메뉴 건너뛰기




Volumn 1351, Issue 1, 2015, Pages 127-140

The complex contribution of chemokines to neuroinflammation: Switching from beneficial to detrimental effects

Author keywords

Central nervous system; Chemokines; CNS disorders; Neuroinflammation; Neuromodulation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; FRACTALKINE; MONOCYTE CHEMOTACTIC PROTEIN 1; STROMAL CELL DERIVED FACTOR 1; AUTACOID;

EID: 84941805980     PISSN: 00778923     EISSN: 17496632     Source Type: Journal    
DOI: 10.1111/nyas.12855     Document Type: Article
Times cited : (81)

References (79)
  • 1
    • 0036319505 scopus 로고    scopus 로고
    • Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain
    • Banisadr, G., F. Queraud-Lesaux, M.C. Boutterin, et al. 2002. Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain. J. Neurochem. 81: 257-269.
    • (2002) J. Neurochem. , vol.81 , pp. 257-269
    • Banisadr, G.1    Queraud-Lesaux, F.2    Boutterin, M.C.3
  • 2
    • 0034537408 scopus 로고    scopus 로고
    • Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia
    • van der Meer, P., A.M. Ulrich, F. Gonzalez-Scarano, et al. 2000. Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Exp. Mol. Pathol. 69: 192-201.
    • (2000) Exp. Mol. Pathol. , vol.69 , pp. 192-201
    • van der Meer, P.1    Ulrich, A.M.2    Gonzalez-Scarano, F.3
  • 3
    • 28844433347 scopus 로고    scopus 로고
    • Are chemokines the third major system in the brain?
    • Adler, M.W. & T.J. Rogers 2005. Are chemokines the third major system in the brain? J. Leukoc. Biol. 78: 1204-1209.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 1204-1209
    • Adler, M.W.1    Rogers, T.J.2
  • 4
    • 80051789712 scopus 로고    scopus 로고
    • Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system
    • Rostene, W., M.A. Dansereau, D. Godefroy, et al. 2011. Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system. J. Neurochem. 118: 680-694.
    • (2011) J. Neurochem. , vol.118 , pp. 680-694
    • Rostene, W.1    Dansereau, M.A.2    Godefroy, D.3
  • 5
    • 14944386532 scopus 로고    scopus 로고
    • Complex effects of stromal cell-derived factor-1 alpha on melanin-concentrating hormone neuron excitability
    • Guyon, A., G. Banisadr, C. Rovere, et al. 2005. Complex effects of stromal cell-derived factor-1 alpha on melanin-concentrating hormone neuron excitability. Eur. J. Neurosci. 21: 701-710.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 701-710
    • Guyon, A.1    Banisadr, G.2    Rovere, C.3
  • 6
    • 14944338800 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells
    • Guyon, A., C. Rovere, A. Cervantes, et al. 2005. Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells. J. Neurochem. 93: 963-973.
    • (2005) J. Neurochem. , vol.93 , pp. 963-973
    • Guyon, A.1    Rovere, C.2    Cervantes, A.3
  • 7
    • 33744492850 scopus 로고    scopus 로고
    • The chemokine SDF-1/CXCL12 modulates the firing pattern of vasopressin neurons and counteracts induced vasopressin release through CXCR4
    • Callewaere, C., G. Banisadr, M.G. Desarmenien, et al. 2006. The chemokine SDF-1/CXCL12 modulates the firing pattern of vasopressin neurons and counteracts induced vasopressin release through CXCR4. Proc. Natl. Acad. Sci. U.S.A. 103: 8221-8226.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 8221-8226
    • Callewaere, C.1    Banisadr, G.2    Desarmenien, M.G.3
  • 8
    • 78651432549 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: new actors in neuroendocrine regulations
    • Rostene, W., A. Guyon, L. Kular, et al. 2011. Chemokines and chemokine receptors: new actors in neuroendocrine regulations. Front. Neuroendocrinol. 32: 10-24.
