-
1
-
-
84858225391
-
2012 Alzheimer's Disease Facts and Figures
-
Alzheimer's Association. 2012 Alzheimer's Disease Facts and Figures. Alzheimers Dement 8(2): 131-68 (2012).
-
(2012)
Alzheimers Dement
, vol.8
, Issue.2
, pp. 131-168
-
-
-
2
-
-
77957951112
-
Revising the definition of Alzheimer's disease: A new lexicon
-
Dubois B, Feldman HH, Jacova C, Cummings JL, Dekosky ST, Barberger-Gateau P, et al. Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol 9(11): 1118-1127 (2010).
-
(2010)
Lancet Neurol
, vol.9
, Issue.11
, pp. 1118-1127
-
-
Dubois, B.1
Feldman, H.H.2
Jacova, C.3
Cummings, J.L.4
Dekosky, S.T.5
Barberger-Gateau, P.6
-
3
-
-
84872379077
-
Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers
-
Jack CR, Knopman DS, Jagust WJ, Petersen RC, Weiner MW, Aisen PS, et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol 12(2): 207-216 (2013).
-
(2013)
Lancet Neurol
, vol.12
, Issue.2
, pp. 207-216
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Petersen, R.C.4
Weiner, M.W.5
Aisen, P.S.6
-
4
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, Bennett DA, Craft S, Fagan AM, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7(3): 280-292 (2011).
-
(2011)
Alzheimers Dement
, vol.7
, Issue.3
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
Bennett, D.A.4
Craft, S.5
Fagan, A.M.6
-
5
-
-
70450219539
-
Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease
-
Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, Martins RN. Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease. J Neurochem 111(6): 1275-1308 (2009).
-
(2009)
J Neurochem
, vol.111
, Issue.6
, pp. 1275-1308
-
-
Martins, I.J.1
Berger, T.2
Sharman, M.J.3
Verdile, G.4
Fuller, S.J.5
Martins, R.N.6
-
6
-
-
74649084820
-
Midlife predictors of Alzheimer's disease
-
Bendlin BB, Carlsson CM, Gleason CE, Johnson SC, Sodhi A, Gallagher CL, et al. Midlife predictors of Alzheimer's disease. Maturitas 65(2): 131-137 (2010).
-
(2010)
Maturitas
, vol.65
, Issue.2
, pp. 131-137
-
-
Bendlin, B.B.1
Carlsson, C.M.2
Gleason, C.E.3
Johnson, S.C.4
Sodhi, A.5
Gallagher, C.L.6
-
7
-
-
79955484414
-
Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33, and CD2AP are associated with Alzheimer's disease
-
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, et al. Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33, and CD2AP are associated with Alzheimer's disease. Nat Genet 43(5): 429-435 (2011).
-
(2011)
Nat Genet
, vol.43
, Issue.5
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
Gerrish, A.4
Lambert, J.C.5
Carrasquillo, M.M.6
-
8
-
-
84920703987
-
Alzheimer's disease risk genes and mechanisms of disease pathogenesis
-
Karch CM, Goate AM. Alzheimer's disease risk genes and mechanisms of disease pathogenesis. Biol Psychiatry 77(1): 43-51 (2015).
-
(2015)
Biol Psychiatry
, vol.77
, Issue.1
, pp. 43-51
-
-
Karch, C.M.1
Goate, A.M.2
-
9
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes
-
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes. Nat Genet 41(10): 1088-1093 (2009).
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
-
10
-
-
84876813113
-
TREM2: A new risk factor for Alzheimer's disease
-
Singaraja RR. TREM2: a new risk factor for Alzheimer's disease. Clin Genet 83(6): 525-526 (2013).
-
(2013)
Clin Genet
, vol.83
, Issue.6
, pp. 525-526
-
-
Singaraja, R.R.1
-
11
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
Guerreiro R, Wojtas A, Bras J, Gibbs JR, Rohrer JD, Gurunlian N, et al. TREM2 variants in Alzheimer's disease. New Engl J Med 368(2): 117-127 (2013).
-
(2013)
New Engl J Med
, vol.368
, Issue.2
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Gibbs, J.R.4
Rohrer, J.D.5
Gurunlian, N.6
-
12
-
-
84904542042
-
Deficits in the miRNA-34aregulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update
-
Bhattacharjee S, Zhao Y, Lukiw WJ. Deficits in the miRNA-34aregulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update. Front Aging Neurosci 6: 116 (2014).
-
(2014)
Front Aging Neurosci
, vol.6
, pp. 116
-
-
Bhattacharjee, S.1
Zhao, Y.2
Lukiw, W.J.3
-
13
-
-
84919329825
-
Polymorphism of the OLR1 3'UTR potential microRNA binding site and risk of Alzheimer's disease: A meta-analysis
-
Kong Y, Wu JB, Wang X, Zhao JF, Song H, Yuan LD. Polymorphism of the OLR1 3'UTR potential microRNA binding site and risk of Alzheimer's disease: a meta-analysis. Genet Mol Res 13(4): 10162-72 (2014).
