The trafficking of NaV1.8

Neuroscience Letters

Volumn 486, Issue 2, 2010, Pages 78-83

  Swanwick, Richard S ^a   Pristerá, Alessandro ^a   Okuse, Kenji ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Pain; Sensory Neuron; Sodium Channel; Trafficking

Indexed keywords

CONTACTIN; PDZ PROTEIN; PDZD2 PROTEIN; PROSTAGLANDIN E2; PROTEIN; PROTEIN CAP 1A; PROTEIN P110; SODIUM CHANNEL NAV1.8; UNCLASSIFIED DRUG;

CELL MEMBRANE; CELL MIGRATION; ENDOPLASMIC RETICULUM; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANNEXIN A2; CELL MEMBRANE; CONTACTINS; DINOPROSTONE; ENDOPLASMIC RETICULUM; HUMANS; MICE; NERVE TISSUE PROTEINS; PROTEIN SUBUNITS; PROTEIN TRANSPORT; S100 PROTEINS; SODIUM CHANNELS;

EID: 78049400253     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.08.074     Document Type: Review

References (54)

1. Akopian A.N., Souslova V., England S., Okuse K., Ogata N., Ure J., Smith A., Kerr B.J., McMahon S.B., Boyce S., Hill R., Stanfa L.C., Dickenson A.H., Wood J.N. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat. Neurosci. 1999, 2(6):541-548.
2. 2+-regulated association of lipid microdomains. J. Cell Biol. 2000, 150(5):1113-1123.
3. Baker M.D., Poon W.-Y.L., Wood J.N., Okuse K. Functional effects of co-transfecting β-subunits 1, 1A and 3 with NaV1. 8 α-subunit in a COS-7 heterologous system. J. Physiol. 2004, 555P:PC20.
4. Bramham C.R., Messaoudi E. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog. Neurobiol. 2005, 76(2):99-125.
5. Chambers J.C., Zhao J., Terracciano C.M., Bezzina C.R., Zhang W., Kaba R., Navaratnarajah M., Lotlikar A., Sehmi J.S., Kooner M.K., Deng G., Siedlecka U., Parasramka S., El-Hamamsy I., Wass M.N., Dekker L.R., de Jong J.S., Sternberg M.J., McKenna W., Severs N.J., de Silva R., Wilde A.A., Anand P., Yacoub M., Scott J., Elliott P., Wood J.N., Kooner J.S. Genetic variation in SCN10A influences cardiac conduction. Nat. Genet. 2010, 42(2):149-152.
6. Choi J.S., Hudmon A., Waxman S.G., Dib-Hajj S.D. Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons. J. Neurophysiol. 2006, 96:97-108.
7. Fitzgerald E.M., Okuse K., Wood J.N., Dolphin A.C., Moss S.J. cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS. J. Physiol. 1999, 516(Pt 2):433-446.
8. Foulkes T., Nassar M.A., Lane T., Matthews E.A., Baker M.D., Gerke V., Okuse K., Dickenson A.H., Wood J.N. Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behaviour. J. Neurosci. 2006, 26(41):10499-10507.
9. Gaida W., Klinder K., Arndt K., Weiser T. Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain. Neuropharmacology 2005, 49(8):1220-1227.
10. Garrido J.J., Fernandes F., Giraud P., Mouret I., Pasqualini E., Fache M.P., Jullien F., Dargent B. Identification of an axonal determinant in the C-terminus of the sodium channel Na(v)1.2. EMBO J. 2001, 20(21):5950-5961.
11. Gassmann M., Haller C., Stoll Y., Aziz S.A., Biermann B., Mosbacher J., Kaupmann K., Bettler B. The RXR-type endoplasmic reticulum-retention/retrieval signal of GABAB1 requires distant spacing from the membrane to function. Mol. Pharmacol. 2005, 68(1):137-144.
12. + channel, TASK-1. EMBO J. 2002, 21(17):4439-4448.
13. Gu Y, Gu C. Dynamics of Kv1 channel transport in axons. PLoS One 2010, 5(8):e11931.
14. Iijima T., Imai T., Kimura Y., Bernstein A., Okano H.J., Yuzaki M., Okano H. Hzf protein regulates dendritic localization an BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA. Proc. Natl. Acad. Sci. U. S. A. 2005, 102(47):17190-17195.
