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Volumn 33, Issue 8, 2013, Pages 1225-1234

Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke

Author keywords

brain ischemia; chemokine; enriched environment; inflammation; regeneration and recovery; T cells

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; PLERIXAFOR; SODIUM CHLORIDE; STROMAL CELL DERIVED FACTOR 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84881121382     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.71     Document Type: Article
Times cited : (92)

References (40)
  • 1
    • 84871578644 scopus 로고    scopus 로고
    • Stroke rehabilitation: Recent advances and future therapies
    • Brewer L, Horgan F, Hickey A, Williams D. Stroke rehabilitation: recent advances and future therapies. QJM 2012; 106: 11-25.
    • (2012) QJM , vol.106 , pp. 11-25
    • Brewer, L.1    Horgan, F.2    Hickey, A.3    Williams, D.4
  • 2
    • 80755172317 scopus 로고    scopus 로고
    • The use of non-invasive brain stimulation techniques to facilitate recovery from post-stroke aphasia
    • Schlaug G, Marchina S, Wan CY. The use of non-invasive brain stimulation techniques to facilitate recovery from post-stroke aphasia. Neuropsychol Rev 2011; 21: 288-301.
    • (2011) Neuropsychol Rev , vol.21 , pp. 288-301
    • Schlaug, G.1    Marchina, S.2    Wan, C.Y.3
  • 3
    • 0035828396 scopus 로고    scopus 로고
    • Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: A prospective, randomised, double-blind study
    • Scheidtmann K, Fries W, Muller F, Koenig E. Effect of levodopa in combination with physiotherapy on functional motor recovery after stroke: a prospective, randomised, double-blind study. Lancet 2001; 358: 787-790.
    • (2001) Lancet , vol.358 , pp. 787-790
    • Scheidtmann, K.1    Fries, W.2    Muller, F.3    Koenig, E.4
  • 4
    • 78149476696 scopus 로고    scopus 로고
    • Removing brakes on adult brain plasticity: From molecular to behavioral interventions
    • Bavelier D, Levi DM, Li RW, Dan Y, Hensch TK. Removing brakes on adult brain plasticity: from molecular to behavioral interventions. J Neurosci 2010; 30: 14964-14971.
    • (2010) J Neurosci , vol.30 , pp. 14964-14971
    • Bavelier, D.1    Levi, D.M.2    Li, R.W.3    Dan, Y.4    Hensch, T.K.5
  • 5
    • 33745478859 scopus 로고    scopus 로고
    • Mechanisms of neural plasticity following brain injury
    • Wieloch T, Nikolich K. Mechanisms of neural plasticity following brain injury. Curr Opin Neurobiol 2006; 16: 258-264.
    • (2006) Curr Opin Neurobiol , vol.16 , pp. 258-264
    • Wieloch, T.1    Nikolich, K.2
  • 6
    • 64549132610 scopus 로고    scopus 로고
    • Live imaging of Tolllike receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation
    • Lalancette-Hebert M, Phaneuf D, Soucy G, Weng YC, Kriz J. Live imaging of Tolllike receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation. Brain 2009; 132: 940-954.
    • (2009) Brain , vol.132 , pp. 940-954
    • Lalancette-Hebert, M.1    Phaneuf, D.2    Soucy, G.3    Weng, Y.C.4    Kriz, J.5
  • 7
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas SM, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. Br J Pharmacol 2006; 147(Suppl 1): S232-S240.
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 8
    • 0042886941 scopus 로고    scopus 로고
    • Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation
    • Prass K, Meisel C, Hoflich C, Braun J, Halle E, Wolf T et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med 2003; 198: 725-736.
    • (2003) J Exp Med , vol.198 , pp. 725-736
    • Prass, K.1    Meisel, C.2    Hoflich, C.3    Braun, J.4    Halle, E.5    Wolf, T.6
  • 9
    • 59349116941 scopus 로고    scopus 로고
    • Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression
    • Offner H, Vandenbark AA, Hurn PD. Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression. Neuroscience 2009; 158: 1098-1111.
    • (2009) Neuroscience , vol.158 , pp. 1098-1111
    • Offner, H.1    Vandenbark, A.A.2    Hurn, P.D.3
  • 11
    • 67349166480 scopus 로고    scopus 로고
    • Behavioral immunization: Immunity to self-antigens contributes to psychological stress resilience
    • Lewitus GM, Schwartz M. Behavioral immunization: immunity to self-antigens contributes to psychological stress resilience. Mol Psychiatry 2009; 14: 532-536.
