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Volumn 36, Issue 10, 2015, Pages 1200-1211

Genome-wide analysis of microRNA and mRNA expression signatures in cancer

Author keywords

biomarker; cancer; gene signature; genome wide analysis; miRNA; mRNA

Indexed keywords

MESSENGER RNA; MICRORNA; TUMOR MARKER;

EID: 84943265413     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2015.67     Document Type: Review
Times cited : (68)

References (197)
  • 1
    • 84864367909 scopus 로고    scopus 로고
    • Global cancer transitions according to the Human Development Index (2008-2030): A population-based study
    • Bray F, Jemal A, Grey N, Ferlay J, Forman D. Global cancer transitions according to the Human Development Index (2008-2030): a population-based study. Lancet Oncol 2012; 13: 790-801.
    • (2012) Lancet Oncol , vol.13 , pp. 790-801
    • Bray, F.1    Jemal, A.2    Grey, N.3    Ferlay, J.4    Forman, D.5
  • 2
    • 79961062492 scopus 로고    scopus 로고
    • Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
    • Cheung HW, Cowley GS, Weir BA, Boehm JS, Rusin S, Scott JA, et al. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc Natl Acad Sci USA 2011; 108: 12372-7.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 12372-12377
    • Cheung, H.W.1    Cowley, G.S.2    Weir, B.A.3    Boehm, J.S.4    Rusin, S.5    Scott, J.A.6
  • 3
    • 28544446695 scopus 로고    scopus 로고
    • Biomarkers in cancer staging, prognosis and treatment selection
    • Ludwig JA, Weinstein JN. Biomarkers in cancer staging, prognosis and treatment selection. Nat Rev Cancer 2005; 5: 845-56.
    • (2005) Nat Rev Cancer , vol.5 , pp. 845-856
    • Ludwig, J.A.1    Weinstein, J.N.2
  • 4
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843-54.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 5
    • 81855224576 scopus 로고    scopus 로고
    • Epigenetics and genetics MicroRNAs en route to the clinic: Progress in validating and targeting microRNAs for cancer therapy
    • Kasinski AL, Slack FJ. Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat Rev Cancer 2011; 11: 849-64.
    • (2011) Nat Rev Cancer , vol.11 , pp. 849-864
    • Kasinski, A.L.1    Slack, F.J.2
  • 6
  • 7
    • 84902464275 scopus 로고    scopus 로고
    • MicroRNAs and the cancer phenotype: Profiling, signatures and clinical implications
    • Stahlhut C, Slack FJ. MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications. Genome Med 2014; 5: 111.
    • (2014) Genome Med , vol.5 , pp. 111
    • Stahlhut, C.1    Slack, F.J.2
  • 8
    • 84905122848 scopus 로고    scopus 로고
    • MicroRNAs in cancer: Biomarkers, functions and therapy
    • Hayes J, Peruzzi PP, Lawler S. MicroRNAs in cancer: biomarkers, functions and therapy. Trends Mol Med 2014; 20: 460-9.
    • (2014) Trends Mol Med , vol.20 , pp. 460-469
    • Hayes, J.1    Peruzzi, P.P.2    Lawler, S.3
  • 10
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang B, Pan X, Cobb GP, Anderson TA. microRNAs as oncogenes and tumor suppressors. Dev Biol 2007; 302: 1-12.
    • (2007) Dev Biol , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 14
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006; 9: 189-98.
    • (2006) Cancer Cell , vol.9 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3    Seike, M.4    Kumamoto, K.5    Yi, M.6
  • 15
    • 84872080490 scopus 로고    scopus 로고
    • A microRNA panel to discriminate carcinomas from high-grade intraepithelial neoplasms in colonoscopy biopsy tissue
    • Wang S, Wang L, Bayaxi N, Li J, Verhaegh W, Janevski A, et al. A microRNA panel to discriminate carcinomas from high-grade intraepithelial neoplasms in colonoscopy biopsy tissue. Gut 2012; 62: 280-9.
    • (2012) Gut , vol.62 , pp. 280-289
    • Wang, S.1    Wang, L.2    Bayaxi, N.3    Li, J.4    Verhaegh, W.5    Janevski, A.6
  • 17
    • 39549094091 scopus 로고    scopus 로고
    • Differential expression of miRNAs in papillary thyroid carcinoma compared to multinodular goiter using formalin fixed paraffin embedded tissues
    • Tetzlaff MT, Liu A, Xu X, Master SR, Baldwin DA, Tobias JW, et al. Differential expression of miRNAs in papillary thyroid carcinoma compared to multinodular goiter using formalin fixed paraffin embedded tissues. Endocr Pathol 2007; 18: 163-73.
    • (2007) Endocr Pathol , vol.18 , pp. 163-173
    • Tetzlaff, M.T.1    Liu, A.2    Xu, X.3    Master, S.R.4    Baldwin, D.A.5    Tobias, J.W.6
  • 18
    • 84555202717 scopus 로고    scopus 로고
    • Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma
    • Zhou J, Yu L, Gao X, Hu J, Wang J, Dai Z, et al. Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol 2011; 29: 4781-8.
    • (2011) J Clin Oncol , vol.29 , pp. 4781-4788
    • Zhou, J.1    Yu, L.2    Gao, X.3    Hu, J.4    Wang, J.5    Dai, Z.6
  • 19
    • 84856018708 scopus 로고    scopus 로고
    • Genome-wide microRNA profiles identify miR-378 as a serum biomarker for early detection of gastric cancer
    • Liu H, Zhu L, Liu B, Yang L, Meng X, Zhang W, et al. Genome-wide microRNA profiles identify miR-378 as a serum biomarker for early detection of gastric cancer. Cancer Lett 2012; 316: 196-203.
    • (2012) Cancer Lett , vol.316 , pp. 196-203
    • Liu, H.1    Zhu, L.2    Liu, B.3    Yang, L.4    Meng, X.5    Zhang, W.6
  • 20
    • 78649887520 scopus 로고    scopus 로고
    • Expression profile of microRNAs in serum: A fingerprint for esophageal squamous cell carcinoma
    • Zhang C, Wang C, Chen X, Yang C, Li K, Wang J, et al. Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma. Clin Chem 2010; 56: 1871-9.
    • (2010) Clin Chem , vol.56 , pp. 1871-1879
    • Zhang, C.1    Wang, C.2    Chen, X.3    Yang, C.4    Li, K.5    Wang, J.6
  • 21
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
    • Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008; 18: 997-1006.
    • (2008) Cell Res , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6
  • 22
    • 79952101104 scopus 로고    scopus 로고
    • A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis
    • Liu R, Zhang C, Hu Z, Li G, Wang C, Yang C, et al. A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis. Eur J Cancer 2011; 47: 784-91.
    • (2011) Eur J Cancer , vol.47 , pp. 784-791
    • Liu, R.1    Zhang, C.2    Hu, Z.3    Li, G.4    Wang, C.5    Yang, C.6
  • 23
    • 78649972032 scopus 로고    scopus 로고
    • Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma
    • Li LM, Hu ZB, Zhou ZX, Chen X, Liu FY, Zhang JF, et al. Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma. Cancer Res 2010; 70: 9798-807.
    • (2010) Cancer Res , vol.70 , pp. 9798-9807
    • Li, L.M.1    Hu, Z.B.2    Zhou, Z.X.3    Chen, X.4    Liu, F.Y.5    Zhang, J.F.6
  • 25
    • 84862798121 scopus 로고    scopus 로고
    • De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer
    • Wu X, Somlo G, Yu Y, Palomares MR, Li AX, Zhou W, et al. De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer. J Transl Med 2011; 10: 42.
    • (2011) J Transl Med , vol.10 , pp. 42
    • Wu, X.1    Somlo, G.2    Yu, Y.3    Palomares, M.R.4    Li, A.X.5    Zhou, W.6
  • 26
    • 84857372726 scopus 로고    scopus 로고
    • Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer
    • Martens-Uzunova ES, Jalava SE, Dits NF, van Leenders GJ, Moller S, Trapman J, et al. Diagnostic and prognostic signatures from the small non-coding RNA transcriptome in prostate cancer. Oncogene 2011; 31: 978-91.
    • (2011) Oncogene , vol.31 , pp. 978-991
    • Martens-Uzunova, E.S.1    Jalava, S.E.2    Dits, N.F.3    Van Leenders, G.J.4    Moller, S.5    Trapman, J.6
  • 27
    • 77449135424 scopus 로고    scopus 로고
    • WHO classification of myeloid neoplasms and leukemia
    • Wandt H, Haferlach T, Thiede C, Ehninger G. WHO classification of myeloid neoplasms and leukemia. Blood 2010; 115: 748-9.
    • (2010) Blood , vol.115 , pp. 748-749
    • Wandt, H.1    Haferlach, T.2    Thiede, C.3    Ehninger, G.4
  • 28
    • 84928398136 scopus 로고    scopus 로고
    • A miRNA signature in human cord blood stem and progenitor cells as potential biomarker of specific acute myeloid leukemia subtypes
    • Cattaneo M, Pelosi E, Castelli G, Cerio AM, A DA, Porretti L, et al. A miRNA signature in human cord blood stem and progenitor cells as potential biomarker of specific acute myeloid leukemia subtypes. J Cell Physiol 2015; 230: 1770-80.
