Mefenamic acid taste-masked oral disintegrating tablets with enhanced solubility via molecular interaction produced by hot melt extrusion technology

Journal of Drug Delivery Science and Technology

Volumn 27, Issue , 2015, Pages 18-27

  Alshehri, Sultan M ^a   Park, Jun Bom ^b   Alsulays, Bader B ^a   Tiwari, Roshan V ^a   Almutairy, Bjad ^a   Alshetaili, Abdullah S ^a   Morott, Joseph ^a   Shah, Sejal ^a   Kulkarni, Vijay ^a   Majumdar, Soumyajit ^a   Martin, Scott T ^c   Mishra, Sanjay ^d   Wang, Lijia ^d   Repka, Michael A ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b Sahmyook University   (South Korea)

^c Thermo Fisher Scientific   (United States)

^d University of Memphis   (United States)

Author keywords

Hot melt extrusion; Molecular interaction; Orally disintegrating tablets; Solid dispersion; Solubility enhancement; Taste masking effect

Indexed keywords

AEROSIL; CROSPOVIDONE; EUDRAGIT; MAGNESIUM STEARATE; MEFENAMIC ACID; MICROCRYSTALLINE CELLULOSE;

ARTICLE; BITTER TASTE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG MANUFACTURE; DRUG SOLUBILITY; HOT MELT EXTRUSION PROCESS; HYDROGEN BOND; INFRARED SPECTROSCOPY; MASKING; MOLECULAR INTERACTION; ORALLY DISINTEGRATING TABLET; POWDER X RAY DIFFRACTION ANALYSIS; SCANNING ELECTRON MICROSCOPY; TABLET; TABLET DISINTEGRATION TIME; TABLET FRIABILITY; TASTE MASKING EFFECT; X RAY DIFFRACTION;

EID: 84941645173     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jddst.2015.03.003     Document Type: Article

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