-
(2014)
Genet Mol Res
, vol.13
, Issue.4
, pp. 10162-10172
-
-
Kong, Y.1
Wu, J.B.2
Wang, X.3
Zhao, J.F.4
Song, H.5
Yuan, L.D.6
-
14
-
-
84866134171
-
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients
-
Long JM, Ray B, Lahiri DK. MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. J Biol Chem 287(37): 31298-310 (2012).
-
(2012)
J Biol Chem
, vol.287
, Issue.37
, pp. 31298-31310
-
-
Long, J.M.1
Ray, B.2
Lahiri, D.K.3
-
15
-
-
84894450407
-
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects
-
Long JM, Ray B, Lahiri DK. MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. J Biol Chem 289(8): 5184-98 (2014).
-
(2014)
J Biol Chem
, vol.289
, Issue.8
, pp. 5184-5198
-
-
Long, J.M.1
Ray, B.2
Lahiri, D.K.3
-
16
-
-
84907979350
-
Circulating miRNAs as potential biomarkers in Alzheimer's disease
-
Galimberti D, Villa C, Fenoglio C, Serpente M, Ghezzi L, Cioffi SM, et al. Circulating miRNAs as potential biomarkers in Alzheimer's disease. J Alzheimers Dis 42(4): 1261-7 (2014).
-
(2014)
J Alzheimers Dis
, vol.42
, Issue.4
, pp. 1261-1267
-
-
Galimberti, D.1
Villa, C.2
Fenoglio, C.3
Serpente, M.4
Ghezzi, L.5
Cioffi, S.M.6
-
17
-
-
84859309442
-
Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation
-
Barbash S, Soreq H.Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation. Curr Alzheimer Res 9(4): 425-35 (2012).
-
(2012)
Curr Alzheimer Res
, vol.9
, Issue.4
, pp. 425-435
-
-
Barbash, S.1
Soreq, H.2
-
19
-
-
79952747862
-
Alzheimer's disease
-
Ballard C, Gauthier S, Corbett A, Brayne C, Aarsland D, Jones E. Alzheimer's disease. Lancet 377(9770): 1019-1031 (2011).
-
(2011)
Lancet
, vol.377
, Issue.9770
, pp. 1019-1031
-
-
Ballard, C.1
Gauthier, S.2
Corbett, A.3
Brayne, C.4
Aarsland, D.5
Jones, E.6
-
20
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
Tanzi RE, Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120(4): 545-555 (2005).
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
21
-
-
27144515872
-
Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI
-
Jack CR, Jr., Shiung MM, Weigand SD, O'Brien PC, Gunter JL, Boeve BF, et al. Brain atrophy rates predict subsequent clinical conversion in normal elderly and amnestic MCI. Neurology 65(8): 1227-1231 (2005).
-
(2005)
Neurology
, vol.65
, Issue.8
, pp. 1227-1231
-
-
Jack, C.R.1
Shiung, M.M.2
Weigand, S.D.3
O'Brien, P.C.4
Gunter, J.L.5
Boeve, B.F.6
-
22
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack CR, Jr., Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 9(1): 119-128 (2010).
-
(2010)
Lancet Neurol
, vol.9
, Issue.1
, pp. 119-128
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Shaw, L.M.4
Aisen, P.S.5
Weiner, M.W.6
-
23
-
-
84856002055
-
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
-
Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement 8(1): 1-13 (2012).
-
(2012)
Alzheimers Dement
, vol.8
, Issue.1
, pp. 1-13
-
-
Hyman, B.T.1
Phelps, C.H.2
Beach, T.G.3
Bigio, E.H.4
Cairns, N.J.5
Carrillo, M.C.6
-
24
-
-
0021207461
-
Alzheimer's disease and Down syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner GG, Wong CW. Alzheimer's disease and Down syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun 122(3): 1131-1135 (1984).
-
(1984)
Biochem Biophys Res Commun
, vol.122
, Issue.3
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
25
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297(5580): 353-356 (2002).
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
26
-
-
79959886270
-
Amyloid precursor protein processing and Alzheimer's disease
-
O'Brien RJ, Wong PC. Amyloid precursor protein processing and Alzheimer's disease. Annu Rev Neurosci 34: 185-204 (2011).
-
(2011)
Annu Rev Neurosci
, vol.34
, pp. 185-204
-
-
O'Brien, R.J.1
Wong, P.C.2
-
27
-
-
57649221135
-
Amyloid precursor protein trafficking, processing, and function
-
Thinakaran G, Koo EH. Amyloid precursor protein trafficking, processing, and function. J Biol Chem 283(44): 29615-29619 (2008).
-
(2008)
J Biol Chem
, vol.283
, Issue.44
, pp. 29615-29619
-
-
Thinakaran, G.1
Koo, E.H.2
-
28
-
-
67349142021
-
Neurovascular mechanisms and bloodbrain barrier disorder in Alzheimer's disease
-
Bell RD, Zlokovic BV. Neurovascular mechanisms and bloodbrain barrier disorder in Alzheimer's disease. Acta Neuropathol 118(1): 103-113 (2009).
