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Volumn 13, Issue 1, 2015, Pages

Biomarkers and severe asthma: A critical appraisal

Author keywords

Allergic inflammation; Biomarkers; Eosinophil; Exhaled nitric oxide; Galectin; Monoclonal antibodies; Neutrophil; Periostin; Severe asthma

Indexed keywords

BIOLOGICAL MARKER; ECALECTIN; EOTAXIN; GALECTIN 3; INDUCIBLE NITRIC OXIDE SYNTHASE; LEUKOTRIENE B4; LIPOXIN A; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RUNX2;

EID: 84942770527     PISSN: None     EISSN: 14767961     Source Type: Journal    
DOI: 10.1186/s12948-015-0027-7     Document Type: Review
Times cited : (51)

References (143)
  • 1
    • 84893513577 scopus 로고    scopus 로고
    • International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
    • Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ et al (2014) International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J 43:343-373
    • (2014) Eur Respir J , vol.43 , pp. 343-373
    • Chung, K.F.1    Wenzel, S.E.2    Brozek, J.L.3    Bush, A.4    Castro, M.5    Sterk, P.J.6
  • 2
    • 0034526865 scopus 로고    scopus 로고
    • Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions
    • American Thoracic Society (2000) Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. Am J Respir Crit Care Med 162:2341-2351
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 2341-2351
  • 3
    • 33845987340 scopus 로고    scopus 로고
    • Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program
    • Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L et al (2007) Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 119:405-413
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 405-413
    • Moore, W.C.1    Bleecker, E.R.2    Curran-Everett, D.3    Erzurum, S.C.4    Ameredes, B.T.5    Bacharier, L.6
  • 4
    • 41549156474 scopus 로고    scopus 로고
    • Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma
    • Chen H, Blanc PD, Hayden ML, Bleecker ER, Chawla A, Lee JH et al (2008) Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma. Value Health 11:231-239
    • (2008) Value Health , vol.11 , pp. 231-239
    • Chen, H.1    Blanc, P.D.2    Hayden, M.L.3    Bleecker, E.R.4    Chawla, A.5    Lee, J.H.6
  • 5
    • 84860679595 scopus 로고    scopus 로고
    • Asthma phenotypes: the evolution from clinical to molecular approaches
    • Wenzel SE (2012) Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 18:716-725
    • (2012) Nat Med , vol.18 , pp. 716-725
    • Wenzel, S.E.1
  • 8
    • 76149146032 scopus 로고    scopus 로고
    • Identification of asthma phenotypes using cluster analysis in the severe asthma research program
    • Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X et al (2010) Identification of asthma phenotypes using cluster analysis in the severe asthma research program. Am J Respir Crit Care Med 181:315-323
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 315-323
    • Moore, W.C.1    Meyers, D.A.2    Wenzel, S.E.3    Teague, W.G.4    Li, H.5    Li, X.6
  • 10
    • 0034942124 scopus 로고    scopus 로고
    • Heterogeneity of airway inflammation in persistent asthma: evidence of neutrophilic inflammation and increased sputum interleukin-8
    • Gibson PG, Simpson JL, Saltos N (2001) Heterogeneity of airway inflammation in persistent asthma: evidence of neutrophilic inflammation and increased sputum interleukin-8. Chest 119:1329-1336
    • (2001) Chest , vol.119 , pp. 1329-1336
    • Gibson, P.G.1    Simpson, J.L.2    Saltos, N.3
  • 11
    • 84908278936 scopus 로고    scopus 로고
    • Repeatability of induced sputum measurements in moderate to severe asthma
    • Rossall MRW, Cadden PA, Molphy SD, Plumb J, Singh D (2014) Repeatability of induced sputum measurements in moderate to severe asthma. Respir Med 108:1566-1568
    • (2014) Respir Med , vol.108 , pp. 1566-1568
    • Rossall, M.R.W.1    Cadden, P.A.2    Molphy, S.D.3    Plumb, J.4    Singh, D.5
  • 12
    • 84862519263 scopus 로고    scopus 로고
    • Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial
    • Nair P, Gaga M, Zervas E, Alagha K, Hargreave FE, O'Byrne PM et al (2012) Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial. Clin Exp Allergy 42:1097-1103
    • (2012) Clin Exp Allergy , vol.42 , pp. 1097-1103
    • Nair, P.1    Gaga, M.2    Zervas, E.3    Alagha, K.4    Hargreave, F.E.5    O'Byrne, P.M.6
  • 13
    • 26944454482 scopus 로고    scopus 로고
    • Glucocorticoids suppress inflammation but spare innate immune responses in airway epithelium
    • Schleimer RP (2004) Glucocorticoids suppress inflammation but spare innate immune responses in airway epithelium. Proc Am Thorac Soc 1:222-230
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 222-230
    • Schleimer, R.P.1
  • 14
    • 65849427529 scopus 로고    scopus 로고
    • Glucocorticoid resistance in inflammatory diseases
    • Barnes PJ, Adcock IM (2009) Glucocorticoid resistance in inflammatory diseases. Lancet 373:1905-1917
    • (2009) Lancet , vol.373 , pp. 1905-1917
    • Barnes, P.J.1    Adcock, I.M.2
  • 16
    • 23644456321 scopus 로고    scopus 로고
    • ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation
    • Boldogh I, Bacsi A, Choudhury BK, Dharajiya N, Alam R, Hazra TK (2005) ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest 115:2169-2179