    • (2011) Front. Neuroendocrinol. , vol.32 , pp. 10-24
    • Rostene, W.1    Guyon, A.2    Kular, L.3
  • 9
    • 32144454172 scopus 로고    scopus 로고
    • The many roles of chemokines and chemokine receptors in inflammation
    • Charo, I.F. & R.M. Ransohoff 2006. The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 354: 610-621.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 610-621
    • Charo, I.F.1    Ransohoff, R.M.2
  • 11
    • 0842324615 scopus 로고    scopus 로고
    • Chemokines: multiple levels of leukocyte migration control
    • Moser, B., M. Wolf, A. Walz, et al. 2004. Chemokines: multiple levels of leukocyte migration control. Trends Immunol. 25: 75-84.
    • (2004) Trends Immunol. , vol.25 , pp. 75-84
    • Moser, B.1    Wolf, M.2    Walz, A.3
  • 12
    • 84861426163 scopus 로고    scopus 로고
    • The chemokine superfamily revisited
    • Zlotnik, A. & O. Yoshie 2012. The chemokine superfamily revisited. Immunity 36: 705-716.
    • (2012) Immunity , vol.36 , pp. 705-716
    • Zlotnik, A.1    Yoshie, O.2
  • 13
    • 50849085193 scopus 로고    scopus 로고
    • Chemokines in and out of the central nervous system: much more than chemotaxis and inflammation
    • Cardona, A.E., M. Li, L. Liu, et al. 2008. Chemokines in and out of the central nervous system: much more than chemotaxis and inflammation. J. Leukoc. Biol. 84: 587-594.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 587-594
    • Cardona, A.E.1    Li, M.2    Liu, L.3
  • 15
    • 84887355961 scopus 로고    scopus 로고
    • Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway
    • Apostolakis, S. & D. Spandidos 2013. Chemokines and atherosclerosis: focus on the CX3CL1/CX3CR1 pathway. Acta Pharmacol. Sin. 34: 1251-1256.
    • (2013) Acta Pharmacol. Sin. , vol.34 , pp. 1251-1256
    • Apostolakis, S.1    Spandidos, D.2
  • 16
    • 84897478440 scopus 로고    scopus 로고
    • Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage
    • Sheridan, G.K. & K.J. Murphy 2013. Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage. Open Biol. 3: 130181.
    • (2013) Open Biol. , vol.3 , pp. 130181
    • Sheridan, G.K.1    Murphy, K.J.2
  • 17
    • 0036682239 scopus 로고    scopus 로고
    • Fractalkine and fractalkine receptors in human neurons and glial cells
    • Hatori, K., A. Nagai, R. Heisel, et al. 2002. Fractalkine and fractalkine receptors in human neurons and glial cells. J. Neurosci. Res. 69: 418-426.
    • (2002) J. Neurosci. Res. , vol.69 , pp. 418-426
    • Hatori, K.1    Nagai, A.2    Heisel, R.3
  • 18
    • 84867796425 scopus 로고    scopus 로고
    • Deficiency of the microglial receptor CX3CR1 impairs postnatal functional development of thalamocortical synapses in the barrel cortex
    • Hoshiko, M., I. Arnoux, E. Avignone, et al. 2012. Deficiency of the microglial receptor CX3CR1 impairs postnatal functional development of thalamocortical synapses in the barrel cortex. J. Neurosci. 32: 15106-15111.
    • (2012) J. Neurosci. , vol.32 , pp. 15106-15111
    • Hoshiko, M.1    Arnoux, I.2    Avignone, E.3
  • 19
    • 66149172257 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1): an overview
    • Deshmane, S.L., S. Kremlev, S. Amini, et al. 2009. Monocyte chemoattractant protein-1 (MCP-1): an overview. J. Interferon Cytokine Res. 29: 313-326.
    • (2009) J. Interferon Cytokine Res. , vol.29 , pp. 313-326
    • Deshmane, S.L.1    Kremlev, S.2    Amini, S.3
  • 20
    • 22644444838 scopus 로고    scopus 로고
    • Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides
    • Banisadr, G., R.D. Gosselin, P. Mechighel, et al. 2005. Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides. J. Comp. Neurol. 489: 275-292.
    • (2005) J. Comp. Neurol. , vol.489 , pp. 275-292
    • Banisadr, G.1    Gosselin, R.D.2    Mechighel, P.3
  • 21
    • 18344407347 scopus 로고    scopus 로고
    • Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons
    • Coughlan, C.M., C.M. McManus, M. Sharron, et al. 2000. Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience 97: 591-600.
