메뉴 건너뛰기




Volumn 45, Issue 10, 2015, Pages 2798-2809

Type I IFN-mediated synergistic activation of mouse and human DC subsets by TLR agonists

Author keywords

Adjuvants; Dendritic cells; Synergy; Toll like receptors; Type I IFN

Indexed keywords

ALPHA INTERFERON; CD8ALPHA ANTIGEN; INTERFERON; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR AGONIST; MEMBRANE PROTEIN; TLR3 PROTEIN, HUMAN; TLR3 PROTEIN, MOUSE; TLR7 PROTEIN, HUMAN; TLR7 PROTEIN, MOUSE;

EID: 84943197766     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545583     Document Type: Article
Times cited : (18)

References (51)
  • 1
    • 0348135024 scopus 로고    scopus 로고
    • Dendritic-cell control of pathogen-driven T-cell polarization
    • Kapsenberg, M. L., Dendritic-cell control of pathogen-driven T-cell polarization. Nat. Rev. Immunol. 2003. 3: 984-993.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 984-993
    • Kapsenberg, M.L.1
  • 2
    • 5444274514 scopus 로고    scopus 로고
    • Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
    • Kawai, T., Sato, S., Ishii, K. J., Coban, C., Hemmi, H., Yamamoto, M., Terai, K. et al., Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat. Immunol. 2004. 5: 1061-1068.
    • (2004) Nat. Immunol. , vol.5 , pp. 1061-1068
    • Kawai, T.1    Sato, S.2    Ishii, K.J.3    Coban, C.4    Hemmi, H.5    Yamamoto, M.6    Terai, K.7
  • 3
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou, L., Holt, A. C., Medzhitov, R. and Flavell, R. A., Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001. 413: 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 4
    • 33845579097 scopus 로고    scopus 로고
    • Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides
    • Diebold, S. S., Massacrier, C., Akira, S., Paturel, C., Morel, Y. and Reis, e Sousa, Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides. Eur. J. Immunol. 2006. 36: 3256-3267.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 3256-3267
    • Diebold, S.S.1    Massacrier, C.2    Akira, S.3    Paturel, C.4    Morel, Y.5    Reis, E.S.6
  • 5
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • Hemmi, H., Kaisho, T., Takeuchi, O., Sato, S., Sanjo, H., Hoshino, K., Horiuchi, T. et al., Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat. Immunol. 2002. 3: 196-200.
    • (2002) Nat. Immunol. , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3    Sato, S.4    Sanjo, H.5    Hoshino, K.6    Horiuchi, T.7
  • 6
    • 0036088492 scopus 로고    scopus 로고
    • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
    • Jurk, M., Heil, F., Vollmer, J., Schetter, C., Krieg, A. M., Wagner, H., Lipford, G. et al., Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat. Immunol. 2002. 3: 499.
    • (2002) Nat. Immunol. , vol.3 , pp. 499
    • Jurk, M.1    Heil, F.2    Vollmer, J.3    Schetter, C.4    Krieg, A.M.5    Wagner, H.6    Lipford, G.7
  • 8
    • 0742272509 scopus 로고    scopus 로고
    • Toll-like receptors and dendritic cells: for whom the bug tolls
    • Reis, e Sousa, Toll-like receptors and dendritic cells: for whom the bug tolls. Semin. Immunol. 2004. 16: 27-34.
    • (2004) Semin. Immunol. , vol.16 , pp. 27-34
    • Reis, E.S.1
  • 9
    • 84902657598 scopus 로고    scopus 로고
    • Crosstalk between dendritic cell subsets and implications for dendritic cell-based anticancer immunotherapy
    • Bakdash, G., Schreurs, I., Schreibelt, G. and Tel, J., Crosstalk between dendritic cell subsets and implications for dendritic cell-based anticancer immunotherapy. Expert Rev. Clin. Immunol. 2014. 10: 915-926.
