Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity

Journal of Neuroimmunology

Volumn 166, Issue 1-2, 2005, Pages 19-28

  Limatola, Cristina ^a,b,e   Lauro, Clotilde ^a   Catalano, Myriam ^a   Ciotti, Maria Teresa ^c   Bertollini, Cristina ^a   Di Angelantonio, Silvia ^a,b   Ragozzino, Davide ^a,b   Eusebi, Fabrizio ^a,d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

^c CNR   (Italy)

^d IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^e Istituto di Fisiologia Umana e Farmacologia   (Italy)

Author keywords

AMPA current; ERK1 2; Fractalkine; Glutamate; Neuroprotection; PI3K Akt

Indexed keywords

FRACTALKINE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMINO ACID RECEPTOR STIMULATING AGENT; CHEMOKINE (C X3 C MOTIF) LIGAND 1; CHEMOKINE (C-X3-C MOTIF) LIGAND 1; CX3C CHEMOKINE; MEMBRANE PROTEIN; NEUROPROTECTIVE AGENT; NEUROTOXIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CENTRAL NERVOUS SYSTEM DISEASE; CHRONIC DISEASE; CONTROLLED STUDY; ENZYME ACTIVATION; EXCITOTOXICITY; HIPPOCAMPUS; HUMAN; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CELL SURVIVAL; DRUG ADMINISTRATION; DRUG COMBINATION; DRUG EFFECT; ELECTRIC CONDUCTIVITY; METABOLISM; NERVE CELL; PHYSIOLOGY; WISTAR RAT;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CHEMOKINES, CX3C; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; ELECTRIC CONDUCTIVITY; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; HIPPOCAMPUS; MEMBRANE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, WISTAR;

EID: 23044464868     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2005.03.023     Document Type: Article

References (42)