    • (2005) J Clin Invest , vol.115 , pp. 2169-2179
    • Boldogh, I.1    Bacsi, A.2    Choudhury, B.K.3    Dharajiya, N.4    Alam, R.5    Hazra, T.K.6
  • 17
    • 84942764582 scopus 로고    scopus 로고
    • Pollen-induced innate recruitment of neutrophils facilitates induction of allergic sensitization and airway inflammation
    • Hosoki K, Aguilera-Aguirre L, Brasier AR, Kurosky A, Boldogh I, Sur S (2015) Pollen-induced innate recruitment of neutrophils facilitates induction of allergic sensitization and airway inflammation. Am J Respir Cell Mol Biol. doi: 10.1165/rcmb.2015-0044OC
    • (2015) Am J Respir Cell Mol Biol
    • Hosoki, K.1    Aguilera-Aguirre, L.2    Brasier, A.R.3    Kurosky, A.4    Boldogh, I.5    Sur, S.6
  • 20
    • 34250181263 scopus 로고    scopus 로고
    • Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding
    • Gómez-Gaviro M, Domínguez-Luis M, Canchado J, Calafat J, Janssen H, Lara-Pezzi E et al (2007) Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding. J Immunol 178:8053-8063
    • (2007) J Immunol , vol.178 , pp. 8053-8063
    • Gómez-Gaviro, M.1    Domínguez-Luis, M.2    Canchado, J.3    Calafat, J.4    Janssen, H.5    Lara-Pezzi, E.6
  • 25
    • 85047693849 scopus 로고    scopus 로고
    • Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
    • Flood-Page P, Menzies-Gow A, Phipps S, Ying S, Wangoo A, Ludwig MS et al (2003) Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Investig 112:1029-1036
    • (2003) J Clin Investig , vol.112 , pp. 1029-1036
    • Flood-Page, P.1    Menzies-Gow, A.2    Phipps, S.3    Ying, S.4    Wangoo, A.5    Ludwig, M.S.6
  • 26
    • 0036795111 scopus 로고    scopus 로고
    • Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
    • Green RH, Brightling CE, Woltmann G, Parker D, Wardlaw AJ, Pavord ID (2002) Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax 57:875-879
    • (2002) Thorax , vol.57 , pp. 875-879
    • Green, R.H.1    Brightling, C.E.2    Woltmann, G.3    Parker, D.4    Wardlaw, A.J.5    Pavord, I.D.6
  • 27
    • 0346041503 scopus 로고    scopus 로고
    • Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation
    • Miranda C, Busacker A, Balzar S, Trudeau J, Wenzel SE (2004) Distinguishing severe asthma phenotypes: role of age at onset and eosinophilic inflammation. J Allergy Clin Immunol 113:101-108
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 101-108
    • Miranda, C.1    Busacker, A.2    Balzar, S.3    Trudeau, J.4    Wenzel, S.E.5
  • 28
    • 84930909640 scopus 로고    scopus 로고
    • What goes up must come down: biomarkers and novel biologicals in severe asthma
    • Hilvering B, Pavord ID (2015) What goes up must come down: biomarkers and novel biologicals in severe asthma. Clin Exp Allergy 45:1162-1169
    • (2015) Clin Exp Allergy , vol.45 , pp. 1162-1169
    • Hilvering, B.1    Pavord, I.D.2
  • 29
    • 0032875377 scopus 로고    scopus 로고
    • Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
    • Wenzel SE, Schwartz LB, Langmack EL, Halliday JL, Trudeau JB, Gibbs RL et al (1999) Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 160:1001-1008
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1001-1008
    • Wenzel, S.E.1    Schwartz, L.B.2    Langmack, E.L.3    Halliday, J.L.4    Trudeau, J.B.5    Gibbs, R.L.6
  • 31
    • 84863698582 scopus 로고    scopus 로고
    • Omalizumab modulates bronchial reticular basement membrane thickness and eosinophil infiltration in severe persistent allergic asthma patients
    • Riccio AM, Dal Negro RW, Micheletto C, De Ferrari L, Folli C, Chiappori A et al (2012) Omalizumab modulates bronchial reticular basement membrane thickness and eosinophil infiltration in severe persistent allergic asthma patients. Int J Immunopathol Pharmacol 25:475-484
    • (2012) Int J Immunopathol Pharmacol , vol.25 , pp. 475-484
    • Riccio, A.M.1    Dal Negro, R.W.2    Micheletto, C.3    Ferrari, L.4    Folli, C.5    Chiappori, A.6
  • 32
    • 78649331032 scopus 로고    scopus 로고
    • Anti-IgE therapy with omalizumab decreases endothelin-1 in exhaled breath condensate of patients with severe persistent allergic asthma
    • Zietkowski Z, Skiepko R, Tomasiak-Lozowska MM, Bodzenta-Lukaszyk A (2010) Anti-IgE therapy with omalizumab decreases endothelin-1 in exhaled breath condensate of patients with severe persistent allergic asthma. Respiration 80:534-542
    • (2010) Respiration , vol.80 , pp. 534-542
    • Zietkowski, Z.1    Skiepko, R.2    Tomasiak-Lozowska, M.M.3    Bodzenta-Lukaszyk, A.4
  • 35
    • 84908485601 scopus 로고    scopus 로고
    • Comprehensive efficacy of omalizumab for severe refractory asthma: a time-series observational study
    • Tajiri T, Niimi A, Matsumoto H, Ito I, Oguma T, Otsuka K et al (2014) Comprehensive efficacy of omalizumab for severe refractory asthma: a time-series observational study. Ann Allergy Asthma Immunol 113(470-5):e2
    • (2014) Ann Allergy Asthma Immunol , vol.113 , Issue.470-475 , pp. e2
    • Tajiri, T.1    Niimi, A.2    Matsumoto, H.3    Ito, I.4    Oguma, T.5    Otsuka, K.6
  • 36
    • 84925495840 scopus 로고    scopus 로고
    • The real-life clinical effects of 52 weeks of omalizumab therapy for severe persistent allergic asthma