    • (2015) J Cell Physiol , vol.230 , pp. 1770-1780
    • Cattaneo, M.1    Pelosi, E.2    Castelli, G.3    Cerio, A.M.4    Da, A.5    Porretti, L.6
  • 29
    • 84863577404 scopus 로고    scopus 로고
    • Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7
    • Liu C, Kelnar K, Vlassov AV, Brown D, Wang J, Tang DG. Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Res 2012; 72: 3393-404.
    • (2012) Cancer Res , vol.72 , pp. 3393-3404
    • Liu, C.1    Kelnar, K.2    Vlassov, A.V.3    Brown, D.4    Wang, J.5    Tang, D.G.6
  • 30
    • 84878793883 scopus 로고    scopus 로고
    • Circulating microRNAs (cmiRNAs) as novel potential biomarkers for hepatocellular carcinoma
    • Qi J, Wang J, Katayama H, Sen S, Liu SM. Circulating microRNAs (cmiRNAs) as novel potential biomarkers for hepatocellular carcinoma. Neoplasma 2012; 60: 135-42.
    • (2012) Neoplasma , vol.60 , pp. 135-142
    • Qi, J.1    Wang, J.2    Katayama, H.3    Sen, S.4    Liu, S.M.5
  • 32
    • 57949110974 scopus 로고    scopus 로고
    • Detection of miR-106a in gastric carcinoma and its clinical significance
    • Xiao B, Guo J, Miao Y, Jiang Z, Huan R, Zhang Y, et al. Detection of miR-106a in gastric carcinoma and its clinical significance. Clin Chim Acta 2009; 400: 97-102.
    • (2009) Clin Chim Acta , vol.400 , pp. 97-102
    • Xiao, B.1    Guo, J.2    Miao, Y.3    Jiang, Z.4    Huan, R.5    Zhang, Y.6
  • 33
    • 77956934523 scopus 로고    scopus 로고
    • Down-regulation of miR-31 expression in gastric cancer tissues and its clinical significance
    • Zhang Y, Guo J, Li D, Xiao B, Miao Y, Jiang Z, et al. Down-regulation of miR-31 expression in gastric cancer tissues and its clinical significance. Med Oncol 2009; 27: 685-9.
    • (2009) Med Oncol , vol.27 , pp. 685-689
    • Zhang, Y.1    Guo, J.2    Li, D.3    Xiao, B.4    Miao, Y.5    Jiang, Z.6
  • 35
    • 84857037689 scopus 로고    scopus 로고
    • Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre-and post-operative plasma
    • Konishi H, Ichikawa D, Komatsu S, Shiozaki A, Tsujiura M, Takeshita H, et al. Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre-and post-operative plasma. Br J Cancer 2012; 106: 740-7.
    • (2012) Br J Cancer , vol.106 , pp. 740-747
    • Konishi, H.1    Ichikawa, D.2    Komatsu, S.3    Shiozaki, A.4    Tsujiura, M.5    Takeshita, H.6
  • 37
    • 34247862190 scopus 로고    scopus 로고
    • MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
    • Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP, et al. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 2007; 297: 1901-8.
    • (2007) JAMA , vol.297 , pp. 1901-1908
    • Bloomston, M.1    Frankel, W.L.2    Petrocca, F.3    Volinia, S.4    Alder, H.5    Hagan, J.P.6
  • 39
    • 77950560584 scopus 로고    scopus 로고
    • MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions
    • du Rieu MC, Torrisani J, Selves J, Al Saati T, Souque A, Dufresne M, et al. MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. Clin Chem 2010; 56: 603-12.
    • (2010) Clin Chem , vol.56 , pp. 603-612
    • Du Rieu, M.C.1    Torrisani, J.2    Selves, J.3    Al Saati, T.4    Souque, A.5    Dufresne, M.6
  • 40
    • 78650211014 scopus 로고    scopus 로고
    • Differentially expressed miRNAs in the plasma may provide a molecular signature for aggressive pancreatic cancer
    • Ali S, Almhanna K, Chen W, Philip PA, Sarkar FH. Differentially expressed miRNAs in the plasma may provide a molecular signature for aggressive pancreatic cancer. Am J Transl Res 2010; 3: 28-47.
    • (2010) Am J Transl Res , vol.3 , pp. 28-47
    • Ali, S.1    Almhanna, K.2    Chen, W.3    Philip, P.A.4    Sarkar, F.H.5
  • 42
    • 70449700281 scopus 로고    scopus 로고
    • MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease
    • Wang J. MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. Cancer Prev Res (Phila) 2009; 2: 807-13.
    • (2009) Cancer Prev Res (Phila) , vol.2 , pp. 807-813
    • Wang, J.1
  • 43
    • 37548999684 scopus 로고    scopus 로고
    • Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer
    • Sempere LF, Christensen M, Silahtaroglu A, Bak M, Heath CV, Schwartz G, et al. Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res 2007; 67: 11612-20.
    • (2007) Cancer Res , vol.67 , pp. 11612-11620
    • Sempere, L.F.1    Christensen, M.2    Silahtaroglu, A.3    Bak, M.4    Heath, C.V.5    Schwartz, G.6
  • 44
    • 65649087527 scopus 로고    scopus 로고
    • Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues
    • Hui AB, Shi W, Boutros PC, Miller N, Pintilie M, Fyles T, et al. Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest 2009; 89: 597-606.
    • (2009) Lab Invest , vol.89 , pp. 597-606
    • Hui, A.B.1    Shi, W.2    Boutros, P.C.3    Miller, N.4    Pintilie, M.5    Fyles, T.6
  • 45
    • 38849107424 scopus 로고    scopus 로고
    • The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
    • Huang Q, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S, et al. The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol 2008; 10: 202-10.
    • (2008) Nat Cell Biol , vol.10 , pp. 202-210
    • Huang, Q.1    Gumireddy, K.2    Schrier, M.3    Le Sage, C.4    Nagel, R.5    Nair, S.6
  • 46
    • 51749088101 scopus 로고    scopus 로고
    • Let-7a microRNA suppresses therapeuticsinduced cancer cell death by targeting caspase-3
    • Tsang WP, Kwok TT. Let-7a microRNA suppresses therapeuticsinduced cancer cell death by targeting caspase-3. Apoptosis 2008; 13: 1215-22.
    • (2008) Apoptosis , vol.13 , pp. 1215-1222
    • Tsang, W.P.1    Kwok, T.T.2
  • 47
    • 70449412171 scopus 로고    scopus 로고
    • MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma
    • Yamamoto Y. MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma. Biomarkers 2009; 14: 529-38.
    • (2009) Biomarkers , vol.14 , pp. 529-538
    • Yamamoto, Y.1
  • 48
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007; 133: 647-58.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1
  • 49
    • 78651417662 scopus 로고    scopus 로고
    • Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis
    • Xu J, Wu C, Che X, Wang L, Yu D, Zhang T, et al. Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog 2011; 50: 136-42.
    • (2011) Mol Carcinog , vol.50 , pp. 136-142
    • Xu, J.1    Wu, C.2    Che, X.3    Wang, L.4    Yu, D.5    Zhang, T.6
  • 50
    • 79251638583 scopus 로고    scopus 로고
    • Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies
    • Gui J, Tian Y, Wen X, Zhang W, Zhang P, Gao J, et al. Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies. Clin Sci (Lond) 2010; 120: 183-93.
    • (2010) Clin Sci (Lond) , vol.120 , pp. 183-193
    • Gui, J.1    Tian, Y.2    Wen, X.3    Zhang, W.4    Zhang, P.5    Gao, J.6
  • 52
    • 65349166324 scopus 로고    scopus 로고
    • Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma
    • Lebanony D, Benjamin H, Gilad S, Ezagouri M, Dov A, Ashkenazi K, et al. Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma. J Clin Oncol 2009; 27: 2030-7.
    • (2009) J Clin Oncol , vol.27 , pp. 2030-2037
    • Lebanony, D.1    Benjamin, H.2    Gilad, S.3    Ezagouri, M.4    Dov, A.5    Ashkenazi, K.6
  • 53
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P, et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007; 67: 9762-70.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6
  • 54
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103: 2257-61.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1
  • 55
    • 79957452077 scopus 로고    scopus 로고
    • Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer
    • Roth C, Kasimir-Bauer S, Pantel K, Schwarzenbach H. Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer. Mol Oncol 2011; 5: 281-91.
    • (2011) Mol Oncol , vol.5 , pp. 281-291
    • Roth, C.1    Kasimir-Bauer, S.2    Pantel, K.3    Schwarzenbach, H.4
  • 56
    • 62549125455 scopus 로고    scopus 로고
    • Exosomal microRNA: A diagnostic marker for lung cancer
    • Rabinowits G. Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer 2009; 10: 42-6.
    • (2009) Clin Lung Cancer , vol.10 , pp. 42-46
    • Rabinowits, G.1
  • 58
    • 79953712598 scopus 로고    scopus 로고
    • Vesicle-related microRNAs in plasma of nonsmall cell lung cancer patients and correlation with survival
    • Silva J, Garcia V, Zaballos A, Provencio M, Lombardia L, Almonacid L, et al. Vesicle-related microRNAs in plasma of nonsmall cell lung cancer patients and correlation with survival. Eur Respir J 2010; 37: 617-23.