    • (2014) Expert Rev. Clin. Immunol. , vol.10 , pp. 915-926
    • Bakdash, G.1    Schreurs, I.2    Schreibelt, G.3    Tel, J.4
  • 10
    • 84873460701 scopus 로고    scopus 로고
    • Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients
    • Tel, J., Aarntzen, E. H., Baba, T., Schreibelt, G., Schulte, B. M., Benitez-Ribas, D., Boerman, O. C. et al., Natural human plasmacytoid dendritic cells induce antigen-specific T-cell responses in melanoma patients. Cancer Res. 2013. 73: 1063-1075.
    • (2013) Cancer Res , vol.73 , pp. 1063-1075
    • Tel, J.1    Aarntzen, E.H.2    Baba, T.3    Schreibelt, G.4    Schulte, B.M.5    Benitez-Ribas, D.6    Boerman, O.7
  • 11
    • 84863664792 scopus 로고    scopus 로고
    • Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity
    • Kreutz, M., Giquel, B., Hu, Q., Abuknesha, R., Uematsu, S., Akira, S., Nestle, F. O. et al., Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity. PLoS One 2012. 7: e40208.
    • (2012) PLoS One , vol.7 , pp. e40208
    • Kreutz, M.1    Giquel, B.2    Hu, Q.3    Abuknesha, R.4    Uematsu, S.5    Akira, S.6    Nestle, F.O.7
  • 13
    • 79952440284 scopus 로고    scopus 로고
    • Targeted antigen delivery and activation of dendritic cells in vivo: steps towards cost effective vaccines
    • Tacken, P. J. and Figdor, C. G., Targeted antigen delivery and activation of dendritic cells in vivo: steps towards cost effective vaccines. Semin. Immunol. 2011. 23: 12-20.
    • (2011) Semin. Immunol. , vol.23 , pp. 12-20
    • Tacken, P.J.1    Figdor, C.G.2
  • 14
    • 84879228653 scopus 로고    scopus 로고
    • Targeting dendritic cells-why bother?
    • Kreutz, M., Tacken, P. J. and Figdor, C. G., Targeting dendritic cells-why bother? Blood 2013. 121: 2836-2844.
    • (2013) Blood , vol.121 , pp. 2836-2844
    • Kreutz, M.1    Tacken, P.J.2    Figdor, C.G.3
  • 15
    • 23944489407 scopus 로고    scopus 로고
    • Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani, G., Rinaldi, A., Bertoni, F., Sallusto, F. and Lanzavecchia, A., Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 2005. 6: 769-776.
    • (2005) Nat. Immunol. , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 16
    • 18644364701 scopus 로고    scopus 로고
    • A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
    • Gautier, G., Humbert, M., Deauvieau, F., Scuiller, M., Hiscott, J., Bates, E. E., Trinchieri, G. et al., A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J. Exp. Med. 2005. 201: 1435-1446.
    • (2005) J. Exp. Med. , vol.201 , pp. 1435-1446
    • Gautier, G.1    Humbert, M.2    Deauvieau, F.3    Scuiller, M.4    Hiscott, J.5    Bates, E.E.6    Trinchieri, G.7
  • 18
    • 84855486511 scopus 로고    scopus 로고
    • Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
    • Caskey, M., Lefebvre, F., Filali-Mouhim, A., Cameron, M. J., Goulet, J. P., Haddad, E. K., Breton, G. et al., Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans. J. Exp. Med. 2011. 208: 2357-2366.
    • (2011) J. Exp. Med. , vol.208 , pp. 2357-2366
    • Caskey, M.1    Lefebvre, F.2    Filali-Mouhim, A.3    Cameron, M.J.4    Goulet, J.P.5    Haddad, E.K.6    Breton, G.7
  • 19
    • 0037738569 scopus 로고    scopus 로고
    • Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines
    • Edwards, A. D., Diebold, S. S., Slack, E. M., Tomizawa, H., Hemmi, H., Kaisho, T., Akira, S. et al., Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines. Eur. J. Immunol. 2003. 33: 827-833.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 827-833
    • Edwards, A.D.1    Diebold, S.S.2    Slack, E.M.3    Tomizawa, H.4    Hemmi, H.5    Kaisho, T.6    Akira, S.7
  • 20
    • 32944462834 scopus 로고    scopus 로고
    • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
    • Kanneganti, T. D., Ozoren, N., Body-Malapel, M., Amer, A., Park, J. H., Franchi, L., Whitfield, J. et al., Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006. 440: 233-236.
