Correlation of antioxidant activities with theoretical studies for new hydrazone compounds bearing a 3,4,5-trimethoxy benzyl moiety

European Journal of Medicinal Chemistry

Volumn 103, Issue , 2015, Pages 497-505

  Kareem, Huda S ^a,b   Ariffin, Azhar ^a   Nordin, Nurdiana ^a   Heidelberg, Thorsten ^a   Abdul Aziz, Azlina ^a   Kong, Kin Weng ^a   Yehye, Wageeh A ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b MINISTRY OF EDUCATION   (Iraq)

Author keywords

Antioxidant; Bond dissociation energy (BDE); Hydrazone; Hydrogen atom transfer; Single electron transfer; Spin density (SD)

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 3,4,5 TRIMETHOXY BENZYL DERIVATIVE; 4 (3,4,5 TRIMETHOXY BENZYLOXY)BENZOHYDRAZIDE DERIVATIVE; 4 (3,4,5 TRIMETHOXYBENZYLOXY)BENZOHYDRAZIDE; ALDEHYDE; ANTIOXIDANT; ASCORBIC ACID; BUTYLCRESOL; ETHYL 4 [(3,4,5 TRIMETHOXYBENZYL)OXY]BENZOATE; HYDRAZONE DERIVATIVE; HYDROXYL GROUP; IMINE; N (5 BROMO 3 CHLORO 2 HYDROXYBENZYLIDENE) 4 (3,4,5 TRIMETHOXYBENZYLOXY)BENZO HYDRAZIDE; PHENOL; SCAVENGER; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DENSITY FUNCTIONAL THEORY; DPPH RADICAL SCAVENGING ASSAY; DRUG DESIGN; DRUG SYNTHESIS; EXPERIMENTAL STUDY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; IC50; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; THEORETICAL STUDY; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; OXIDATIVE STRESS; QUANTUM THEORY; SYNTHESIS;

ANTIOXIDANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDRAZONES; MOLECULAR STRUCTURE; OXIDATIVE STRESS; QUANTUM THEORY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84942085314     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.09.016     Document Type: Article

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