    • (2000) Neuroscience , vol.97 , pp. 591-600
    • Coughlan, C.M.1    McManus, C.M.2    Sharron, M.3
  • 22
    • 0344958804 scopus 로고    scopus 로고
    • Developmental expression of monocyte chemoattractant protein-1 in the human cerebellum and brainstem
    • Meng, S.Z., A. Oka & S. Takashima 1999. Developmental expression of monocyte chemoattractant protein-1 in the human cerebellum and brainstem. Brain Dev. 21: 30-35.
    • (1999) Brain Dev , vol.21 , pp. 30-35
    • Meng, S.Z.1    Oka, A.2    Takashima, S.3
  • 23
    • 0141705319 scopus 로고    scopus 로고
    • Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons
    • Banisadr, G., D. Skrzydelski, P. Kitabgi, et al. 2003. Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur. J. Neurosci. 18: 1593-1606.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1593-1606
    • Banisadr, G.1    Skrzydelski, D.2    Kitabgi, P.3
  • 24
    • 84865865940 scopus 로고    scopus 로고
    • Cellular and subcellular localization of CXCL12 and CXCR4 in rat nociceptive structures: physiological relevance
    • Reaux-Le Goazigo, A., C. Rivat, P. Kitabgi, et al. 2012. Cellular and subcellular localization of CXCL12 and CXCR4 in rat nociceptive structures: physiological relevance. Eur. J. Neurosci. 36: 2619-2631.
    • (2012) Eur. J. Neurosci. , vol.36 , pp. 2619-2631
    • Reaux-Le Goazigo, A.1    Rivat, C.2    Kitabgi, P.3
  • 25
    • 84875266578 scopus 로고    scopus 로고
    • CNS sterile injury: just another wound healing?
    • Shechter, R. & M. Schwartz 2013. CNS sterile injury: just another wound healing? Trends Mol. Med. 19: 135-143.
    • (2013) Trends Mol. Med. , vol.19 , pp. 135-143
    • Shechter, R.1    Schwartz, M.2
  • 26
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl, U., C. Iadecola & M.A. Moskowitz 1999. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 22: 391-397.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 27
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
    • Jin, R., G. Yang & G. Li 2010. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J. Leukoc. Biol. 87: 779-789.
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 779-789
    • Jin, R.1    Yang, G.2    Li, G.3
  • 28
    • 0036228047 scopus 로고    scopus 로고
    • Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury
    • Soriano, S.G., L.S. Amaravadi, Y.F. Wang, et al. 2002. Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury. J. Neuroimmunol. 125: 59-65.
    • (2002) J. Neuroimmunol. , vol.125 , pp. 59-65
    • Soriano, S.G.1    Amaravadi, L.S.2    Wang, Y.F.3
  • 29
    • 52549109505 scopus 로고    scopus 로고
    • Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse
    • Denes, A., S. Ferenczi, J. Halasz, et al. 2008. Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse. J. Cereb. Blood Flow Metab. 28: 1707-1721.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1707-1721
    • Denes, A.1    Ferenczi, S.2    Halasz, J.3
  • 30
    • 80755127243 scopus 로고    scopus 로고
    • CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents
    • Cipriani, R., P. Villa, G. Chece, et al. 2011. CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents. J. Neurosci. 31: 16327-16335.
    • (2011) J. Neurosci. , vol.31 , pp. 16327-16335
    • Cipriani, R.1    Villa, P.2    Chece, G.3
  • 31
    • 84895445357 scopus 로고    scopus 로고
    • CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke
    • Tang, Z., Y. Gan, Q. Liu, et al. 2014. CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke. J. Neuroinflammation 11: 26.
    • (2014) J. Neuroinflammation , vol.11 , pp. 26
    • Tang, Z.1    Gan, Y.2    Liu, Q.3
  • 32
    • 84904192139 scopus 로고    scopus 로고
    • Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death
    • Rosito, M., C. Lauro, G. Chece, et al. 2014. Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death. Front. Cell. Neurosci. 8: 193.