-
(2009)
Acta Neuropathol
, vol.118
, Issue.1
, pp. 103-113
-
-
Bell, R.D.1
Zlokovic, B.V.2
-
29
-
-
41149157623
-
Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease
-
Weller RO, Subash M, Preston SD, Mazanti I, Carare RO. Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer's disease. Brain Pathol 18(2): 253-266 (2008).
-
(2008)
Brain Pathol
, vol.18
, Issue.2
, pp. 253-266
-
-
Weller, R.O.1
Subash, M.2
Preston, S.D.3
Mazanti, I.4
Carare, R.O.5
-
30
-
-
40149099870
-
Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: Significance for cerebral amyloid angiopathy and neuroimmunology
-
Carare RO, Bernardes-Silva, M, Newman, TA, Page, AM, Nicoll, JAR, Perry VH, et al. Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology. Neuropathol App Neurobiol 34: 131-144 (2008).
-
(2008)
Neuropathol App Neurobiol
, vol.34
, pp. 131-144
-
-
Carare, R.O.1
Bernardes-Silva, M.2
Newman, T.A.3
Page, A.M.4
Nicoll, J.A.R.5
Perry, V.H.6
-
31
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8(2): 101-112 (2007).
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.2
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
33
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimer's disease
-
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, et al. Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science 330(6012): 1774 (2010).
-
(2010)
Science
, vol.330
, Issue.6012
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
Morris, J.C.6
-
34
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer's β-amyloid precursor protein depends on lipid rafts
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K. Amyloidogenic processing of the Alzheimer's β-amyloid precursor protein depends on lipid rafts. J Cell Biol 160(1): 113-123 (2003).
-
(2003)
J Cell Biol
, vol.160
, Issue.1
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
35
-
-
84880712325
-
A phase 3 trial of semagacestat for treatment of Alzheimer's disease
-
Doody RS, Raman R, Farlow M, Iwatsubo T, Vellas B, Joffe S, et al. A phase 3 trial of semagacestat for treatment of Alzheimer's disease.N Engl J Med 369(4): 341-50 (2013).
-
(2013)
N Engl J Med
, vol.369
, Issue.4
, pp. 341-350
-
-
Doody, R.S.1
Raman, R.2
Farlow, M.3
Iwatsubo, T.4
Vellas, B.5
Joffe, S.6
-
36
-
-
84909971843
-
Lessons from a failed γ -secretase Alzheimer trial
-
De Strooper B. Lessons from a failed γ -secretase Alzheimer trial. Cell 159(4): 721-6 (2014).
-
(2014)
Cell
, vol.159
, Issue.4
, pp. 721-726
-
-
De Strooper, B.1
-
37
-
-
84864471159
-
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
-
Jonsson T, Atwal JK, Steinberg S, Snaedal J, Jonsson PV, Bjornsson S, et al. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 488: 96-99 (2012).
-
(2012)
Nature
, vol.488
, pp. 96-99
-
-
Jonsson, T.1
Atwal, J.K.2
Steinberg, S.3
Snaedal, J.4
Jonsson, P.V.5
Bjornsson, S.6
-
39
-
-
84892748542
-
Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease
-
Doody RS, Thomas RG, Farlow M, Iwatsubo T, Vellas B, Joffe S, et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med 370(4): 311-21 (2014).
-
(2014)
N Engl J Med
, vol.370
, Issue.4
, pp. 311-321
-
-
Doody, R.S.1
Thomas, R.G.2
Farlow, M.3
Iwatsubo, T.4
Vellas, B.5
Joffe, S.6
-
40
-
-
0030805991
-
Frequency of stages of Alzheimer-related lesions in different age categories
-
Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging 18(4): 351-357 (1997).
-
(1997)
Neurobiol Aging
, vol.18
, Issue.4
, pp. 351-357
-
-
Braak, H.1
Braak, E.2
-
41
-
-
76649116890
-
Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity
-
Friedrich RP, Tepper K, Ronicke R, Soom M, Westermann M, Reymann K, et al. Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity. Proc Natl Acad Sci USA 107(5): 1942-1947 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.5
, pp. 1942-1947
-
-
Friedrich, R.P.1
Tepper, K.2
Ronicke, R.3
Soom, M.4
Westermann, M.5
Reymann, K.6
-
42
-
-
0037422540
-
Amyloid beta-protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways
-
Bitan G, Kirkitadze MD, Lomakin A, Vollers SS, Benedek GB, Teplow D. Amyloid beta-protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways. Proc Natl Acad Sci USA 100(1): 330-335 (2003).
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.1
, pp. 330-335
-
-
Bitan, G.1
Kirkitadze, M.D.2
Lomakin, A.3
Vollers, S.S.4
Benedek, G.B.5
Teplow, D.6
-
43
-
-
70349295278
-
Structure-neurotoxicity relationships of amyloid β -protein oligomers
-
Ono K, Condron MM, Teplow DB. Structure-neurotoxicity relationships of amyloid β -protein oligomers. Proc Natl Acad Sci 106(35): 14745-14750 (2009).
