-
1
-
-
84874010711
-
Tuberculosis
-
Zumla, A., Raviglione, M., Hafner, R. & von Reyn, C. F. Tuberculosis. N Engl J Med 368, 745-755, doi: 10.1056/NEJMra1200894 (2013).
-
(2013)
N Engl J Med
, vol.368
, pp. 745-755
-
-
Zumla, A.1
Raviglione, M.2
Hafner, R.3
Von Reyn, C.F.4
-
2
-
-
84937395323
-
-
CDC (U.S. Department of Health and Human Services Centers for Disease Control and Prevention, 2013)
-
CDC. Trends in Tuberculosis, 2013. (U.S. Department of Health and Human Services Centers for Disease Control and Prevention, 2013).
-
(2013)
Trends in Tuberculosis
-
-
-
3
-
-
84880126124
-
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
-
Mattila, J. T., et al. Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms. J Immunol 191, 773-784, doi: 10.4049/jimmunol.1300113 (2013).
-
(2013)
J Immunol
, vol.191
, pp. 773-784
-
-
Mattila, J.T.1
-
4
-
-
84856410386
-
Mycobacterium tuberculosis: Immune evasion, latency and reactivation
-
Gupta, A., Kaul, A., Tsolaki, A. G., Kishore, U. & Bhakta, S. Mycobacterium tuberculosis: immune evasion, latency and reactivation. Immunobiology 217, 363-374, doi: 10.1016/j.imbio.2011.07.008 (2012).
-
(2012)
Immunobiology
, vol.217
, pp. 363-374
-
-
Gupta, A.1
Kaul, A.2
Tsolaki, A.G.3
Kishore, U.4
Bhakta, S.5
-
5
-
-
79953279193
-
Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
-
Adams, K. N., et al. Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145, 39-53, doi: 10.1016/j.cell.2011.02.022 (2011).
-
(2011)
Cell
, vol.145
, pp. 39-53
-
-
Adams, K.N.1
-
6
-
-
84860247190
-
Revisiting the role of the granuloma in tuberculosis
-
Ramakrishnan, L. Revisiting the role of the granuloma in tuberculosis. Nat Rev Immunol 12, 352-366, doi: 10.1038/nri3211 (2012).
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 352-366
-
-
Ramakrishnan, L.1
-
7
-
-
84902208513
-
Multidrug-resistant and extensively drug-resistant tuberculosis: A review of current concepts and future challenges
-
Gunther, G. Multidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges. Clin Med 14, 279-285, doi: 10.7861/clinmedicine.14-3-279 (2014).
-
(2014)
Clin Med
, vol.14
, pp. 279-285
-
-
Gunther, G.1
-
9
-
-
84885395522
-
Serum drug concentrations predictive of pulmonary tuberculosis outcomes
-
Pasipanodya, J. G., et al. Serum drug concentrations predictive of pulmonary tuberculosis outcomes. J Infect Dis 208, 1464-1473, doi: 10.1093/infdis/jit352 (2013).
-
(2013)
J Infect Dis
, vol.208
, pp. 1464-1473
-
-
Pasipanodya, J.G.1
-
10
-
-
0031757665
-
Fitness of antibiotic-resistant microorganisms and compensatory mutations
-
Bottger, E. C., Springer, B., Pletschette, M. & Sander, P. Fitness of antibiotic-resistant microorganisms and compensatory mutations. Nat Med 4, 1343-1344, doi: 10.1038/3906 (1998).
-
(1998)
Nat Med
, vol.4
, pp. 1343-1344
-
-
Bottger, E.C.1
Springer, B.2
Pletschette, M.3
Sander, P.4
-
11
-
-
0036237703
-
Fitness cost of chromosomal drug resistance-conferring mutations
-
Sander, P., et al. Fitness cost of chromosomal drug resistance-conferring mutations. Antimicrob Agents Chemother 46, 1204-1211 (2002).
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 1204-1211
-
-
Sander, P.1
-
12
-
-
84908565694
-
In vivo efficacy of apramycin in murine infection models
-
Meyer, M., et al. In vivo efficacy of apramycin in murine infection models. Antimicrob Agents Chemother 58, 6938-6941, doi: 10.1128/AAC.03239-14 (2014).
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 6938-6941
-
-
Meyer, M.1
-
13
-
-
84863599921
-
Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin
-
Matt, T., et al. Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin. Proc Natl Acad Sci USA 109, 10984-10989, doi: 10.1073/pnas.1204073109 (2012).
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 10984-10989
-
-
Matt, T.1
-
14
-
-
0034702247
-
A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
-
Stover, C. K., et al. A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis. Nature 405, 962-966, doi: 10.1038/35016103 (2000).