    • (2010) Eur Respir J , vol.37 , pp. 617-623
    • Silva, J.1    Garcia, V.2    Zaballos, A.3    Provencio, M.4    Lombardia, L.5    Almonacid, L.6
  • 59
    • 38049100559 scopus 로고    scopus 로고
    • An androgen-regulated miRNA suppresses Bak1 expression and induces androgenindependent growth of prostate cancer cells
    • Shi XB, Xue L, Yang J, Ma AH, Zhao J, Xu M, et al. An androgen-regulated miRNA suppresses Bak1 expression and induces androgenindependent growth of prostate cancer cells. Proc Natl Acad Sci USA 2007; 104: 19983-8.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 19983-19988
    • Shi, X.B.1    Xue, L.2    Yang, J.3    Ma, A.H.4    Zhao, J.5    Xu, M.6
  • 60
    • 55549114664 scopus 로고    scopus 로고
    • The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
    • Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, Memeo L, et al. The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 2008; 14: 1271-7.
    • (2008) Nat Med , vol.14 , pp. 1271-1277
    • Bonci, D.1    Coppola, V.2    Musumeci, M.3    Addario, A.4    Giuffrida, R.5    Memeo, L.6
  • 61
    • 40449131878 scopus 로고    scopus 로고
    • Loss of mir-146a function in hormone-refractory prostate cancer
    • Lin SL, Chiang A, Chang D, Ying SY. Loss of mir-146a function in hormone-refractory prostate cancer. RNA 2008; 14: 417-24.
    • (2008) RNA , vol.14 , pp. 417-424
    • Lin, S.L.1    Chiang, A.2    Chang, D.3    Ying, S.Y.4
  • 63
    • 78249234164 scopus 로고    scopus 로고
    • MiR-34c is downregulated in prostate cancer and exerts tumor suppressive functions
    • Hagman Z, Larne O, Edsjo A, Bjartell A, Ehrnstrom RA, Ulmert D, et al. miR-34c is downregulated in prostate cancer and exerts tumor suppressive functions. Int J Cancer 2011; 127: 2768-76.
    • (2011) Int J Cancer , vol.127 , pp. 2768-2776
    • Hagman, Z.1    Larne, O.2    Edsjo, A.3    Bjartell, A.4    Ehrnstrom, R.A.5    Ulmert, D.6
  • 65
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002; 99: 15524-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 68
    • 84874782801 scopus 로고    scopus 로고
    • MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway
    • Hsieh IS, Chang KC, Tsai YT, Ke JY, Lu PJ, Lee KH, et al. MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway. Carcinogenesis 2012; 34: 530-8.
    • (2012) Carcinogenesis , vol.34 , pp. 530-538
    • Hsieh, I.S.1    Chang, K.C.2    Tsai, Y.T.3    Ke, J.Y.4    Lu, P.J.5    Lee, K.H.6
  • 70
    • 78751561643 scopus 로고    scopus 로고
    • Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients
    • Moltzahn F, Olshen AB, Baehner L, Peek A, Fong L, Stoppler H, et al. Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients. Cancer Res 2010; 71: 550-60.
    • (2010) Cancer Res , vol.71 , pp. 550-560
    • Moltzahn, F.1    Olshen, A.B.2    Baehner, L.3    Peek, A.4    Fong, L.5    Stoppler, H.6
  • 71
    • 78649837502 scopus 로고    scopus 로고
    • Circulating miRNAs are correlated with tumor progression in prostate cancer
    • Brase JC, Johannes M, Schlomm T, Falth M, Haese A, Steuber T, et al. Circulating miRNAs are correlated with tumor progression in prostate cancer. Int J Cancer 2010; 128: 608-16.
    • (2010) Int J Cancer , vol.128 , pp. 608-616
    • Brase, J.C.1    Johannes, M.2    Schlomm, T.3    Falth, M.4    Haese, A.5    Steuber, T.6
  • 73
    • 38749089854 scopus 로고    scopus 로고
    • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
    • Schetter AJ. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008; 299: 425-36.
    • (2008) JAMA , vol.299 , pp. 425-436
    • Schetter, A.J.1
  • 74
    • 70349976819 scopus 로고    scopus 로고
    • Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
    • Coulouarn C, Factor VM, Andersen JB, Durkin ME, Thorgeirsson SS. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene 2009; 28: 3526-36.
    • (2009) Oncogene , vol.28 , pp. 3526-3536
    • Coulouarn, C.1    Factor, V.M.2    Andersen, J.B.3    Durkin, M.E.4    Thorgeirsson, S.S.5
  • 75
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004; 64: 3753-6.
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1
  • 77
    • 80053190218 scopus 로고    scopus 로고
    • Prognostic impact of disseminated tumor cells and microRNA-17-92 cluster deregulation in gastrointestinal cancer
    • Valladares-Ayerbes M, Blanco M, Haz M, Medina V, Iglesias-Diaz P, Lorenzo-Patino MJ, et al. Prognostic impact of disseminated tumor cells and microRNA-17-92 cluster deregulation in gastrointestinal cancer. Int J Oncol 2011; 39: 1253-64.
    • (2011) Int J Oncol , vol.39 , pp. 1253-1264
    • Valladares-Ayerbes, M.1    Blanco, M.2    Haz, M.3    Medina, V.4    Iglesias-Diaz, P.5    Lorenzo-Patino, M.J.6
  • 78
    • 77951748235 scopus 로고    scopus 로고
    • Survival prediction of gastric cancer by a seven-microRNA signature
    • Li X, Zhang Y, Ding J, Wu K, Fan D. Survival prediction of gastric cancer by a seven-microRNA signature. Gut 2009; 59: 579-85.
    • (2009) Gut , vol.59 , pp. 579-585
    • Li, X.1    Zhang, Y.2    Ding, J.3    Wu, K.4    Fan, D.5
  • 79
    • 79959251756 scopus 로고    scopus 로고
    • Combination of hsa-miR-375 and hsa-miR-142-5p as a predictor for recurrence risk in gastric cancer patients following surgical resection
    • Zhang X, Yan Z, Zhang J, Gong L, Li W, Cui J, et al. Combination of hsa-miR-375 and hsa-miR-142-5p as a predictor for recurrence risk in gastric cancer patients following surgical resection. Ann Oncol 2011; 22: 2257-66.
    • (2011) Ann Oncol , vol.22 , pp. 2257-2266
    • Zhang, X.1    Yan, Z.2    Zhang, J.3    Gong, L.4    Li, W.5    Cui, J.6
  • 80
    • 77953950190 scopus 로고    scopus 로고
    • MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation
    • Yu J, Ohuchida K, Mizumoto K, Sato N, Kayashima T, Fujita H, et al. MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation. Mol Cancer 2010; 9: 169.
    • (2010) Mol Cancer , vol.9 , pp. 169
    • Yu, J.1    Ohuchida, K.2    Mizumoto, K.3    Sato, N.4    Kayashima, T.5    Fujita, H.6
  • 81
    • 79952441602 scopus 로고    scopus 로고
    • Detection of differentially expressed microRNAs in serum of pancreatic ductal adenocarcinoma patients: MiR-196a could be a potential marker for poor prognosis
    • Kong X, Du Y, Wang G, Gao J, Gong Y, Li L, et al. Detection of differentially expressed microRNAs in serum of pancreatic ductal adenocarcinoma patients: miR-196a could be a potential marker for poor prognosis. Dig Dis Sci 2010; 56: 602-9.
    • (2010) Dig Dis Sci , vol.56 , pp. 602-609
    • Kong, X.1    Du, Y.2    Wang, G.3    Gao, J.4    Gong, Y.5    Li, L.6
  • 82
    • 38049115129 scopus 로고    scopus 로고
    • Endogenous human microRNAs that suppress breast cancer metastasis
    • Tavazoie SF. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451: 147-52.
    • (2008) Nature , vol.451 , pp. 147-152
    • Tavazoie, S.F.1
  • 83
    • 66449095667 scopus 로고    scopus 로고
    • A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
    • Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szasz AM, Wang ZC, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009; 137: 1032-46.
    • (2009) Cell , vol.137 , pp. 1032-1046
    • Valastyan, S.1    Reinhardt, F.2    Benaich, N.3    Calogrias, D.4    Szasz, A.M.5    Wang, Z.C.6
  • 84
    • 55549120234 scopus 로고    scopus 로고
    • MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
    • Yan LX, Huang XF, Shao Q, Huang MY, Deng L, Wu QL, et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008; 14: 2348-60.
    • (2008) RNA , vol.14 , pp. 2348-2360
    • Yan, L.X.1    Huang, X.F.2    Shao, Q.3    Huang, M.Y.4    Deng, L.5    Wu, Q.L.6
  • 85
    • 78149433644 scopus 로고    scopus 로고
    • A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancer
    • Zhao H, Shen J, Medico L, Wang D, Ambrosone CB, Liu S. A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancer. PLoS ONE 2010; 5: e13735.
