietic cells
    • COI: 1:CAS:528:DC%2BD2sXpt1yktb0%3D, PID: 17442775
    • Soneji S, Huang S, Loose M, Donaldson IJ, Patient R, Gottgens B, et al. Inference, validation, and dynamic modeling of transcription networks in multipotent hematopoietic cells. Ann N Y Acad Sci. 2007;1106:30–40.
    • (2007) Ann N Y Acad Sci , vol.1106 , pp. 30-40
    • Soneji, S.1    Huang, S.2    Loose, M.3    Donaldson, I.J.4    Patient, R.5    Gottgens, B.6
  • 75
    • 84965810273 scopus 로고
    • Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
    • COI: 1:STN:280:DyaG1M%2Fpt1Oltg%3D%3D, PID: 13663040
    • DeOme KB, Faulkin Jr LJ, Bern HA, Blair PB. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Res. 1959;19:515–20.
    • (1959) Cancer Res , vol.19 , pp. 515-520
    • DeOme, K.B.1    Faulkin, L.J.2    Bern, H.A.3    Blair, P.B.4
  • 76
    • 0000947186 scopus 로고
    • Growth of mouse mammary glands in vivo after monolayer culture
    • COI: 1:STN:280:DyaF2M7jsFyltQ%3D%3D, PID: 14331183
    • Daniel CW, DeOme KB. Growth of mouse mammary glands in vivo after monolayer culture. Science. 1965;149:634–6.
    • (1965) Science , vol.149 , pp. 634-636
    • Daniel, C.W.1    DeOme, K.B.2
  • 77
    • 0031748344 scopus 로고    scopus 로고
    • An entire functional mammary gland may comprise the progeny from a single cell
    • COI: 1:CAS:528:DyaK1cXjvVanu7s%3D, PID: 9550724
    • Kordon EC, Smith GH. An entire functional mammary gland may comprise the progeny from a single cell. Development. 1998;125:1921–30.
    • (1998) Development , vol.125 , pp. 1921-1930
    • Kordon, E.C.1    Smith, G.H.2
  • 78
    • 84866532501 scopus 로고    scopus 로고
    • Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib
    • COI: 1:CAS:528:DC%2BC38Xhtl2lt73N, PID: 22811581
    • Lachenmayer A, Alsinet C, Savic R, Cabellos L, Toffanin S, Hoshida Y, et al. Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Clin Cancer Res. 2012;18:4997–5007.
    • (2012) Clin Cancer Res , vol.18 , pp. 4997-5007
    • Lachenmayer, A.1    Alsinet, C.2    Savic, R.3    Cabellos, L.4    Toffanin, S.5    Hoshida, Y.6
  • 79
    • 0037453008 scopus 로고    scopus 로고
    • X-inactivation patch size in human female tissue confounds the assessment of tumor clonality
    • COI: 1:CAS:528:DC%2BD3sXisVCntL0%3D, PID: 12610207
    • Novelli M, Cossu A, Oukrif D, Quaglia A, Lakhani S, Poulsom R, et al. X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. Proc Natl Acad Sci U S A. 2003;100:3311–4.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 3311-3314
    • Novelli, M.1    Cossu, A.2    Oukrif, D.3    Quaglia, A.4    Lakhani, S.5    Poulsom, R.6
  • 80
  • 81
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • COI: 1:CAS:528:DC%2BD28Xhs1KjsbY%3D, PID: 16395311
    • Stingl J, Eirew P, Ricketson I, Shackleton M, Vaillant F, Choi D, et al. Purification and unique properties of mammary epithelial stem cells. Nature. 2006;439:993–7.
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3    Shackleton, M.4    Vaillant, F.5    Choi, D.6
  • 82
    • 80855130470 scopus 로고    scopus 로고
    • Distinct stem cells contribute to mammary gland development and maintenance
    • PID: 21983963
    • Van Keymeulen A, Rocha AS, Ousset M, Beck B, Bouvencourt G, Rock J, et al. Distinct stem cells contribute to mammary gland development and maintenance. Nature. 2011;479:189–93.
    • (2011) Nature , vol.479 , pp. 189-193
    • Van Keymeulen, A.1    Rocha, A.S.2    Ousset, M.3    Beck, B.4    Bouvencourt, G.5    Rock, J.6
  • 84
    • 84924242267 scopus 로고    scopus 로고
    • Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
    • PID: 25467960
    • Boras-Granic K, Dann P, Wysolmerski JJ. Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland. Breast Cancer Res. 2014;16:487.
    • (2014) Breast Cancer Res , vol.16 , pp. 487
    • Boras-Granic, K.1    Dann, P.2    Wysolmerski, J.J.3
  • 85
    • 84866114887 scopus 로고    scopus 로고
    • Developmental stage and time dictate the fate of Wnt/beta-catenin-responsive stem cells in the mammary gland
    • PID: 22863533
    • van Amerongen R, Bowman AN, Nusse R. Developmental stage and time dictate the fate of Wnt/beta-catenin-responsive stem cells in the mammary gland. Cell Stem Cell. 2012;11:387–400.
    • (2012) Cell Stem Cell , vol.11 , pp. 387-400
    • van Amerongen, R.1    Bowman, A.N.2    Nusse, R.3
  • 86
    • 84922129231 scopus 로고    scopus 로고
    • Identification of multipotent mammary stem cells by protein C receptor expression
    • COI: 1:CAS:528:DC%2BC2cXhvVemtrrE, PID: 25327250
    • Wang D, Cai C, Dong X, Yu QC, Zhang XO, Yang L, et al. Identification of multipotent mammary stem cells by protein C receptor expression. Nature. 2015;517:81–4.