    • (2006) Nature , vol.440 , pp. 233-236
    • Kanneganti, T.D.1    Ozoren, N.2    Body-Malapel, M.3    Amer, A.4    Park, J.H.5    Franchi, L.6    Whitfield, J.7
  • 21
    • 78650614110 scopus 로고    scopus 로고
    • TLR ligands induce synergistic interferon-beta and interferon-lambda1 gene expression in human monocyte-derived dendritic cells
    • Makela, S. M., Osterlund, P. and Julkunen, I., TLR ligands induce synergistic interferon-beta and interferon-lambda1 gene expression in human monocyte-derived dendritic cells. Mol. Immunol. 2011. 48: 505-515.
    • (2011) Mol. Immunol. , vol.48 , pp. 505-515
    • Makela, S.M.1    Osterlund, P.2    Julkunen, I.3
  • 23
    • 68849105323 scopus 로고    scopus 로고
    • Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus
    • Thibault, D. L., Graham, K. L., Lee, L. Y., Balboni, I., Hertzog, P. J. and Utz, P. J., Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus. Arthritis Res. Ther. 2009. 11: R112.
    • (2009) Arthritis Res. Ther. , vol.11 , pp. R112
    • Thibault, D.L.1    Graham, K.L.2    Lee, L.Y.3    Balboni, I.4    Hertzog, P.J.5    Utz, P.J.6
  • 24
    • 0141886220 scopus 로고    scopus 로고
    • IFN-alpha skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities
    • Mohty, M., Vialle-Castellano, A., Nunes, J. A., Isnardon, D., Olive, D. and Gaugler, B., IFN-alpha skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities. J. Immunol. 2003. 171: 3385-3393.
    • (2003) J. Immunol. , vol.171 , pp. 3385-3393
    • Mohty, M.1    Vialle-Castellano, A.2    Nunes, J.A.3    Isnardon, D.4    Olive, D.5    Gaugler, B.6
  • 25
    • 84898669690 scopus 로고    scopus 로고
    • The closely related CD103+ dendritic cells (DCs) and lymphoid-resident CD8+ DCs differ in their inflammatory functions
    • Jiao, Z., Bedoui, S., Brady, J. L., Walter, A., Chopin, M., Carrington, E. M., Sutherland, R. M. et al., The closely related CD103+ dendritic cells (DCs) and lymphoid-resident CD8+ DCs differ in their inflammatory functions. PLoS One 2014. 9: e91126.
    • (2014) PLoS One , vol.9 , pp. e91126
    • Jiao, Z.1    Bedoui, S.2    Brady, J.L.3    Walter, A.4    Chopin, M.5    Carrington, E.M.6    Sutherland, R.M.7
  • 26
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway, C. A., Jr., Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 1989. 54 Pt 1: 1-13.
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.54 , pp. 1-13
    • Janeway, C.A.1
  • 27
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit, H., Kuhn, U., Muller, G., Steinbrink, K., Paragnik, L., Schmitt, E., Knop, J. et al., Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 1997. 27: 3135-3142.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3135-3142
    • Jonuleit, H.1    Kuhn, U.2    Muller, G.3    Steinbrink, K.4    Paragnik, L.5    Schmitt, E.6    Knop, J.7
  • 28
    • 66149186858 scopus 로고    scopus 로고
    • Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients
    • Bonehill, A., Van Nuffel, A. M., Corthals, J., Tuyaerts, S., Heirman, C., Francois, V., Colau, D. et al., Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients. Clin. Cancer Res. 2009. 15: 3366-3375.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3366-3375
    • Bonehill, A.1    Van Nuffel, A.M.2    Corthals, J.3    Tuyaerts, S.4    Heirman, C.5    Francois, V.6    Colau, D.7
  • 29
    • 58049209834 scopus 로고    scopus 로고
    • Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
    • Joffre, O., Nolte, M. A., Sporri, R. and Reis, e Sousa, Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol. Rev. 2009. 227: 234-247.