-
(2000)
Nature
, vol.405
, pp. 962-966
-
-
Stover, C.K.1
-
15
-
-
33845323336
-
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice
-
Matsumoto, M., et al. OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. PLoS Med 3, e466, doi: 10.1371/journal.pmed.0030466 (2006).
-
(2006)
PLoS Med
, vol.3
, pp. e466
-
-
Matsumoto, M.1
-
16
-
-
84861140844
-
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: Long-term outcome, tolerability, and effect on emergence of drug resistance
-
Diacon, A. H., et al. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. Antimicrob Agents Chemother 56, 3271-3276, doi: 10.1128/AAC.06126-11 (2012).
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 3271-3276
-
-
Diacon, A.H.1
-
17
-
-
27744496465
-
Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines
-
Protopopova, M., et al. Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines. J Antimicrob Chemother 56, 968-974, doi: 10.1093/jac/dki319 (2005).
-
(2005)
J Antimicrob Chemother
, vol.56
, pp. 968-974
-
-
Protopopova, M.1
-
18
-
-
84920176601
-
In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis
-
Upton, A. M., et al. In vitro and in vivo activities of the nitroimidazole TBA-354 against Mycobacterium tuberculosis. Antimicrob Agents Chemother 59, 136-144, doi: 10.1128/AAC.03823-14 (2015).
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 136-144
-
-
Upton, A.M.1
-
19
-
-
80051572614
-
Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux
-
Louw, G. E., et al. Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux. Am J Respir Crit Care Med 184, 269-276, doi: 10.1164/rccm.201011-1924OC (2011).
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 269-276
-
-
Louw, G.E.1
-
20
-
-
84883514966
-
Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor
-
Gupta, S., et al. Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor. Am J Respir Crit Care Med 188, 600-607, doi: 10.1164/rccm.201304-0650OC (2013).
-
(2013)
Am J Respir Crit Care Med
, vol.188
, pp. 600-607
-
-
Gupta, S.1
-
21
-
-
84893661669
-
Spectinamides: A new class of semisynthetic antituberculosis agents that overcome native drug efflux
-
Lee, R. E., et al. Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux. Nat Med, doi: 10.1038/nm.3458 (2014).
-
(2014)
Nat Med
-
-
Lee, R.E.1
-
22
-
-
0034699519
-
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
-
Carter, A. P., et al. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 407, 340-348, doi: 10.1038/35030019 (2000).
-
(2000)
Nature
, vol.407
, pp. 340-348
-
-
Carter, A.P.1
-
23
-
-
84908429123
-
Identification and evaluation of improved 4? -O-(alkyl) 4,5-disubstituted 2-deoxystreptamines as next-generation aminoglycoside antibiotics
-
Duscha, S., et al. Identification and evaluation of improved 4? -O-(alkyl) 4,5-disubstituted 2-deoxystreptamines as next-generation aminoglycoside antibiotics. mBio 5, e01827-01814, doi: 10.1128/mBio.01827-14 (2014).
-
(2014)
MBio
, vol.5
, pp. e01827-01834
-
-
Duscha, S.1
-
24
-
-
58549117857
-
Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity
-
Hobbie, S. N., et al. Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity. Proc Natl Acad Sci USA 105, 20888-20893, doi: 10.1073/pnas.0811258106 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20888-20893
-
-
Hobbie, S.N.1
-
25
-
-
84893267937
-
4′-O-substitutions determine selectivity of aminoglycoside antibiotics
-
Perez-Fernandez, D., et al. 4′-O-substitutions determine selectivity of aminoglycoside antibiotics. Nat Commun 5, 3112, doi: 10.1038/ncomms4112 (2014).
-
(2014)
Nat Commun
, vol.5
, pp. 3112
-
-
Perez-Fernandez, D.1
-
26
-
-
84940756084
-
Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis during treatment of human tuberculosis
-
Walter, N. D., et al. Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis during treatment of human tuberculosis. J Infect Dis, doi: 10.1093/infdis/jiv149 (2015).
-
(2015)
J Infect Dis
-
-
Walter, N.D.1
-
27
-
-
84860199877
-
Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates
-
Balganesh, M., et al. Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates. Antimicrob Agents Chemother 56, 2643-2651, doi: 10.1128/AAC.06003-11 (2012).
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 2643-2651
-
-
Balganesh, M.1
-
28
-
-
79960302847
-
Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen
-
Ramon-Garcia, S., et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother 55, 3861-3869, doi: 10.1128/AAC.00474-11 (2011).