    • (2015) Nature , vol.517 , pp. 81-84
    • Wang, D.1    Cai, C.2    Dong, X.3    Yu, Q.C.4    Zhang, X.O.5    Yang, L.6
  • 87
    • 84902248072 scopus 로고    scopus 로고
    • Lineage tracing of mammary epithelial cells using cell-type-specific cre-expressing adenoviruses
    • COI: 1:CAS:528:DC%2BC2cXhtVWmt7vM, PID: 24936465
    • Tao L, van Bragt MP, Laudadio E, Li Z. Lineage tracing of mammary epithelial cells using cell-type-specific cre-expressing adenoviruses. Stem Cell Reports. 2014;2:770–9.
    • (2014) Stem Cell Reports , vol.2 , pp. 770-779
    • Tao, L.1    van Bragt, M.P.2    Laudadio, E.3    Li, Z.4
  • 88
    • 84894267586 scopus 로고    scopus 로고
    • In situ identification of bipotent stem cells in the mammary gland
    • COI: 1:CAS:528:DC%2BC2cXivVChtL8%3D, PID: 24463516
    • Rios AC, Fu NY, Lindeman GJ, Visvader JE. In situ identification of bipotent stem cells in the mammary gland. Nature. 2014;506:322–7.
    • (2014) Nature , vol.506 , pp. 322-327
    • Rios, A.C.1    Fu, N.Y.2    Lindeman, G.J.3    Visvader, J.E.4
  • 89
    • 65449123852 scopus 로고    scopus 로고
    • CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis
    • COI: 1:CAS:528:DC%2BD1MXmvVGitr0%3D, PID: 19411068
    • Pei XH, Bai F, Smith MD, Usary J, Fan C, Pai SY, et al. CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis. Cancer Cell. 2009;15:389–401.
    • (2009) Cancer Cell , vol.15 , pp. 389-401
    • Pei, X.H.1    Bai, F.2    Smith, M.D.3    Usary, J.4    Fan, C.5    Pai, S.Y.6
  • 90
    • 84875219386 scopus 로고    scopus 로고
    • Apoptosis differently affects lineage tracing of Lgr5 and Bmi1 intestinal stem cell populations
    • COI: 1:CAS:528:DC%2BC3sXis1yjsbw%3D, PID: 23415913
    • Zhu Y, Huang YF, Kek C, Bulavin DV. Apoptosis differently affects lineage tracing of Lgr5 and Bmi1 intestinal stem cell populations. Cell Stem Cell. 2013;12:298–303.
    • (2013) Cell Stem Cell , vol.12 , pp. 298-303
    • Zhu, Y.1    Huang, Y.F.2    Kek, C.3    Bulavin, D.V.4
  • 92
    • 84925777768 scopus 로고    scopus 로고
    • Mammary lineage tracing: the coming of age
    • COI: 1:CAS:528:DC%2BC2MXmtlWquw%3D%3D, PID: 25563489
    • Sale S, Pavelic K. Mammary lineage tracing: the coming of age. Cell Mol Life Sci. 2015;72:1577–83.
    • (2015) Cell Mol Life Sci , vol.72 , pp. 1577-1583
    • Sale, S.1    Pavelic, K.2
  • 93
    • 21044455192 scopus 로고    scopus 로고
    • Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer
    • COI: 1:CAS:528:DC%2BD2MXls1GjtL4%3D, PID: 15987465
    • Gusterson BA, Ross DT, Heath VJ, Stein T. Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer. Breast Cancer Res. 2005;7:143–8.
    • (2005) Breast Cancer Res , vol.7 , pp. 143-148
    • Gusterson, B.A.1    Ross, D.T.2    Heath, V.J.3    Stein, T.4
  • 95
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • COI: 1:CAS:528:DC%2BD1MXpt1Onsro%3D, PID: 19648928
    • Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med. 2009;15:907–13.
    • (2009) Nat Med , vol.15 , pp. 907-913
    • Lim, E.1    Vaillant, F.2    Wu, D.3    Forrest, N.C.4    Pal, B.5    Hart, A.H.6
  • 97
    • 79551614327 scopus 로고    scopus 로고
    • Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate
    • COI: 1:CAS:528:DC%2BC3MXhsFOktbk%3D, PID: 21295272
    • Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, et al. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell. 2011;8:149–63.
    • (2011) Cell Stem Cell , vol.8 , pp. 149-163
    • Proia, T.A.1    Keller, P.J.2    Gupta, P.B.3    Klebba, I.4    Jones, A.D.5    Sedic, M.6
  • 98
    • 0031674851 scopus 로고    scopus 로고
    • Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
    • COI: 1:STN:280:DyaK1cvhvVagsQ%3D%3D, PID: 9745711
    • Stingl J, Eaves CJ, Kuusk U, Emerman JT. Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast. Differentiation. 1998;63:201–13.
    • (1998) Differentiation , vol.63 , pp. 201-213
    • Stingl, J.1    Eaves, C.J.2    Kuusk, U.3    Emerman, J.T.4
  • 99
    • 0025765496 scopus 로고
    • Characterization in vitro of luminal and myoepithelial cells isolated from the human mammary gland by cell sorting
    • PID: 1833254
    • O’Hare MJ, Ormerod MG, Monaghan P, Lane EB, Gusterson BA. Characterization in vitro of luminal and myoepithelial cells isolated from the human mammary gland by cell sorting. Differentiation. 1991;46:209–21.
    • (1991) Differentiation , vol.46 , pp. 209-221
    • O’Hare, M.J.1    Ormerod, M.G.2    Monaghan, P.3    Lane, E.B.4    Gusterson, B.A.5
  • 100
    • 0034880458 scopus 로고    scopus 로고
    • Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
    • COI: 1:STN:280:DC%2BD3Mvns1yntw%3D%3D, PID: 11519870
    • Stingl J, Eaves CJ, Zandieh I, Emerman JT. Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Breast Cancer Res Treat. 2001;67:93–109.
    • (2001) Breast Cancer Res Treat , vol.67 , pp. 93-109
    • Stingl, J.1    Eaves, C.J.2    Zandieh, I.3    Emerman, J.T.4
  • 101
    • 67349191354 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase as a marker for stem cells
    • COI: 1:CAS:528:DC%2BD1cXhsVKhsrrJ, PID: 19075754
    • Moreb JS. Aldehyde dehydrogenase as a marker for stem cells. Curr Stem Cell Res Ther. 2008;3:237–46.