    • (2009) Immunol. Rev. , vol.227 , pp. 234-247
    • Joffre, O.1    Nolte, M.A.2    Sporri, R.3    Reis, E.S.4
  • 32
    • 2342648904 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells
    • Fonteneau, J. F., Larsson, M., Beignon, A. S., McKenna, K., Dasilva, I., Amara, A., Liu, Y. J. et al., Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells. J. Virol. 2004. 78: 5223-5232.
    • (2004) J. Virol. , vol.78 , pp. 5223-5232
    • Fonteneau, J.F.1    Larsson, M.2    Beignon, A.S.3    McKenna, K.4    Dasilva, I.5    Amara, A.6    Liu, Y.J.7
  • 34
    • 66149143133 scopus 로고    scopus 로고
    • Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation
    • Piccioli, D., Sammicheli, C., Tavarini, S., Nuti, S., Frigimelica, E., Manetti, A. G., Nuccitelli, A. et al., Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation. Blood 2009. 113: 4232-4239.
    • (2009) Blood , vol.113 , pp. 4232-4239
    • Piccioli, D.1    Sammicheli, C.2    Tavarini, S.3    Nuti, S.4    Frigimelica, E.5    Manetti, A.G.6    Nuccitelli, A.7
  • 35
    • 21244468609 scopus 로고    scopus 로고
    • CD8alpha+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo
    • Belz, G. T., Shortman, K., Bevan, M. J. and Heath, W. R., CD8alpha+ dendritic cells selectively present MHC class I-restricted noncytolytic viral and intracellular bacterial antigens in vivo. J. Immunol. 2005. 175: 196-200.
    • (2005) J. Immunol. , vol.175 , pp. 196-200
    • Belz, G.T.1    Shortman, K.2    Bevan, M.J.3    Heath, W.R.4
  • 36
    • 84872696776 scopus 로고    scopus 로고
    • TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8alpha+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface
    • Crespo, M. I., Zacca, E. R., Nunez, N. G., Ranocchia, R. P., Maccioni, M., Maletto, B. A., Pistoresi-Palencia, M. C. et al., TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8alpha+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface. J. Immunol. 2013. 190: 948-960.
    • (2013) J. Immunol. , vol.190 , pp. 948-960
    • Crespo, M.I.1    Zacca, E.R.2    Nunez, N.G.3    Ranocchia, R.P.4    Maccioni, M.5    Maletto, B.A.6    Pistoresi-Palencia, M.C.7
  • 37
    • 84880856650 scopus 로고    scopus 로고
    • The use of Toll-like receptor 7/8 agonists as vaccine adjuvants
    • Vasilakos, J. P. and Tomai, M. A., The use of Toll-like receptor 7/8 agonists as vaccine adjuvants. Expert Rev. Vaccines 2013. 12: 809-819.
    • (2013) Expert Rev. Vaccines , vol.12 , pp. 809-819
    • Vasilakos, J.P.1    Tomai, M.A.2
  • 38
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., Taira, K. et al., The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 2004. 5: 730-737.
    • (2004) Nat. Immunol. , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5    Miyagishi, M.6    Taira, K.7
  • 39
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
    • Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S. et al., Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006. 441: 101-105.
    • (2006) Nature , vol.441 , pp. 101-105
    • Kato, H.1    Takeuchi, O.2    Sato, S.3    Yoneyama, M.4    Yamamoto, M.5    Matsui, K.6    Uematsu, S.7
  • 40
    • 0035871737 scopus 로고    scopus 로고
    • Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells
    • Bauer, M., Redecke, V., Ellwart, J. W., Scherer, B., Kremer, J. P., Wagner, H. and Lipford, G. B., Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells. J. Immunol. 2001. 166: 5000-5007.
