Mitochondrial impairment and oxidative stress compromise autophagosomal degradation of α-synuclein in oligodendroglial cells

Journal of Neurochemistry

Volumn 135, Issue 1, 2015, Pages 194-205

  Pukaß, Katharina ^a   Goldbaum, Olaf ^a   Richter Landsberg, Christiane ^a  

^a UNIVERSITY OF OLDENBURG   (Germany)

Author keywords

3 NP; CCCP; glial cytoplasmic inclusions; multiple system atrophy; oligodendrocytes; ubiquitin proteasome system

Indexed keywords

ALPHA SYNUCLEIN; AUTOPHAGY PROTEIN 5; CELL PROTEIN; GREEN FLUORESCENT PROTEIN; LC3 PROTEIN; PROTEIN P62; UNCLASSIFIED DRUG; 3-NITROPROPIONIC ACID; NERVE PROTEIN; NITRO DERIVATIVE; PROPIONIC ACID DERIVATIVE; SNCA PROTEIN, RAT;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INTERNALIZATION; NONHUMAN; OLIGODENDROGLIA; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; SYNUCLEINOPATHY; ANIMAL; CELL CULTURE; CYTOPLASM; METABOLISM; MITOCHONDRION; MULTIPLE SYSTEM ATROPHY; PHYSIOLOGY;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CELLS, CULTURED; CYTOPLASM; MITOCHONDRIA; MULTIPLE SYSTEM ATROPHY; NERVE TISSUE PROTEINS; NITRO COMPOUNDS; OLIGODENDROGLIA; OXIDATIVE STRESS; PROPIONATES; RATS;

EID: 84942504910     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13256     Document Type: Article

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