    • (2008) Curr Stem Cell Res Ther , vol.3 , pp. 237-246
    • Moreb, J.S.1
  • 102
    • 84856088648 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells
    • COI: 1:CAS:528:DC%2BC38Xjs1ShsL4%3D, PID: 22131125
    • Eirew P, Kannan N, Knapp DJ, Vaillant F, Emerman JT, Lindeman GJ, et al. Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells. Stem Cells. 2012;30:344–8.
    • (2012) Stem Cells , vol.30 , pp. 344-348
    • Eirew, P.1    Kannan, N.2    Knapp, D.J.3    Vaillant, F.4    Emerman, J.T.5    Lindeman, G.J.6
  • 103
    • 84902158569 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium
    • PID: 24887554
    • Honeth G, Lombardi S, Ginestier C, Hur M, Marlow R, Buchupalli B, et al. Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium. Breast Cancer Res. 2014;16:R52.
    • (2014) Breast Cancer Res , vol.16 , pp. 52
    • Honeth, G.1    Lombardi, S.2    Ginestier, C.3    Hur, M.4    Marlow, R.5    Buchupalli, B.6
  • 104
    • 84867639947 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of the luminal cell hierarchy of the mammary gland
    • COI: 1:CAS:528:DC%2BC3sXjsFSjt7k%3D, PID: 23088371
    • Shehata M, Teschendorff A, Sharp G, Novcic N, Russell A, Avril S, et al. Phenotypic and functional characterization of the luminal cell hierarchy of the mammary gland. Breast Cancer Res. 2012;14:R134.
    • (2012) Breast Cancer Res , vol.14 , pp. 134
    • Shehata, M.1    Teschendorff, A.2    Sharp, G.3    Novcic, N.4    Russell, A.5    Avril, S.6
  • 105
    • 33845982922 scopus 로고    scopus 로고
    • Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
    • COI: 1:CAS:528:DC%2BD2sXktVOnug%3D%3D, PID: 17190790
    • Sleeman KE, Kendrick H, Robertson D, Isacke CM, Ashworth A, Smalley MJ. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J Cell Biol. 2007;176:19–26.
    • (2007) J Cell Biol , vol.176 , pp. 19-26
    • Sleeman, K.E.1    Kendrick, H.2    Robertson, D.3    Isacke, C.M.4    Ashworth, A.5    Smalley, M.J.6
  • 106
    • 34547120690 scopus 로고    scopus 로고
    • Concise review: stem cell antigen-1: expression, function, and enigma
    • COI: 1:CAS:528:DC%2BD2sXntlWrsLY%3D, PID: 17379763
    • Holmes C, Stanford WL. Concise review: stem cell antigen-1: expression, function, and enigma. Stem Cells. 2007;25:1339–47.
    • (2007) Stem Cells , vol.25 , pp. 1339-1347
    • Holmes, C.1    Stanford, W.L.2
  • 107
    • 0036570144 scopus 로고    scopus 로고
    • Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population
    • COI: 1:CAS:528:DC%2BD38XjtVegu7w%3D, PID: 11969254
    • Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol. 2002;245:42–56.
    • (2002) Dev Biol , vol.245 , pp. 42-56
    • Welm, B.E.1    Tepera, S.B.2    Venezia, T.3    Graubert, T.A.4    Rosen, J.M.5    Goodell, M.A.6
  • 108
    • 84857115071 scopus 로고    scopus 로고
    • c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer
    • COI: 1:CAS:528:DC%2BC3MXovFyhtrc%3D, PID: 21765473
    • Regan JL, Kendrick H, Magnay FA, Vafaizadeh V, Groner B, Smalley MJ. c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer. Oncogene. 2012;31:869–83.
    • (2012) Oncogene , vol.31 , pp. 869-883
    • Regan, J.L.1    Kendrick, H.2    Magnay, F.A.3    Vafaizadeh, V.4    Groner, B.5    Smalley, M.J.6
  • 109
    • 0029868224 scopus 로고    scopus 로고
    • Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype
    • COI: 1:STN:280:DyaK28zislyntA%3D%3D, PID: 8738603
    • Smith GH. Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat. 1996;39:21–31.
    • (1996) Breast Cancer Res Treat , vol.39 , pp. 21-31
    • Smith, G.H.1
  • 110
    • 73649115686 scopus 로고    scopus 로고
    • Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis
    • COI: 1:CAS:528:DC%2BC3cXkvFKgs7k%3D, PID: 20129248
    • Jeselsohn R, Brown NE, Arendt L, Klebba I, Hu MG, Kuperwasser C, et al. Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis. Cancer Cell. 2010;17:65–76.
    • (2010) Cancer Cell , vol.17 , pp. 65-76
    • Jeselsohn, R.1    Brown, N.E.2    Arendt, L.3    Klebba, I.4    Hu, M.G.5    Kuperwasser, C.6
  • 111
    • 84892454445 scopus 로고    scopus 로고
    • The mammary stem cell hierarchy
    • COI: 1:CAS:528:DC%2BC2cXpslequr8%3D, PID: 24439805
    • Fu N, Lindeman GJ, Visvader JE. The mammary stem cell hierarchy. Curr Top Dev Biol. 2014;107:133–60.
    • (2014) Curr Top Dev Biol , vol.107 , pp. 133-160
    • Fu, N.1    Lindeman, G.J.2    Visvader, J.E.3
  • 112
    • 0038460529 scopus 로고    scopus 로고
    • Human mammary luminal epithelial cells contain progenitors to myoepithelial cells
    • COI: 1:CAS:528:DyaK1MXhtVehu70%3D, PID: 9918697
    • Pechoux C, Gudjonsson T, Ronnov-Jessen L, Bissell MJ, Petersen OW. Human mammary luminal epithelial cells contain progenitors to myoepithelial cells. Dev Biol. 1999;206:88–99.
