Toll-like receptor 4 signaling contributes to paclitaxel-induced peripheral neuropathy

Journal of Pain

Volumn 15, Issue 7, 2014, Pages 712-725

  Li, Yan ^a   Zhang, Haijun ^a   Zhang, Hongmei ^a   Kosturakis, Alyssa K ^a   Jawad, Abdul Basit ^b   Dougherty, Patrick M ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

DRG; LPS RS; MyD88; Neuropathy; spinal cord; TLR4; TRIF

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CALCITONIN GENE RELATED PEPTIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOLECTIN B4; MYELOID DIFFERENTIATION FACTOR 88; PACLITAXEL; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; ANTINEOPLASTIC AGENT; MYD88 PROTEIN, RAT; NERVE PROTEIN; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL SIZE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIMERIZATION; DRUG INDUCED DISEASE; IMMUNOHISTOCHEMISTRY; INDUCTION CHEMOTHERAPY; MAINTENANCE CHEMOTHERAPY; MALE; MICROGLIA; MOTOR PERFORMANCE; NERVOUS TISSUE; NONHUMAN; PERIPHERAL NEUROPATHY; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RHODOBACTER SPHAEROIDES; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; SPINAL GANGLION; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NERVE CELL; PAIN THRESHOLD; PATHOLOGY; PERIPHERAL NERVOUS SYSTEM DISEASES; SPRAGUE DAWLEY RAT; STIMULATION; TIME; TOXICITY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASTROCYTES; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; MALE; MYELOID DIFFERENTIATION FACTOR 88; NERVE TISSUE PROTEINS; NEURONS; PACLITAXEL; PAIN THRESHOLD; PERIPHERAL NERVOUS SYSTEM DISEASES; PHYSICAL STIMULATION; POLYSACCHARIDES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 4;

EID: 84903552041     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2014.04.001     Document Type: Article

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