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 193
    • Rosito, M.1    Lauro, C.2    Chece, G.3
  • 33
    • 84880447854 scopus 로고    scopus 로고
    • Evidence for a gender-specific protective role of innate immune receptors in a model of perinatal brain injury
    • Pimentel-Coelho, P.M., J.P. Michaud & S. Rivest 2013. Evidence for a gender-specific protective role of innate immune receptors in a model of perinatal brain injury. J. Neurosci. 33: 11556-11572.
    • (2013) J. Neurosci. , vol.33 , pp. 11556-11572
    • Pimentel-Coelho, P.M.1    Michaud, J.P.2    Rivest, S.3
  • 34
    • 84865583063 scopus 로고    scopus 로고
    • Higher plasma fractalkine is associated with better 6-month outcome from ischemic stroke
    • Donohue, M.M., K. Cain, D. Zierath, et al. 2012. Higher plasma fractalkine is associated with better 6-month outcome from ischemic stroke. Stroke 43: 2300-2306.
    • (2012) Stroke , vol.43 , pp. 2300-2306
    • Donohue, M.M.1    Cain, K.2    Zierath, D.3
  • 35
    • 0034721572 scopus 로고    scopus 로고
    • K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection
    • Blondeau, N., H. Plamondon, C. Richelme, et al. 2000. K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection. Neuroscience 100: 465-474.
    • (2000) Neuroscience , vol.100 , pp. 465-474
    • Blondeau, N.1    Plamondon, H.2    Richelme, C.3
  • 36
    • 84937558922 scopus 로고    scopus 로고
    • Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation
    • Lauro, C., M. Catalano, E. Di Paolo, et al. 2014. Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation. Front. Cell. Neurosci. 8: 472.
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 472
    • Lauro, C.1    Catalano, M.2    Di Paolo, E.3
  • 37
    • 23044464868 scopus 로고    scopus 로고
    • Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity
    • Limatola, C., C. Lauro, M. Catalano, et al. 2005. Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity. J. Neuroimmunol. 166: 19-28.
    • (2005) J. Neuroimmunol. , vol.166 , pp. 19-28
    • Limatola, C.1    Lauro, C.2    Catalano, M.3
  • 38
    • 0028826503 scopus 로고
    • Induced expression of adhesion molecules following focal brain ischemia
    • Wang, X. & G.Z. Feuerstein 1995. Induced expression of adhesion molecules following focal brain ischemia. J. Neurotrauma. 12: 825-832.
    • (1995) J. Neurotrauma. , vol.12 , pp. 825-832
    • Wang, X.1    Feuerstein, G.Z.2
  • 39
    • 0035368670 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 expressed in neurons and astrocytes during focal ischemia in mice
    • Che, X., W. Ye, L. Panga, et al. 2001. Monocyte chemoattractant protein-1 expressed in neurons and astrocytes during focal ischemia in mice. Brain Res. 902: 171-177.
    • (2001) Brain Res. , vol.902 , pp. 171-177
    • Che, X.1    Ye, W.2    Panga, L.3
  • 40
    • 0037085719 scopus 로고    scopus 로고
    • Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS
    • Hughes, P.M., M.S. Botham, S. Frentzel, et al. 2002. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS. Glia 37: 314-327.
    • (2002) Glia , vol.37 , pp. 314-327
    • Hughes, P.M.1    Botham, M.S.2    Frentzel, S.3
  • 41
    • 33745712943 scopus 로고    scopus 로고
    • Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury
    • Dimitrijevic, O.B., S.M. Stamatovic, R.F. Keep, et al. 2006. Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury. J. Cereb. Blood Flow Metab. 26: 797-810.
    • (2006) J. Cereb. Blood Flow Metab. , vol.26 , pp. 797-810
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3
  • 42
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic, O.B., S.M. Stamatovic, R.F. Keep, et al. 2007. Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke 38: 1345-1353.
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3
  • 43
    • 68649107955 scopus 로고    scopus 로고
    • The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice
    • Schilling, M., J.K. Strecker, E.B. Ringelstein, et al. 2009. The role of CC chemokine receptor 2 on microglia activation and blood-borne cell recruitment after transient focal cerebral ischemia in mice. Brain Res. 1289: 79-84.