    • (1999) Dev Biol , vol.206 , pp. 88-99
    • Pechoux, C.1    Gudjonsson, T.2    Ronnov-Jessen, L.3    Bissell, M.J.4    Petersen, O.W.5
  • 113
    • 0042671256 scopus 로고    scopus 로고
    • Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells
    • COI: 1:CAS:528:DC%2BD3sXlvFyqtbo%3D, PID: 12808020
    • Novaro V, Roskelley CD, Bissell MJ. Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells. J Cell Sci. 2003;116:2975–86.
    • (2003) J Cell Sci , vol.116 , pp. 2975-2986
    • Novaro, V.1    Roskelley, C.D.2    Bissell, M.J.3
  • 115
    • 67649669246 scopus 로고    scopus 로고
    • DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast
    • COI: 1:CAS:528:DC%2BD1MXotlCrsb8%3D, PID: 19342456
    • Graham JD, Mote PA, Salagame U, van Dijk JH, Balleine RL, Huschtscha LI, et al. DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast. Endocrinology. 2009;150:3318–26.
    • (2009) Endocrinology , vol.150 , pp. 3318-3326
    • Graham, J.D.1    Mote, P.A.2    Salagame, U.3    van Dijk, J.H.4    Balleine, R.L.5    Huschtscha, L.I.6
  • 116
    • 84860388993 scopus 로고    scopus 로고
    • Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays?
    • PID: 21635708
    • Vaillant F, Lindeman GJ, Visvader JE. Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays? Breast Cancer Res. 2011;13:108.
    • (2011) Breast Cancer Res , vol.13 , pp. 108
    • Vaillant, F.1    Lindeman, G.J.2    Visvader, J.E.3
  • 118
    • 0042693019 scopus 로고    scopus 로고
    • Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform
    • COI: 1:CAS:528:DC%2BD3sXmvVejt7Y%3D, PID: 12897242
    • Mulac-Jericevic B, Lydon JP, Demayo FJ, Conneely OM. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003;100:9744–9.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9744-9749
    • Mulac-Jericevic, B.1    Lydon, J.P.2    Demayo, F.J.3    Conneely, O.M.4
  • 119
    • 84902204202 scopus 로고    scopus 로고
    • Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells
    • COI: 1:CAS:528:DC%2BC2cXhtVWmt7jM, PID: 24936466
    • Lombardi S, Honeth G, Ginestier C, Shinomiya I, Marlow R, Buchupalli B, et al. Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells. Stem Cell Reports. 2014;2:780–93.
    • (2014) Stem Cell Reports , vol.2 , pp. 780-793
    • Lombardi, S.1    Honeth, G.2    Ginestier, C.3    Shinomiya, I.4    Marlow, R.5    Buchupalli, B.6
  • 120
    • 84924023108 scopus 로고    scopus 로고
    • Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk
    • COI: 1:CAS:528:DC%2BC2MXjsFCksrg%3D, PID: 25603931
    • Rajaram RD, Buric D, Caikovski M, Ayyanan A, Rougemont J, Shan J, et al. Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk. EMBO J. 2015;34:641–52.
    • (2015) EMBO J , vol.34 , pp. 641-652
    • Rajaram, R.D.1    Buric, D.2    Caikovski, M.3    Ayyanan, A.4    Rougemont, J.5    Shan, J.6
  • 121
    • 67149111600 scopus 로고    scopus 로고
    • The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development
    • PID: 19503830
    • Lindvall C, Zylstra CR, Evans N, West RA, Dykema K, Furge KA, et al. The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development. PLoS One. 2009;4:e5813.
    • (2009) PLoS One , vol.4 , pp. 5813
    • Lindvall, C.1    Zylstra, C.R.2    Evans, N.3    West, R.A.4    Dykema, K.5    Furge, K.A.6
  • 122
    • 68949154567 scopus 로고    scopus 로고
    • The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage
    • PID: 19672307
    • Badders NM, Goel S, Clark RJ, Klos KS, Kim S, Bafico A, et al. The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage. PLoS One. 2009;4:e6594.
    • (2009) PLoS One , vol.4 , pp. 6594
    • Badders, N.M.1    Goel, S.2    Clark, R.J.3    Klos, K.S.4    Kim, S.5    Bafico, A.6
  • 123
    • 84924534079 scopus 로고    scopus 로고
    • A progesterone-CXCR4 axis controls mammary progenitor cell fate in the adult gland CXCR4 function in mammary progenitors
    • COI: 1:CAS:528:DC%2BC2MXjtFShsrs%3D, PID: 25702641
    • Shiah YJ, Tharmapalan P, Casey AE, Joshi PA, McKee TD, Jackson HW, et al. A progesterone-CXCR4 axis controls mammary progenitor cell fate in the adult gland CXCR4 function in mammary progenitors. Stem Cell Reports. 2015;4:313–22.
    • (2015) Stem Cell Reports , vol.4 , pp. 313-322
    • Shiah, Y.J.1    Tharmapalan, P.2    Casey, A.E.3    Joshi, P.A.4    McKee, T.D.5    Jackson, H.W.6
  • 124
    • 35748943534 scopus 로고    scopus 로고
    • Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors
    • COI: 1:CAS:528:DC%2BD2sXhtl2nurrI, PID: 17996651
    • Gauthier ML, Berman HK, Miller C, Kozakeiwicz K, Chew K, Moore D, et al. Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors. Cancer Cell. 2007;12:479–91.
    • (2007) Cancer Cell , vol.12 , pp. 479-491
    • Gauthier, M.L.1    Berman, H.K.2    Miller, C.3    Kozakeiwicz, K.4    Chew, K.5    Moore, D.6
  • 125
    • 77953384898 scopus 로고    scopus 로고
    • Control of mammary stem cell function by steroid hormone signalling
    • COI: 1:CAS:528:DC%2BC3cXksFakurg%3D, PID: 20383121
    • Asselin-Labat ML, Vaillant F, Sheridan JM, Pal B, Wu D, Simpson ER, et al. Control of mammary stem cell function by steroid hormone signalling. Nature. 2010;465:798–802.
