Antidiabetic drugs restore abnormal transport of amyloid-β across the blood-brain barrier and memory impairment in db/db mice

Neuropharmacology

Volumn 101, Issue , 2016, Pages 123-136

  Chen, Fang ^a   Dong, Rong Rong ^a   Zhong, Kai Long ^a   Ghosh, Arijit ^a   Tang, Su Su ^a   Long, Yan ^a   Hu, Mei ^a   Miao, Ming Xing ^a   Liao, Jian Min ^a   Sun, Hong Bing ^a   Kong, Ling Yi ^a   Hong, Hao ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Advanced glycation end products; Amyloid ; Antidiabetic drugs; Blood brain barrier; Hippocampal synaptic plasticity; Low density lipoprotein receptor related protein 1

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; ANTIDIABETIC AGENT; CASPASE 3; GLIBENCLAMIDE; GLUCOSE; INSULIN; INSULIN GLARGINE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR RELA; IODINE; LEPTIN RECEPTOR; LEPTIN RECEPTOR, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; CONTROLLED STUDY; DB/DB MOUSE; GLUCOSE BLOOD LEVEL; HIPPOCAMPUS; HYPERINSULINEMIA; LONG TERM POTENTIATION; MALE; MEMBRANE TRANSPORT; MEMORY DISORDER; MORRIS WATER MAZE TEST; MOUSE; NERVE CELL PLASTICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; Y-MAZE TEST; ANIMAL; APOPTOSIS; BLOOD; COMPLICATION; DIET RESTRICTION; DISEASE MODEL; DRUG EFFECTS; EXPLORATORY BEHAVIOR; GENETICS; MAZE TEST; MEMORY DISORDERS; METABOLISM; MUTANT MOUSE STRAIN; PHYSIOLOGY;

ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR; AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FASTING; HIPPOCAMPUS; HYPOGLYCEMIC AGENTS; INSULIN; IODINE ISOTOPES; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, MUTANT STRAINS; RECEPTORS, LEPTIN;

EID: 84942287910     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.07.023     Document Type: Article

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