1. M. Ankarcrona, J.M. Dypbukt, E. Bonfoco, B. Zhivotovsky, S. Orrenius, S.A. Lipton, and P. Nicotera Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function Neuron 15 1995 961 973
2. D.M. Araujo, and C.W. Cotman Trophic effects of interleukin-4, -7 and -8 on hippocampal neuronal cultures: potential involvement of glial-derived factors Brain Res. 600 1993 49 55
3. V.C. Asensio, and I.L. Campbell Chemokines in the CNS: plurifunctional mediators in diverse states Trends Neurosci. 22 1999 504 512
4. 3C motif Nature 385 1997 640 644
5. S.A. Boehme, F.M. Lio, D. Maciejewski-Lenoir, K.B. Bacon, and P.J. Conlon The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia J. Immunol. 165 2000 397 403
6. V. Bruno, A. Copani, G. Besong, G. Scoto, and F. Nicoletti Neuroprotective activity of chemokines against N-methyl-d-aspartate or beta-amyloid-induced toxicity in culture Eur. J. Pharmacol. 399 2000 117 121
7. G.A. Chapman, K. Moores, D. Harrison, C.A. Campbell, B.R. Steward, and P.J.L.M. Strijbos Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage J. Neurosci. 20 2000 RC87
8. D.W. Choi Glutamate neurotoxicity and diseases of the nervous system Neuron 1 1988 623 634
9. K. Deiva, T. Geeraerts, H. Salim, P. Leclerc, C. Héry, B. Hugel, J.-M. Freyssinet, and M. Tardieu Fractalkine reduces N-methyl-d-aspartate- induced calcium flux and apoptosis in human neurons through extracellular signal-regulated kinase activation Eur. J. Neurosci. 20 2004 3222 3232
10. C.R. Elliott-Hunt, J. Kazlauskaite, G.J.C. Wilde, D.K. Grammatopoulos, and E.W. Hillhouse Potential signalling pathways underlying corticotrophin- releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus J. Neurochem. 80 2002 416 425
11. D. Erichsen, A.L. Lopez, H. Peng, D. Niemann, C. Williams, M. Bauer, S. Morgello, R.L. Cotter, L.A. Ryan, A. Ghorpade, H.E. Gendelman, and J. Zheng Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia J. Neuroimmunol. 138 2003 144 155
12. E.A. Eugenin, T.G. D'Aversa, L. Lopez, T.M. Calderon, and J.W. Berman MCP-1 (CCL2) protects human neurons and astrocytes from NMDA or HIV-tat-induced apoptosis J. Neurochem. 85 2003 1299 1311
13. P. Fraticelli, M. Sironi, G. Bianchi, D. D'Ambrosio, C. Albanesi, A. Stoppacciaro, M. Chieppa, P. Allavena, L. Ruco, G. Girolomoni, F. Sinigaglia, A. Vecchi, and A. Mantovani J. Clin. Invest. 107 2001 1173 1181
14. S.E. Gillard, M. Lu, R.M. Mastracci, and R.J. Miller Expression of functional chemokine receptors by rat cerebellar neurons J. Neuroimmunol. 124 2002 16 28
15. J.K. Harrison, Y. Jiang, S. Chen, Y. Xia, D. Maciejewski, R.K. McNamara, W.J. Streit, M.N. Salafranca, S. Adhikari, and D.A. Thompson Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia Proc. Natl. Acad. Sci. U. S. A. 95 1998 10896 10901
16. K. Hatori, A. Nagai, R. Heisel, J.K. Ryu, and S.U. Kim Fractalkine and fractalkine receptors in human neurons and glial cells J. Neurosci. Res. 69 2002 418 426
17. T.W. Ho, L.A. Bristol, C. Coccia, Y. Li, J. Milbrandt, E. Johnson, L. Jin, O. Bar-Peled, J.W. Griffin, and J.D. Rothstein TGFbeta trophic factors differentially modulate motor axon outgrow and protection from excitotoxicity Exp. Neurol. 161 2000 664 675
18. P.M. Hughes, M.S. Botham, S. Frentzel, A. Mir, and V.H. Perry Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS Glia 37 2002 314 327
19. C. Hundhausen, D. Misztela, T.A. Berkhout, N. Broadway, P. Saftig, K. Reiss, D. Hartmann, F. Fahrenholz, R. Postina, V. Matthews, K.-J. Kallen, S. Rose-John, and A. Ludwig The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion Blood 102 2003 1186 1195
20. Y. Jiang, M.N. Salafranca, S. Adhikari, Y. Xia, L. Feng, M.K. Sonntag, C.M. deFiebre, N.A. Pennel, W.J. Streit, and J.K. Harrison Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis J. Neuroimmunol. 86 1998 1 12
21. 3CL1) in inflammatory disease of the nervous system J. Neuroimmunol. 137 2003 210 217
22. M.D. Krathwohl, and J.L. Kaiser Chemokines promote quiescence and survival of human neural progenitor cells Stem Cells 22 2004 109 118
23. C. Limatola, M.T. Ciotti, D. Mercanti, F. Vacca, D. Ragozzino, A. Giovannelli, A. Santoni, F. Eusebi, and R. Miledi The chemokine growth-related gene product β protects rat cerebellar granule cells from apoptotic cell death through α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors Proc. Natl. Acad. Sci. U. S. A. 97 2000 6197 7201
24. M. Lu, E.A. Grove, and R.J. Miller Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor Proc. Natl. Acad. Sci. U. S. A. 99 2002 7090 7095
25. A. Ludwig, T. Berkhout, K. Moores, P. Groot, and G. Chapman Fractalkine is expressed by smooth muscle cells in response to IFN-gamma and TND-alpha and is modulated by metalloproteinase activity J. Immunol. 168 2002 604 612
26. Q. Ma, D. Jones, P.R. Borghesani, R.A. Segal, T. Nagasawa, T. Kishimoto, R.T. Bronson, and T.A. Springer Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice Proc. Natl. Acad. Sci. U. S. A. 95 1998 9448 9453
27. D. Maciejewski-Lenoir, S. Chen, L. Feng, R. Maki, and K.B. Bacon Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia J. Immunol. 163 1999 1628 1635
28. O. Meucci, A. Fatatis, A.A. Simen, T.J. Bushell, P.W. Gray, and R.J. Miller Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity Proc. Natl. Acad. Sci. U. S. A. 95 1998 14500 14505
29. O. Meucci, A. Fatatis, A.A. Simen, and R.J. Miller Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival Proc. Natl. Acad. Sci. U. S. A. 97 2000 8075 8080
30. T. Mizuno, J. Kawanokuchi, K. Numata, and A. Suzumura Production and neuroprotective functions of fractalkine in the central nervous system Brain Res. 979 2003 65 70
31. P. Nicotera, M. Leist, and L. Manzo Neuronal cell death: a demise with different shapes Trends Pharmacol. Sci. 20 1999 46 51
32. C.F. Pereira, J. Middel, G. Jansen, J. Verhoef, and H.S. Nottel Enhanced expression of fractalkine in HIV-1 associated dementia J. Neuroimmunol. 115 2001 168 175
33. S. Robinson, M. Tani, R.M. Strieter, R.M. Ransohoff, and R.H. Miller The chemokine growth-related oncogene-α promotes spinal cord oligodendrocytes precursor proliferation J. Neurosci. 18 1998 10457 10463
34. C.A. Singer, X.A. Figueroa-Masot, R.H. Batchelor, and D.M. Dorsa The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons J. Neurosci. 19 1999 2455 2463
35. S.G. Soriano, L.S. Amaravadi, Y.F. Wang, H. Zhou, G.X. Yu, J.R. Tonra, V. Fairchild-Huntress, Q. Fang, J.H. Dunmore, D. Huszar, and Y. Pan Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury J. Neuroimmunol. 125 2002 59 65
36. G. Tarozzo, M. Campanella, M. Ghiani, A. Bulfone, and M. Beltramo Expression of fractalkine and its receptor CX3CR1, in response to ischaemia-reperfusion brain injury in the rat Eur. J. Neurosci. 15 2002 1663 1668
37. N. Tong, S.W. Perry, Q. Zhang, H.J. James, H. Guo, A. Brooks, H. Bal, S.A. Kinnear, S. Fine, L.G. Epstein, D. Dairaghi, T.J. Schall, H.E. Gendelman, S. Dewhurst, L.R. Sharer, and H.A. Gelbard Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system J. Immunol. 164 2000 1333 1339
38. P.B. Tran, and R.J. Miller Chemokine receptors: signposts to brain development and disease Nat. Rev., Neurosci. 4 2003 444 455
39. C. Volontè, M.T. Ciotti, and L. Battistini Development of a method for measuring cell number: application to CNS primary neuronal cultures Cytometry 17 1994 274 276
40. H. Yoshida, T. Imaizumi, K. Fujimoto, N. Matsuo, K. Kimura, X. Cui, T. Matsumija, K. Tanji, T. Shibata, W. Tamo, M. Kumagai, and K. Satoh Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes Neurosci. Lett. 303 2001 132 136
41. Y.R. Zou, A.H. Kottmann, M. Kuroda, I. Taniuchi, and D.R. Littman Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development Nature 393 1998 595 599
42. V. Zujovic, J. Benavides, X. Vige, C. Carter, and V. Taupin Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation Glia 29 2000 305 315