    • (2010) Nature , vol.465 , pp. 798-802
    • Asselin-Labat, M.L.1    Vaillant, F.2    Sheridan, J.M.3    Pal, B.4    Wu, D.5    Simpson, E.R.6
  • 126
    • 33745685565 scopus 로고    scopus 로고
    • Ovarian steroids and the human breast: regulation of stem cells and cell proliferation
    • COI: 1:CAS:528:DC%2BD28XmslCrsLs%3D, PID: 16806749
    • Clarke RB. Ovarian steroids and the human breast: regulation of stem cells and cell proliferation. Maturitas. 2006;54:327–34.
    • (2006) Maturitas , vol.54 , pp. 327-334
    • Clarke, R.B.1
  • 127
    • 33748134717 scopus 로고    scopus 로고
    • Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands
    • PID: 16882347
    • Booth BW, Smith GH. Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands. Breast Cancer Res. 2006;8:R49.
    • (2006) Breast Cancer Res , vol.8 , pp. 49
    • Booth, B.W.1    Smith, G.H.2
  • 128
    • 11144340909 scopus 로고    scopus 로고
    • A putative human breast stem cell population is enriched for steroid receptor-positive cells
    • COI: 1:CAS:528:DC%2BD2cXhtFGhsr3I, PID: 15617686
    • Clarke RB, Spence K, Anderson E, Howell A, Okano H, Potten CS. A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol. 2005;277:443–56.
    • (2005) Dev Biol , vol.277 , pp. 443-456
    • Clarke, R.B.1    Spence, K.2    Anderson, E.3    Howell, A.4    Okano, H.5    Potten, C.S.6
  • 129
    • 0346244047 scopus 로고    scopus 로고
    • Regulation of human breast epithelial stem cells
    • COI: 1:CAS:528:DC%2BD3sXpsFChtrw%3D, PID: 14521515
    • Clarke RB, Anderson E, Howell A, Potten CS. Regulation of human breast epithelial stem cells. Cell Prolif. 2003;36:45–58.
    • (2003) Cell Prolif , vol.36 , pp. 45-58
    • Clarke, R.B.1    Anderson, E.2    Howell, A.3    Potten, C.S.4
  • 130
    • 75949100576 scopus 로고    scopus 로고
    • Wnt signaling can substitute for estrogen to induce division of ERalpha-positive cells in a mouse mammary tumor model
    • COI: 1:CAS:528:DC%2BC3cXitValsr8%3D, PID: 19665836
    • Mastroianni M, Kim S, Kim YC, Esch A, Wagner C, Alexander CM. Wnt signaling can substitute for estrogen to induce division of ERalpha-positive cells in a mouse mammary tumor model. Cancer Lett. 2010;289:23–31.
    • (2010) Cancer Lett , vol.289 , pp. 23-31
    • Mastroianni, M.1    Kim, S.2    Kim, Y.C.3    Esch, A.4    Wagner, C.5    Alexander, C.M.6
  • 131
    • 84989898664 scopus 로고    scopus 로고
    • Transcriptome analysis of the hormone-sensing cells in mammary epithelial reveals dynamic changes in early pregnancy
    • PID: 25623114
    • de Silva D, Kunasegaran K, Ghosh S, Pietersen AM. Transcriptome analysis of the hormone-sensing cells in mammary epithelial reveals dynamic changes in early pregnancy. BMC Dev Biol. 2015;15:7.
    • (2015) BMC Dev Biol , vol.15 , pp. 7
    • de Silva, D.1    Kunasegaran, K.2    Ghosh, S.3    Pietersen, A.M.4
  • 133
  • 134
    • 84893192283 scopus 로고    scopus 로고
    • Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
    • COI: 1:CAS:528:DC%2BC3sXpsV2lsbw%3D, PID: 23770079
    • Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, et al. Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. Cell Stem Cell. 2013;13:117–30.
    • (2013) Cell Stem Cell , vol.13 , pp. 117-130
    • Choudhury, S.1    Almendro, V.2    Merino, V.F.3    Wu, Z.4    Maruyama, R.5    Su, Y.6
  • 135
    • 79955618757 scopus 로고    scopus 로고
    • The cell cycle inhibitor p27Kip(1) controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist
    • COI: 1:CAS:528:DC%2BC3MXhs1ChtbjJ, PID: 21478681
    • Menchon C, Edel MJ, Izpisua Belmonte JC. The cell cycle inhibitor p27Kip(1) controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist. Cell Cycle. 2011;10:1435–47.
    • (2011) Cell Cycle , vol.10 , pp. 1435-1447
    • Menchon, C.1    Edel, M.J.2    Izpisua Belmonte, J.C.3
  • 136
    • 0033694302 scopus 로고    scopus 로고
    • Stem cell repopulation efficiency but not pool size is governed by p27(kip1)
    • COI: 1:CAS:528:DC%2BD3cXotVaqtb8%3D, PID: 11062534
    • Cheng T, Rodrigues N, Dombkowski D, Stier S, Scadden DT. Stem cell repopulation efficiency but not pool size is governed by p27(kip1). Nat Med. 2000;6:1235–40.
    • (2000) Nat Med , vol.6 , pp. 1235-1240
    • Cheng, T.1    Rodrigues, N.2    Dombkowski, D.3    Stier, S.4    Scadden, D.T.5
  • 137
    • 34547960767 scopus 로고    scopus 로고
    • Alveolar progenitor cells develop in mouse mammary glands independent of pregnancy and lactation
    • COI: 1:CAS:528:DC%2BD2sXpsVGqtrs%3D, PID: 17443685
    • Booth BW, Boulanger CA, Smith GH. Alveolar progenitor cells develop in mouse mammary glands independent of pregnancy and lactation. J Cell Physiol. 2007;212:729–36.