    • (2001) J. Immunol. , vol.166 , pp. 5000-5007
    • Bauer, M.1    Redecke, V.2    Ellwart, J.W.3    Scherer, B.4    Kremer, J.P.5    Wagner, H.6    Lipford, G.B.7
  • 41
    • 33645718864 scopus 로고    scopus 로고
    • In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells
    • Loseke, S., Grage-Griebenow, E., Heine, H., Wagner, A., Akira, S., Bauer, S. and Bufe, A., In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells. Scand. J. Immunol. 2006. 63: 264-274.
    • (2006) Scand. J. Immunol. , vol.63 , pp. 264-274
    • Loseke, S.1    Grage-Griebenow, E.2    Heine, H.3    Wagner, A.4    Akira, S.5    Bauer, S.6    Bufe, A.7
  • 42
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • Kadowaki, N., Ho, S., Antonenko, S., Malefyt, R. W., Kastelein, R. A., Bazan, F. and Liu, Y. J., Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med. 2001. 194: 863-869.
    • (2001) J. Exp. Med. , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefyt, R.W.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.J.7
  • 43
    • 0035179882 scopus 로고    scopus 로고
    • Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
    • Jarrossay, D., Napolitani, G., Colonna, M., Sallusto, F. and Lanzavecchia, A., Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur. J. Immunol. 2001. 31: 3388-3393.
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3388-3393
    • Jarrossay, D.1    Napolitani, G.2    Colonna, M.3    Sallusto, F.4    Lanzavecchia, A.5
  • 44
    • 77955557963 scopus 로고    scopus 로고
    • Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy
    • Schreibelt, G., Tel, J., Sliepen, K. H., Benitez-Ribas, D., Figdor, C. G., Adema, G. J. and de Vries, I. J., Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy. Cancer Immunol. Immunother. 2010. 59: 1573-1582.
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 1573-1582
    • Schreibelt, G.1    Tel, J.2    Sliepen, K.H.3    Benitez-Ribas, D.4    Figdor, C.G.5    Adema, G.J.6    de Vries, I.J.7
  • 45
    • 84867313947 scopus 로고    scopus 로고
    • IFN-alpha in the treatment of melanoma
    • Tarhini, A. A., Gogas, H. and Kirkwood, J. M., IFN-alpha in the treatment of melanoma. J. Immunol. 2012. 189: 3789-3793.
    • (2012) J. Immunol. , vol.189 , pp. 3789-3793
    • Tarhini, A.A.1    Gogas, H.2    Kirkwood, J.M.3
  • 46
    • 0021246077 scopus 로고
    • Interferons in the treatment of human cancer
    • Kirkwood, J. M. and Ernstoff, M. S., Interferons in the treatment of human cancer. J. Clin. Oncol. 1984. 2: 336-352.
    • (1984) J. Clin. Oncol. , vol.2 , pp. 336-352
    • Kirkwood, J.M.1    Ernstoff, M.S.2
  • 47
    • 77950576363 scopus 로고    scopus 로고
    • Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis
    • Mocellin, S., Pasquali, S., Rossi, C. R. and Nitti, D., Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis. J. Natl. Cancer Inst. 2010. 102: 493-501.
    • (2010) J. Natl. Cancer Inst. , vol.102 , pp. 493-501
    • Mocellin, S.1    Pasquali, S.2    Rossi, C.R.3    Nitti, D.4
  • 48
    • 79961160742 scopus 로고    scopus 로고
    • Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
    • Anandasabapathy, N., Victora, G. D., Meredith, M., Feder, R., Dong, B., Kluger, C., Yao, K. et al., Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. J. Exp. Med. 2011. 208: 1695-1705.
    • (2011) J. Exp. Med. , vol.208 , pp. 1695-1705
    • Anandasabapathy, N.1    Victora, G.D.2    Meredith, M.3    Feder, R.4    Dong, B.5    Kluger, C.6    Yao, K.7
  • 51
    • 85074914953 scopus 로고    scopus 로고
    • A PCR primer bank for quantitative gene expression analysis
    • Wang, X. and Seed, B., A PCR primer bank for quantitative gene expression analysis. Nucleic Acids Res. 2003. 31: e154.
    • (2003) Nucleic Acids Res , vol.31 , pp. e154
    • Wang, X.1    Seed, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.