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 3861-3869
-
-
Ramon-Garcia, S.1
-
29
-
-
3042810717
-
Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA
-
Bauer, G., Berens, C., Projan, S. J. & Hillen, W. Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA. J Antimicrob Chemother 53, 592-599, doi: 10.1093/jac/dkh125 (2004).
-
(2004)
J Antimicrob Chemother
, vol.53
, pp. 592-599
-
-
Bauer, G.1
Berens, C.2
Projan, S.J.3
Hillen, W.4
-
30
-
-
0026497536
-
Pharmacokinetics of clarithromycin, a new macrolide, after single ascending oral doses
-
Chu, S. Y., et al. Pharmacokinetics of clarithromycin, a new macrolide, after single ascending oral doses. Antimicrob Agents Chemother 36, 2447-2453 (1992).
-
(1992)
Antimicrob Agents Chemother
, vol.36
, pp. 2447-2453
-
-
Chu, S.Y.1
-
31
-
-
0032801886
-
Bioavailability and selected pharmacokinetic parameters of clindamycin hydrochloride after administration of a new 600 mg tablet formulation
-
Mazur, D., et al. Bioavailability and selected pharmacokinetic parameters of clindamycin hydrochloride after administration of a new 600 mg tablet formulation. Int J Clin Pharmacol Ther 37, 386-392 (1999).
-
(1999)
Int J Clin Pharmacol Ther
, vol.37
, pp. 386-392
-
-
Mazur, D.1
-
32
-
-
0021369323
-
Bioavailability of doxycycline monohydrate. A comparison with equivalent doses of doxycycline hydrochloride
-
Malmborg, A. S. Bioavailability of doxycycline monohydrate. A comparison with equivalent doses of doxycycline hydrochloride. Chemotherapy 30, 76-80 (1984).
-
(1984)
Chemotherapy
, vol.30
, pp. 76-80
-
-
Malmborg, A.S.1
-
33
-
-
0021123268
-
Comparative bioavailability of tetracycline and lymecycline
-
Sjolin-Forsberg, G. & Hermansson, J. Comparative bioavailability of tetracycline and lymecycline. Br J Clin Pharmacol 18, 529-533 (1984).
-
(1984)
Br J Clin Pharmacol
, vol.18
, pp. 529-533
-
-
Sjolin-Forsberg, G.1
Hermansson, J.2
-
34
-
-
0028859487
-
Antituberculosis activity of clarithromycin
-
Luna-Herrera, J., Reddy, V. M., Daneluzzi, D. & Gangadharam, P. R. Antituberculosis activity of clarithromycin. Antimicrob Agents Chemother 39, 2692-2695 (1995).
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 2692-2695
-
-
Luna-Herrera, J.1
Reddy, V.M.2
Daneluzzi, D.3
Gangadharam, P.R.4
-
35
-
-
19544364888
-
Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models
-
Lenaerts, A. J., et al. Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models. Antimicrob Agents Chemother 49, 2294-2301, doi: 10.1128/AAC.49.6.2294-2301.2005 (2005).
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 2294-2301
-
-
Lenaerts, A.J.1
-
36
-
-
39049161926
-
Preclinical testing of new drugs for tuberculosis: Current challenges
-
Lenaerts, A. J., Degroote, M. A. & Orme, I. M. Preclinical testing of new drugs for tuberculosis: current challenges. Trends Microbiol 16, 48-54, doi: 10.1016/j.tim.2007.12.002 (2008).
-
(2008)
Trends Microbiol
, vol.16
, pp. 48-54
-
-
Lenaerts, A.J.1
Degroote, M.A.2
Orme, I.M.3
-
37
-
-
0037308582
-
Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against Streptococcus pneumoniae in a murine lung infection model
-
Hoffman, H. L., et al. Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against Streptococcus pneumoniae in a murine lung infection model. Antimicrob Agents Chemother 47, 739-746 (2003).
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 739-746
-
-
Hoffman, H.L.1
-
38
-
-
0035428052
-
Overcoming bacterial resistance by dual target inhibition: The case of streptogramins
-
Canu, A. & Leclercq, R. Overcoming bacterial resistance by dual target inhibition: the case of streptogramins. Curr Drug Target Infect Disord 1, 215-225 (2001).