15. Jarvis M.F., Honore P., Shieh C.C., Chapman M., Joshi S., Zhang X.F., Kort M., Carroll W., Marron B., Atkinson R., Thomas J., Liu D., Krambis M., Liu Y., McGaraughty S., Chu K., Roeloffs R., Zhong C., Mikusa J.P., Hernandez G., Gauvin D., Wade C., Zhu C., Pai M., Scanio M., Shi L., Drizin I., Gregg R., Matulenko M., Hakeem A., Gross M., Johnson M., Marsh K., Wagoner P.K., Sullivan J.P., Faltynek C.R., Krafte D.S. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc. Natl. Acad. Sci. U. S. A. 2007, 104(20):8520-8525.
16. Jiménez-Díaz L., Géranton S.M., Passmore G.M., Leith J.L., Fisher A.S., Berliocchi L., Sivasubramaniam A.K., Sheasby A., Lumb B.M., Hunt S.P. Local translation in primary afferent fibers regulates nociception. PLoS One 2008, 3(4):e1961.
17. Johnsson N, Weber K. Alkylation of cysteine 82 of p11 abolishes the complex formation with the tyrosine-protein kinase substrate p36 (annexin 2, calpactin 2, lipocortin 2). J. Biol. Chem. 1990, 265:14464-14468.
18. Johnsson N., Marriott G., Weber K. p36, the major cytoplasmic substrate of src tyrosine protein kinase, binds to its p11 regulatory subunit via a short amino-terminal amphipathic helix. EMBO J. 1988, 7(8):2435-2442.
19. Jost M., Gerke V. Mapping of a regulatory important site for protein kinase C phosphorylation in the N-terminal domain of annexin II. Biochim. Biophys. Acta 1996, 1313(3):283-289.
20. + channels and increases their functional expression. J. Neurosci. 2001, 21(19):7517-7525.
21. Kim E., Sheng M. PDZ domain proteins of synapses. Nat. Rev. Neurosci. 2004, 5(10):771-781.
22. König J., Prenen J., Nilius B., Gerke V. The annexin II-p11 complex is involved in regulated exocytosis in bovine pulmonary artery endothelial cells. J. Biol. Chem. 1998, 273(31):19679-19684.
23. Lai J., Gold M.S., Kim C.S., Bian D., Ossipov M.H., Hunter J.C., Porreca F. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel NaV1.8. Pain 2002, 95(1-2):143-152.
24. Lin C.R., Amaya F., Barrett L., Wang H., Takada J., Samad T.A., Woolf C.J. Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity. J. Pharmacol. Exp. Ther. 2006, 319(3):1096-1103.
25. Liu C., Cummins T.R., Tyrrell L., Black J.A., Waxman S.G., Dib-Hajj S.D. AP-1A is a novel linker that binds clathrin and the voltage-gated sodium channel Na(v)1.8. Mol. Cell. Neurosci. 2005, 28(4):636-649.
26. Liu C., Li Q., Su Y., Bao L. Prostaglandin E2 promotes Nav1.8 trafficking via its intracellular RRR motif through the protein kinase A pathway. Traffic 2010, 11(3):405-417.
27. McEwen D.P., Meadows l.S., Chen C., Thyagarajan V., Isom L.L. Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin. J. Biol. Chem. 2004, 279(16):16044-16049.
28. Macara I.G., Iioka H., Mili S. Axon growth-stimulus package includes local translation. Nat. Cell. Biol. 2009, 11(8):919-921.
29. V1.8. Brain Res. Mol. Brain Res. 2003, 110(2):298-304.
30. Okuse K. Pain signalling pathways: from cytokines to ion channels. Int. J. Biochem. Cell Biol. 2007, 39(3):490-496.
31. Okuse K., Malik-Hall M., Baker M.D., Poon W.-Y.L., Kong H., Chao M.V., Wood J.N. Annexin II light chain regulates sensory neuron-specific sodium channel expression. Nature 2002, 417(6889):653-656.
32. Poon W.-Y.L., Malik-Hall M., Wood J.N., Okuse K. Identification of binding domains in the sodium channel Na(V)1.8 intracellular N-terminal region and annexin II light chain p11. FEBS Lett. 2004, 558(1-3):114-118.
33. Rescher U., Gerke V. S100A10/p11: family, friends and functions. Pflugers Arch. 2008, 455(4):575-582.
34. Renigunta V., Yuan H., Zuzarte M., Rinné S., Koch A., Wischmeyer E., Schlichthörl G., Gao Y., Karschin A., Jacob R., Schwappach B., Daut J., Preisig-Müller R. The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1. Traffic 2006, 7(2):168-181.