    • (2010) PLoS ONE , vol.5 , pp. e13735
    • Zhao, H.1    Shen, J.2    Medico, L.3    Wang, D.4    Ambrosone, C.B.5    Liu, S.6
  • 86
    • 78049339462 scopus 로고    scopus 로고
    • Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer
    • Roth C, Rack B, Muller V, Janni W, Pantel K, Schwarzenbach H. Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer. Breast Cancer Res 2010; 12: R90.
    • (2010) Breast Cancer Res , vol.12 , pp. R90
    • Roth, C.1    Rack, B.2    Muller, V.3    Janni, W.4    Pantel, K.5    Schwarzenbach, H.6
  • 87
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 2007; 26: 745-52.
    • (2007) Mol Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 88
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447: 1130-4.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    De Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 89
    • 84879419178 scopus 로고    scopus 로고
    • The biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemia
    • Malek SN. The biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemia. Oncogene 2012; 32: 2805-17.
    • (2012) Oncogene , vol.32 , pp. 2805-2817
    • Malek, S.N.1
  • 90
    • 78650977713 scopus 로고    scopus 로고
    • Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer
    • Asaga S, Kuo C, Nguyen T, Terpenning M, Giuliano AE, Hoon DS. Direct serum assay for microRNA-21 concentrations in early and advanced breast cancer. Clin Chem 2010; 57: 84-91.
    • (2010) Clin Chem , vol.57 , pp. 84-91
    • Asaga, S.1    Kuo, C.2    Nguyen, T.3    Terpenning, M.4    Giuliano, A.E.5    Hoon, D.S.6
  • 91
    • 77956117169 scopus 로고    scopus 로고
    • Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease
    • Heneghan HM, Miller N, Kelly R, Newell J, Kerin MJ. Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage disease. Oncologist 2010; 15: 673-82.
    • (2010) Oncologist , vol.15 , pp. 673-682
    • Heneghan, H.M.1    Miller, N.2    Kelly, R.3    Newell, J.4    Kerin, M.J.5
  • 92
    • 79952603697 scopus 로고    scopus 로고
    • Prognostic implications of miR-16 expression levels in resected nonsmall-cell lung cancer
    • Navarro A, Diaz T, Gallardo E, Vinolas N, Marrades RM, Gel B, et al. Prognostic implications of miR-16 expression levels in resected nonsmall-cell lung cancer. J Surg Oncol 2011; 103: 411-5.
    • (2011) J Surg Oncol , vol.103 , pp. 411-415
    • Navarro, A.1    Diaz, T.2    Gallardo, E.3    Vinolas, N.4    Marrades, R.M.5    Gel, B.6
  • 93
    • 77950498821 scopus 로고    scopus 로고
    • Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer
    • Hu Z, Chen X, Zhao Y, Tian T, Jin G, Shu Y, et al. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol 2010; 28: 1721-6.
    • (2010) J Clin Oncol , vol.28 , pp. 1721-1726
    • Hu, Z.1    Chen, X.2    Zhao, Y.3    Tian, T.4    Jin, G.5    Shu, Y.6
  • 97
    • 67549139894 scopus 로고    scopus 로고
    • Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients
    • Eitan R, Kushnir M, Lithwick-Yanai G, David MB, Hoshen M, Glezerman M, et al. Tumor microRNA expression patterns associated with resistance to platinum based chemotherapy and survival in ovarian cancer patients. Gynecol Oncol 2009; 114: 253-9.
    • (2009) Gynecol Oncol , vol.114 , pp. 253-259
    • Eitan, R.1    Kushnir, M.2    Lithwick-Yanai, G.3    David, M.B.4    Hoshen, M.5    Glezerman, M.6
  • 98
    • 67651039796 scopus 로고    scopus 로고
    • MiR-29b expression is associated with disease-free survival in patients with ovarian serous carcinoma
    • Flavin R, Smyth P, Barrett C, Russell S, Wen H, Wei J, et al. miR-29b expression is associated with disease-free survival in patients with ovarian serous carcinoma. Int J Gynecol Cancer 2009; 19: 641-7.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 641-647
    • Flavin, R.1    Smyth, P.2    Barrett, C.3    Russell, S.4    Wen, H.5    Wei, J.6
  • 99
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • Taylor DD, Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol 2008; 110: 13-21.
    • (2008) Gynecol Oncol , vol.110 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 100
    • 77953723274 scopus 로고    scopus 로고
    • Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrence
    • Spahn M, Kneitz S, Scholz CJ, Stenger N, Rudiger T, Strobel P, et al. Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrence. Int J Cancer 2009; 127: 394-403.
    • (2009) Int J Cancer , vol.127 , pp. 394-403
    • Spahn, M.1    Kneitz, S.2    Scholz, C.J.3    Stenger, N.4    Rudiger, T.5    Strobel, P.6
  • 102
    • 78951483439 scopus 로고    scopus 로고
    • Serum miRNA-21: Elevated levels in patients with metastatic hormonerefractory prostate cancer and potential predictive factor for the efficacy of docetaxel-based chemotherapy
    • Zhang HL, Yang LF, Zhu Y, Yao XD, Zhang SL, Dai B, et al. Serum miRNA-21: elevated levels in patients with metastatic hormonerefractory prostate cancer and potential predictive factor for the efficacy of docetaxel-based chemotherapy. Prostate 2010; 71: 326-31.
    • (2010) Prostate , vol.71 , pp. 326-331
    • Zhang, H.L.1    Yang, L.F.2    Zhu, Y.3    Yao, X.D.4    Zhang, S.L.5    Dai, B.6
  • 103
    • 79751473114 scopus 로고    scopus 로고
    • The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
    • Liu C, Kelnar K, Liu B, Chen X, Calhoun-Davis T, Li H, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011; 17: 211-5.
    • (2011) Nat Med , vol.17 , pp. 211-215
    • Liu, C.1    Kelnar, K.2    Liu, B.3    Chen, X.4    Calhoun-Davis, T.5    Li, H.6
  • 104
    • 84855813448 scopus 로고    scopus 로고
    • A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
    • Png KJ, Halberg N, Yoshida M, Tavazoie SF. A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 2011; 481: 190-4.
    • (2011) Nature , vol.481 , pp. 190-194
    • Png, K.J.1    Halberg, N.2    Yoshida, M.3    Tavazoie, S.F.4
  • 105
    • 84869017808 scopus 로고    scopus 로고
    • Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population
    • Zhan X, Wu W, Han B, Gao G, Qiao R, Lv J, et al. Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population. J Clin Lab Anal 2012; 26: 441-6.
    • (2012) J Clin Lab Anal , vol.26 , pp. 441-446
    • Zhan, X.1    Wu, W.2    Han, B.3    Gao, G.4    Qiao, R.5    Lv, J.6
  • 106
    • 84918841539 scopus 로고    scopus 로고
    • Circulating Epstein-Barr virus microRNAs miR-BART7 and miR-BART13 as biomarkers for nasopharyngeal carcinoma diagnosis and treatment
    • Zhang G, Zong J, Lin S, Verhoeven RJ, Tong S, Chen Y, et al. Circulating Epstein-Barr virus microRNAs miR-BART7 and miR-BART13 as biomarkers for nasopharyngeal carcinoma diagnosis and treatment. Int J Cancer 2015; 136: E301-12.
    • (2015) Int J Cancer , vol.136 , pp. E301-E312
    • Zhang, G.1    Zong, J.2    Lin, S.3    Verhoeven, R.J.4    Tong, S.5    Chen, Y.6
  • 108
    • 84907916718 scopus 로고    scopus 로고
    • A three-microRNA signature predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma
    • Saito M, Shiraishi K, Matsumoto K, Schetter AJ, Ogata-Kawata H, Tsuchiya N, et al. A three-microRNA signature predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma. Clin Cancer Res 2014; 20: 4784-93.
    • (2014) Clin Cancer Res , vol.20 , pp. 4784-4793
    • Saito, M.1    Shiraishi, K.2    Matsumoto, K.3    Schetter, A.J.4    Ogata-Kawata, H.5    Tsuchiya, N.6
  • 109
    • 0027282044 scopus 로고
    • Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993; 74: 597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3    Ding, L.4    Lindsten, T.5    Turka, L.A.6
  • 110
    • 0033569406 scopus 로고    scopus 로고
    • Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
    • Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999; 286: 531-7.
    • (1999) Science , vol.286 , pp. 531-537
    • Golub, T.R.1    Slonim, D.K.2    Tamayo, P.3    Huard, C.4    Gaasenbeek, M.5    Mesirov, J.P.6
  • 111
    • 84871959921 scopus 로고    scopus 로고
    • Biomarker discovery in non-small cell lung cancer: Integrating gene expression profiling, meta-analysis, and tissue microarray validation
    • Botling J, Edlund K, Lohr M, Hellwig B, Holmberg L, Lambe M, et al. Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation. Clin Cancer Res 2013; 19: 194-204.
    • (2013) Clin Cancer Res , vol.19 , pp. 194-204
    • Botling, J.1    Edlund, K.2    Lohr, M.3    Hellwig, B.4    Holmberg, L.5    Lambe, M.6
  • 112
    • 0036144678 scopus 로고    scopus 로고
    • Global gene expression analysis of gastric cancer by oligonucleotide microarrays
    • Hippo Y, Taniguchi H, Tsutsumi S, Machida N, Chong JM, Fukayama M, et al. Global gene expression analysis of gastric cancer by oligonucleotide microarrays. Cancer Res 2002; 62: 233-40.