-
(2009)
Proc Natl Acad Sci
, vol.106
, Issue.35
, pp. 14745-14750
-
-
Ono, K.1
Condron, M.M.2
Teplow, D.B.3
-
44
-
-
64549140676
-
Structural characterization of a soluble amyloid beta-peptide oligomer
-
Yu L, Edalji R, Harlan JE, Holzman TF, Lopez AP, Labkovsky B, et al. Structural characterization of a soluble amyloid beta-peptide oligomer. Biochemistry 48(9): 1870-1877 (2009).
-
(2009)
Biochemistry
, vol.48
, Issue.9
, pp. 1870-1877
-
-
Yu, L.1
Edalji, R.2
Harlan, J.E.3
Holzman, T.F.4
Lopez, A.P.5
Labkovsky, B.6
-
45
-
-
77952542382
-
Biological markers of amyloid β-related mechanisms in Alzheimer's disease
-
Hampel H, Shen Y, Walsh DM, Aisen P, Shaw LM, Zetterberg H, et al. Biological markers of amyloid β-related mechanisms in Alzheimer's disease. Exp Neurol 223(2): 334-346 (2010).
-
(2010)
Exp Neurol
, vol.223
, Issue.2
, pp. 334-346
-
-
Hampel, H.1
Shen, Y.2
Walsh, D.M.3
Aisen, P.4
Shaw, L.M.5
Zetterberg, H.6
-
46
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, et al. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14(8): 837-842 (2008).
-
(2008)
Nat Med
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
-
47
-
-
84880759156
-
Neurotoxicity of amyloid b-protein: Synaptic and network dysfunction
-
Mucke L, Selkoe D. Neurotoxicity of amyloid b-protein: synaptic and network dysfunction. Cold Spring Harb Perspect Med 2(7): a006338 (2012).
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, Issue.7
-
-
Mucke, L.1
Selkoe, D.2
-
48
-
-
84875655895
-
Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature
-
Wyss-Coray T, Rogers J. Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med 2(1): a006346 (2012).
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, Issue.1
-
-
Wyss-Coray, T.1
Rogers, J.2
-
49
-
-
84872069366
-
Variant TREM2 as risk factor for Alzheimer's disease
-
Neumann H, Daly MJ. Variant TREM2 as risk factor for Alzheimer's disease. N Engl J Med 368(2): 182-184 (2013).
-
(2013)
N Engl J Med
, vol.368
, Issue.2
, pp. 182-184
-
-
Neumann, H.1
Daly, M.J.2
-
50
-
-
84936161018
-
Polygenic overlap between C-reactive protein, plasma lipids and Alzheimer's disease
-
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, et al. Polygenic overlap between C-reactive protein, plasma lipids and Alzheimer's disease. Circulation 131(23): 2061-9 (2015).
-
(2015)
Circulation
, vol.131
, Issue.23
, pp. 2061-2069
-
-
Desikan, R.S.1
Schork, A.J.2
Wang, Y.3
Thompson, W.K.4
Dehghan, A.5
Ridker, P.M.6
-
51
-
-
82755161978
-
Reactive astrocytes give neurons less support: Implications for Alzheimer's disease
-
Steele ML, Robinson SR. Reactive astrocytes give neurons less support: implications for Alzheimer's disease. Neurobiol Aging 33(2): 423.e1-423.e13 (2012).
-
(2012)
Neurobiol Aging
, vol.33
, Issue.2
, pp. 423.e1-423.e13
-
-
Steele, M.L.1
Robinson, S.R.2
-
52
-
-
80052846665
-
Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
-
Reddy PH. Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease. Brain Res 1415: 136-148 (2011).
-
(2011)
Brain Res
, vol.1415
, pp. 136-148
-
-
Reddy, P.H.1
-
53
-
-
39149122810
-
Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
-
Reddy PH, Beal MF. Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol Med 14(2): 45-53 (2008).
-
(2008)
Trends Mol Med
, vol.14
, Issue.2
, pp. 45-53
-
-
Reddy, P.H.1
Beal, M.F.2
-
54
-
-
79751537405
-
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
-
Calkins MJ, Reddy PH. Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons. Biochim Biophys Acta 1812(4): 507-513 (2011).
-
(2011)
Biochim Biophys Acta
, vol.1812
, Issue.4
, pp. 507-513
-
-
Calkins, M.J.1
Reddy, P.H.2
-
55
-
-
84863595757
-
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions
-
Stohr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, et al. Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci 109(27): 11025-11030 (2012).
-
(2012)
Proc Natl Acad Sci
, vol.109
, Issue.27
, pp. 11025-11030
-
-
Stohr, J.1
Watts, J.C.2
Mensinger, Z.L.3
Oehler, A.4
Grillo, S.K.5
DeArmond, S.J.6
-
56
-
-
84874853965
-
Mechanisms of protein seeding in neurodegenerative diseases
-
Walker L, Diamond MI, Duff KE, Hyman BT. Mechanisms of protein seeding in neurodegenerative diseases. JAMA Neurol 70(3): 304-310 (2013).