    • (2009) Brain Res , vol.1289 , pp. 79-84
    • Schilling, M.1    Strecker, J.K.2    Ringelstein, E.B.3
  • 44
    • 84880555465 scopus 로고    scopus 로고
    • Effects of radiation combined injury on hippocampal function are modulated in mice deficient in chemokine receptor 2 (CCR2)
    • Allen, A.R., K. Eilertson, S. Sharma, et al. 2013. Effects of radiation combined injury on hippocampal function are modulated in mice deficient in chemokine receptor 2 (CCR2). Radiat. Res. 180: 78-88.
    • (2013) Radiat. Res. , vol.180 , pp. 78-88
    • Allen, A.R.1    Eilertson, K.2    Sharma, S.3
  • 45
    • 84884500989 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1-deficiency results in altered blood-brain barrier breakdown after experimental stroke
    • Strecker, J.K., J. Minnerup, K. Schutte-Nutgen, et al. 2013. Monocyte chemoattractant protein-1-deficiency results in altered blood-brain barrier breakdown after experimental stroke. Stroke 44: 2536-2544.
    • (2013) Stroke , vol.44 , pp. 2536-2544
    • Strecker, J.K.1    Minnerup, J.2    Schutte-Nutgen, K.3
  • 46
    • 34547395911 scopus 로고    scopus 로고
    • Chemokine ligand 2 (CCL2) induces migration and differentiation of subventricular zone cells after stroke
    • Liu, X.S., Z.G. Zhang, R.L. Zhang, et al. 2007. Chemokine ligand 2 (CCL2) induces migration and differentiation of subventricular zone cells after stroke. J. Neurosci. Res. 85: 2120-2125.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2120-2125
    • Liu, X.S.1    Zhang, Z.G.2    Zhang, R.L.3
  • 47
    • 84862744891 scopus 로고    scopus 로고
    • Macrophages prevent hemorrhagic infarct transformation in murine stroke models
    • Gliem, M., A.K. Mausberg, J.I. Lee, et al. 2012. Macrophages prevent hemorrhagic infarct transformation in murine stroke models. Ann. Neurol. 71: 743-752.
    • (2012) Ann. Neurol. , vol.71 , pp. 743-752
    • Gliem, M.1    Mausberg, A.K.2    Lee, J.I.3
  • 48
    • 84872074957 scopus 로고    scopus 로고
    • CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice
    • Huang, J., Y. Li, Y. Tang, et al. 2013. CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice. Stroke 44: 190-197.
    • (2013) Stroke , vol.44 , pp. 190-197
    • Huang, J.1    Li, Y.2    Tang, Y.3
  • 49
    • 84881121382 scopus 로고    scopus 로고
    • Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke
    • Ruscher, K., E. Kuric, Y. Liu, et al. 2013. Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke. J. Cereb. Blood Flow Metab. 33: 1225-1234.
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , pp. 1225-1234
    • Ruscher, K.1    Kuric, E.2    Liu, Y.3
  • 50
    • 84901916903 scopus 로고    scopus 로고
    • Postacute stromal cell-derived factor-1alpha expression promotes neurovascular recovery in ischemic mice
    • Li, Y., J. Huang, X. He, et al. 2014. Postacute stromal cell-derived factor-1alpha expression promotes neurovascular recovery in ischemic mice. Stroke 45: 1822-1829.
    • (2014) Stroke , vol.45 , pp. 1822-1829
    • Li, Y.1    Huang, J.2    He, X.3
  • 51
    • 84899061596 scopus 로고    scopus 로고
    • Endogenous endothelial progenitor cells participate in neovascularization via CXCR4/SDF-1 axis and improve outcome after stroke
    • Mao, L., M. Huang, S.C. Chen, et al. 2014. Endogenous endothelial progenitor cells participate in neovascularization via CXCR4/SDF-1 axis and improve outcome after stroke. CNS Neurosci. Ther. 20: 460-468.