    • (2002) Cancer Res , vol.62 , pp. 233-240
    • Hippo, Y.1    Taniguchi, H.2    Tsutsumi, S.3    Machida, N.4    Chong, J.M.5    Fukayama, M.6
  • 113
    • 0035363734 scopus 로고    scopus 로고
    • Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray
    • Bull JH, Ellison G, Patel A, Muir G, Walker M, Underwood M, et al. Identification of potential diagnostic markers of prostate cancer and prostatic intraepithelial neoplasia using cDNA microarray. Br J Cancer 2001; 84: 1512-9.
    • (2001) Br J Cancer , vol.84 , pp. 1512-1519
    • Bull, J.H.1    Ellison, G.2    Patel, A.3    Muir, G.4    Walker, M.5    Underwood, M.6
  • 114
    • 0242668421 scopus 로고    scopus 로고
    • Evaluation of clinical significance of TP53, BCL-2, BAX and MEK1 expression in 229 ovarian carcinomas treated with platinum-based regimen
    • Kupryjanczyk J, Szymanska T, Madry R, Timorek A, Stelmachow J, Karpinska G, et al. Evaluation of clinical significance of TP53, BCL-2, BAX and MEK1 expression in 229 ovarian carcinomas treated with platinum-based regimen. Br J Cancer 2003; 88: 848-54.
    • (2003) Br J Cancer , vol.88 , pp. 848-854
    • Kupryjanczyk, J.1    Szymanska, T.2    Madry, R.3    Timorek, A.4    Stelmachow, J.5    Karpinska, G.6
  • 115
    • 10044232731 scopus 로고    scopus 로고
    • Prognostic significance of p53, Her-2, and EGFR overexpression in borderline and epithelial ovarian cancer
    • Nielsen JS, Jakobsen E, Holund B, Bertelsen K, Jakobsen A. Prognostic significance of p53, Her-2, and EGFR overexpression in borderline and epithelial ovarian cancer. Int J Gynecol Cancer 2004; 14: 1086-96.
    • (2004) Int J Gynecol Cancer , vol.14 , pp. 1086-1096
    • Nielsen, J.S.1    Jakobsen, E.2    Holund, B.3    Bertelsen, K.4    Jakobsen, A.5
  • 116
    • 84891781479 scopus 로고    scopus 로고
    • Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer
    • Hou T, Yang C, Tong C, Zhang H, Xiao J, Li J. Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer. Int J Clin Exp Pathol 2013; 7: 280-7.
    • (2013) Int J Clin Exp Pathol , vol.7 , pp. 280-287
    • Hou, T.1    Yang, C.2    Tong, C.3    Zhang, H.4    Xiao, J.5    Li, J.6
  • 117
    • 84899635321 scopus 로고    scopus 로고
    • Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease
    • Brodsky AS, Fischer A, Miller DH, Vang S, MacLaughlan S, Wu HT, et al. Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease. PLoS One 2014; 9 : e94476.
    • (2014) PLoS One , vol.9 , pp. e94476
    • Brodsky, A.S.1    Fischer, A.2    Miller, D.H.3    Vang, S.4    MacLaughlan, S.5    Wu, H.T.6
  • 119
    • 0033968408 scopus 로고    scopus 로고
    • Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death
    • Hicks GG, Singh N, Nashabi A, Mai S, Bozek G, Klewes L, et al. Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death. Nat Genet 2000; 24: 175-9.
    • (2000) Nat Genet , vol.24 , pp. 175-179
    • Hicks, G.G.1    Singh, N.2    Nashabi, A.3    Mai, S.4    Bozek, G.5    Klewes, L.6
  • 120
    • 0035970039 scopus 로고    scopus 로고
    • Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics
    • Virtaneva K, Wright FA, Tanner SM, Yuan B, Lemon WJ, Caligiuri MA, et al. Expression profiling reveals fundamental biological differences in acute myeloid leukemia with isolated trisomy 8 and normal cytogenetics. Proc Natl Acad Sci USA 2001; 98: 1124-9.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1124-1129
    • Virtaneva, K.1    Wright, F.A.2    Tanner, S.M.3    Yuan, B.4    Lemon, W.J.5    Caligiuri, M.A.6
  • 121
    • 84977593798 scopus 로고    scopus 로고
    • An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in acute myeloid leukemia
    • Taskesen E, Staal FJ, Reinders MJ. An integrated approach of gene expression and DNA-methylation profiles of WNT signaling genes uncovers novel prognostic markers in acute myeloid leukemia. BMC Bioinformatics 2015; 16: S4.
    • (2015) BMC Bioinformatics , vol.16 , pp. S4
    • Taskesen, E.1    Staal, F.J.2    Reinders, M.J.3
  • 122
    • 0033521868 scopus 로고    scopus 로고
    • Elevated expression of eIF4E in confined early breast cancer lesions: Possible role of hypoxia
    • DeFatta RJ, Turbat-Herrera EA, Li BD, Anderson W, De Benedetti A. Elevated expression of eIF4E in confined early breast cancer lesions: possible role of hypoxia. Int J Cancer 1999; 80: 516-22.
    • (1999) Int J Cancer , vol.80 , pp. 516-522
    • DeFatta, R.J.1    Turbat-Herrera, E.A.2    Li, B.D.3    Anderson, W.4    De Benedetti, A.5
  • 123
    • 4444278397 scopus 로고    scopus 로고
    • Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway
    • Nathan CO, Amirghahari N, Abreo F, Rong X, Caldito G, Jones ML, et al. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway. Clin Cancer Res 2004; 10: 5820-7.
    • (2004) Clin Cancer Res , vol.10 , pp. 5820-5827
    • Nathan, C.O.1    Amirghahari, N.2    Abreo, F.3    Rong, X.4    Caldito, G.5    Jones, M.L.6
  • 126
    • 65949111747 scopus 로고    scopus 로고
    • EIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival
    • Graff JR, Konicek BW, Lynch RL, Dumstorf CA, Dowless MS, McNulty AM, et al. eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival. Cancer Res 2009; 69: 3866-73.
    • (2009) Cancer Res , vol.69 , pp. 3866-3873
    • Graff, J.R.1    Konicek, B.W.2    Lynch, R.L.3    Dumstorf, C.A.4    Dowless, M.S.5    McNulty, A.M.6
  • 127
    • 66049085709 scopus 로고    scopus 로고
    • Alternative splicing and tumor progression
    • Ghigna C, Valacca C, Biamonti G. Alternative splicing and tumor progression. Curr Genomics 2008; 9: 556-70.
    • (2008) Curr Genomics , vol.9 , pp. 556-570
    • Ghigna, C.1    Valacca, C.2    Biamonti, G.3
  • 129
    • 84894268206 scopus 로고    scopus 로고
    • Identification of alternative splicing events regulated by the oncogenic factor SRSF1 in lung cancer
    • de Miguel FJ, Sharma RD, Pajares MJ, Montuenga LM, Rubio A, Pio R. Identification of alternative splicing events regulated by the oncogenic factor SRSF1 in lung cancer. Cancer Res 2013; 74: 1105-15.
    • (2013) Cancer Res , vol.74 , pp. 1105-1115
    • De Miguel, F.J.1    Sharma, R.D.2    Pajares, M.J.3    Montuenga, L.M.4    Rubio, A.5    Pio, R.6
  • 130
    • 77957772409 scopus 로고    scopus 로고
    • Exonlevel transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities
    • Bemmo A, Dias C, Rose AA, Russo C, Siegel P, Majewski J. Exonlevel transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities. PLoS One 2010; 5: e11981.
    • (2010) PLoS One , vol.5 , pp. e11981
    • Bemmo, A.1    Dias, C.2    Rose, A.A.3    Russo, C.4    Siegel, P.5    Majewski, J.6
  • 131
    • 77955463831 scopus 로고    scopus 로고
    • Exon-level microarray analyses identify alternative splicing programs in breast cancer
    • Lapuk A, Marr H, Jakkula L, Pedro H, Bhattacharya S, Purdom E, et al. Exon-level microarray analyses identify alternative splicing programs in breast cancer. Mol Cancer Res 2010; 8: 961-74.
    • (2010) Mol Cancer Res , vol.8 , pp. 961-974
    • Lapuk, A.1    Marr, H.2    Jakkula, L.3    Pedro, H.4    Bhattacharya, S.5    Purdom, E.6
  • 133
    • 53549094961 scopus 로고    scopus 로고
    • Gene expression variation to predict 10-year survival in lymph-nodenegative breast cancer
    • Karlsson E, Delle U, Danielsson A, Olsson B, Abel F, Karlsson P, et al. Gene expression variation to predict 10-year survival in lymph-nodenegative breast cancer. BMC Cancer 2008; 8: 254.
    • (2008) BMC Cancer , vol.8 , pp. 254
    • Karlsson, E.1    Delle, U.2    Danielsson, A.3    Olsson, B.4    Abel, F.5    Karlsson, P.6
  • 134
    • 73349106829 scopus 로고    scopus 로고
    • Gene expressionbased classification and regulatory networks of pediatric acute lymphoblastic leukemia
    • Li Z, Zhang W, Wu M, Zhu S, Gao C, Sun L, et al. Gene expressionbased classification and regulatory networks of pediatric acute lymphoblastic leukemia. Blood 2009; 114: 4486-93.
