Sustained-release formulation of doxycycline hyclate for prophylaxis of tick bite infection in a murine model of lyme borreliosis

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 7, 2004, Pages 2697-2699

  Zeidner, N S ^a   Brandt, K S ^a   Dadey, E ^b   Dolan, M C ^a   Happ, C ^a   Piesman, J ^a  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^b QLT Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 2 PYRROLIDINONE; ATRIDOX; COPOLYMER; DOXYCYCLINE HYCLATE; POLYLACTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIUM CULTURE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FORMULATION; EXPERIMENTAL MODEL; FEMALE; HISTOPATHOLOGY; INFECTION PREVENTION; LYME DISEASE; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; SINGLE DRUG DOSE; SPIROCHETE; SUSTAINED RELEASE PREPARATION; TICK BITE;

ANIMALS; ANTI-BACTERIAL AGENTS; BITES AND STINGS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DOXYCYCLINE; FEMALE; INJECTIONS, SUBCUTANEOUS; LYME DISEASE; MICE; MICE, INBRED C3H; TICKS;

EID: 3042577722     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.7.2697-2699.2004     Document Type: Article

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