Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NFκB signaling cascades

Toxicology Letters

Volumn 239, Issue 2, 2015, Pages 97-107

  Liu, Jin Tao ^a   Chen, Bei Yu ^b   Zhang, Jie Qiong ^a   Kuang, Fang ^a   Chen, Liang Wei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Astrogliosis; Hippocampus; Lead toxicity; Microgliosis; Neurogenesis

Indexed keywords

BROXURIDINE; CD28 ANTIGEN; DOUBLECORTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LEAD; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; MYD88 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN LEVEL; CELL ACTIVATION; CONTROLLED STUDY; DENTATE GYRUS; GLIOSIS; HIPPOCAMPAL TISSUE; HIPPOCAMPUS; INFLAMMATION; LEAD BLOOD LEVEL; LEAD POISONING; MICROGLIA; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; AGING; ANIMAL; ASTROCYTE; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY;

AGING; ANIMALS; ASTROCYTES; BROMODEOXYURIDINE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LEAD; MICE; MICE, INBRED C57BL; MICROGLIA; MYELOID DIFFERENTIATION FACTOR 88; NEURONS; NF-KAPPA B; TOLL-LIKE RECEPTOR 4;

EID: 84942103742     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.09.015     Document Type: Article

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