    • (2009) Mol Psychiatry , vol.14 , pp. 532-536
    • Lewitus, G.M.1    Schwartz, M.2
  • 12
    • 84857194991 scopus 로고    scopus 로고
    • Environmental enrichment alters glial antigen expression and neuroimmune function in the adult rat hippocampus
    • Williamson LL, Chao A, Bilbo SD. Environmental enrichment alters glial antigen expression and neuroimmune function in the adult rat hippocampus. Brain Behav Immun 2012; 26: 500-510.
    • (2012) Brain Behav Immun , vol.26 , pp. 500-510
    • Williamson, L.L.1    Chao, A.2    Bilbo, S.D.3
  • 13
    • 39749176165 scopus 로고    scopus 로고
    • Apolipoprotein D is elevated in oligodendrocytes in the peri-infarct region after experimental stroke: Influence of enriched environment
    • Rickhag M, Deierborg T, Patel S, Ruscher K, Wieloch T. Apolipoprotein D is elevated in oligodendrocytes in the peri-infarct region after experimental stroke: influence of enriched environment. J Cereb Blood Flow Metab 2008; 28: 551-562.
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 551-562
    • Rickhag, M.1    Deierborg, T.2    Patel, S.3    Ruscher, K.4    Wieloch, T.5
  • 14
    • 71949089337 scopus 로고    scopus 로고
    • Enriched environment reduces apolipoprotein e (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke
    • Ruscher K, Johannesson E, Brugiere E, Erickson A, Rickhag M, Wieloch T. Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke. J Cereb Blood Flow Metab 2009; 29: 1796-1805.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1796-1805
    • Ruscher, K.1    Johannesson, E.2    Brugiere, E.3    Erickson, A.4    Rickhag, M.5    Wieloch, T.6
  • 15
    • 79952126094 scopus 로고    scopus 로고
    • The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke
    • Ruscher K, Shamloo M, Rickhag M, Ladunga I, Soriano L, Gisselsson L et al. The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke. Brain 2011; 134: 732-746.
    • (2011) Brain , vol.134 , pp. 732-746
    • Ruscher, K.1    Shamloo, M.2    Rickhag, M.3    Ladunga, I.4    Soriano, L.5    Gisselsson, L.6
  • 16
    • 0036139655 scopus 로고    scopus 로고
    • Neuronal plasticity and dendritic spines: Effect of environmental enrichment on intact and postischemic rat brain
    • Johansson BB, Belichenko PV. Neuronal plasticity and dendritic spines: effect of environmental enrichment on intact and postischemic rat brain. J Cereb Blood Flow Metab 2002; 22: 89-96.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 89-96
    • Johansson, B.B.1    Belichenko, P.V.2
  • 17
    • 33750945702 scopus 로고    scopus 로고
    • Enriched environment attenuates cell genesis in subventricular zone after focal ischemia in mice and decreases migration of newborn cells to the striatum
    • Nygren J, Wieloch T, Pesic J, Brundin P, Deierborg T. Enriched environment attenuates cell genesis in subventricular zone after focal ischemia in mice and decreases migration of newborn cells to the striatum. Stroke 2006; 37: 2824-2829.
    • (2006) Stroke , vol.37 , pp. 2824-2829
    • Nygren, J.1    Wieloch, T.2    Pesic, J.3    Brundin, P.4    Deierborg, T.5
  • 19
    • 47249149222 scopus 로고    scopus 로고
    • CXCR7, CXCR4 and CXCL12 an eccentric trio?
    • Thelen M, Thelen S. CXCR7, CXCR4 and CXCL12: an eccentric trio? J Neuroimmunol 2008; 198: 9-13.
    • (2008) J Neuroimmunol , vol.198 , pp. 9-13
    • Thelen, M.1    Thelen, S.2
  • 20
    • 84865854082 scopus 로고    scopus 로고
    • Chemokine CXCL12 and its receptors in the developing central nervous system: Emerging themes and future perspectives
    • Zhu Y, Murakami F. Chemokine CXCL12 and its receptors in the developing central nervous system: emerging themes and future perspectives. Dev Neurobiol 2012; 72: 1349-1362.
    • (2012) Dev Neurobiol , vol.72 , pp. 1349-1362
    • Zhu, Y.1    Murakami, F.2
  • 21
    • 78049469834 scopus 로고    scopus 로고
    • Distinctive properties of CXC chemokine receptor 4-expressing Cajal-Retzius cells versus GABAergic interneurons of the postnatal hippocampus
    • Marchionni I, Takács VT, Nunzi MG, Mugnaini E, Miller RJ, Maccaferri G. Distinctive properties of CXC chemokine receptor 4-expressing Cajal-Retzius cells versus GABAergic interneurons of the postnatal hippocampus. J Physiol 2010; 588: 2859-2878.
