Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 5, 2012, Pages 2643-2651

  Balganesh, Meenakshi ^a   Dinesh, Neela ^a   Sharma, Sreevalli ^a   Kuruppath, Sanjana ^a,b   Nair, Anju V ^a,c   Sharma, Umender ^a  

^a ASTRAZENECA   (United Kingdom)

^b DEAKIN UNIVERSITY   (Australia)

^c INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMIKACIN; AZI 219; AZI 335; AZI 530; AZI 533; CLOFAZIMINE; ETHAMBUTOL; ETHIDIUM BROMIDE; GENTAMICIN; ISONIAZID; KANAMYCIN; PHENYLALANYLARGININE BETA NAPHTHYLAMIDE; RIFAMPICIN; RV 0849; RV 1218C; RV 1258C; RV 3065; SPECTINOMYCIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ANTIBIOTIC SENSITIVITY; ARTICLE; CONTROLLED STUDY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANTITUBERCULAR AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; CULTURE MEDIA; DIPEPTIDES; DRUG COMBINATIONS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; DRUG SYNERGISM; GENE KNOCKOUT TECHNIQUES; HOMOLOGOUS RECOMBINATION; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PLASMIDS; PYRAZOLONES; PYRROLES; TUBERCULOSIS, PULMONARY; VERAPAMIL;

EID: 84860199877     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.06003-11     Document Type: Article

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