메뉴 건너뛰기




Volumn 11, Issue 4, 2014, Pages 531-536

Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma

Author keywords

Anti IL 5; Eosinophils; Phenotype; Severe asthma

Indexed keywords

CORTICOSTEROID; MEPOLIZUMAB; PLACEBO; ANTIASTHMATIC AGENT; INTERLEUKIN 5; MONOCLONAL ANTIBODY;

EID: 84903608027     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201310-354OC     Document Type: Article
Times cited : (170)

References (22)
  • 2
    • 84875920801 scopus 로고    scopus 로고
    • Developmental current and future therapy for severe asthma
    • Nakamura Y. Developmental current and future therapy for severe asthma. Inflamm Allergy Drug Targets 2013;12:54-60.
    • (2013) Inflamm Allergy Drug Targets , vol.12 , pp. 54-60
    • Nakamura, Y.1
  • 3
    • 84865421859 scopus 로고    scopus 로고
    • Inhibition of interleukin-5 for the treatment of eosinophilic diseases
    • Corren J. Inhibition of interleukin-5 for the treatment of eosinophilic diseases. Discov Med 2012;13:305-312.
    • (2012) Discov Med , vol.13 , pp. 305-312
    • Corren, J.1
  • 5
    • 84865145614 scopus 로고    scopus 로고
    • Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
    • Pavord ID, Korn S, Howarth P, Bleecker ER, Buhl R, Keene ON, Ortega H, Chanez P. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet 2012;380:651-659.
    • (2012) Lancet , vol.380 , pp. 651-659
    • Pavord, I.D.1    Korn, S.2    Howarth, P.3    Bleecker, E.R.4    Buhl, R.5    Keene, O.N.6    Ortega, H.7    Chanez, P.8
  • 7
    • 84873408369 scopus 로고    scopus 로고
    • Targeting eosinophils in allergy, inflammation and beyond
    • Fulkerson PC, Rothenberg ME. Targeting eosinophils in allergy, inflammation and beyond. Nat Rev Drug Discov 2013;12:117-129.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 117-129
    • Fulkerson, P.C.1    Rothenberg, M.E.2
  • 10
    • 84858322573 scopus 로고    scopus 로고
    • Clinical update on the use of biomarkers of airway inflammation in the management of asthma
    • Wadsworth S, Sin D, Dorscheid D. Clinical update on the use of biomarkers of airway inflammation in the management of asthma. J Asthma Allergy 2011;4:77-86.
    • (2011) J Asthma Allergy , vol.4 , pp. 77-86
    • Wadsworth, S.1    Sin, D.2    Dorscheid, D.3
  • 12
    • 84873136114 scopus 로고    scopus 로고
    • Eosinophils as diagnostic tools in chronic lung disease
    • Eltboli O, Brightling CE. Eosinophils as diagnostic tools in chronic lung disease. Expert Rev Respir Med 2013;7:33-42.
    • (2013) Expert Rev Respir Med , vol.7 , pp. 33-42
    • Eltboli, O.1    Brightling, C.E.2
  • 13
    • 73449086493 scopus 로고    scopus 로고
    • Global Initiative for Asthma (GINA) [accessed 2013 Dec 15]. Available from
    • Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention [Internet]. [accessed 2013 Dec 15]. Available from: http://www.ginasthma.org/local/uploads/files/GINA-Report-March13.pdf
    • Global Strategy for Asthma Management and Prevention [Internet]
  • 14
    • 84866378527 scopus 로고    scopus 로고
    • Eosinophilic asthma?
    • Spector SL, Tan RA. Is a single blood eosinophil count a reliable marker for "eosinophilic asthma?". J Asthma 2012;49:807-810.
    • (2012) J Asthma , vol.49 , pp. 807-810
    • Spector, S.L.1    Tan, R.A.2
  • 15
    • 0022755658 scopus 로고
    • Human eosinophil heterogeneity
    • Sorice F, De Simone C. Human eosinophil heterogeneity. Ric Clin Lab 1986;16:429-434.
    • (1986) Ric Clin Lab , vol.16 , pp. 429-434
    • Sorice, F.1    De Simone, C.2
  • 18
    • 34447111954 scopus 로고
    • Normal variation in the count of circulating eosinophils in man
    • Acland JD, Gould AH. Normal variation in the count of circulating eosinophils in man. J Physiol 1956;133:456-466.
    • (1956) J Physiol , vol.133 , pp. 456-466
    • Acland, J.D.1    Gould, A.H.2
  • 20
    • 84873736081 scopus 로고    scopus 로고
    • Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma
    • Ullmann N, Bossley CJ, Fleming L, Silvestri M, Bush A, Saglani S. Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma. Allergy 2013;68:402-406.
    • (2013) Allergy , vol.68 , pp. 402-406
    • Ullmann, N.1    Bossley, C.J.2    Fleming, L.3    Silvestri, M.4    Bush, A.5    Saglani, S.6
  • 22
    • 84884905728 scopus 로고    scopus 로고
    • Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects
    • e1-e5
    • Malinovschi A, Fonseca JA, Jacinto T, Alving K, Janson C. Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey subjects. J Allergy Clin Immunol 2013; 132:821-827, e1-e5.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 821-827
    • Malinovschi, A.1    Fonseca, J.A.2    Jacinto, T.3    Alving, K.4    Janson, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.