-
(2013)
JAMA Neurol
, vol.70
, Issue.3
, pp. 304-310
-
-
Walker, L.1
Diamond, M.I.2
Duff, K.E.3
Hyman, B.T.4
-
57
-
-
19944375450
-
Tau pathology in Alzheimer disease and other tauopathies
-
Iqbal K, Alonso Adel C, Chen S, Chohan MO, El-Akkad E, Gong CX, et al. Tau pathology in Alzheimer disease and other tauopathies. Biochim Biophys Acta 1739(2-3): 198-210 (2005).
-
(2005)
Biochim Biophys Acta
, vol.1739
, Issue.2-3
, pp. 198-210
-
-
Iqbal, K.1
Alonso Adel, C.2
Chen, S.3
Chohan, M.O.4
El-Akkad, E.5
Gong, C.X.6
-
58
-
-
0042307302
-
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure
-
Berriman J, Serpell LC, Oberg KA, Fink AL, Goedert M, Crowther RA. Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure. Proc Natl Acad Sci USA 100(15): 9034-9038 (2003).
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.15
, pp. 9034-9038
-
-
Berriman, J.1
Serpell, L.C.2
Oberg, K.A.3
Fink, A.L.4
Goedert, M.5
Crowther, R.A.6
-
59
-
-
0031583947
-
The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimer's disease
-
Tapiola T, Overmyer M, Lehtovirta M, Helisalmi S, Ramberg J, Alafuzoff I, et al. The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimer's disease. Neuroreport 8(18): 3961-3963 (1997).
-
(1997)
Neuroreport
, vol.8
, Issue.18
, pp. 3961-3963
-
-
Tapiola, T.1
Overmyer, M.2
Lehtovirta, M.3
Helisalmi, S.4
Ramberg, J.5
Alafuzoff, I.6
-
60
-
-
62449262536
-
Cerebrospinal fluid β-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain
-
Tapiola T, Alafuzoff I, Herukka SK, Parkkinen L, Hartikainene P, Soininen H, et al. Cerebrospinal fluid β-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. Arch Neurol 66(3): 382-389 (2009).
-
(2009)
Arch Neurol
, vol.66
, Issue.3
, pp. 382-389
-
-
Tapiola, T.1
Alafuzoff, I.2
Herukka, S.K.3
Parkkinen, L.4
Hartikainene, P.5
Soininen, H.6
-
61
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, et al. Trans-synaptic spread of tau pathology in vivo. PLoS One 7(2): e31302 (2012).
-
(2012)
PLoS One
, vol.7
, Issue.2
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
-
62
-
-
84902518916
-
Exploratory analyses of regional human brain distribution of the PET tau tracer F18-labeled T807 (AV-1541) in subjects with normal cognitive function or cognitive impairment thought to be due to Alzheimer's disease
-
Mintun M, Schwarz A, Joshi A, Shcherbinin S, Chien D, Elizarov A, et al. Exploratory analyses of regional human brain distribution of the PET tau tracer F18-labeled T807 (AV-1541) in subjects with normal cognitive function or cognitive impairment thought to be due to Alzheimer's disease. Alzheimers Dement 9(4): P842 (2013).
-
(2013)
Alzheimers Dement
, vol.9
, Issue.4
-
-
Mintun, M.1
Schwarz, A.2
Joshi, A.3
Shcherbinin, S.4
Chien, D.5
Elizarov, A.6
-
63
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow EM, Stamer K, Vogel R, Thies E, Mandelkow E. Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 24(8): 1079-1085 (2003).
-
(2003)
Neurobiol Aging
, vol.24
, Issue.8
, pp. 1079-1085
-
-
Mandelkow, E.M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
64
-
-
33746411112
-
Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?
-
Gotz J, Ittner LM, Kins S. Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease? J Neurochem 98(4): 993-1006 (2006).
-
(2006)
J Neurochem
, vol.98
, Issue.4
, pp. 993-1006
-
-
Gotz, J.1
Ittner, L.M.2
Kins, S.3
-
65
-
-
78751644048
-
Amyloid-beta and tau--a toxic pas de deux in Alzheimer's disease
-
Ittner LM, Gotz J. Amyloid-beta and tau--a toxic pas de deux in Alzheimer's disease. Nat Rev Neurosci 12(2): 65-72 (2011).
-
(2011)
Nat Rev Neurosci
, vol.12
, Issue.2
, pp. 65-72
-
-
Ittner, L.M.1
Gotz, J.2
-
66
-
-
44849122277
-
Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes
-
Fein JA, Sokolow S, Miller CA, Vinters HV, Yang F, Cole GM, et al. Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes. Am J Pathol 172(6): 1683-1692 (2008).