    • (2007) J Cell Physiol , vol.212 , pp. 729-736
    • Booth, B.W.1    Boulanger, C.A.2    Smith, G.H.3
  • 138
    • 84892172236 scopus 로고    scopus 로고
    • New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells
    • PID: 24398145
    • Chang TH, Kunasegaran K, Tarulli GA, de Silva D, Voorhoeve PM, Pietersen AM. New insights into lineage restriction of mammary gland epithelium using parity-identified mammary epithelial cells. Breast Cancer Res. 2014;16:R1.
    • (2014) Breast Cancer Res , vol.16 , pp. 1
    • Chang, T.H.1    Kunasegaran, K.2    Tarulli, G.A.3    de Silva, D.4    Voorhoeve, P.M.5    Pietersen, A.M.6
  • 139
    • 33846935226 scopus 로고    scopus 로고
    • Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells
    • COI: 1:CAS:528:DC%2BD2sXhvVGgsbc%3D, PID: 17222404
    • Matulka LA, Triplett AA, Wagner KU. Parity-induced mammary epithelial cells are multipotent and express cell surface markers associated with stem cells. Dev Biol. 2007;303:29–44.
    • (2007) Dev Biol , vol.303 , pp. 29-44
    • Matulka, L.A.1    Triplett, A.A.2    Wagner, K.U.3
  • 140
    • 13244273440 scopus 로고    scopus 로고
    • Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression
    • COI: 1:CAS:528:DC%2BD2MXltVSgtQ%3D%3D, PID: 15580303
    • Boulanger CA, Wagner KU, Smith GH. Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression. Oncogene. 2005;24:552–60.
    • (2005) Oncogene , vol.24 , pp. 552-560
    • Boulanger, C.A.1    Wagner, K.U.2    Smith, G.H.3
  • 141
    • 4644342477 scopus 로고    scopus 로고
    • Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice
    • COI: 1:CAS:528:DC%2BD2cXnsFaitrg%3D, PID: 15286714
    • Henry MD, Triplett AA, Oh KB, Smith GH, Wagner KU. Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice. Oncogene. 2004;23:6980–5.
    • (2004) Oncogene , vol.23 , pp. 6980-6985
    • Henry, M.D.1    Triplett, A.A.2    Oh, K.B.3    Smith, G.H.4    Wagner, K.U.5
  • 142
    • 44849090936 scopus 로고    scopus 로고
    • Re-evaluation of mammary stem cell biology based on in vivo transplantation
    • PID: 18304381
    • Smith GH, Medina D. Re-evaluation of mammary stem cell biology based on in vivo transplantation. Breast Cancer Res. 2008;10:203.
    • (2008) Breast Cancer Res , vol.10 , pp. 203
    • Smith, G.H.1    Medina, D.2
  • 143
    • 0036339643 scopus 로고    scopus 로고
    • An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal
    • COI: 1:CAS:528:DC%2BD38XivFSiu7Y%3D, PID: 11880347
    • Wagner KU, Boulanger CA, Henry MD, Sgagias M, Hennighausen L, Smith GH. An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal. Development. 2002;129:1377–86.
    • (2002) Development , vol.129 , pp. 1377-1386
    • Wagner, K.U.1    Boulanger, C.A.2    Henry, M.D.3    Sgagias, M.4    Hennighausen, L.5    Smith, G.H.6
  • 144
    • 0035963435 scopus 로고    scopus 로고
    • Specific protection against breast cancers by cyclin D1 ablation
    • COI: 1:CAS:528:DC%2BD3MXltVClu7g%3D, PID: 11429595
    • Yu Q, Geng Y, Sicinski P. Specific protection against breast cancers by cyclin D1 ablation. Nature. 2001;411:1017–21.
    • (2001) Nature , vol.411 , pp. 1017-1021
    • Yu, Q.1    Geng, Y.2    Sicinski, P.3
  • 145
    • 30344479175 scopus 로고    scopus 로고
    • Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis
    • COI: 1:CAS:528:DC%2BD28XosFersg%3D%3D, PID: 16413468
    • Landis MW, Pawlyk BS, Li T, Sicinski P, Hinds PW. Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis. Cancer Cell. 2006;9:13–22.
    • (2006) Cancer Cell , vol.9 , pp. 13-22
    • Landis, M.W.1    Pawlyk, B.S.2    Li, T.3    Sicinski, P.4    Hinds, P.W.5
  • 146
    • 38849098280 scopus 로고    scopus 로고
    • Full-term pregnancy induces a specific genomic signature in the human breast
    • COI: 1:CAS:528:DC%2BD1cXmt12gtA%3D%3D, PID: 18199711
    • Russo J, Balogh GA, Russo IH. Full-term pregnancy induces a specific genomic signature in the human breast. Cancer Epidemiol Biomarkers Prev. 2008;17:51–66.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 51-66
    • Russo, J.1    Balogh, G.A.2    Russo, I.H.3
  • 147
    • 33646677290 scopus 로고    scopus 로고
    • Genomic signature induced by pregnancy in the human breast
    • COI: 1:CAS:528:DC%2BD28XhsFSgurk%3D, PID: 16391795
    • Balogh GA, Heulings R, Mailo DA, Russo PA, Sheriff F, Russo IH, et al. Genomic signature induced by pregnancy in the human breast. Int J Oncol. 2006;28:399–410.
    • (2006) Int J Oncol , vol.28 , pp. 399-410
    • Balogh, G.A.1    Heulings, R.2    Mailo, D.A.3    Russo, P.A.4    Sheriff, F.5    Russo, I.H.6
  • 148
    • 17144381276 scopus 로고    scopus 로고
    • Parity-induced changes in global gene expression in the human mammary gland
    • COI: 1:STN:280:DC%2BD2M3nt1OntA%3D%3D, PID: 15785316
    • Verlinden I, Gungor N, Wouters K, Janssens J, Raus J, Michiels L. Parity-induced changes in global gene expression in the human mammary gland. Eur J Cancer Prev. 2005;14:129–37.