    • (2014) CNS Neurosci. Ther , vol.20 , pp. 460-468
    • Mao, L.1    Huang, M.2    Chen, S.C.3
  • 52
    • 84904292341 scopus 로고    scopus 로고
    • Ischemic brain extract increases SDF-1 expression in astrocytes through the CXCR2/miR-223/miR-27b pathway
    • Shin, J.H., Y.M. Park, D.H. Kim, et al. 2014. Ischemic brain extract increases SDF-1 expression in astrocytes through the CXCR2/miR-223/miR-27b pathway. Biochim. Biophys. Acta 1839: 826-836.
    • (2014) Biochim. Biophys. Acta , vol.1839 , pp. 826-836
    • Shin, J.H.1    Park, Y.M.2    Kim, D.H.3
  • 53
    • 84929921146 scopus 로고    scopus 로고
    • Immune attack: the role of inflammation in Alzheimer disease
    • Heppner, F.L., R.M. Ransohoff & B. Becher 2015. Immune attack: the role of inflammation in Alzheimer disease. Nat. Rev. Neurosci. 16: 358-372.
    • (2015) Nat. Rev. Neurosci. , vol.16 , pp. 358-372
    • Heppner, F.L.1    Ransohoff, R.M.2    Becher, B.3
  • 54
    • 77957316313 scopus 로고    scopus 로고
    • CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models
    • Lee, S., N.H. Varvel, M.E. Konerth, et al. 2010. CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models. Am. J. Pathol. 177: 2549-2562.
    • (2010) Am. J. Pathol. , vol.177 , pp. 2549-2562
    • Lee, S.1    Varvel, N.H.2    Konerth, M.E.3
  • 55
    • 80052714655 scopus 로고    scopus 로고
    • CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease
    • Cho, S.H., B. Sun, Y. Zhou, et al. 2011. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. J. Biol. Chem. 286: 32713-32722.
    • (2011) J. Biol. Chem. , vol.286 , pp. 32713-32722
    • Cho, S.H.1    Sun, B.2    Zhou, Y.3
  • 56
    • 84907015837 scopus 로고    scopus 로고
    • Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway
    • Lee, S., G. Xu, T.R. Jay, et al. 2014. Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway. J. Neurosci. 34: 12538-12546.
    • (2014) J. Neurosci. , vol.34 , pp. 12538-12546
    • Lee, S.1    Xu, G.2    Jay, T.R.3
  • 57
    • 84875247375 scopus 로고    scopus 로고
    • Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy
    • Nash, K.R., D.C. Lee, J.B. Hunt, Jr., et al. 2013. Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy. Neurobiol. Aging 34: 1540-1548.
    • (2013) Neurobiol. Aging , vol.34 , pp. 1540-1548
    • Nash, K.R.1    Lee, D.C.2    Hunt Jr, J.B.3
  • 58
    • 41949125406 scopus 로고    scopus 로고
    • Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease
    • Kim, T.S., H.K. Lim, J.Y. Lee, et al. 2008. Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease. Neurosci. Lett. 436: 196-200.
    • (2008) Neurosci. Lett. , vol.436 , pp. 196-200
    • Kim, T.S.1    Lim, H.K.2    Lee, J.Y.3
  • 59
    • 84937468720 scopus 로고    scopus 로고
    • Changes in the expression of genes related to neuroinflammation over the course of sporadic Alzheimer's disease progression: CX3CL1, TREM2, and PPARγ
    • Strobel, S., E. Grunblatt, P. Riederer, et al. 2015. Changes in the expression of genes related to neuroinflammation over the course of sporadic Alzheimer's disease progression: CX3CL1, TREM2, and PPARγ. J. Neural Transm. 122: 1069-1076.
    • (2015) J. Neural Transm. , vol.122 , pp. 1069-1076
    • Strobel, S.1    Grunblatt, E.2    Riederer, P.3
  • 60
    • 0030988629 scopus 로고    scopus 로고
    • Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease
    • Ishizuka, K., T. Kimura, R. Igata-yi, et al. 1997. Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease. Psychiatry Clin. Neurosci. 51: 135-138.
    • (1997) Psychiatry Clin. Neurosci. , vol.51 , pp. 135-138
    • Ishizuka, K.1    Kimura, T.2    Igata-yi, R.3
  • 61
    • 0035690770 scopus 로고    scopus 로고
    • Inflammatory factors are elevated in brain microvessels in Alzheimer's disease
    • Grammas, P. & R. Ovase 2001. Inflammatory factors are elevated in brain microvessels in Alzheimer's disease. Neurobiol. Aging 22: 837-842.
