IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Sun, Jie ^a   Zhang, Susu ^a   Zhang, Xiang ^a   Zhang, Xiaobao ^b   Dong, Hongquan ^a   Qian, Yanning ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b The First People's Hospital of Lianyungang City Department of Anesthesiology ^*  (China)

Author keywords

Cognitive impairment; IL 17A; Lipopolysaccharide; Microglia; Neuroinflammation

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 17; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; POSTSYNAPTIC DENSITY PROTEIN 95; TUMOR NECROSIS FACTOR ALPHA; ANTIBODY; CYTOKINE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CELL ACTIVATION; CELL CULTURE; COGNITIVE DEFECT; CONDITIONING; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; TRACE FEAR CONDITIONING; Y-MAZE TEST; AGING; ANIMAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOLOGY; INFLAMMATION; MAZE TEST; MEMORY DISORDERS; METABOLISM; NEWBORN; PATHOLOGY; SPRAGUE DAWLEY RAT; TIME FACTOR;

AGING; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; CELLS, CULTURED; CONDITIONING (PSYCHOLOGY); CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INFLAMMATION; INTERLEUKIN-17; LIPOPOLYSACCHARIDES; MALE; MAZE LEARNING; MEMORY DISORDERS; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84941652850     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0394-5     Document Type: Article

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