-
(2008)
Am J Pathol
, vol.172
, Issue.6
, pp. 1683-1692
-
-
Fein, J.A.1
Sokolow, S.2
Miller, C.A.3
Vinters, H.V.4
Yang, F.5
Cole, G.M.6
-
67
-
-
64649097658
-
FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease
-
Mosconi L, Mistur R, Switalski R, Tsui WH, Glodzik L, Li Y, et al. FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease. Eur J Nucl Med Mol Imaging 36(5): 811-822 (2009).
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, Issue.5
, pp. 811-822
-
-
Mosconi, L.1
Mistur, R.2
Switalski, R.3
Tsui, W.H.4
Glodzik, L.5
Li, Y.6
-
68
-
-
0036235195
-
Longitudinal PET evaluation of cerebral metabolic decline in dementia: A potential outcome measure in Alzheimer's disease treatment studies
-
Alexander GE, Chen K, Pietrini P, Rapoport SI, Reiman EM. Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies. Am J Psychiatry 159(5): 738-745 (2002).
-
(2002)
Am J Psychiatry
, vol.159
, Issue.5
, pp. 738-745
-
-
Alexander, G.E.1
Chen, K.2
Pietrini, P.3
Rapoport, S.I.4
Reiman, E.M.5
-
69
-
-
0018647771
-
Metabolic mapping of functional activity in the hypothalamo-neurohypophysial system of the rat
-
Schwartz WJ, Smith CB, Davidsen L, Savaki H, Sokoloff L, Mata M, et al. Metabolic mapping of functional activity in the hypothalamo-neurohypophysial system of the rat. Science 205(4407): 723-725 (1979).
-
(1979)
Science
, vol.205
, Issue.4407
, pp. 723-725
-
-
Schwartz, W.J.1
Smith, C.B.2
Davidsen, L.3
Savaki, H.4
Sokoloff, L.5
Mata, M.6
-
70
-
-
0034784359
-
An energy budget for signaling in the grey matter of the brain
-
Attwell D, Laughlin SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab 21(10): 1133-1145 (2001).
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, Issue.10
, pp. 1133-1145
-
-
Attwell, D.1
Laughlin, S.B.2
-
71
-
-
1842295295
-
Differential effects of electrical stimulation of sciatic nerve on metabolic activity in spinal cord and dorsal root ganglion in the rat
-
Kadekaro M, Crane AM, Sokoloff L. Differential effects of electrical stimulation of sciatic nerve on metabolic activity in spinal cord and dorsal root ganglion in the rat. Proc Natl Acad Sci USA 82(17): 6010-6013 (1985).
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, Issue.17
, pp. 6010-6013
-
-
Kadekaro, M.1
Crane, A.M.2
Sokoloff, L.3
-
72
-
-
0344552488
-
Restingstate brain glucose utilization as measured by PET is directly related to regional synaptophysin levels: A study in baboons
-
Rocher AB, Chapon F, Blaizot X, Baron JC, Chavoix C. Restingstate brain glucose utilization as measured by PET is directly related to regional synaptophysin levels: a study in baboons. Neuroimage 20(3): 1894-1898 (2003).
-
(2003)
Neuroimage
, vol.20
, Issue.3
, pp. 1894-1898
-
-
Rocher, A.B.1
Chapon, F.2
Blaizot, X.3
Baron, J.C.4
Chavoix, C.5
-
73
-
-
17844364259
-
Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease
-
Mosconi L. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. Eur J Nucl Med Mol Imaging 32(4): 486-510 (2005).
-
(2005)
Eur J Nucl Med Mol Imaging
, vol.32
, Issue.4
, pp. 486-510
-
-
Mosconi, L.1
-
74
-
-
0023737618
-
Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type?
-
Hoyer S, Oesterreich K, Wagner O. Glucose metabolism as the site of the primary abnormality in early-onset dementia of Alzheimer type? J Neurol 235(3): 143-8 (1988).
-
(1988)
J Neurol
, vol.235
, Issue.3
, pp. 143-148
-
-
Hoyer, S.1
Oesterreich, K.2
Wagner, O.3
-
75
-
-
0036205701
-
The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: An update
-
Hoyer S. The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: an update.J Neural Transm 109(3): 341-60 (2002).
-
(2002)
J Neural Transm
, vol.109
, Issue.3
, pp. 341-360
-
-
Hoyer, S.1
-
76
-
-
84939941724
-
The metabolism hypothesis of Alzheimer's disease: From the concept of central insulin resistance and associated consequences to insulin therapy
-
Morgen K, Frolich L. The metabolism hypothesis of Alzheimer's disease: from the concept of central insulin resistance and associated consequences to insulin therapy. J Neural Transm 122(4): 499-504 (2015).
-
(2015)
J Neural Transm
, vol.122
, Issue.4
, pp. 499-504
-
-
Morgen, K.1
Frolich, L.2
-
77
-
-
67349213205
-
Synaptic degeneration in Alzheimer's disease
-
Arendt T. Synaptic degeneration in Alzheimer's disease. Acta Neuropathol 118(1): 167-179 (2009).