    • (2005) Eur J Cancer Prev , vol.14 , pp. 129-137
    • Verlinden, I.1    Gungor, N.2    Wouters, K.3    Janssens, J.4    Raus, J.5    Michiels, L.6
  • 150
    • 84876800737 scopus 로고    scopus 로고
    • Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium
    • COI: 1:CAS:528:DC%2BC3sXptFyhs7g%3D, PID: 23621987
    • Meier-Abt F, Milani E, Roloff T, Brinkhaus H, Duss S, Meyer DS, et al. Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium. Breast Cancer Res. 2013;15:R36.
    • (2013) Breast Cancer Res , vol.15 , pp. 36
    • Meier-Abt, F.1    Milani, E.2    Roloff, T.3    Brinkhaus, H.4    Duss, S.5    Meyer, D.S.6
  • 151
    • 77956331142 scopus 로고    scopus 로고
    • Notch signaling in the regulation of stem cell self-renewal and differentiation
    • COI: 1:CAS:528:DC%2BC3cXht12jtLjI, PID: 20816402
    • Liu J, Sato C, Cerletti M, Wagers A. Notch signaling in the regulation of stem cell self-renewal and differentiation. Curr Top Dev Biol. 2010;92:367–409.
    • (2010) Curr Top Dev Biol , vol.92 , pp. 367-409
    • Liu, J.1    Sato, C.2    Cerletti, M.3    Wagers, A.4
  • 152
    • 84873185664 scopus 로고    scopus 로고
    • Stem cells living with a Notch
    • COI: 1:CAS:528:DC%2BC3sXkvVCrsL0%3D, PID: 23362343
    • Koch U, Lehal R, Radtke F. Stem cells living with a Notch. Development. 2013;140:689–704.
    • (2013) Development , vol.140 , pp. 689-704
    • Koch, U.1    Lehal, R.2    Radtke, F.3
  • 153
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • COI: 1:CAS:528:DC%2BD3sXktVGmt7s%3D, PID: 12756227
    • Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ, et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 2003;17:1253–70.
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5    Kawamura, M.J.6
  • 154
    • 77955657847 scopus 로고    scopus 로고
    • Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors
    • COI: 1:CAS:528:DC%2BC3cXns1Gju7w%3D, PID: 20562911
    • Ling H, Sylvestre JR, Jolicoeur P. Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors. Oncogene. 2010;29:4543–54.
    • (2010) Oncogene , vol.29 , pp. 4543-4554
    • Ling, H.1    Sylvestre, J.R.2    Jolicoeur, P.3
  • 155
    • 84877577009 scopus 로고    scopus 로고
    • Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages
    • COI: 1:CAS:528:DC%2BC3sXmt1Srtbw%3D, PID: 23604318
    • Sale S, Lafkas D, Artavanis-Tsakonas S. Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages. Nat Cell Biol. 2013;15:451–60.
    • (2013) Nat Cell Biol , vol.15 , pp. 451-460
    • Sale, S.1    Lafkas, D.2    Artavanis-Tsakonas, S.3
  • 156
    • 84885063044 scopus 로고    scopus 로고
    • Cyclin D1-dependent induction of luminal inflammatory breast tumors by activated notch3
    • COI: 1:CAS:528:DC%2BC3sXhsFGrsrjI, PID: 23928992
    • Ling H, Sylvestre JR, Jolicoeur P. Cyclin D1-dependent induction of luminal inflammatory breast tumors by activated notch3. Cancer Res. 2013;73:5963–73.
    • (2013) Cancer Res , vol.73 , pp. 5963-5973
    • Ling, H.1    Sylvestre, J.R.2    Jolicoeur, P.3
  • 157
    • 84855360178 scopus 로고    scopus 로고
    • Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor
    • COI: 1:CAS:528:DC%2BC3MXnsVajtrc%3D, PID: 21666720
    • Bruno RD, Boulanger CA, Smith GH. Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor. Oncogene. 2012;31:60–7.
    • (2012) Oncogene , vol.31 , pp. 60-67
    • Bruno, R.D.1    Boulanger, C.A.2    Smith, G.H.3
  • 158
    • 84862881087 scopus 로고    scopus 로고
    • Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling
    • COI: 1:CAS:528:DC%2BC38XhtFOhtLjP, PID: 22523003
    • Chakrabarti R, Wei Y, Romano RA, DeCoste C, Kang Y, Sinha S. Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling. Stem Cells. 2012;30:1496–508.
    • (2012) Stem Cells , vol.30 , pp. 1496-1508
    • Chakrabarti, R.1    Wei, Y.2    Romano, R.A.3    DeCoste, C.4    Kang, Y.5    Sinha, S.6
  • 160
    • 77953706705 scopus 로고    scopus 로고
    • Changes and tracking of mammographic density in relation to Pike’s model of breast tissue aging: a UK longitudinal study
    • COI: 1:CAS:528:DC%2BC3cXmsVGntLk%3D, PID: 19924817
    • McCormack VA, Perry NM, Vinnicombe SJ, dos Santos SI. Changes and tracking of mammographic density in relation to Pike’s model of breast tissue aging: a UK longitudinal study. Int J Cancer. 2010;127:452–61.
    • (2010) Int J Cancer , vol.127 , pp. 452-461
    • McCormack, V.A.1    Perry, N.M.2    Vinnicombe, S.J.3    dos Santos, S.I.4
  • 161
    • 34047106728 scopus 로고    scopus 로고
    • Age-related structural and metabolic changes in the pelvic reproductive end organs
    • PID: 17418150
    • Well D, Yang H, Houseni M, Iruvuri S, Alzeair S, Sansovini M, et al. Age-related structural and metabolic changes in the pelvic reproductive end organs. Semin Nucl Med. 2007;37:173–84.
