A blood-based biomarker panel for stratifying current risk for colorectal cancer

International Journal of Cancer

Volumn 126, Issue 5, 2010, Pages 1177-1186

  Marshall, Kenneth Wayne ^a   Mohr, Steve ^a   El Khettabi, Faysal ^a   Nossova, Nadejda ^a   Chao, Samuel ^a   Bao, Weisheng ^a   Ma, Jun ^a   Li, Xiao Jun ^a   Liew, Choong Chin ^a,b  

^a GeneNews Ltd   (Canada)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Biomarkers; Blood test; Colorectal cancer; Disease risk; Stratification

Indexed keywords

BIOLOGICAL MARKER;

ANXA3 GENE; ARTICLE; CANCER RISK; CANCER SCREENING; CLEC4D GENE; CLINICAL DECISION MAKING; COLORECTAL CANCER; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; IL2RB GENE; LMNB1 GENE; PREVALENCE; PRIORITY JOURNAL; PRRG4 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; TNFAIP6 GENE; VNN1 GENE;

AGED; AREA UNDER CURVE; COLORECTAL NEOPLASMS; EARLY DETECTION OF CANCER; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IN SITU HYBRIDIZATION; MALE; MASS SCREENING; MODELS, THEORETICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; ROC CURVE; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 74049087373     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24910     Document Type: Article

References (33)

1. American Cancer Society. Detailed guide: colon and rectum cancer. Atlanta: American Cancer Society, 2008. Available at: http://www.cancer.org/ docroot/CRI/CRI-2-3x.asp?dt=10. Accessed March 23, 2009.
2. Cancer Research UK. Bowel (colorectal cancer). Key facts on bowel cancer, 2008. Available at: http://info.cancerresearchuk.org/cancerstats/types/bowel/. Accessed March 23, 2009.
3. Stryker SJ, Wolff BG, Culp CE, Libbe SD, Ilstrup DM, MacCarty RL. Natural history of untreated colonic polyps. Gastroenterol 1987;92:1009-13.
4. O'Connell JB, Maggard M, Ko CY. Colon cancer survival rates with the new American Joint Committee on cancer sixth edition staging. J NCI 2004;96:1420-5.
5. US Preventive Services Task Force. Screening for colorectal cancer: recommendations and rationale. Ann Intern Med 2002;137:129-31.
6. Canadian Task Force on Preventive Health Care. Colorectal cancer screening: recommendation statement from the Canadian Task Force on Preventive Health Care. CMAJ 2001;165:206-8.
7. Robb KA, Miles A, Campbell J, Evans P, Wardle J. Can cancer risk information raise awareness without increasing anxiety? A randomized trial. Prev Med 2006;43:187-90.
8. Schwartz LM, Woloshin S, Fowler FJ, Welch HG. Enthusiasm for cancer screening in the United States. JAMA 2004;291:71-8.
9. US Department of Health and Human Services Centers for Disease Control and Prevention. Colorectal cancer test use among persons aged greater than or equal to 50 years - United States, 2001. MMWR 2003;52:193-6.
10. Zarychanski R, Chen Y, Bernstein CN, Hebert PC. Frequency of colorectal screening and the impact of family physicians on screening behaviour. CMAJ 2007;177:593-97.
11. American Cancer Society. Cancer prevention and early detection facts and figures. Atlanta: American Cancer Society, 2007.
12. Klabunde CN, Lanier D, Breslau ES, Zapka JG, Fletcher RH, Ransohoff DF, Winawer SJ. Improving colorectal cancer screening in primary care practice: innovative strategies and future directions. J Gen Int Med 2007;22:1195-205.
13. Levin TR, Zhao W, Conell C, Seeff LC, Manninen DL, Shapiro JA, Schulman J. Complications of colonoscopy in an integrated health care delivery system. Ann Intern Med 2006;145:880-6.
14. Liew CC, Ma J, Tang HC, Zheng R, Dempsey AA. Peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J Lab Clin Med 2006;147:126-32.
15. Burczynski ME. Transcriptional profiling of peripheral blood in oncology. In: Burczynski ME, Rockett JC, eds. Surrogate tissue analysis: genomic, proteomic and metabolomic approaches. Boca Raton, FL: Taylor and Francis, 2006.47-63.
16. Han M, Liew CT, Zhang HW, Chao S, Zheng R, Yip KT, Song ZY, Li HM, Geng XP, Zhu LX, Lin JJ, Marshall KW, et al. Novel, blood-based five-gene panel biomarker set for the detection of colorectal cancer. Clin Cancer Res 2008;14:455-60.
17. Imperiale TF, Ransohoff DF, Itzkowitz SH, Turnbull BA, Ross ME;Colorectal Cancer Study Group. Faecal DNA versus faecal occult blood for colorectal-cancer screening in an average-risk population. New Engl J Med 2004;351:2704-14.
18. Pharoah PDP, Antoniou AC, Easton DF, Ponder BAJ. Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 2008;358:2796-803.
19. Tibshirani R, A simple method for assessing sample sizes in microarray experiments. BMC Bioinformatics 2006;7:106.
20. Rozen S, Skaletsky H.Primer 3 on the WWW for general users and for biologist programmers. In: Krawetz S, Misener S, eds. Bioinformatics methods and protocols: methods in molecular biology. Totowa, NJ: Humana Press, 2000:365-86.
21. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001;25:402-8.
22. Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Richards WG, Jaklitsch MT, Sugarbaker DJ, Bueno R. Using gene expression ratios to predict outcome among patients with mesothelioma. J NCI 2003;95:598-605.
23. Hastie T, Tibshirani R, Friedman J. The elements of statistical learning: data mining, inference, and prediction. New York: Springer-Verlag, 2001.
24. Mann HB, Whitney DR. On a test of whether one of two random variables is stochastically larger than the other. Ann Math Stat 1947;18:50-60.
25. Duda RO, Hart PE, Stork DG. Pattern classification, 2nd edn. New York: Wiley, 2000.
26. Shapiro SS, Wilk MB. An analysis of variance test for normality (complete samples). Biometrika 1965;52:591-611.
27. Johns LE, Houlston RS. A systematic review and meta-analysis of familial colorectal cancer risk. Am J Gastroenterol 2001;96:2992-3003.
28. Butterworth AS, Higgins JP, Pharoah P. Relative and absolute risk of colorectal cancer for individuals with a family history: a meta-analysis. Eur J Cancer 2006;42:216-27.
29. Levin B, Lieberman DA, McFarland B, Smith RA, Brooks D, Andrews KS, Dash C, Giardiello FM, Glick S, Levin TR, Pickhardt P, Rex DK, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer and the American College of Radiology. CA cancer. J Clin 2008;58:130-60.
30. Mohr S, Liew CC. The peripheral blood transcriptome: new insights into disease and risk assessment. Trends Mol Med 2007;13:422-32.
31. Park JE, Lee DH, Lee JA, Park SG, Kim NS, Park BC, Cho S. Annexin A3 is a potential angiogenic mediator. Biochem Biophys Res Comm 2005;337:1283-7.
32. García-Tuñón I, Ricote M, Ruiz A, Fraile B, Paniagua R, Royuela M Interleukin-2 and its receptor complex (alpha, beta and gamma chains) in in situ and infiltrative human breast cancer: an immunohistochemical comparative study. Br Can Res 2004;6:R1-6.
33. Vijan S, Inadomi J, Hayward RA, Hofer TP, Fendrick AM. Projections of demand and capacity for colonoscopy related to increasing rates of colorectal cancer screening in the United States. Aliment Pharmacol Ther 2004;20:507-15.