35. Ritchie J.M., Black J.A., Waxman S.G., Angelides K.J. Sodium channels in the cytoplasm of Schwann Cells. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:9290-9294.
36. Rush A.M., Craner M.J., Kageyama T., Dib-Hajj S.D., Waxman S.G., Ranscht B. Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons. Eur. J. Neurosci. 2005, 22(1):39-49.
37. Saris C.J., Kristensen T., D'Eustachio P., Hicks L.J., Noonan D.J., Hunter T., Tack B.F. cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (Calpactin I). J. Biol. Chem. 1987, 262:10663-10671.
38. Schmidt J.W, Catterall W.A. Biosynthesis and processing of the alpha subunit of the voltage-sensitive sodium channel in rat brain neurons. Cell 1986, 46(3):437-444.
39. Scott D.B., Blanpied T.A., Swanson G.T., Zhang C., Ehlers M.D. An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing. J. Neurosci. 2001, 21(9):3063-3072.
40. Shah B.S., Stevens E.B., Gonzalez M.I., Bramwell S., Pinnock R.D., Lee K., Dixon A.K. Beta3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain. Eur. J. Neurosci. 2000, 12(11):3985-3990.
41. Shah B.S., Gonzalez M.I., Bramwell S., Pinnock R.D., Lee K., Dixon A.K. Beta3, a novel auxiliary subunit for the voltage gated sodium channel is upregulated in sensory neurones following streptozocin induced diabetic neuropathy in rat. Neurosci. Lett. 2001, 309(1):1-4.
42. Shah B.S., Rush A.M., Liu S., Tyrrell L., Black J.A., Dib-Hajj S.D., Waxman S.G. Contactin associates with sodium channel Nav1.3 in native tissues and increases channel density at the cell surface. J. Neurosci. 2004, 24(33):7387-7399.
43. Shao D., Baker M.D., Abrahamsen B., Rugiero F., Malik-Hall M., Poon W.-Y.L., Cheah K.S., Yao K.M., Wood J.N., Okuse K. A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8. Mol. Cell Neurosci. 2009, 42(3):219-225.
44. Shao D., Okuse K., Djamgoz M.B. Protein-protein interactions involving voltage-gated sodium channels: Post-translational regulation, intracellular trafficking and functional expression. Int. J. Biochem. Cell Biol. 2009, 41(7):1471-1481.
45. Smith W.B., Starck S.R., Roberts R.W., Schuman E.M. Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons. Neuron 2005, 45(5):765-779.
46. Storey N., Latchman D., Bevan S. Selective internalization of sodium channels in rat dorsal root ganglion neurons infected with herpes simplex virus-1. J. Cell Biol. 2002, 158(7):1251-1262.
47. Takahashi N., Kikuchi S., Dai Y., Kobayashi K., Fukuoka T., Noguchi K. Expression of auxiliary beta subunits of sodium channels in primary afferent neurons and the effect of nerve injury. Neuroscience 2003, 121(2):441-450.
48. Taylor C.P. Mechanisms of analgesia by gabapentin and pregabalin--calcium channel alpha2-delta [Cavalpha2-delta] ligands. Pain 2009, 142(1-2):13-16.
49. V1.8 mRNA up-regulation in painful neuropathy. Mol. Pain 2009, 5:14.
50. Wang D.O., Kim S.M., Zhao Y., Hwang H., Miura S.K., Sossin W.S., Martin K.C. Synapse- and stimulus-specific local translation during long-term neuronal plasticity. Science 2009, 324(5934):1534-1536.
51. Yeung M.L., Tam T.S., Tsang A.C., Yao K.M. Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains. EMBO Rep. 2003, 4(4):412-418.
52. Zerangue N., Schwappach B., Jan Y.N., Jan L.Y. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. Neuron 1999, 22(3):537-548.
53. + channel Nav1.8 contains an ER-retention/retrieval signal antagonized by the beta3 subunit. J. Cell Sci. 2008, 121(Pt 19):3243-3252.
54. Zimmer D.B., Chaplin J., Baldwin A., Rast M. S100-mediated signal transduction in the nervous system and neurological diseases. Cell. Mol. Biol. 2005, 51(2):201-214.