    • Gouder C, West LM, Montefort S (2015) The real-life clinical effects of 52 weeks of omalizumab therapy for severe persistent allergic asthma. Int J Clin Pharm 37:36-43
    • (2015) Int J Clin Pharm , vol.37 , pp. 36-43
    • Gouder, C.1    West, L.M.2    Montefort, S.3
  • 37
    • 84908278609 scopus 로고    scopus 로고
    • Proteomics of bronchial biopsies: galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients
    • Mauri P, Riccio AM, Rossi R, DiSilvestre D, Benazzi L, DeFerrari L et al (2014) Proteomics of bronchial biopsies: galectin-3 as a predictive biomarker of airway remodelling modulation in omalizumab-treated severe asthma patients. Immunol Lett 162(1 Pt A):2-10
    • (2014) Immunol Lett , vol.162 , Issue.1 , pp. 2-10
    • Mauri, P.1    Riccio, A.M.2    Rossi, R.3    DiSilvestre, D.4    Benazzi, L.5    DeFerrari, L.6
  • 38
    • 84858322573 scopus 로고    scopus 로고
    • Clinical update on the use of biomarkers of airway inflammation in the management of asthma
    • Wadsworth S, Sin D, Dorscheid D (2011) Clinical update on the use of biomarkers of airway inflammation in the management of asthma. J Asthma Allergy 4:77-86
    • (2011) J Asthma Allergy , vol.4 , pp. 77-86
    • Wadsworth, S.1    Sin, D.2    Dorscheid, D.3
  • 39
    • 84873136114 scopus 로고    scopus 로고
    • Eosinophils as diagnostic tools in chronic lung disease
    • Eltboli O, Brightling CE (2013) Eosinophils as diagnostic tools in chronic lung disease. Expert Rev Respir Med 7:33-42
    • (2013) Expert Rev Respir Med , vol.7 , pp. 33-42
    • Eltboli, O.1    Brightling, C.E.2
  • 41
    • 84905562745 scopus 로고    scopus 로고
    • Lung function decline and variable airway inflammatory pattern: longitudinal analysis of severe asthma
    • Newby C, Agbetile J, Hargadon B, Monteiro W, Green R, Pavord I et al (2014) Lung function decline and variable airway inflammatory pattern: longitudinal analysis of severe asthma. J Allergy Clin Immunol 134:287-294
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 287-294
    • Newby, C.1    Agbetile, J.2    Hargadon, B.3    Monteiro, W.4    Green, R.5    Pavord, I.6
  • 43
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial
    • Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON et al (2012) Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 380:651-659
    • (2012) Lancet , vol.380 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3    Bleecker, E.R.4    Buhl, R.5    Keene, O.N.6
  • 44
    • 84884905728 scopus 로고    scopus 로고
    • Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects
    • Malinovschi A, Fonseca JA, Jacinto T, Alving K, Janson C (2013) Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects. J Allergy Clin Immunol 132:821-827
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 821-827
    • Malinovschi, A.1    Fonseca, J.A.2    Jacinto, T.3    Alving, K.4    Janson, C.5
  • 45
    • 84903608027 scopus 로고    scopus 로고
    • Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma
    • Katz LE, Gleich GJ, Hartley BF, Yancey SW, Ortega HG (2014) Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma. Ann Am Thorac Soc 11:531-536
    • (2014) Ann Am Thorac Soc , vol.11 , pp. 531-536
    • Katz, L.E.1    Gleich, G.J.2    Hartley, B.F.3    Yancey, S.W.4    Ortega, H.G.5
  • 46
    • 4444232912 scopus 로고    scopus 로고
    • Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma
    • Djukanović R, Wilson SJ, Kraft M, Jarjour NN, Steel M, Chung KF et al (2004) Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med 170:583-593
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 583-593
    • Djukanović, R.1    Wilson, S.J.2    Kraft, M.3    Jarjour, N.N.4    Steel, M.5    Chung, K.F.6
  • 47
    • 84876883293 scopus 로고    scopus 로고
    • Exploring the effects of Omalizumab in allergic asthma. An analysis of biomarkers in the EXTRA study
    • Hanania NA, Wenzel S, Rosen K, Hsieh HJ, Mosesova S, Choy DF et al (2013) Exploring the effects of Omalizumab in allergic asthma. An analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med 187:804-811
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 804-811
    • Hanania, N.A.1    Wenzel, S.2    Rosen, K.3    Hsieh, H.J.4    Mosesova, S.5    Choy, D.F.6
  • 48
    • 0035719959 scopus 로고    scopus 로고
    • Eotaxin and the attraction of eosinophils to the asthmatic lung
    • Conroy DM, Williams TJ (2001) Eotaxin and the attraction of eosinophils to the asthmatic lung. Respir Res 2:150-156
    • (2001) Respir Res , vol.2 , pp. 150-156
    • Conroy, D.M.1    Williams, T.J.2
  • 50
    • 79952452965 scopus 로고    scopus 로고
    • The roles of a Th2 cytokine and CC chemokine in children with stable asthma: potential implication in eosinophil degranulation
    • Kim CK, Kita H, Callaway Z, Kim HB, Choi J, Fujisawa T et al (2010) The roles of a Th2 cytokine and CC chemokine in children with stable asthma: potential implication in eosinophil degranulation. Pediatr Allergy Immunol 21:e697-e704
    • (2010) Pediatr Allergy Immunol , vol.21 , pp. e697-e704
    • Kim, C.K.1    Kita, H.2    Callaway, Z.3    Kim, H.B.4    Choi, J.5    Fujisawa, T.6
  • 51
    • 84907174946 scopus 로고    scopus 로고
    • CCL-11 as a potential diagnostic marker for asthma?