-
(2009)
Acta Neuropathol
, vol.118
, Issue.1
, pp. 167-179
-
-
Arendt, T.1
-
78
-
-
33747760358
-
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
-
Scheff SW, Price DA, Schmitt FA, Mufson EJ. Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment. Neurobiol Aging 27(10): 1372-1384 (2006).
-
(2006)
Neurobiol Aging
, vol.27
, Issue.10
, pp. 1372-1384
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
Mufson, E.J.4
-
79
-
-
34247611481
-
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
-
Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology 68(18): 1501-1508 (2007).
-
(2007)
Neurology
, vol.68
, Issue.18
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
DeKosky, S.T.4
Mufson, E.J.5
-
80
-
-
0018078940
-
Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia
-
Perry EK, Tomlinson BE, Blessed G, Bergmann K, Gibson PH, Perry RH. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. Br Med J 2(6150): 1457-1459 (1978).
-
(1978)
Br Med J
, vol.2
, Issue.6150
, pp. 1457-1459
-
-
Perry, E.K.1
Tomlinson, B.E.2
Blessed, G.3
Bergmann, K.4
Gibson, P.H.5
Perry, R.H.6
-
81
-
-
20944438631
-
Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease
-
Bohnen NI, Kaufer DI, Hendrickson R, Ivanco LS, Lopresti BJ, Constantine GM, et al. Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease. Neurosci Lett 380(1-2): 127-132 (2005).
-
(2005)
Neurosci Lett
, vol.380
, Issue.1-2
, pp. 127-132
-
-
Bohnen, N.I.1
Kaufer, D.I.2
Hendrickson, R.3
Ivanco, L.S.4
Lopresti, B.J.5
Constantine, G.M.6
-
82
-
-
0033541026
-
In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease
-
Kuhl DE, Koeppe RA, Minoshima S, Snyder SE, Ficaro EP, Foster NL, et al. In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease. Neurol 52(4): 691-699 (1999).
-
(1999)
Neurol
, vol.52
, Issue.4
, pp. 691-699
-
-
Kuhl, D.E.1
Koeppe, R.A.2
Minoshima, S.3
Snyder, S.E.4
Ficaro, E.P.5
Foster, N.L.6
-
83
-
-
84882329428
-
Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load
-
Alkalay A, Rabinovici GD, Zimmerman G, Agarwal N, Kaufer D, Miller BL, et al. Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load. Curr Alzheimer Res 10(1): 48-56 (2013).
-
(2013)
Curr Alzheimer Res
, vol.10
, Issue.1
, pp. 48-56
-
-
Alkalay, A.1
Rabinovici, G.D.2
Zimmerman, G.3
Agarwal, N.4
Kaufer, D.5
Miller, B.L.6
-
84
-
-
64049118355
-
Hippocampal atrophy rates in Alzheimer disease: Added value over whole brain volume measures
-
Henneman WJ, Sluimer JD, Barnes J, van der Flier WM, Sluimer IC, Fox NC, et al. Hippocampal atrophy rates in Alzheimer disease: added value over whole brain volume measures. Neurology 72(11): 999-1007 (2009).
-
(2009)
Neurology
, vol.72
, Issue.11
, pp. 999-1007
-
-
Henneman, W.J.1
Sluimer, J.D.2
Barnes, J.3
van der Flier, W.M.4
Sluimer, I.C.5
Fox, N.C.6
-
85
-
-
66249125569
-
A meta-analysis of hippocampal atrophy rates in Alzheimer's disease
-
Barnes J, Bartlett JW, van de Pol LA, Loy CT, Scahill RI, Frost C, et al. A meta-analysis of hippocampal atrophy rates in Alzheimer's disease. Neurobiol Aging 30(11): 1711-1723 (2009).
-
(2009)
Neurobiol Aging
, vol.30
, Issue.11
, pp. 1711-1723
-
-
Barnes, J.1
Bartlett, J.W.2
van de Pol, L.A.3
Loy, C.T.4
Scahill, R.I.5
Frost, C.6
-
86
-
-
33750594921
-
Tracking atrophy progression in familial Alzheimer's disease: A serial MRI study
-
Ridha BH, Barnes J, Bartlett JW, Godbolt A, Pepple T, Rossor MN, et al. Tracking atrophy progression in familial Alzheimer's disease: a serial MRI study. Lancet Neurol 5(10): 828-834 (2006).
-
(2006)
Lancet Neurol
, vol.5
, Issue.10
, pp. 828-834
-
-
Ridha, B.H.1
Barnes, J.2
Bartlett, J.W.3
Godbolt, A.4
Pepple, T.5
Rossor, M.N.6
-
87
-
-
84856966847
-
Structural MRI changes detectable up to ten years before clinical Alzheimer's disease
-
Tondelli M, Wilcock GK, Nichelli P, De Jager CA, Jenkinson M, Zamboni G. Structural MRI changes detectable up to ten years before clinical Alzheimer's disease. Neurobiol Aging 33(4): 825.e25-825.e36 (2012).