    • (2009) Blood , vol.114 , pp. 4486-4493
    • Li, Z.1    Zhang, W.2    Wu, M.3    Zhu, S.4    Gao, C.5    Sun, L.6
  • 135
    • 79951506562 scopus 로고    scopus 로고
    • Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer
    • Salazar R, Roepman P, Capella G, Moreno V, Simon I, Dreezen C, et al. Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer. J Clin Oncol 2010; 29: 17-24.
    • (2010) J Clin Oncol , vol.29 , pp. 17-24
    • Salazar, R.1    Roepman, P.2    Capella, G.3    Moreno, V.4    Simon, I.5    Dreezen, C.6
  • 136
    • 84878113369 scopus 로고    scopus 로고
    • The shaping and functional consequences of the microRNA landscape in breast cancer
    • Dvinge H, Git A, Graf S, Salmon-Divon M, Curtis C, Sottoriva A, et al. The shaping and functional consequences of the microRNA landscape in breast cancer. Nature 2013; 497: 378-82.
    • (2013) Nature , vol.497 , pp. 378-382
    • Dvinge, H.1    Git, A.2    Graf, S.3    Salmon-Divon, M.4    Curtis, C.5    Sottoriva, A.6
  • 137
    • 84921731428 scopus 로고    scopus 로고
    • Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep wholetranscriptome sequencing
    • Lin KT, Shann YJ, Chau GY, Hsu CN, Huang CY. Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep wholetranscriptome sequencing. Oncogene 2014; 33: 4786-94.
    • (2014) Oncogene , vol.33 , pp. 4786-4794
    • Lin, K.T.1    Shann, Y.J.2    Chau, G.Y.3    Hsu, C.N.4    Huang, C.Y.5
  • 138
    • 84864660437 scopus 로고    scopus 로고
    • Transcriptome profiling of the cancer, adjacent non-tumor and distant normal tissues from a colorectal cancer patient by deep sequencing
    • Wu Y, Wang X, Wu F, Huang R, Xue F, Liang G, et al. Transcriptome profiling of the cancer, adjacent non-tumor and distant normal tissues from a colorectal cancer patient by deep sequencing. PLoS One 2012; 7: e41001.
    • (2012) PLoS One , vol.7 , pp. e41001
    • Wu, Y.1    Wang, X.2    Wu, F.3    Huang, R.4    Xue, F.5    Liang, G.6
  • 139
    • 84878665673 scopus 로고    scopus 로고
    • High-throughput RNA sequencing in B-cell lymphomas
    • Xiao W, Tran B, Staudt LM, Schmitz R. High-throughput RNA sequencing in B-cell lymphomas. Methods Mol Biol 2013; 971: 295-312.
    • (2013) Methods Mol Biol , vol.971 , pp. 295-312
    • Xiao, W.1    Tran, B.2    Staudt, L.M.3    Schmitz, R.4
  • 140
    • 84871713131 scopus 로고    scopus 로고
    • High-throughput sequencing of the melanoma genome
    • Kunz M, Dannemann M, Kelso J. High-throughput sequencing of the melanoma genome. Exp Dermatol 2013; 22: 10-7.
    • (2013) Exp Dermatol , vol.22 , pp. 10-17
    • Kunz, M.1    Dannemann, M.2    Kelso, J.3
  • 142
    • 84870899165 scopus 로고    scopus 로고
    • Deep sequence analysis of non-small cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations
    • Kalari KR, Rossell D, Necela BM, Asmann YW, Nair A, Baheti S, et al. Deep sequence analysis of non-small cell lung cancer: integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations. Front Oncol 2012; 2: 12.
    • (2012) Front Oncol , vol.2 , pp. 12
    • Kalari, K.R.1    Rossell, D.2    Necela, B.M.3    Asmann, Y.W.4    Nair, A.5    Baheti, S.6
  • 143
    • 84877600884 scopus 로고    scopus 로고
    • Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
    • De Sousa EMF, Wang X, Jansen M, Fessler E, Trinh A, de Rooij LP, et al. Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nat Med 2013; 19: 614-8.
    • (2013) Nat Med , vol.19 , pp. 614-618
    • De Sousa EMF1    Wang, X.2    Jansen, M.3    Fessler, E.4    Trinh, A.5    De Rooij, L.P.6
  • 144
    • 84877619075 scopus 로고    scopus 로고
    • A colorectal cancer classification system that associates cellular phenotype and responses to therapy
    • Sadanandam A, Lyssiotis CA, Homicsko K, Collisson EA, Gibb WJ, Wullschleger S, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat Med 2013; 19: 619-25.
    • (2013) Nat Med , vol.19 , pp. 619-625
    • Sadanandam, A.1    Lyssiotis, C.A.2    Homicsko, K.3    Collisson, E.A.4    Gibb, W.J.5    Wullschleger, S.6
  • 145
    • 12344267687 scopus 로고    scopus 로고
    • Gene expression signature with independent prognostic significance in epithelial ovarian cancer
    • Spentzos D, Levine DA, Ramoni MF, Joseph M, Gu X, Boyd J, et al. Gene expression signature with independent prognostic significance in epithelial ovarian cancer. J Clin Oncol 2004; 22: 4700-10.
    • (2004) J Clin Oncol , vol.22 , pp. 4700-4710
    • Spentzos, D.1    Levine, D.A.2    Ramoni, M.F.3    Joseph, M.4    Gu, X.5    Boyd, J.6
  • 146
    • 84908211259 scopus 로고    scopus 로고
    • Crenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo
    • Wang P, Song L, Ge H, Jin P, Jiang Y, Hu W, et al. Crenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo. Onco Targets Ther 2014; 7: 1761-8.
    • (2014) Onco Targets Ther , vol.7 , pp. 1761-1768
    • Wang, P.1    Song, L.2    Ge, H.3    Jin, P.4    Jiang, Y.5    Hu, W.6
  • 147
    • 84890467312 scopus 로고    scopus 로고
    • Targeting the PDGF signaling pathway in tumor treatment
    • Heldin CH. Targeting the PDGF signaling pathway in tumor treatment. Cell Commun Signal 2013; 11: 97.
    • (2013) Cell Commun Signal , vol.11 , pp. 97
    • Heldin, C.H.1
  • 148
    • 84857763426 scopus 로고    scopus 로고
    • Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma
    • Kridel R, Meissner B, Rogic S, Boyle M, Telenius A, Woolcock B, et al. Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood 2012; 119: 1963-71.
    • (2012) Blood , vol.119 , pp. 1963-1971
    • Kridel, R.1    Meissner, B.2    Rogic, S.3    Boyle, M.4    Telenius, A.5    Woolcock, B.6
  • 149
    • 84898828598 scopus 로고    scopus 로고
    • Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma
    • Brodtkorb M, Lingjaerde OC, Huse K, Troen G, Hystad M, Hilden VI, et al. Whole-genome integrative analysis reveals expression signatures predicting transformation in follicular lymphoma. Blood 2014; 123: 1051-4.
    • (2014) Blood , vol.123 , pp. 1051-1054
    • Brodtkorb, M.1    Lingjaerde, O.C.2    Huse, K.3    Troen, G.4    Hystad, M.5    Hilden, V.I.6
  • 154
    • 19944422061 scopus 로고    scopus 로고
    • A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
    • Paik S, Shak S, Tang G, Kim C, Baker J, Cronin M, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004; 351: 2817-26.
    • (2004) N Engl J Med , vol.351 , pp. 2817-2826
    • Paik, S.1    Shak, S.2    Tang, G.3    Kim, C.4    Baker, J.5    Cronin, M.6
  • 155
    • 84874572643 scopus 로고    scopus 로고
    • Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement
    • Azim HA Jr, Michiels S, Zagouri F, Delaloge S, Filipits M, Namer M, et al. Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement. Ann Oncol 2013; 24: 647-54.
    • (2013) Ann Oncol , vol.24 , pp. 647-654
    • Azim, Jr.H.A.1    Michiels, S.2    Zagouri, F.3    Delaloge, S.4    Filipits, M.5    Namer, M.6
  • 156
    • 77957582401 scopus 로고    scopus 로고
    • Relationship between tumor gene expression and recurrence in four independent studies of patients with stage II/III colon cancer treated with surgery alone or surgery plus adjuvant fluorouracil plus leucovorin
    • O'Connell MJ, Lavery I, Yothers G, Paik S, Clark-Langone KM, Lopatin M, et al. Relationship between tumor gene expression and recurrence in four independent studies of patients with stage II/III colon cancer treated with surgery alone or surgery plus adjuvant fluorouracil plus leucovorin. J Clin Oncol 2010; 28: 3937-44.
    • (2010) J Clin Oncol , vol.28 , pp. 3937-3944
    • O'Connell, M.J.1    Lavery, I.2    Yothers, G.3    Paik, S.4    Clark-Langone, K.M.5    Lopatin, M.6
  • 157
    • 79951506562 scopus 로고    scopus 로고
    • Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer
    • Salazar R, Roepman P, Capella G, Moreno V, Simon I, Dreezen C, et al. Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer. J Clin Oncol 2011; 29: 17-24.