    • Wu D, Zhou J, Bi H, Li L, Gao W, Huang M et al (2014) CCL-11 as a potential diagnostic marker for asthma? J Asthma 51:847-854
    • (2014) J Asthma , vol.51 , pp. 847-854
    • Wu, D.1    Zhou, J.2    Bi, H.3    Li, L.4    Gao, W.5    Huang, M.6
  • 53
    • 84872723771 scopus 로고    scopus 로고
    • TGF-ß2 decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cell
    • Harrop CA, Gore RB, Evans CM, Thornton DJ, Herrick SE (2013) TGF-ß2 decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cell. Exp Lung Res 39:39-47
    • (2013) Exp Lung Res , vol.39 , pp. 39-47
    • Harrop, C.A.1    Gore, R.B.2    Evans, C.M.3    Thornton, D.J.4    Herrick, S.E.5
  • 54
    • 84908263310 scopus 로고    scopus 로고
    • Transforming growth factor ß and severe asthma: a perfect storm
    • Al-Alawi M, Hassan T, Chotirmall SH (2014) Transforming growth factor ß and severe asthma: a perfect storm. Respir Med 108:1409-1423
    • (2014) Respir Med , vol.108 , pp. 1409-1423
    • Al-Alawi, M.1    Hassan, T.2    Chotirmall, S.H.3
  • 55
    • 4544317836 scopus 로고    scopus 로고
    • Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath
    • Lane C, Knight D, Burgess S, Franklin P, Horak F, Legg J et al (2004) Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath. Thorax 59:757-760
    • (2004) Thorax , vol.59 , pp. 757-760
    • Lane, C.1    Knight, D.2    Burgess, S.3    Franklin, P.4    Horak, F.5    Legg, J.6
  • 57
    • 80052438246 scopus 로고    scopus 로고
    • on behalf of the American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications. An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications
    • Dweik RA, Boggs PB, Erzurum SC, Irvin CG, Leigh MW, Lundberg JO et al (2011) on behalf of the American Thoracic Society Committee on Interpretation of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications. An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications. Am J Respir Crit Care Med 184:602-615
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 602-615
    • Dweik, R.A.1    Boggs, P.B.2    Erzurum, S.C.3    Irvin, C.G.4    Leigh, M.W.5    Lundberg, J.O.6
  • 58
    • 84942806911 scopus 로고    scopus 로고
    • Association of longitudinal fractional exhaled nitric oxide measurements with asthma control in atopic children
    • Yang S, Park J, Lee YK, Kim H, Hahn YS (2015) Association of longitudinal fractional exhaled nitric oxide measurements with asthma control in atopic children. Respir Med 109:572-579
    • (2015) Respir Med , vol.109 , pp. 572-579
    • Yang, S.1    Park, J.2    Lee, Y.K.3    Kim, H.4    Hahn, Y.S.5
  • 59
    • 84964525929 scopus 로고    scopus 로고
    • Fractional exhaled nitric oxide (FeNo) in different asthma phenotypes
    • Gemicioglu B, Musellim B, Dogan I, Guven K (2014) Fractional exhaled nitric oxide (FeNo) in different asthma phenotypes. Allergy Rhinol 5:157-161
    • (2014) Allergy Rhinol , vol.5 , pp. 157-161
    • Gemicioglu, B.1    Musellim, B.2    Dogan, I.3    Guven, K.4
  • 66
    • 0037323904 scopus 로고    scopus 로고
    • Gross pathology and hystopatology of asthma
    • Hamid Q (2003) Gross pathology and hystopatology of asthma. J Allergy Clin Immunol 111:431-432
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 431-432
    • Hamid, Q.1
  • 67
  • 68
    • 24644515785 scopus 로고    scopus 로고
    • ATS/ERS Task Force on Exhaled Breath Condensate. Exhaled breath condensate: methodological recommendations and unresolved questions
    • Horváth I, Hunt J, Barnes PJ, Alving K, Antczak A, Baraldi E et al (2005) ATS/ERS Task Force on Exhaled Breath Condensate. Exhaled breath condensate: methodological recommendations and unresolved questions. Eur Respir J 26:523-548
    • (2005) Eur Respir J , vol.26 , pp. 523-548
    • Horváth, I.1    Hunt, J.2    Barnes, P.J.3    Alving, K.4    Antczak, A.5    Baraldi, E.6
  • 69
    • 84928589239 scopus 로고    scopus 로고
    • Increased of exhaled breath condensate neutrophil chemotaxis in acute exacerbation of COPD
    • Corhay JL, Moermans C, Henket M, Nguyen Dang D, Duysinx B, Louis R (2014) Increased of exhaled breath condensate neutrophil chemotaxis in acute exacerbation of COPD. Respir Res 15:115
    • (2014) Respir Res , vol.15 , pp. 115
    • Corhay, J.L.1    Moermans, C.2    Henket, M.3    Nguyen Dang, D.4    Duysinx, B.5    Louis, R.6
  • 71
    • 77954740897 scopus 로고    scopus 로고
    • Exhaled nitric oxide and exhaled breath condensate pH in severe refractory asthma
    • Tseliou E, Bessa V, Hillas G, Delimpoura V, Papadaki G, Roussos C et al (2010) Exhaled nitric oxide and exhaled breath condensate pH in severe refractory asthma. Chest 138:107-113
    • (2010) Chest , vol.138 , pp. 107-113
    • Tseliou, E.1    Bessa, V.2    Hillas, G.3    Delimpoura, V.4    Papadaki, G.5    Roussos, C.6
  • 72
    • 79551574730 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP). Determinants of exhaled breath condensate pH in a large population with asthma
    • Liu L, Teague WG, Erzurum S, Fitzpatrick A, Mantri S, Dweik RA et al (2011) National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP). Determinants of exhaled breath condensate pH in a large population with asthma. Chest 139:328-336
    • (2011) Chest , vol.139 , pp. 328-336
    • Liu, L.1    Teague, W.G.2    Erzurum, S.3    Fitzpatrick, A.4    Mantri, S.5    Dweik, R.A.6