-
(2012)
Neurobiol Aging
, vol.33
, Issue.4
, pp. 825.e25-825.e36
-
-
Tondelli, M.1
Wilcock, G.K.2
Nichelli, P.3
De Jager, C.A.4
Jenkinson, M.5
Zamboni, G.6
-
88
-
-
59749096829
-
The cortical signature of Alzheimer's disease: Regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloidpositive individuals
-
Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloidpositive individuals. Cereb Cortex 19(3): 497-510 (2009).
-
(2009)
Cereb Cortex
, vol.19
, Issue.3
, pp. 497-510
-
-
Dickerson, B.C.1
Bakkour, A.2
Salat, D.H.3
Feczko, E.4
Pacheco, J.5
Greve, D.N.6
-
89
-
-
70350327167
-
Diffusion tensor imaging in Alzheimer's disease and mild cognitive impairment
-
Stebbins GT, Murphy CM. Diffusion tensor imaging in Alzheimer's disease and mild cognitive impairment. Behav Neurol 21(1): 39-49 (2009).
-
(2009)
Behav Neurol
, vol.21
, Issue.1
, pp. 39-49
-
-
Stebbins, G.T.1
Murphy, C.M.2
-
90
-
-
78049283756
-
Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network
-
Harris JA, Devidze N, Verret L, Ho K, Halabisky B, Thwin MT, et al. Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron 68: 428-441 (2010).
-
(2010)
Neuron
, vol.68
, pp. 428-441
-
-
Harris, J.A.1
Devidze, N.2
Verret, L.3
Ho, K.4
Halabisky, B.5
Thwin, M.T.6
-
91
-
-
41949121294
-
The brain's default network: Anatomy, function, and relevance to disease
-
Buckner RL, Andrews-Hanna JR, Schacter DL. The brain's default network: anatomy, function, and relevance to disease. Ann NY Acad Sci 1124: 1-38 (2008).
-
(2008)
Ann NY Acad Sci
, vol.1124
, pp. 1-38
-
-
Buckner, R.L.1
Andrews-Hanna, J.R.2
Schacter, D.L.3
-
92
-
-
67650875899
-
Amyloid deposition is associated with impaired default network function in older persons without dementia
-
Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 63(2): 178-188 (2009).
-
(2009)
Neuron
, vol.63
, Issue.2
, pp. 178-188
-
-
Sperling, R.A.1
Laviolette, P.S.2
O'Keefe, K.3
O'Brien, J.4
Rentz, D.M.5
Pihlajamaki, M.6
-
93
-
-
1842427969
-
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI
-
Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci USA 101(13): 4637-4642 (2004).
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.13
, pp. 4637-4642
-
-
Greicius, M.D.1
Srivastava, G.2
Reiss, A.L.3
Menon, V.4
-
94
-
-
35148890661
-
Altered functional connectivity in early Alzheimer's disease: A resting-state fMRI study
-
Wang K, Liang M, Wang L, Tian L, Zhang X, Li K, et al. Altered functional connectivity in early Alzheimer's disease: a resting-state fMRI study. Hum Brain Map 28: 967-78 (2007).
-
(2007)
Hum Brain Map
, vol.28
, pp. 967-978
-
-
Wang, K.1
Liang, M.2
Wang, L.3
Tian, L.4
Zhang, X.5
Li, K.6
-
95
-
-
46249131887
-
Network analysis of intrinsic functional brain connectivity in Alzheimer's disease
-
Supekar K, Menon V, Rubin D, Musen M, Greicius MD. Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Comput Biol 4(6): e1000100 (2008).
-
(2008)
PLoS Comput Biol
, vol.4
, Issue.6
-
-
Supekar, K.1
Menon, V.2
Rubin, D.3
Musen, M.4
Greicius, M.D.5
-
96
-
-
84904323428
-
Altered effective connectivity patterns of the default mode network in Alzheimer's disease: An fMRI study
-
Zhong Y, Huang L, Cai S, Zhang Y, von Deneen KM, Ren A, et al.Altered effective connectivity patterns of the default mode network in Alzheimer's disease: an fMRI study. Neurosci Lett 578: 171-5 (2014).
-
(2014)
Neurosci Lett
, vol.578
, pp. 171-175
-
-
Zhong, Y.1
Huang, L.2
Cai, S.3
Zhang, Y.4
von Deneen, K.M.5
Ren, A.6
-
97
-
-
79960965577
-
Relationships between beta-amyloid and functional connectivity in different components of the default mode network in aging
-
Mormino EC, Smiljic A, Hayenga AO, Onami SH, Greicius MD, Rabinovici GD, et al. Relationships between beta-amyloid and functional connectivity in different components of the default mode network in aging. Cereb Cortex 21(10): 2399-2407 (2011).
-
(2011)
Cereb Cortex
, vol.21
, Issue.10
, pp. 2399-2407
-
-
Mormino, E.C.1
Smiljic, A.2
Hayenga, A.O.3
Onami, S.H.4
Greicius, M.D.5
Rabinovici, G.D.6
|