Physical properties and in vivo bioavailability in human volunteers of isradipine using controlled release matrix tablet containing self-emulsifying solid dispersion

International Journal of Pharmaceutics

Volumn 450, Issue 1-2, 2013, Pages 79-86

  Tran, Phuong Ha Lien ^a   Tran, Thao Truong Dinh ^a   Piao, Zong Zhu ^b   Van Vo, Toi ^a   Park, Jun Bom ^b   Lim, Jisung ^c   Oh, Kyung Teak ^d   Rhee, Yun Seok ^e   Lee, Beom Jin ^b  

^a INTERNATIONAL UNIVERSITY   (Viet Nam)

^b Ajou University   (South Korea)

^c Kangwon National University   (South Korea)

^d Chung Ang University   (South Korea)

^e Gyeongsang National University   (South Korea)

Author keywords

Controlled release tablet; Enhanced dissolution; In vivo bioavailability; Physicochemical properties; Self emulsifying solid dispersion

Indexed keywords

ISRADIPINE;

ADULT; ARTICLE; CONTROLLED DRUG RELEASE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; HUMAN; IN VIVO STUDY; MATRIX TABLET; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PH; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TABLET FORMULATION; TEMPERATURE; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ADULT; ANTIHYPERTENSIVE AGENTS; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CALORIMETRY, DIFFERENTIAL SCANNING; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; HUMANS; ISRADIPINE; OLEIC ACID; POLYMERS; POWDER DIFFRACTION; SILICON DIOXIDE; SOLUBILITY; SURFACE-ACTIVE AGENTS; TABLETS; X-RAY DIFFRACTION; YOUNG ADULT;

EID: 84877625799     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.022     Document Type: Article

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