  • 74
    • 71549136876 scopus 로고    scopus 로고
    • Redox control of asthma: molecular mechanisms and therapeutic opportunities
    • Comhair SA, Erzurum SC (2010) Redox control of asthma: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal 12:93-124
    • (2010) Antioxid Redox Signal , vol.12 , pp. 93-124
    • Comhair, S.A.1    Erzurum, S.C.2
  • 76
    • 83555172342 scopus 로고    scopus 로고
    • Metabolomics applied to urine samples in childhood asthma; differentiation between asthma phenotypes and identification of relevant metabolites
    • Mattarucchi E, Baraldi E, Guillou C (2012) Metabolomics applied to urine samples in childhood asthma; differentiation between asthma phenotypes and identification of relevant metabolites. Biomed Chromatogr 26:89-94
    • (2012) Biomed Chromatogr , vol.26 , pp. 89-94
    • Mattarucchi, E.1    Baraldi, E.2    Guillou, C.3
  • 77
    • 84868709084 scopus 로고    scopus 로고
    • Online trapping and enrichment ultra performance liquid chromatography-tandem mass spectrometry method for sensitive measurement of "arginine-asymmetric dimethylarginine cycle" biomarkers in human exhaled breath condensate
    • Di Gangi IM, Pirillo P, Carraro S, Gucciardi A, Naturale M, Baraldi E et al (2012) Online trapping and enrichment ultra performance liquid chromatography-tandem mass spectrometry method for sensitive measurement of "arginine-asymmetric dimethylarginine cycle" biomarkers in human exhaled breath condensate. Anal Chim Acta 754:67-74
    • (2012) Anal Chim Acta , vol.754 , pp. 67-74
    • Gangi, I.M.1    Pirillo, P.2    Carraro, S.3    Gucciardi, A.4    Naturale, M.5    Baraldi, E.6
  • 78
    • 84870625146 scopus 로고    scopus 로고
    • Asthma severity in childhood and metabolomic profiling of breath condensate
    • Carraro S, Giordano G, Reniero F, Carpi D, Stocchero M, Sterk PJ et al (2013) Asthma severity in childhood and metabolomic profiling of breath condensate. Allergy 68:110-117
    • (2013) Allergy , vol.68 , pp. 110-117
    • Carraro, S.1    Giordano, G.2    Reniero, F.3    Carpi, D.4    Stocchero, M.5    Sterk, P.J.6
  • 80
    • 84891682499 scopus 로고    scopus 로고
    • Children with severe asthma have unique oxidative stress-associated metabolomic profiles
    • Fitzpatrick AM, Park Y, Brown LA, Jones DP (2014) Children with severe asthma have unique oxidative stress-associated metabolomic profiles. J Allergy Clin Immunol 133:258-261
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 258-261
    • Fitzpatrick, A.M.1    Park, Y.2    Brown, L.A.3    Jones, D.P.4
  • 82
    • 33745394558 scopus 로고    scopus 로고
    • Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals
    • Takayama G, Arima K, Kanaji T, Toda S, Tanaka H, Shoji S et al (2006) Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals. J Allergy Clin Immunol 118:98-104
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 98-104
    • Takayama, G.1    Arima, K.2    Kanaji, T.3    Toda, S.4    Tanaka, H.5    Shoji, S.6
  • 85
    • 77956289251 scopus 로고    scopus 로고
    • Roles of epithelial cell-derived periostin in TFG-beta activation, collagen production, and collagen gel elasticity in asthma
    • Sidhu SS, Yuan S, Innes AL, Kerr S, Woodruff PG, Hou L et al (2010) Roles of epithelial cell-derived periostin in TFG-beta activation, collagen production, and collagen gel elasticity in asthma. Proc Natl Acad Sci USA 107:14170-14175
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14170-14175
    • Sidhu, S.S.1    Yuan, S.2    Innes, A.L.3    Kerr, S.4    Woodruff, P.G.5    Hou, L.6
  • 86
  • 87
    • 84863539707 scopus 로고    scopus 로고
    • Periostin promotes chronic allergic inflammation in response to Th2 cytokines
    • Masuoka M, Shiraishi H, Ohta S, Suzuki S, Arima K, Aoki S et al (2012) Periostin promotes chronic allergic inflammation in response to Th2 cytokines. J Clin Invest 122:2590-2600
    • (2012) J Clin Invest , vol.122 , pp. 2590-2600
    • Masuoka, M.1    Shiraishi, H.2    Ohta, S.3    Suzuki, S.4    Arima, K.5    Aoki, S.6
  • 88
    • 84901986444 scopus 로고    scopus 로고
    • Serum periostin: a novel biomarker for asthma management
    • Matsumoto H (2014) Serum periostin: a novel biomarker for asthma management. Allergol Int 63:153-160
    • (2014) Allergol Int , vol.63 , pp. 153-160
    • Matsumoto, H.1
  • 90
    • 84881180798 scopus 로고    scopus 로고
    • Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids
    • Kanemitsu Y, Matsumoto H, Izuhara K, Tohda Y, Kita H, Horiguchi T et al (2013) Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. J Allergy Clin Immunol 132:305-312
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 305-312
    • Kanemitsu, Y.1    Matsumoto, H.2    Izuhara, K.3    Tohda, Y.4    Kita, H.5    Horiguchi, T.6
  • 94
    • 85027957024 scopus 로고    scopus 로고
    • Periostin levels correlate with disease severity and chronicity in patients with atopic dermatitis
    • Kou K, Okawa T, Yamaguchi Y, Ono J, Inoue Y, Kohno M et al (2014) Periostin levels correlate with disease severity and chronicity in patients with atopic dermatitis. Br J Dermatol 171:283-291
    • (2014) Br J Dermatol , vol.171 , pp. 283-291
    • Kou, K.1    Okawa, T.2    Yamaguchi, Y.3    Ono, J.4    Inoue, Y.5    Kohno, M.6
  • 95
