Aging enhances classical activation but mitigates alternative activation in the central nervous system

Neurobiology of Aging

Volumn 34, Issue 6, 2013, Pages 1610-1620

  Lee, Daniel C ^a,b   Ruiz, Claudia R ^d   Lebson, Lori ^d   Selenica, Maj Linda B ^a,b   Rizer, Justin ^b   Hunt, Jerry B ^a,b   Rojiani, Rahil ^a,b   Reid, Patrick ^a,b   Kammath, Sidharth ^b   Nash, Kevin ^b   Dickey, Chad A ^b,c   Gordon, Marcia ^b   Morgan, Dave ^b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative activation; Classical activation; Cytokines; Inflammation; Macrophage; Microarray; Microglia

Indexed keywords

ARGINASE 1; CALGRANULIN; CXCL13 CHEMOKINE; HAPTOGLOBIN; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; LIPOCALIN 1; RANTES; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE COURSE; DOWN REGULATION; HIPPOCAMPUS; MACROPHAGE; MICROARRAY ANALYSIS; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; UPREGULATION;

AGING; ANIMALS; CENTRAL NERVOUS SYSTEM; HIPPOCAMPUS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; SIGNAL TRANSDUCTION;

EID: 84875257460     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.12.014     Document Type: Article

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