    • (2010) J Physiol , vol.588 , pp. 2859-2878
    • Marchionni, I.1    Takács, V.T.2    Nunzi, M.G.3    Mugnaini, E.4    Miller, R.J.5    MacCaferri, G.6
  • 22
    • 33747127567 scopus 로고    scopus 로고
    • Viewing chemokines as a third major system of communication in the brain
    • Adler MW, Geller EB, Chen X, Rogers TJ. Viewing chemokines as a third major system of communication in the brain. AAPS J 2005; 7: E865-E870.
    • (2005) AAPS J , vol.7
    • Adler, M.W.1    Geller, E.B.2    Chen, X.3    Rogers, T.J.4
  • 23
    • 33845656103 scopus 로고    scopus 로고
    • A neurovascular niche for neurogenesis after stroke
    • Ohab JJ, Fleming S, Blesch A, Carmichael ST. A neurovascular niche for neurogenesis after stroke. J Neurosci 2006; 26: 13007-13016.
    • (2006) J Neurosci , vol.26 , pp. 13007-13016
    • Ohab, J.J.1    Fleming, S.2    Blesch, A.3    Carmichael, S.T.4
  • 24
    • 9144261661 scopus 로고    scopus 로고
    • SDF-1 (CXCL12) is upregulated in the ischemic penumbra following stroke: Association with bone marrow cell homing to injury
    • Hill WD, Hess DC, Martin-Studdard A, Carothers JJ, Zheng J, Hale D et al. SDF-1 (CXCL12) is upregulated in the ischemic penumbra following stroke: association with bone marrow cell homing to injury. J Neuropathol Exp Neurol 2004; 63: 84-96.
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 84-96
    • Hill, W.D.1    Hess, D.C.2    Martin-Studdard, A.3    Carothers, J.J.4    Zheng, J.5    Hale, D.6
  • 25
    • 47249141913 scopus 로고    scopus 로고
    • Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain
    • Schonemeier B, Schulz S, Hoellt V, Stumm R. Enhanced expression of the CXCl12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain. J Neuroimmunol 2008; 198: 39-45.
    • (2008) J Neuroimmunol , vol.198 , pp. 39-45
    • Schonemeier, B.1    Schulz, S.2    Hoellt, V.3    Stumm, R.4
  • 26
    • 0036185087 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice
    • Blades MC, Ingegnoli F, Wheller SK, Manzo A, Wahid S, Panayi GS et al. Stromal cell-derived factor 1 (CXCL12) induces monocyte migration into human synovium transplanted onto SCID Mice. Arthritis Rheum 2002; 46: 824-836.
    • (2002) Arthritis Rheum , vol.46 , pp. 824-836
    • Blades, M.C.1    Ingegnoli, F.2    Wheller, S.K.3    Manzo, A.4    Wahid, S.5    Panayi, G.S.6
  • 27
    • 58149149835 scopus 로고    scopus 로고
    • CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells
    • Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N. CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. J Exp Med 2008; 205: 2643-2655.
    • (2008) J Exp Med , vol.205 , pp. 2643-2655
    • Meiron, M.1    Zohar, Y.2    Anunu, R.3    Wildbaum, G.4    Karin, N.5
  • 28
    • 49649103837 scopus 로고    scopus 로고
    • CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis
    • McCandless EE, Zhang B, Diamond MS, Klein RS. CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proc Natl Acad Sci USA 2008; 105: 11270-11275.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11270-11275
    • McCandless, E.E.1    Zhang, B.2    Diamond, M.S.3    Klein, R.S.4
  • 29
    • 0141923918 scopus 로고    scopus 로고
    • Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist
    • Liles WC, Broxmeyer HE, Rodger E, Wood B, Hubel K, Cooper S et al. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood 2003; 102: 2728-2730.
    • (2003) Blood , vol.102 , pp. 2728-2730
    • Liles, W.C.1    Broxmeyer, H.E.2    Rodger, E.3    Wood, B.4    Hubel, K.5    Cooper, S.6
  • 30
    • 78149253585 scopus 로고    scopus 로고
    • Acute anti-inflammatory approaches to ischemic stroke
    • del Zoppo GJ. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci 2010; 1207: 143-148.
    • (2010) Ann N y Acad Sci , vol.1207 , pp. 143-148
    • Del Zoppo, G.J.1
  • 31
    • 68349098877 scopus 로고    scopus 로고
    • Does inflammation after stroke affect the developing brain differently than adult brain?