    • 84857449755 scopus 로고    scopus 로고
    • Clinical and pathological characteristics of IgG4-related sclerosing sialadenitis
    • Ohta N, Kurakami K, Ishida A, Furukawa T, Saito F, Kakehata S et al (2012) Clinical and pathological characteristics of IgG4-related sclerosing sialadenitis. Laryngoscope 122:572-577
    • (2012) Laryngoscope , vol.122 , pp. 572-577
    • Ohta, N.1    Kurakami, K.2    Ishida, A.3    Furukawa, T.4    Saito, F.5    Kakehata, S.6
  • 96
    • 84871512983 scopus 로고    scopus 로고
    • Expression of pendrin and periostin in allergic rhinitis and chronic rhinosinusitis
    • Ishida A, Ohta N, Suzuki Y, Kakehata S, Okubo K, Ikeda H et al (2012) Expression of pendrin and periostin in allergic rhinitis and chronic rhinosinusitis. Allergol Int 61:589-595
    • (2012) Allergol Int , vol.61 , pp. 589-595
    • Ishida, A.1    Ohta, N.2    Suzuki, Y.3    Kakehata, S.4    Okubo, K.5    Ikeda, H.6
  • 98
    • 79955674250 scopus 로고    scopus 로고
    • Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias
    • Okamoto M, Hoshino T, Kitasato Y, Sakazaki Y, Kawayama T, Fujimoto K et al (2011) Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias. Eur Respir J 37:1119-1127
    • (2011) Eur Respir J , vol.37 , pp. 1119-1127
    • Okamoto, M.1    Hoshino, T.2    Kitasato, Y.3    Sakazaki, Y.4    Kawayama, T.5    Fujimoto, K.6
  • 99
    • 84860504942 scopus 로고    scopus 로고
    • Periostin, a matricellular protein, plays a role in the induction of chemokines in pulmonary fibrosis
    • Uchida M, Shiraishi H, Ohta S, Arima K, Taniguchi K, Suzuki S et al (2012) Periostin, a matricellular protein, plays a role in the induction of chemokines in pulmonary fibrosis. Am J Respir Cell Mol Biol 46:677-686
    • (2012) Am J Respir Cell Mol Biol , vol.46 , pp. 677-686
    • Uchida, M.1    Shiraishi, H.2    Ohta, S.3    Arima, K.4    Taniguchi, K.5    Suzuki, S.6
  • 100
    • 43549118588 scopus 로고    scopus 로고
    • Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma
    • Stankovic KM, Goldsztein H, Reh DD, Platt MP, Metson R (2008) Gene expression profiling of nasal polyps associated with chronic sinusitis and aspirin-sensitive asthma. Laryngoscope 118:881-889
    • (2008) Laryngoscope , vol.118 , pp. 881-889
    • Stankovic, K.M.1    Goldsztein, H.2    Reh, D.D.3    Platt, M.P.4    Metson, R.5
  • 101
    • 79953058276 scopus 로고    scopus 로고
    • Periostin, a matrix protein, has potential as a novel serodiagnostic marker for cholangiocarcinoma
    • Fujimoto K, Kawaguchi T, Nakashima O, Ono J, Kawaguchi A, Tonan T et al (2011) Periostin, a matrix protein, has potential as a novel serodiagnostic marker for cholangiocarcinoma. Oncol Rep 25:1211-1216
    • (2011) Oncol Rep , vol.25 , pp. 1211-1216
    • Fujimoto, K.1    Kawaguchi, T.2    Nakashima, O.3    Ono, J.4    Kawaguchi, A.5    Tonan, T.6
  • 102
    • 84909995740 scopus 로고    scopus 로고
    • Periostin in intrahepatic cholangiocarcinoma: pathobiological insights and clinical implications
    • Sirica AE, Almenara JA, Li C (2014) Periostin in intrahepatic cholangiocarcinoma: pathobiological insights and clinical implications. Exp Mol Pathol 97:515-524
    • (2014) Exp Mol Pathol , vol.97 , pp. 515-524
    • Sirica, A.E.1    Almenara, J.A.2    Li, C.3
  • 104
    • 84941964822 scopus 로고    scopus 로고
    • Up-regulation of periostin and reactive stroma is associated with primary chemoresistance and predicts clinical outcomes in epithelial ovarian cancer.
    • pii: clincanres.3111.2014
    • Ryner L, Guan Y, Firestein R, Xiao Y, Choi Y, Rabe C et al (2015) Up-regulation of periostin and reactive stroma is associated with primary chemoresistance and predicts clinical outcomes in epithelial ovarian cancer. Clin Cancer Res. pii: clincanres.3111.2014
    • (2015) Clin Cancer Res.
    • Ryner, L.1    Guan, Y.2    Firestein, R.3    Xiao, Y.4    Choi, Y.5    Rabe, C.6
  • 105
    • 84931568591 scopus 로고    scopus 로고
    • Periostin induces chemoresistance in colon cancer cells through activation of the PI3 K/Akt/survivin pathway
    • Xiao ZM, Wang XY, Wang AM (2013) Periostin induces chemoresistance in colon cancer cells through activation of the PI3 K/Akt/survivin pathway. Biotechnol Appl Biochem. doi: 10.1002/bab.1193
    • (2013) Biotechnol Appl Biochem
    • Xiao, Z.M.1    Wang, X.Y.2    Wang, A.M.3
  • 106
    • 34247236139 scopus 로고    scopus 로고
    • Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity
    • Erkan M, Kleeff J, Gorbachevski A, Reiser C, Mitkus T, Esposito I et al (2007) Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 132:1447-1464
    • (2007) Gastroenterology , vol.132 , pp. 1447-1464
    • Erkan, M.1    Kleeff, J.2    Gorbachevski, A.3    Reiser, C.4    Mitkus, T.5    Esposito, I.6
  • 107
    • 34047093817 scopus 로고    scopus 로고
    • Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway
    • Baril P, Gangeswaran R, Mahon PC, Caulee K, Kocher HM, Harada T et al (2007) Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene 26:2082-2094
    • (2007) Oncogene , vol.26 , pp. 2082-2094
    • Baril, P.1    Gangeswaran, R.2    Mahon, P.C.3    Caulee, K.4    Kocher, H.M.5    Harada, T.6
  • 108
    • 84902551497 scopus 로고    scopus 로고
    • Periostin accelerates human malignant melanoma progression by modifying the melanoma microenviroment