    • (2001) Neurobiol. Aging , vol.22 , pp. 837-842
    • Grammas, P.1    Ovase, R.2
  • 62
    • 84885356418 scopus 로고    scopus 로고
    • + monocytes: the hidden side of Alzheimer's disease
    • + monocytes: the hidden side of Alzheimer's disease. J. Mol. Cell. Biol. 5: 284-293.
    • (2013) J. Mol. Cell. Biol. , vol.5 , pp. 284-293
    • Naert, G.1    Rivest, S.2
  • 63
    • 0036277146 scopus 로고    scopus 로고
    • Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes
    • Smits, H.A., A. Rijsmus, J.H. vanLoon, et al. 2002. Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes. J. Neuroimmunol. 127: 160-168.
    • (2002) J. Neuroimmunol. , vol.127 , pp. 160-168
    • Smits, H.A.1    Rijsmus, A.2    van Loon, J.H.3
  • 64
    • 0030210955 scopus 로고    scopus 로고
    • Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells
    • Meda, L., S. Bernasconi, C. Bonaiuto, et al. 1996. Beta-amyloid (25-35) peptide and IFN-gamma synergistically induce the production of the chemotactic cytokine MCP-1/JE in monocytes and microglial cells. J. Immunol. 157: 1213-1218.
    • (1996) J. Immunol. , vol.157 , pp. 1213-1218
    • Meda, L.1    Bernasconi, S.2    Bonaiuto, C.3
  • 65
    • 0038204838 scopus 로고    scopus 로고
    • CD36 mediates the innate host response to beta-amyloid
    • El Khoury, J.B., K.J. Moore, T.K. Means, et al. 2003. CD36 mediates the innate host response to beta-amyloid. J. Exp. Med. 197: 1657-1666.
    • (2003) J. Exp. Med. , vol.197 , pp. 1657-1666
    • El Khoury, J.B.1    Moore, K.J.2    Means, T.K.3
  • 66
    • 62249200515 scopus 로고    scopus 로고
    • Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway
    • Vukic, V., D. Callaghan, D. Walker, et al. 2009. Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiol. Dis. 34: 95-106.
    • (2009) Neurobiol. Dis. , vol.34 , pp. 95-106
    • Vukic, V.1    Callaghan, D.2    Walker, D.3
  • 67
    • 0033276630 scopus 로고    scopus 로고
    • CXC and CC chemokine receptors on coronary and brain endothelia
    • Berger, O., X. Gan, C. Gujuluva, et al. 1999. CXC and CC chemokine receptors on coronary and brain endothelia. Mol. Med. 5: 795-805.
    • (1999) Mol. Med , vol.5 , pp. 795-805
    • Berger, O.1    Gan, X.2    Gujuluva, C.3
  • 68
    • 84864436756 scopus 로고    scopus 로고
    • CCL2 disrupts the adherens junction: implications for neuroinflammation
    • Roberts, T.K., E.A. Eugenin, L. Lopez, et al. 2012. CCL2 disrupts the adherens junction: implications for neuroinflammation. Lab. Invest. 92: 1213-1233.
    • (2012) Lab. Invest. , vol.92 , pp. 1213-1233
    • Roberts, T.K.1    Eugenin, E.A.2    Lopez, L.3
  • 69
    • 33749998363 scopus 로고    scopus 로고
    • Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease
    • Galimberti, D., C. Fenoglio, C. Lovati, et al. 2006. Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease. Neurobiol. Aging 27: 1763-1768.
    • (2006) Neurobiol. Aging , vol.27 , pp. 1763-1768
    • Galimberti, D.1    Fenoglio, C.2    Lovati, C.3
  • 70
    • 33645731581 scopus 로고    scopus 로고
    • Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease
    • Galimberti, D., N. Schoonenboom, P. Scheltens, et al. 2006. Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease. Arch. Neurol. 63: 538-543.
    • (2006) Arch. Neurol. , vol.63 , pp. 538-543
    • Galimberti, D.1    Schoonenboom, N.2    Scheltens, P.3
  • 71
    • 84872354623 scopus 로고    scopus 로고
    • CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease
    • Kiyota, T., H.E. Gendelman, R.A. Weir, et al. 2013. CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease. Neurobiol. Aging 34: 1060-1068.