-
(2001)
Curr Drug Target Infect Disord
, vol.1
, pp. 215-225
-
-
Canu, A.1
Leclercq, R.2
-
39
-
-
79952126850
-
The combination of rifampin plus moxifloxacin is synergistic for suppression of resistance but antagonistic for cell kill of Mycobacterium tuberculosis as determined in a hollow-fiber infection model
-
Drusano, G. L., et al. The combination of rifampin plus moxifloxacin is synergistic for suppression of resistance but antagonistic for cell kill of Mycobacterium tuberculosis as determined in a hollow-fiber infection model. mBio 1, doi: 10.1128/mBio.00139-10 (2010).
-
(2010)
MBio
, vol.1
-
-
Drusano, G.L.1
-
40
-
-
84901609343
-
Salvage therapy for multidrug-resistant tuberculosis
-
Seung, K. J., et al. Salvage therapy for multidrug-resistant tuberculosis. Clin Microbiol Infect 20, 441-446, doi: 10.1111/1469- 0691.12335 (2014).
-
(2014)
Clin Microbiol Infect
, vol.20
, pp. 441-446
-
-
Seung, K.J.1
-
41
-
-
84868004842
-
World Health Organization group 5 drugs for the treatment of drug-resistant tuberculosis: Unclear efficacy or untapped potential?
-
Dooley, K. E., et al. World Health Organization group 5 drugs for the treatment of drug-resistant tuberculosis: unclear efficacy or untapped potential? J Infect Dis 207, 1352-1358, doi: 10.1093/infdis/jis460 (2013).
-
(2013)
J Infect Dis
, vol.207
, pp. 1352-1358
-
-
Dooley, K.E.1
-
42
-
-
77955872446
-
Best drug treatment for multidrug-resistant and extensively drugresistant tuberculosis
-
Caminero, J. A., Sotgiu, G., Zumla, A. & Migliori, G. B. Best drug treatment for multidrug-resistant and extensively drugresistant tuberculosis. Lancet Infect Dis 10, 621-629, doi: 10.1016/S1473-3099(10)70139-0 (2010).
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 621-629
-
-
Caminero, J.A.1
Sotgiu, G.2
Zumla, A.3
Migliori, G.B.4
-
43
-
-
84890102278
-
Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients
-
Bolhuis, M. S., et al. Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients. Eur Respir J 42, 1614-1621, doi: 10.1183/09031936.00001913 (2013).
-
(2013)
Eur Respir J
, vol.42
, pp. 1614-1621
-
-
Bolhuis, M.S.1
-
44
-
-
16244366774
-
In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis
-
Falzari, K., et al. In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis. Antimicrob Agents Chemother 49, 1447-1454, doi: 10.1128/AAC.49.4.1447-1454.2005 (2005).
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1447-1454
-
-
Falzari, K.1
-
45
-
-
84881367368
-
A medicinal chemists guide to the unique difficulties of lead optimization for tuberculosis
-
Dartois, V. & Barry, C. E., 3rd. A medicinal chemists guide to the unique difficulties of lead optimization for tuberculosis. Bioorg Med Chem Lett 23, 4741-4750, doi: 10.1016/j.bmcl.2013.07.006 (2013).
-
(2013)
Bioorg Med Chem Lett
, vol.23
, pp. 4741-4750
-
-
Dartois, V.1
Barry, C.E.2
-
46
-
-
0037310195
-
Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice
-
Lenaerts, A. J., Gruppo, V., Brooks, J. V. & Orme, I. M. Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice. Antimicrob Agents Chemother 47, 783-785 (2003).
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 783-785
-
-
Lenaerts, A.J.1
Gruppo, V.2
Brooks, J.V.3
Orme, I.M.4
-
47
-
-
0027503118
-
Activity of erythromycin and clindamycin in an experimental Staphylococcus aureus infection in normal and granulocytopenic mice. A comparative in vivo and in vitro study
-
Hoogeterp, J. J., Mattie, H. & van Furth, R. Activity of erythromycin and clindamycin in an experimental Staphylococcus aureus infection in normal and granulocytopenic mice. A comparative in vivo and in vitro study. Scand J Infect Dis 25, 123-132 (1993).
-
(1993)
Scand J Infect Dis
, vol.25
, pp. 123-132
-
-
Hoogeterp, J.J.1
Mattie, H.2
Van Furth, R.3
-
48
-
-
0019482977
-
Antibiotic levels in infected and sterile subcutaneous abscesses in mice
-
Joiner, K. A., Lowe, B. R., Dzink, J. L. & Bartlett, J. G. Antibiotic levels in infected and sterile subcutaneous abscesses in mice. J Infect Dis 143, 487-494 (1981).