    • Vexler ZS, Yenari MA. Does inflammation after stroke affect the developing brain differently than adult brain? Dev Neurosci 2009; 31: 378-393.
    • (2009) Dev Neurosci , vol.31 , pp. 378-393
    • Vexler, Z.S.1    Ma, Y.2
  • 32
    • 0037023216 scopus 로고    scopus 로고
    • The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice
    • Stevens SL, Bao J, Hollis J, Lessov NS, Clark WM, Stenzel-Poore MP. The use of flow cytometry to evaluate temporal changes in inflammatory cells following focal cerebral ischemia in mice. Brain Res 2002; 932: 110-119.
    • (2002) Brain Res , vol.932 , pp. 110-119
    • Stevens, S.L.1    Bao, J.2    Hollis, J.3    Lessov, N.S.4    Clark, W.M.5    Stenzel-Poore, M.P.6
  • 33
    • 34548680942 scopus 로고    scopus 로고
    • CD4(\+), CD25(-) effector T-cells inhibit hippocampal long-term potentiation in vitro
    • Lewitus GM, Zhu J, Xiong H, Hallworth R, Kipnis J. CD4(\+), CD25(-) effector T-cells inhibit hippocampal long-term potentiation in vitro. Eur J Neurosci 2007; 26: 1399-1406.
    • (2007) Eur J Neurosci , vol.26 , pp. 1399-1406
    • Lewitus, G.M.1    Zhu, J.2    Xiong, H.3    Hallworth, R.4    Kipnis, J.5
  • 34
    • 79958265647 scopus 로고    scopus 로고
    • Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke
    • Ren X, Akiyoshi K, Dziennis S, Vandenbark AA, Herson PS, Hurn PD et al. Regulatory B cells limit CNS inflammation and neurologic deficits in murine experimental stroke. J Neurosci 2011; 31: 8556-8563.
    • (2011) J Neurosci , vol.31 , pp. 8556-8563
    • Ren, X.1    Akiyoshi, K.2    Dziennis, S.3    Vandenbark, A.A.4    Herson, P.S.5    Hurn, P.D.6
  • 35
    • 84872074957 scopus 로고    scopus 로고
    • CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice
    • Huang J, Li Y, Tang Y, Tang G, Yang GY, Wang Y. CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice. Stroke 2012; 44: 190-197.
    • (2012) Stroke , vol.44 , pp. 190-197
    • Huang, J.1    Li, Y.2    Tang, Y.3    Tang, G.4    Yang, G.Y.5    Wang, Y.6
  • 37
    • 0034960228 scopus 로고    scopus 로고
    • CXCR4-activated astrocyte glutamate release via TNFalpha: Amplification by microglia triggers neurotoxicity
    • Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E et al. CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity. Nat Neurosci 2001; 4: 702-710.
    • (2001) Nat Neurosci , vol.4 , pp. 702-710
    • Bezzi, P.1    Domercq, M.2    Brambilla, L.3    Galli, R.4    Schols, D.5    De Clercq, E.6
  • 38
    • 77951758771 scopus 로고    scopus 로고
    • Endothelial progenitor cell transplantation improves long-term stroke outcome in mice
    • Fan Y, Shen F, Frenzel T, Zhu W, Ye J, Liu J et al. Endothelial progenitor cell transplantation improves long-term stroke outcome in mice. Ann Neurol 2010; 67: 488-497.
    • (2010) Ann Neurol , vol.67 , pp. 488-497
    • Fan, Y.1    Shen, F.2    Frenzel, T.3    Zhu, W.4    Ye, J.5    Liu, J.6
  • 39
    • 48549088793 scopus 로고    scopus 로고
    • The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus
    • Bhattacharyya BJ, Banisadr G, Jung H, Ren D, Cronshaw DG, Zou Y et al. The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus. J Neurosci 2008; 28: 6720-6730.
    • (2008) J Neurosci , vol.28 , pp. 6720-6730
    • Bhattacharyya, B.J.1    Banisadr, G.2    Jung, H.3    Ren, D.4    Cronshaw, D.G.5    Zou, Y.6
  • 40
    • 77954653333 scopus 로고    scopus 로고
    • CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination
    • Patel JR, McCandless EE, Dorsey D, Klein RS. CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination. Proc Natl Acad Sci USA 2010; 107: 11062-11067.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11062-11067
    • Patel, J.R.1    McCandless, E.E.2    Dorsey, D.3    Klein, R.S.4


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