    • (2011) J Clin Oncol , vol.29 , pp. 17-24
    • Salazar, R.1    Roepman, P.2    Capella, G.3    Moreno, V.4    Simon, I.5    Dreezen, C.6
  • 158
    • 84879114673 scopus 로고    scopus 로고
    • Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer
    • Maak M, Simon I, Nitsche U, Roepman P, Snel M, Glas AM, et al. Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer. Ann Surg 2013; 257: 1053-8.
    • (2013) Ann Surg , vol.257 , pp. 1053-1058
    • Maak, M.1    Simon, I.2    Nitsche, U.3    Roepman, P.4    Snel, M.5    Glas, A.M.6
  • 159
    • 74049087373 scopus 로고    scopus 로고
    • A blood-based biomarker panel for stratifying current risk for colorectal cancer
    • Marshall KW, Mohr S, Khettabi FE, Nossova N, Chao S, Bao W, et al. A blood-based biomarker panel for stratifying current risk for colorectal cancer. Int J Cancer 2010; 126: 1177-86.
    • (2010) Int J Cancer , vol.126 , pp. 1177-1186
    • Marshall, K.W.1    Mohr, S.2    Khettabi, F.E.3    Nossova, N.4    Chao, S.5    Bao, W.6
  • 160
    • 84873704094 scopus 로고    scopus 로고
    • Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior
    • Perez-Villamil B, Romera-Lopez A, Hernandez-Prieto S, Lopez-Campos G, Calles A, Lopez-Asenjo JA, et al. Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior. BMC Cancer 2012; 12: 260.
    • (2012) BMC Cancer , vol.12 , pp. 260
    • Perez-Villamil, B.1    Romera-Lopez, A.2    Hernandez-Prieto, S.3    Lopez-Campos, G.4    Calles, A.5    Lopez-Asenjo, J.A.6
  • 161
    • 84878302099 scopus 로고    scopus 로고
    • Gene expression classification of colon cancer into molecular subtypes: Characterization, validation, and prognostic value
    • Marisa L, de Reynies A, Duval A, Selves J, Gaub MP, Vescovo L, et al. Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med 2013; 10: e1001453.
    • (2013) PLoS Med , vol.10 , pp. e1001453
    • Marisa, L.1    De Reynies, A.2    Duval, A.3    Selves, J.4    Gaub, M.P.5    Vescovo, L.6
  • 162
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • Glinsky GV, Berezovska O, Glinskii AB. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005; 115: 1503-21.
    • (2005) J Clin Invest , vol.115 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 163
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from tumorigenic breast-cancer cells
    • Liu R, Wang X, Chen GY, Dalerba P, Gurney A, Hoey T, et al. The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med 2007; 356: 217-26.
    • (2007) N Engl J Med , vol.356 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3    Dalerba, P.4    Gurney, A.5    Hoey, T.6
  • 164
    • 79551669217 scopus 로고    scopus 로고
    • Genomewide analysis of microRNA and mRNA expression signatures in hydroxycamptothecin-resistant gastric cancer cells
    • Wu XM, Shao XQ, Meng XX, Zhang XN, Zhu L, Liu SX, et al. Genomewide analysis of microRNA and mRNA expression signatures in hydroxycamptothecin-resistant gastric cancer cells. Acta Pharmacol Sin 2011; 32: 259-69.
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 259-269
    • Wu, X.M.1    Shao, X.Q.2    Meng, X.X.3    Zhang, X.N.4    Zhu, L.5    Liu, S.X.6
  • 166
    • 84961528910 scopus 로고    scopus 로고
    • An integrated network of microRNA and gene expression in ovarian cancer
    • Quitadamo A, Tian L, Hall B, Shi X. An integrated network of microRNA and gene expression in ovarian cancer. BMC Bioinformatics 2015; 16: S5.
    • (2015) BMC Bioinformatics , vol.16 , pp. S5
    • Quitadamo, A.1    Tian, L.2    Hall, B.3    Shi, X.4
  • 167
    • 84901441961 scopus 로고    scopus 로고
    • Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition
    • Cava C, Bertoli G, Ripamonti M, Mauri G, Zoppis I, Della Rosa PA, et al. Integration of mRNA expression profile, copy number alterations, and microRNA expression levels in breast cancer to improve grade definition. PLoS One 2014; 9: e97681.
    • (2014) PLoS One , vol.9 , pp. e97681
    • Cava, C.1    Bertoli, G.2    Ripamonti, M.3    Mauri, G.4    Zoppis, I.5    Della Rosa, P.A.6
  • 168
    • 79957894183 scopus 로고    scopus 로고
    • mRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patients
    • Sieuwerts AM, Mostert B, Bolt-de Vries J, Peeters D, de Jongh FE, Stouthard JM, et al. mRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patients. Clin Cancer Res 2011; 17: 3600-18.
    • (2011) Clin Cancer Res , vol.17 , pp. 3600-3618
    • Sieuwerts, A.M.1    Mostert, B.2    Bolt-De Vries, J.3    Peeters, D.4    De Jongh, F.E.5    Stouthard, J.M.6
  • 169
    • 84902190191 scopus 로고    scopus 로고
    • A systematic analysis of miRNA-mRNA paired variations reveals widespread miRNA misregulation in breast cancer
    • Zhong L, Zhu K, Jin N, Wu D, Zhang J, Guo B, et al. A systematic analysis of miRNA-mRNA paired variations reveals widespread miRNA misregulation in breast cancer. Biomed Res Int 2014; 2014: 291280.
    • (2014) Biomed Res Int , vol.2014 , pp. 291280
    • Zhong, L.1    Zhu, K.2    Jin, N.3    Wu, D.4    Zhang, J.5    Guo, B.6
  • 170
    • 84920445650 scopus 로고    scopus 로고
    • Integrated miRNA and mRNA profiling of tumor-educated macrophages identifies prognostic subgroups in estrogen receptorpositive breast cancer
    • Bleckmann A, Leha A, Artmann S, Menck K, Salinas-Riester G, Binder C, et al. Integrated miRNA and mRNA profiling of tumor-educated macrophages identifies prognostic subgroups in estrogen receptorpositive breast cancer. Mol Oncol 2015; 9: 155-66.
    • (2015) Mol Oncol , vol.9 , pp. 155-166
    • Bleckmann, A.1    Leha, A.2    Artmann, S.3    Menck, K.4    Salinas-Riester, G.5    Binder, C.6
  • 171
    • 84925383411 scopus 로고    scopus 로고
    • Integrative investigation on breast cancer in ER PR and HER2-defined subgroups using mRNA and miRNA expression profiling
    • Dai X, Chen A, Bai Z. Integrative investigation on breast cancer in ER, PR and HER2-defined subgroups using mRNA and miRNA expression profiling. Sci Rep 2014; 4: 6566.
    • (2014) Sci Rep , vol.4 , pp. 6566
    • Dai, X.1    Chen, A.2    Bai, Z.3
  • 173
    • 84899067832 scopus 로고    scopus 로고
    • Gene expression profiling and bioinformatics analysis of gastric carcinoma
    • Liu N, Liu X, Zhou N, Wu Q, Zhou L, Li Q. Gene expression profiling and bioinformatics analysis of gastric carcinoma. Exp Mol Pathol 2014; 96: 361-6.
    • (2014) Exp Mol Pathol , vol.96 , pp. 361-366
    • Liu, N.1    Liu, X.2    Zhou, N.3    Wu, Q.4    Zhou, L.5    Li, Q.6
  • 174
    • 84928594541 scopus 로고    scopus 로고
    • MicroRNA-144 inhibits the metastasis of gastric cancer by targeting MET expression
    • Liu J, Xue H, Zhang J, Suo T, Xiang Y, Zhang W, et al. MicroRNA-144 inhibits the metastasis of gastric cancer by targeting MET expression. J Exp Clin Cancer Res 2015; 34: 35.
    • (2015) J Exp Clin Cancer Res , vol.34 , pp. 35
    • Liu, J.1    Xue, H.2    Zhang, J.3    Suo, T.4    Xiang, Y.5    Zhang, W.6
  • 175
    • 84938971144 scopus 로고    scopus 로고
    • Identifying microRNA-mRNA regulatory network in gemcitabine-resistant cells derived from human pancreatic cancer cells
    • Shen Y, Pan Y, Xu L, Chen L, Liu L, Chen H, et al. Identifying microRNA-mRNA regulatory network in gemcitabine-resistant cells derived from human pancreatic cancer cells. Tumour Biol 2015 ; 36: 4525-34.
    • (2015) Tumour Biol , vol.36 , pp. 4525-4534
    • Shen, Y.1    Pan, Y.2    Xu, L.3    Chen, L.4    Liu, L.5    Chen, H.6
  • 176
    • 84893836412 scopus 로고    scopus 로고
    • MiRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis
    • Huang WC, Chan SH, Jang TH, Chang JW, Ko YC, Yen TC, et al. miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis. Cancer Res 2014; 74: 751-64.
