Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt extrusion technology

AAPS PharmSciTech

Volumn 13, Issue 4, 2012, Pages 1158-1169

  Mohammed, Noorullah Naqvi ^a   Majumdar, Soumyajit ^b   Singh, Abhilasha ^b   Deng, Weibin ^b   Murthy, Narasimha S ^b   Pinto, Elanor ^c   Tewari, Divya ^c   Durig, Thomas ^c   Repka, Michael A ^b  

^a Pharmaceutics International Inc   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c ASHLAND INC   (United States)

Author keywords

hot melt extrusion; Klucel EF ELF; solid solutions dispersions; solubility enhancement; thermal miscibility evaluation

Indexed keywords

AEROSIL; CROSCARMELLOSE SODIUM; EXCIPIENT; HYDROXYPROPYLCELLULOSE; KETOPROFEN; MAGNESIUM STEARATE; MANNITOL; MICROCRYSTALLINE CELLULOSE; POLYMER;

ARTICLE; DRUG FORMULATION; DRUG MANUFACTURE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOT MELT EXTRUSION; IN VITRO STUDY; PELLET EXTRUSION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPE; TABLET COMPRESSION; THERMOGRAVIMETRY; X RAY DIFFRACTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPSULES; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; DRUG IMPLANTS; DRUG STABILITY; EXCIPIENTS; HARDNESS TESTS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KETOPROFEN; MANNITOL; PARTICLE SIZE; POLYMERS; POROSITY; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84871648907     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-012-9834-z     Document Type: Article

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