Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 38, 2015, Pages 11858-11863

  Schmidt, Matthias ^a,b   Rohou, Alexis ^b,c   Lasker, Keren ^d   Yadav, Jay K ^a   Schiene Fischer, Cordelia ^e   Fändrich, Marcus ^a,b   Grigorieff, Nikolaus ^b,c   Petsko, Gregory A ^f  

^a UNIVERSITY OF ULM   (Germany)

^b BRANDEIS UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Cross ; Frealix; Protein aggregation; Protein folding

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN[1-42]; DIMER; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); IMMUNOGLOBULIN F(AB) FRAGMENT; PEPTIDE; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; CRYOELECTRON MICROSCOPY; HUMAN; MOLECULAR MODEL; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMISTRY; EPITOPE MAPPING; IMAGE PROCESSING; MOLECULAR GENETICS; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; AMYLOID; AMYLOID BETA-PEPTIDES; CRYOELECTRON MICROSCOPY; EPITOPE MAPPING; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOGLOBULIN FAB FRAGMENTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84942909501     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1503455112     Document Type: Article

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