    • (2007) Semin Nucl Med , vol.37 , pp. 173-184
    • Well, D.1    Yang, H.2    Houseni, M.3    Iruvuri, S.4    Alzeair, S.5    Sansovini, M.6
  • 162
    • 0021930760 scopus 로고
    • Effects of aging and obesity on aromatase activity of human adipose cells
    • COI: 1:CAS:528:DyaL2MXktlGjuw%3D%3D, PID: 3964790
    • Cleland WH, Mendelson CR, Simpson ER. Effects of aging and obesity on aromatase activity of human adipose cells. J Clin Endocrinol Metab. 1985;60:174–7.
    • (1985) J Clin Endocrinol Metab , vol.60 , pp. 174-177
    • Cleland, W.H.1    Mendelson, C.R.2    Simpson, E.R.3
  • 163
    • 0032980947 scopus 로고    scopus 로고
    • Oestrogen receptor expression in the normal and pre-cancerous breast
    • COI: 1:CAS:528:DyaK1MXltVKrur4%3D, PID: 10419589
    • Shoker BS, Jarvis C, Sibson DR, Walker C, Sloane JP. Oestrogen receptor expression in the normal and pre-cancerous breast. J Pathol. 1999;188:237–44.
    • (1999) J Pathol , vol.188 , pp. 237-244
    • Shoker, B.S.1    Jarvis, C.2    Sibson, D.R.3    Walker, C.4    Sloane, J.P.5
  • 164
    • 0036127795 scopus 로고    scopus 로고
    • Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging
    • COI: 1:CAS:528:DC%2BD38XhvVCitbo%3D, PID: 11897499
    • Shyamala G, Chou YC, Louie SG, Guzman RC, Smith GH, Nandi S. Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging. J Steroid Biochem Mol Biol. 2002;80:137–48.
    • (2002) J Steroid Biochem Mol Biol , vol.80 , pp. 137-148
    • Shyamala, G.1    Chou, Y.C.2    Louie, S.G.3    Guzman, R.C.4    Smith, G.H.5    Nandi, S.6
  • 165
    • 70349758953 scopus 로고    scopus 로고
    • Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes
    • COI: 1:CAS:528:DC%2BD1MXht1Kku7bE, PID: 19635758
    • Arendt LM, Evans LC, Rugowski DE, Garcia-Barchino MJ, Rui H, Schuler LA. Ovarian hormones are not required for PRL-induced mammary tumorigenesis, but estrogen enhances neoplastic processes. J Endocrinol. 2009;203:99–110.
    • (2009) J Endocrinol , vol.203 , pp. 99-110
    • Arendt, L.M.1    Evans, L.C.2    Rugowski, D.E.3    Garcia-Barchino, M.J.4    Rui, H.5    Schuler, L.A.6
  • 166
    • 62549090119 scopus 로고    scopus 로고
    • Prolactin-growth factor crosstalk reduces mammary estrogen responsiveness despite elevated ERalpha expression
    • COI: 1:CAS:528:DC%2BD1MXjs1Wgs7c%3D, PID: 19179608
    • Arendt LM, Grafwallner-Huseth TL, Schuler LA. Prolactin-growth factor crosstalk reduces mammary estrogen responsiveness despite elevated ERalpha expression. Am J Pathol. 2009;174:1065–74.
    • (2009) Am J Pathol , vol.174 , pp. 1065-1074
    • Arendt, L.M.1    Grafwallner-Huseth, T.L.2    Schuler, L.A.3
  • 167
    • 0026176009 scopus 로고
    • Proliferation of normal breast epithelial cells as shown by in vivo labeling with bromodeoxyuridine
    • COI: 1:STN:280:DyaK3M3ntlWisA%3D%3D, PID: 2053594
    • Christov K, Chew KL, Ljung BM, Waldman FM, Duarte LA, Goodson III WH, et al. Proliferation of normal breast epithelial cells as shown by in vivo labeling with bromodeoxyuridine. Am J Pathol. 1991;138:1371–7.
    • (1991) Am J Pathol , vol.138 , pp. 1371-1377
    • Christov, K.1    Chew, K.L.2    Ljung, B.M.3    Waldman, F.M.4    Duarte, L.A.5    Goodson, W.H.6
  • 168
    • 84863915064 scopus 로고    scopus 로고
    • Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia
    • COI: 1:CAS:528:DC%2BC38XhtVeltbnM, PID: 22552289
    • Garbe JC, Pepin F, Pelissier FA, Sputova K, Fridriksdottir AJ, Guo DE, et al. Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia. Cancer Res. 2012;72:3687–701.
    • (2012) Cancer Res , vol.72 , pp. 3687-3701
    • Garbe, J.C.1    Pepin, F.2    Pelissier, F.A.3    Sputova, K.4    Fridriksdottir, A.J.5    Guo, D.E.6
  • 170
    • 0032879195 scopus 로고    scopus 로고
    • The shape of age-incidence curves of female breast cancer by hormone-receptor status
    • COI: 1:STN:280:DyaK1MvlvVWqtQ%3D%3D, PID: 10530614
    • Yasui Y, Potter JD. The shape of age-incidence curves of female breast cancer by hormone-receptor status. Cancer Causes Control. 1999;10:431–7.
    • (1999) Cancer Causes Control , vol.10 , pp. 431-437
    • Yasui, Y.1    Potter, J.D.2
  • 171
    • 0036173553 scopus 로고    scopus 로고
    • The greater impact of menopause on ER- than ER+ breast cancer incidence: a possible explanation (United States)
    • PID: 11899120
    • Tarone RE, Chu KC. The greater impact of menopause on ER- than ER+ breast cancer incidence: a possible explanation (United States). Cancer Causes Control. 2002;13:7–14.
    • (2002) Cancer Causes Control , vol.13 , pp. 7-14
    • Tarone, R.E.1    Chu, K.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.