High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling

Nature Communications

Volumn 6, Issue , 2015, Pages

  Zhao, Yuanbiao ^a   Londono, Pilar ^a   Cao, Yingqiong ^a   Sharpe, Emily J ^a   Proenza, Catherine ^a   O'Rourke, Rebecca ^a   Jones, Kenneth L ^a   Jeong, Mark Y ^a   Walker, Lori A ^a   Buttrick, Peter M ^a   McKinsey, Timothy A ^a   Song, Kunhua ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 1; MICRORNA 133; RHO KINASE; RHO KINASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; GATA4 PROTEIN, MOUSE; HAND2 PROTEIN, MOUSE; MEF2C PROTEIN, MOUSE; MIRN1 MICRORNA, MOUSE; MIRN133 MICRORNA, MOUSE; MYOCYTE ENHANCER FACTOR 2; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR 5; TRANSCRIPTION FACTOR GATA 4;

CARDIOVASCULAR SYSTEM; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GENE EXPRESSION; INHIBITION;

ADULT; ANIMAL CELL; ARTICLE; CELL KINETICS; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; FIBROBLAST; GENE EXPRESSION; HEART MUSCLE CELL; MOLECULAR DYNAMICS; MOLECULE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; SIGNAL TRANSDUCTION; ACTION POTENTIAL; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE CELL; CELL REPROGRAMMING TECHNIQUE; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; FIBROSIS; GENETICS; IMMUNOHISTOCHEMISTRY; MAMMALIAN EMBRYO; METABOLISM; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

ACTION POTENTIALS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CELLULAR REPROGRAMMING; CELLULAR REPROGRAMMING TECHNIQUES; CHROMATIN IMMUNOPRECIPITATION; EMBRYO, MAMMALIAN; FIBROBLASTS; FIBROSIS; GATA4 TRANSCRIPTION FACTOR; IMMUNOHISTOCHEMISTRY; MEF2 TRANSCRIPTION FACTORS; MICE; MICRORNAS; MYOCYTES, CARDIAC; REAL-TIME POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84941595669     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9243     Document Type: Article

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