    • (2014) Cancer Res , vol.74 , pp. 751-764
    • Huang, W.C.1    Chan, S.H.2    Jang, T.H.3    Chang, J.W.4    Ko, Y.C.5    Yen, T.C.6
  • 177
    • 84906081399 scopus 로고    scopus 로고
    • A novel in silico reverse-transcriptomics-based identification and bloodbased validation of a panel of sub-type specific biomarkers in lung cancer
    • Barh D, Jain N, Tiwari S, Field JK, Padin-Iruegas E, Ruibal A, et al. A novel in silico reverse-transcriptomics-based identification and bloodbased validation of a panel of sub-type specific biomarkers in lung cancer. BMC Genomics 2013; 14: S5.
    • (2013) BMC Genomics , vol.14 , pp. S5
    • Barh, D.1    Jain, N.2    Tiwari, S.3    Field, J.K.4    Padin-Iruegas, E.5    Ruibal, A.6
  • 178
    • 84943340578 scopus 로고    scopus 로고
    • MiRNA-mRNA interaction network in non-small-cell lung cancer
    • Apr 11 [Epub ahead of print]
    • Ma R, Wang C, Wang J, Wang D, Xu J. miRNA-mRNA interaction network in non-small-cell lung cancer. Interdiscip Sci. 2015 Apr 11 [Epub ahead of print].
    • (2015) Interdiscip Sci.
    • Ma, R.1    Wang, C.2    Wang, J.3    Wang, D.4    Xu, J.5
  • 179
    • 84924529862 scopus 로고    scopus 로고
    • Novel candidate key drivers in the integrative network of genes, microRNAs, methylations, and copy number variations in squamous cell lung carcinoma
    • Huang T, Yang J, Cai YD. Novel candidate key drivers in the integrative network of genes, microRNAs, methylations, and copy number variations in squamous cell lung carcinoma. Biomed Res Int 2015; 2015: 358125.
    • (2015) Biomed Res Int , vol.2015 , pp. 358125
    • Huang, T.1    Yang, J.2    Cai, Y.D.3
  • 180
    • 84887098573 scopus 로고    scopus 로고
    • Screening biomarkers of prostate cancer by integrating microRNA and mRNA microarrays
    • Feng J, Huang C, Diao X, Fan M, Wang P, Xiao Y, et al. Screening biomarkers of prostate cancer by integrating microRNA and mRNA microarrays. Genet Test Mol Biomarkers 2013; 17: 807-13.
    • (2013) Genet Test Mol Biomarkers , vol.17 , pp. 807-813
    • Feng, J.1    Huang, C.2    Diao, X.3    Fan, M.4    Wang, P.5    Xiao, Y.6
  • 181
    • 84897486492 scopus 로고    scopus 로고
    • Identification of candidate miRNA biomarkers from miRNA regulatory network with application to prostate cancer
    • Zhang W, Zang J, Jing X, Sun Z, Yan W, Yang D, et al. Identification of candidate miRNA biomarkers from miRNA regulatory network with application to prostate cancer. J Transl Med 2014; 12: 66.
    • (2014) J Transl Med , vol.12 , pp. 66
    • Zhang, W.1    Zang, J.2    Jing, X.3    Sun, Z.4    Yan, W.5    Yang, D.6
  • 184
    • 79960728696 scopus 로고    scopus 로고
    • Comparative mRNA and microRNA expression profiling of three genitourinary cancers reveals common hallmarks and cancer-specific molecular events
    • Li X, Chen J, Hu X, Huang Y, Li Z, Zhou L, et al. Comparative mRNA and microRNA expression profiling of three genitourinary cancers reveals common hallmarks and cancer-specific molecular events. PloS ONE 2011; 6: e22570.
    • (2011) PloS ONE , vol.6 , pp. e22570
    • Li, X.1    Chen, J.2    Hu, X.3    Huang, Y.4    Li, Z.5    Zhou, L.6
  • 186
    • 84874456193 scopus 로고    scopus 로고
    • A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells
    • Luo D, Wilson JM, Harvel N, Liu J, Pei L, Huang S, et al. A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells. J Transl Med 2013; 11: 57.
    • (2013) J Transl Med , vol.11 , pp. 57
    • Luo, D.1    Wilson, J.M.2    Harvel, N.3    Liu, J.4    Pei, L.5    Huang, S.6
  • 187
    • 84863095465 scopus 로고    scopus 로고
    • MiRNA-mRNA correlation-network modules in human prostate cancer and the differences between primary and metastatic tumor subtypes
    • Zhang W, Edwards A, Fan W, Flemington EK, Zhang K. miRNA-mRNA correlation-network modules in human prostate cancer and the differences between primary and metastatic tumor subtypes. PLoS One 2014; 7: e40130.
    • (2014) PLoS One , vol.7 , pp. e40130
    • Zhang, W.1    Edwards, A.2    Fan, W.3    Flemington, E.K.4    Zhang, K.5
  • 188
    • 84879033423 scopus 로고    scopus 로고
    • Constructing higher-order miRNA-mRNA interaction networks in prostate cancer via hypergraph-based learning
    • Kim SJ, Ha JW, Zhang BT. Constructing higher-order miRNA-mRNA interaction networks in prostate cancer via hypergraph-based learning. BMC Syst Biol 2013; 7: 47.
    • (2013) BMC Syst Biol , vol.7 , pp. 47
    • Kim, S.J.1    Ha, J.W.2    Zhang, B.T.3
  • 189
    • 84888117735 scopus 로고    scopus 로고
    • MiRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients
    • Zadran S, Remacle F, Levine RD. miRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients. Proc Natl Acad Sci USA 2013; 110: 19160-5.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 19160-19165
    • Zadran, S.1    Remacle, F.2    Levine, R.D.3
  • 191
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: A potential marker for colorectal cancer screening
    • Ng EK, Chong WW, Jin H, Lam EK, Shin VY, Yu J, et al. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009; 58: 1375-81.
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.1    Chong, W.W.2    Jin, H.3    Lam, E.K.4    Shin, V.Y.5    Yu, J.6
  • 192
    • 52049121293 scopus 로고    scopus 로고
    • Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue
    • Wong TS, Liu XB, Wong BY, Ng RW, Yuen AP, Wei WI. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 2008; 14: 2588-92.
    • (2008) Clin Cancer Res , vol.14 , pp. 2588-2592
    • Wong, T.S.1    Liu, X.B.2    Wong, B.Y.3    Ng, R.W.4    Yuen, A.P.5    Wei, W.I.6
  • 193
    • 84864055685 scopus 로고    scopus 로고
    • Identification of suitable reference genes for qPCR analysis of serum microRNA in gastric cancer patients
    • Song J, Bai Z, Han W, Zhang J, Meng H, Bi J, et al. Identification of suitable reference genes for qPCR analysis of serum microRNA in gastric cancer patients. Dig Dis Sci 2012; 57: 897-904.
    • (2012) Dig Dis Sci , vol.57 , pp. 897-904
    • Song, J.1    Bai, Z.2    Han, W.3    Zhang, J.4    Meng, H.5    Bi, J.6
  • 194
    • 84892428615 scopus 로고    scopus 로고
    • Identification and validation of reference genes for qPCR detection of serum microRNAs in colorectal adenocarcinoma patients
    • Zheng G, Wang H, Zhang X, Yang Y, Wang L, Du L, et al. Identification and validation of reference genes for qPCR detection of serum microRNAs in colorectal adenocarcinoma patients. PLoS One 2013; 8: e83025.
    • (2013) PLoS One , vol.8 , pp. e83025
    • Zheng, G.1    Wang, H.2    Zhang, X.3    Yang, Y.4    Wang, L.5    Du, L.6
  • 195
    • 84922722600 scopus 로고    scopus 로고
    • Plasma microRNA-320, microRNA-let-7e and microRNA-21 as novel potential biomarkers for the detection of retinoblastoma
    • Liu SS, Wang YS, Sun YF, Miao LX, Wang J, Li YS, et al. Plasma microRNA-320, microRNA-let-7e and microRNA-21 as novel potential biomarkers for the detection of retinoblastoma. Biomed Rep 2014; 2: 424-8.
    • (2014) Biomed Rep , vol.2 , pp. 424-428
    • Liu, S.S.1    Wang, Y.S.2    Sun, Y.F.3    Miao, L.X.4    Wang, J.5    Li, Y.S.6
  • 196
    • 84908886551 scopus 로고    scopus 로고
    • Plasma microRNA profiles: Identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma
    • Komatsu S, Ichikawa D, Hirajima S, Kawaguchi T, Miyamae M, Okajima W, et al. Plasma microRNA profiles: identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma. Br J Cancer 2014; 111: 1614-24.
    • (2014) Br J Cancer , vol.111 , pp. 1614-1624
    • Komatsu, S.1    Ichikawa, D.2    Hirajima, S.3    Kawaguchi, T.4    Miyamae, M.5    Okajima, W.6
  • 197
    • 60849111385 scopus 로고    scopus 로고
    • Impact of normalization on miRNA microarray expression profiling
    • Pradervand S, Weber J, Thomas J, Bueno M, Wirapati P, Lefort K, et al. Impact of normalization on miRNA microarray expression profiling. RNA 2009; 15: 493-501.
    • (2009) RNA , vol.15 , pp. 493-501
    • Pradervand, S.1    Weber, J.2    Thomas, J.3    Bueno, M.4    Wirapati, P.5    Lefort, K.6


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