Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling

Genes and Development

Volumn 14, Issue 6, 2000, Pages 650-654

  Brisken, Cathrin ^a   Heineman, Anna ^a   Chavarria, Tony ^a   Elenbaas, Brian ^a   Tan, Jian ^b   Dey, Sudhansu K ^b   McMahon, Jill A ^c   McMahon, Andrew P ^c   Weinberg, Robert A ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Mammary gland; Morphogenesis; Progesterone function; Side branching; Wnt 4 signaling

Indexed keywords

PROGESTERONE;

ANIMAL TISSUE; ARTICLE; BREAST EPITHELIUM; GENE EXPRESSION; MAMMARY GLAND; MORPHOGENESIS; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MAMMARY GLANDS, ANIMAL; MICE; MICE, KNOCKOUT; PROGESTERONE; PROTO-ONCOGENE PROTEINS; RECEPTORS, PROGESTERONE; RNA PROBES; SIGNAL TRANSDUCTION; WNT PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0034653649     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Bjornson, C., R. Rietze, B. Reynolds, M. Magli, and A. Vescovi. 1999. Turning brain into blood: A hematopoietic fate adopted by adult neural stem cells in vivo. Science 283: 534-537.
2. Bocchinfuso, W., W. Hively, J. Couse, H. Varmus, and K. Korach. 1999. A mouse mammary tumor virus-Wnt-1 transgcne induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha. Cancer Res. 59: 1869-1876.
3. Bradbury, J.M., P.A. Edwards, C.C. Niemeyer, and T.C. Dale. 1995. Wnt-4 expression induces a pregnancy-like growth pattern in reconstituted mammary glands in virgin mice. Dev. Biol. 170: 553-563.
4. Brisken, C., S. Park, T. Vass, J. Lydon, B. O'Malley, and R. Weinberg. 1998. A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc. Natl. Acad. Sci. 95: 5076-5081.
5. Cadigan, K. and R. Nusse. 1997. Wnt signaling: A common theme in animal development. Genes & Dev. 11: 3286-3305.
6. Daniel, C.W. and K.B. DeOme. 1965. Growth of mouse mammary glands in vivo after monolayer culture. Science 149: 634-636.
7. Daniel, C.W. and G.B. Silberstein. 1987. Developmental biology of the mammary gland. In The mammary gland (ed. M.C. Neville and C. W. Daniel), pp. 3-36. Plenum Press, New York, NY.
8. Das, S., X. Wang, B. Paria, D. Damm, J. Abraham, M. Klagsbrun, G. Andrews, and S. Dey. 1994. Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: A possible ligand for interaction with blastocyst EGF-receptor in implantation. Development 120: 1071-1083.
9. DeOme, K.B., L.J. Faulkin, Jr., H.A. Bern, and P.B. Blair. 1959. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H Mice. Cancer Res. 19: 511-520.
10. Friedrich, G. and P. Soriano. 1993. Insertional mutagenesis by retroviruses and promoter traps in embryonic stem cells. Methods Enzymol. 225: 681-701.
11. Gavin, B.J. and A.P. McMahon. 1992. Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in post-natal development of the mammary gland. Mol. Cell. Biol. 12: 2418-2423.
12. Humphreys, R., J. Lydon, B. O'Malley, and J. Rosen. 1997. Mammary gland development is mediated by both stromal and epithelial progesterone receptors. Mol. Endocrinol. 11: 801-811.
13. Kispert, A., S. Vainio, and A. McMahon. 1998. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 125: 4225-4234.
14. Lee, F., T. Lane, A. Kuo, G. Shackleford, and P. Leder. 1995. Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice. Proc. Natl. Acad. Sci. 92: 2268-2272.
15. Lubahn, D., J. Moyer, T. Golding, J. Couse, K. Korach, and O. Smithies. 1993. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. 90: 11162-11166.
16. Lydon, J., M.F. De, C. Funk, S. Mani, A. Hughes, C.J. Montgomery, G. Shyamala, O. Conneely, and B. O'Malley. 1995. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes & Dev. 9: 2266-2278.
17. Mombaerts, P., J. Iacomini, R. Johnson, K. Herrup, S. Tonegawa, and V. Papaioannou. 1992. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68: 869-877.
18. Munsterberg, A., J. Kitajewski, D. Bumcrot, A. McMahon, and A. Lassar. 1995. Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic hHLH gene expression in the somite. Genes & Dev. 9: 2911-2922.
19. Nandi, S. 1958. Endocrine control of mammary-gland development in the C3H/He Crgl mouse. J. Natl. Cancer Inst. 21: 1039-1063.
20. Nusse, R. and H. Varmus. 1982. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 31: 99-109.
21. Nusse, R. and H. Varmus. 1992. Wnt genes. Cell 69: p1073-1087.
22. Roelink, H., E. Wagenaar, d.S.S. Lopes, and R. Nusse. 1990. Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. Proc Natl. Acad. Sci. 87: 4519-4523.
23. Said, T., O. Conneely, D. Medina, B. O'Malley, and J. Lydon. 1997. Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology 138: 3933-3939.
24. Schroeder, J. and D. Lee. 1998. Dynamic expression and activation of ERBB receptors in the developing mouse mammary gland. Cell Growth Differ. 9: 451-464.
25. Silberstein, G., H.K. Van, G. Shyamala, and C. Daniel. 1996. Progesterone receptors in the mouse mammary duct: Distribution and developmental regulation. Cell Growth Differ. 7: 945-952.
26. Stark, K., S. Vainio, G. Vassilcva, and A. McMahon. 1994. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372: 679-683.
27. Tan, J., S.K. Dey, and S.K. Das. 1999. Differential uterine expression of estrogen and progesterone receptors correlates with uterine preparation for implantation and decidualization in the mouse. Endocrinology 140: 5310-5321.
28. Tsukamoto, A., R. Grosschedl, R. Guzman, T. Parslow, and H. Varmus. 1988. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 55: 619-625.
29. Weber-Hall, S.J., D.J. Phippard, C.C. Niemeyer, and T.C. Dale. 1994. Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland. Differentiation 57: 205-214.