    • Kotobuki Y, Yang L, Serada S, Tanemura A, Yang F, Nomura S et al (2014) Periostin accelerates human malignant melanoma progression by modifying the melanoma microenviroment. Pigment Cell Melanoma Res 27:630-639
    • (2014) Pigment Cell Melanoma Res , vol.27 , pp. 630-639
    • Kotobuki, Y.1    Yang, L.2    Serada, S.3    Tanemura, A.4    Yang, F.5    Nomura, S.6
  • 109
    • 84865597654 scopus 로고    scopus 로고
    • Periostin directly and indirectly promotes tumor lymphangiogenesis of head and neck cancer
    • Kudo Y, Iizuka S, Yoshida M, Nguyen PT, Siriwardena SB, Tsunematsu T et al (2012) Periostin directly and indirectly promotes tumor lymphangiogenesis of head and neck cancer. PLoS One. doi: 10.1371/journal.pone.0044488
    • (2012) PLoS One
    • Kudo, Y.1    Iizuka, S.2    Yoshida, M.3    Nguyen, P.T.4    Siriwardena, S.B.5    Tsunematsu, T.6
  • 110
    • 84923068676 scopus 로고    scopus 로고
    • Periostin secreted by glioblastoma stem cells recruits M2 tumor-associated macrophage and promotes malignant growth
    • Zhou W, Ke SQ, Huang Z, Flavahan W, Fang X, Paul J et al (2015) Periostin secreted by glioblastoma stem cells recruits M2 tumor-associated macrophage and promotes malignant growth. Nat Cell Biol 17:170-182
    • (2015) Nat Cell Biol , vol.17 , pp. 170-182
    • Zhou, W.1    Ke, S.Q.2    Huang, Z.3    Flavahan, W.4    Fang, X.5    Paul, J.6
  • 111
    • 84867312244 scopus 로고    scopus 로고
    • Cancer stem cell-related gene periostin: a novel prognostic marker for breast cancer
    • Xu D, Xu H, Ren Y, Liu C, Wang X, Zhang H et al (2012) Cancer stem cell-related gene periostin: a novel prognostic marker for breast cancer. PLoS One 7:e46670
    • (2012) PLoS One , vol.7 , pp. e46670
    • Xu, D.1    Xu, H.2    Ren, Y.3    Liu, C.4    Wang, X.5    Zhang, H.6
  • 112
    • 58149385884 scopus 로고    scopus 로고
    • Expression of periostin in patients with non-small cell lung cancer: correlation with angiogenesis and lymphangiogenesis
    • Takanami I, Abiko T, Koizumi S (2008) Expression of periostin in patients with non-small cell lung cancer: correlation with angiogenesis and lymphangiogenesis. Int J Biol Markers 23:182-186
    • (2008) Int J Biol Markers , vol.23 , pp. 182-186
    • Takanami, I.1    Abiko, T.2    Koizumi, S.3
  • 114
    • 58149119816 scopus 로고    scopus 로고
    • Periostin, a novel marker of intramembranous ossification, is expressed in fibrous dysplasia and in c-Fos-overexpressing bone lesions
    • Kashima TG, Nishiyama T, Shimazu K, Shimazaki M, Kii I, Grigoriadis AE et al (2009) Periostin, a novel marker of intramembranous ossification, is expressed in fibrous dysplasia and in c-Fos-overexpressing bone lesions. Hum Pathol 40:226-237
    • (2009) Hum Pathol , vol.40 , pp. 226-237
    • Kashima, T.G.1    Nishiyama, T.2    Shimazu, K.3    Shimazaki, M.4    Kii, I.5    Grigoriadis, A.E.6
  • 115
    • 84875414434 scopus 로고    scopus 로고
    • Serum periostin levels are correlated with progressive skin sclerosis on patients with systemic sclerosis
    • Yamaguchi Y, Ono J, Masuoka M, Ohtta S, Izuhara K, Ikezawa Z et al (2013) Serum periostin levels are correlated with progressive skin sclerosis on patients with systemic sclerosis. Br J Dermatol 168:717-725
    • (2013) Br J Dermatol , vol.168 , pp. 717-725
    • Yamaguchi, Y.1    Ono, J.2    Masuoka, M.3    Ohtta, S.4    Izuhara, K.5    Ikezawa, Z.6
  • 116
    • 84894562099 scopus 로고    scopus 로고
    • Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy
    • Ishikawa K, Yoshida S, Nakao S, Nakama T, Kita T, Asato R et al (2014) Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy. FASEB J 28:131-142
    • (2014) FASEB J , vol.28 , pp. 131-142
    • Ishikawa, K.1    Yoshida, S.2    Nakao, S.3    Nakama, T.4    Kita, T.5    Asato, R.6
  • 117
    • 84942809186 scopus 로고    scopus 로고
    • Periostin contributes to epidermal hyperplasia in psoriasis common to atopic dermatitis
    • Arima K, Ohta S, Takagi A, Shiraishi H, Masuoka M, Ontsuka K et al (2015) Periostin contributes to epidermal hyperplasia in psoriasis common to atopic dermatitis. Allergol Int 64:41-48
    • (2015) Allergol Int , vol.64 , pp. 41-48
    • Arima, K.1    Ohta, S.2    Takagi, A.3    Shiraishi, H.4    Masuoka, M.5    Ontsuka, K.6
  • 118
    • 80053223059 scopus 로고    scopus 로고
    • Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis
    • Sen K, Lindermeyer MT, Gaspert A, Eichinger F, Neusser MA, Kretzler M et al (2011) Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis. Am J Pathol 179:1756-1767
    • (2011) Am J Pathol , vol.179 , pp. 1756-1767
    • Sen, K.1    Lindermeyer, M.T.2    Gaspert, A.3    Eichinger, F.4    Neusser, M.A.5    Kretzler, M.6
  • 119
    • 84895069879 scopus 로고    scopus 로고
    • Polycystic kidney disease: Periostin is involved in cell proliferation and interstitial fibrosis in polycystic kidney disease
    • Bible E (2014) Polycystic kidney disease: Periostin is involved in cell proliferation and interstitial fibrosis in polycystic kidney disease. Nat Rev Nephrol 10:66
    • (2014) Nat Rev Nephrol , vol.10 , pp. 66
    • Bible, E.1
  • 120
    • 84930896120 scopus 로고    scopus 로고
    • Periostin: a novel tissue biomarker correlates with chronicity index and renal function in lupus nephritis patients.
