Naphthalene combretastatin analogues: Synthesis, cytotoxicity and antitubulin activity

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 19, Issue 6, 2004, Pages 521-540

  Medarde, Manuel ^a   Maya, Ana B S ^a   Pérez Melero, Concepción ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Combretastatin analogues; Cytotoxicity; Naphthalene derivatives; Quinoline derivatives; S.A.R.; Tubulin polymerization inhibition

Indexed keywords

AMPHETINILE; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; COLCHICINE; COLCHICINE DERIVATIVE; COMBRESTATIN; COMBRESTATIN A1; COMBRESTATIN A4; COMBRESTATIN B1; COMBRESTATIN C1; COMBRESTATIN D1; COMBRESTATIN DERIVATIVE; CORNIGERINE; CYTOTOXIC AGENT; FLAVONOID; MAYTANSINE; NAPHTHALENE DERIVATIVE; NOCODAZOLE; PACLITAXEL; PODOPHYLLOTOXIN; QUINOLONE DERIVATIVE; RHIZOXIN; ROTENONE; SANGUINARINE; SULFONAMIDE; THIOCOLCHICINE; TUBULIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINBLASTINE; VINCA ALKALOID;

ANIMAL CELL; ARTICLE; CANCER CHEMOTHERAPY; CHEMICAL MODIFICATION; COMBRETUM; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIBENZYLS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; NAPHTHALENES; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; TUBULIN MODULATORS;

EID: 11244320417     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360412331280473     Document Type: Article

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