-
(1981)
J Infect Dis
, vol.143
, pp. 487-494
-
-
Joiner, K.A.1
Lowe, B.R.2
Dzink, J.L.3
Bartlett, J.G.4
-
49
-
-
0024416049
-
In vitro and in vivo activities of clarithromycin against Mycobacterium avium
-
Fernandes, P. B., Hardy, D. J., McDaniel, D., Hanson, C. W. & Swanson, R. N. In vitro and in vivo activities of clarithromycin against Mycobacterium avium. Antimicrob Agents Chemother 33, 1531-1534 (1989).
-
(1989)
Antimicrob Agents Chemother
, vol.33
, pp. 1531-1534
-
-
Fernandes, P.B.1
Hardy, D.J.2
McDaniel, D.3
Hanson, C.W.4
Swanson, R.N.5
-
50
-
-
0025968247
-
Individual and combined activities of clarithromycin and its 14-hydroxy metabolite in a murine model of Haemophilus influenzae infection
-
Vallee, E., Azoulay-Dupuis, E., Swanson, R., Bergogne-Berezin, E. & Pocidalo, J. J. Individual and combined activities of clarithromycin and its 14-hydroxy metabolite in a murine model of Haemophilus influenzae infection. J Antimicrob Chemother 27 Suppl A, 31-41 (1991).
-
(1991)
J Antimicrob Chemother
, vol.27
, pp. 31-41
-
-
Vallee, E.1
Azoulay-Dupuis, E.2
Swanson, R.3
Bergogne-Berezin, E.4
Pocidalo, J.J.5
-
51
-
-
3042577722
-
Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of Lyme borreliosis
-
Zeidner, N. S., et al. Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of Lyme borreliosis. Antimicrob Agents Chemother 48, 2697-2699, doi: 10.1128/AAC.48.7.2697-2699.2004 (2004).
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2697-2699
-
-
Zeidner, N.S.1
-
52
-
-
39149090668
-
Pharmacodynamics of doxycycline for chemoprophylaxis of Lyme disease: Preliminary findings and possible implications for other antimicrobials
-
Lee, J. & Wormser, G. P. Pharmacodynamics of doxycycline for chemoprophylaxis of Lyme disease: preliminary findings and possible implications for other antimicrobials. Int J Antimicrob Agents 31, 235-239, doi: 10.1016/j.ijantimicag.2007.11.011 (2008).
-
(2008)
Int J Antimicrob Agents
, vol.31
, pp. 235-239
-
-
Lee, J.1
Wormser, G.P.2
-
53
-
-
50949110277
-
Efficacy of quinoxaline-2-carboxylate 14-di-N-oxide derivatives in experimental tuberculosis
-
Vicente, E., et al. Efficacy of quinoxaline-2-carboxylate 1,4-di-N-oxide derivatives in experimental tuberculosis. Antimicrob Agents Chemother 52, 3321-3326, doi: 10.1128/AAC.00379-08 (2008).
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3321-3326
-
-
Vicente, E.1
-
54
-
-
39049161926
-
Preclinical testing of new drugs for tuberculosis: Current challenges
-
Lenaerts, A. J., Degroote, M. A. & Orme, I. M. Preclinical testing of new drugs for tuberculosis: current challenges. Trends Microbiol 16, 48-54, doi: 10.1016/j.tim.2007.12.002 (2008).
-
(2008)
Trends Microbiol
, vol.16
, pp. 48-54
-
-
Lenaerts, A.J.1
Degroote, M.A.2
Orme, I.M.3
-
55
-
-
79952336855
-
Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis
-
De Groote, M. A., et al. Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis. Antimicrobial Agents Chemother 55, 1237-1247, doi: 10.1128/AAC.00595-10 (2011).
-
(2011)
Antimicrobial Agents Chemother
, vol.55
, pp. 1237-1247
-
-
De Groote, M.A.1
-
56
-
-
84856077753
-
Importance of confirming data on the in vivo efficacy of novel antibacterial drug regimens against various strains of Mycobacterium tuberculosis
-
De Groote, M. A., et al. Importance of confirming data on the in vivo efficacy of novel antibacterial drug regimens against various strains of Mycobacterium tuberculosis. Antimicrobial Agents Chemother 56, 731-738, doi: 10.1128/AAC.05701-11 (2012).
-
(2012)
Antimicrobial Agents Chemother
, vol.56
, pp. 731-738
-
-
De Groote, M.A.1
-
57
-
-
84869214331
-
Structure-activity relationships among the kanamycin aminoglycosides: Role of ring i hydroxyl and amino groups
-
Salian, S., et al. Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxyl and amino groups. Antimicrob Agents Chemother 56, 6104-6108, doi: 10.1128/AAC.01326-12 (2012).
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 6104-6108
-
-
Salian, S.1
|