    • pii:0961203314566634
    • Wantanasiri P, Satirapoj B, Charoenpitakchai M, Aramwit P (2015) Periostin: a novel tissue biomarker correlates with chronicity index and renal function in lupus nephritis patients. Lupus. pii:0961203314566634
    • (2015) Lupus
    • Wantanasiri, P.1    Satirapoj, B.2    Charoenpitakchai, M.3    Aramwit, P.4
  • 121
    • 84925070727 scopus 로고    scopus 로고
    • Matricellular protein periostin contributes to hepatic inflammation and fibrosis
    • Huang Y, Liu W, Xiao H, Maitikabili A, Lin Q, Wu T et al (2015) Matricellular protein periostin contributes to hepatic inflammation and fibrosis. Am J Pathol 185:786-797
    • (2015) Am J Pathol , vol.185 , pp. 786-797
    • Huang, Y.1    Liu, W.2    Xiao, H.3    Maitikabili, A.4    Lin, Q.5    Wu, T.6
  • 122
    • 84899910899 scopus 로고    scopus 로고
    • Periostin expression is upregulated and associated with myocardical fibrosis in human failing hearts
    • Zhao S, Wu H, Xia W, Chen X, Zhu S, Zhang S et al (2014) Periostin expression is upregulated and associated with myocardical fibrosis in human failing hearts. J Cardiol 63:373-378
    • (2014) J Cardiol , vol.63 , pp. 373-378
    • Zhao, S.1    Wu, H.2    Xia, W.3    Chen, X.4    Zhu, S.5    Zhang, S.6
  • 123
    • 84865682101 scopus 로고    scopus 로고
    • Serum periostin as a marker of Th2-dependent eosinophilic airway inflammation
    • Nair P, Kraft M (2012) Serum periostin as a marker of Th2-dependent eosinophilic airway inflammation. J Allergy Clin Immunol 130:655-656
    • (2012) J Allergy Clin Immunol , vol.130 , pp. 655-656
    • Nair, P.1    Kraft, M.2
  • 124
    • 67650451085 scopus 로고    scopus 로고
    • The multifaceted role of periostin in tumorigenesis
    • Ruan K, Bao S, Ouyang G (2009) The multifaceted role of periostin in tumorigenesis. Cell Mol Life Sci 66:2219-2230
    • (2009) Cell Mol Life Sci , vol.66 , pp. 2219-2230
    • Ruan, K.1    Bao, S.2    Ouyang, G.3
  • 126
    • 84901780251 scopus 로고    scopus 로고
    • Elevated plasma galectin-3 is associated with near-term rehospitalization in heart failure: a pooled analysis of 3 clinical trials
    • Meijers WC, Januzzi JL, DeFilippi C, Adourian AS, Shah SJ, van Veldhuisen DJ et al (2014) Elevated plasma galectin-3 is associated with near-term rehospitalization in heart failure: a pooled analysis of 3 clinical trials. Am Heart J 167:853-860
    • (2014) Am Heart J , vol.167 , pp. 853-860
    • Meijers, W.C.1    Januzzi, J.L.2    DeFilippi, C.3    Adourian, A.S.4    Shah, S.J.5    Veldhuisen, D.J.6
  • 127
    • 85015481593 scopus 로고    scopus 로고
    • Role of galectins in re-epithelialization of wounds
    • Panjwani N (2014) Role of galectins in re-epithelialization of wounds. Ann Transl Med 2:89
    • (2014) Ann Transl Med , vol.2 , pp. 89
    • Panjwani, N.1
  • 128
    • 85015477850 scopus 로고    scopus 로고
    • Platelets and galectins
    • Schattner M (2014) Platelets and galectins. Ann Transl Med 2:85
    • (2014) Ann Transl Med , vol.2 , pp. 85
    • Schattner, M.1
  • 130
    • 70450265476 scopus 로고    scopus 로고
    • Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation
    • Niki T, Tsutsui S, Hirose S, Aradono S, Sugimoto Y, Takeshita K et al (2009) Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation. J Biol Chem 284:32344-32352
    • (2009) J Biol Chem , vol.284 , pp. 32344-32352
    • Niki, T.1    Tsutsui, S.2    Hirose, S.3    Aradono, S.4    Sugimoto, Y.5    Takeshita, K.6
  • 131
    • 84889817722 scopus 로고    scopus 로고
    • Preventive effect of galectin-9 on double-stranded RNA-induced airway hyperresponsiveness in an exacerbation model of mite antigen-induced asthma in mice
    • Katoh S, Shimizu H, Obase Y, Oomizu S, Niki T, Ikeda M et al (2013) Preventive effect of galectin-9 on double-stranded RNA-induced airway hyperresponsiveness in an exacerbation model of mite antigen-induced asthma in mice. Exp Lung Res 39:453-462
    • (2013) Exp Lung Res , vol.39 , pp. 453-462
    • Katoh, S.1    Shimizu, H.2    Obase, Y.3    Oomizu, S.4    Niki, T.5    Ikeda, M.6
  • 133
    • 82655173829 scopus 로고    scopus 로고
    • Galectin-3 a jack-of-all-trades in cancer
    • Newlaczyl AU, Yu LG (2011) Galectin-3 a jack-of-all-trades in cancer. Cancer Lett 313:123-128
    • (2011) Cancer Lett , vol.313 , pp. 123-128
    • Newlaczyl, A.U.1    Yu, L.G.2
  • 134
    • 0026770786 scopus 로고
    • Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin
    • Hsu DK, Zuberi RI, Liu FT (1992) Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin. J Biol Chem 267:14167-14174
    • (1992) J Biol Chem , vol.267 , pp. 14167-14174
    • Hsu, D.K.1    Zuberi, R.I.2    Liu, F.T.3
  • 135
    • 9644275601 scopus 로고    scopus 로고
    • Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma
    • Zuberi RI, Hsu DK, Kalayci O, Chen HY, Sheldon HK, Yu L et al (2004) Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol 165:2045-2053
    • (2004) Am J Pathol , vol.165 , pp. 2045-2053
    • Zuberi, R.I.1    Hsu, D.K.2    Kalayci, O.3    Chen, H.Y.4    Sheldon, H.K.5    Yu, L.6
  • 136
    • 31144445789 scopus 로고    scopus 로고
    • Inhibition of chronic airway inflammation and remodeling by galectin-3 gene therapy in a murine model
    • López E, del Pozo V, Miguel T, Sastre B, Seoane C, Civantos E et al (2006) Inhibition of chronic airway inflammation and remodeling by galectin-3 gene therapy in a murine model. J Immunol 176:1943-1950
    • (2006) J Immunol , vol.176 , pp. 1943-1950
    • López, E.1    Pozo, V.2    Miguel, T.3    Sastre, B.4    Seoane, C.5    Civantos, E.6
  • 137
    • 34248231698 scopus 로고    scopus 로고
    • Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD
    • Pilette C, Colinet B, Kiss R, André S, Kaltner H, Gabius HJ (2007) Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD. Eur Respir J 29:914-922
    • (2007) Eur Respir J , vol.29 , pp. 914-922
    • Pilette, C.1    Colinet, B.2    Kiss, R.3    André, S.4    Kaltner, H.5    Gabius, H.J.6
  • 139
    • 84927711820 scopus 로고    scopus 로고
    • Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β
    • Gao P, Gibson PG, Baines KJ, Yang I, Upham JW, Reynolds PN et al (2015) Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β. Respir Res 16:5
    • (2015) Respir Res , vol.16 , pp. 5
    • Gao, P.1    Gibson, P.G.2    Baines, K.J.3    Yang, I.4    Upham, J.W.5    Reynolds, P.N.6
  • 142
    • 84926647762 scopus 로고    scopus 로고
    • Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease
    • Christenson SA, Steiling K, van den Berge M, Hijazi K, Hiemstra PS, Postma DS et al (2015) Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 191:758-766
    • (2015) Am J Respir Crit Care Med , vol.191 , pp. 758-766
    • Christenson, S.A.1    Steiling, K.2    Berge, M.3    Hijazi, K.4    Hiemstra, P.S.5    Postma, D.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.