    • (2013) Neurobiol. Aging , vol.34 , pp. 1060-1068
    • Kiyota, T.1    Gendelman, H.E.2    Weir, R.A.3
  • 72
    • 34147115541 scopus 로고    scopus 로고
    • Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
    • El Khoury, J., M. Toft, S.E. Hickman, et al. 2007. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat. Med. 13: 432-438.
    • (2007) Nat. Med. , vol.13 , pp. 432-438
    • El Khoury, J.1    Toft, M.2    Hickman, S.E.3
  • 73
    • 33846640591 scopus 로고    scopus 로고
    • Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues
    • Weeraratna, A.T., A. Kalehua, I. Deleon, et al. 2007. Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues. Exp. Cell Res. 313: 450-461.
    • (2007) Exp. Cell Res. , vol.313 , pp. 450-461
    • Weeraratna, A.T.1    Kalehua, A.2    Deleon, I.3
  • 74
    • 35349020900 scopus 로고    scopus 로고
    • Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
    • Parachikova, A. & C.W. Cotman 2007. Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease. Neurobiol. Dis. 28: 143-153.
    • (2007) Neurobiol. Dis. , vol.28 , pp. 143-153
    • Parachikova, A.1    Cotman, C.W.2
  • 75
    • 57349143819 scopus 로고    scopus 로고
    • Decreased plasma and cerebrospinal fluid levels of stem cell factor in patients with early Alzheimer's disease
    • Laske, C., K. Stellos, E. Stransky, et al. 2008. Decreased plasma and cerebrospinal fluid levels of stem cell factor in patients with early Alzheimer's disease. J. Alzheimers Dis. 15: 451-460.
    • (2008) J. Alzheimers Dis , vol.15 , pp. 451-460
    • Laske, C.1    Stellos, K.2    Stransky, E.3
  • 76
    • 80855148191 scopus 로고    scopus 로고
    • Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1alpha, suppress amyloid beta-induced neurotoxicity
    • Raman, D., S.Z. Milatovic, D. Milatovic, et al. 2011. Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1alpha, suppress amyloid beta-induced neurotoxicity. Toxicol. Appl. Pharmacol. 256: 300-313.
    • (2011) Toxicol. Appl. Pharmacol. , vol.256 , pp. 300-313
    • Raman, D.1    Milatovic, S.Z.2    Milatovic, D.3
  • 77
    • 84861230070 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1alpha decreases beta-amyloid deposition in Alzheimer's disease mouse model
    • Wang, Q., Y. Xu, J.C. Chen, et al. 2012. Stromal cell-derived factor 1alpha decreases beta-amyloid deposition in Alzheimer's disease mouse model. Brain Res. 1459: 15-26.
    • (2012) Brain Res. , vol.1459 , pp. 15-26
    • Wang, Q.1    Xu, Y.2    Chen, J.C.3
  • 78
    • 68049123116 scopus 로고    scopus 로고
    • Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release
    • Guyon, A., D. Skrzydelski, I. DeGiry, et al. 2009. Long term exposure to the chemokine CCL2 activates the nigrostriatal dopamine system: a novel mechanism for the control of dopamine release. Neuroscience 162: 1072-1080.
    • (2009) Neuroscience , vol.162 , pp. 1072-1080
    • Guyon, A.1    Skrzydelski, D.2    De Giry, I.3
  • 79
    • 84941806104 scopus 로고    scopus 로고
    • The chemokine MCP1 mediates inflammation-induced anorexia through its action on hypothalamic MCH neurons
    • Presented at 11ème Colloque de la Société des Neurosciences, Lyon, France, 21-24 May 2014.
    • Le Thuc, O., N. Blondeau, W. Rostène, et al. 2013. The chemokine MCP1 mediates inflammation-induced anorexia through its action on hypothalamic MCH neurons. Presented at 11ème Colloque de la Société des Neurosciences, Lyon, France, 21-24 May 2014.
    • (2013)
    • Le Thuc, O.1    Blondeau, N.2    Rostène, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.