The role of mTOR signaling in the regulation of protein synthesis and muscle mass during immobilization in mice

DMM Disease Models and Mechanisms

Volumn 8, Issue 9, 2015, Pages 1059-1069

  You, Jae Sung ^a,b   Anderson, Garrett B ^b   Dooley, Matthew S ^b   Hornberger, Troy A ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Atrophy; Contraction; Disuse; Rapamycin; Rheb; Skeletal muscle

Indexed keywords

INITIATION FACTOR 4F; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; MTOR PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; FIBER; HINDLIMB IMMOBILIZATION; IMMOBILIZATION; MOUSE; MUSCLE ATROPHY; MUSCLE ISOMETRIC CONTRACTION; MUSCLE MASS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUALITY OF LIFE; TRANSLATION REGULATION; UBIQUITINATION; ANIMAL; CHEMISTRY; IMMUNOHISTOCHEMISTRY; MECHANICAL STRESS; METABOLISM; MUSCLE CONTRACTION; PATHOLOGY; RIBOSOME; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

ANIMALS; EUKARYOTIC INITIATION FACTOR-4F; FEMALE; IMMOBILIZATION; IMMUNOHISTOCHEMISTRY; ISOMETRIC CONTRACTION; MICE; MUSCLE CONTRACTION; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PROTEIN BIOSYNTHESIS; RIBOSOMES; SIGNAL TRANSDUCTION; SIROLIMUS; STRESS, MECHANICAL; TOR SERINE-THREONINE KINASES;

EID: 84941568405     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.019414     Document Type: Article

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