Mechanical Stimulation Induces mTOR Signaling via an ERK-Independent Mechanism: Implications for a Direct Activation of mTOR by Phosphatidic Acid

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  You, Jae Sung ^a,b   Frey, John W ^b   Hornberger, Troy A ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDIC ACID; PROTEIN P70; RAPAMYCIN; SERINE; THREONINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; MECHANICAL STIMULATION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; TRANSGENIC MOUSE;

ANIMALS; CARRIER PROTEINS; MALE; MAP KINASE SIGNALING SYSTEM; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; ORGAN CULTURE TECHNIQUES; PHOSPHATIDIC ACIDS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN KINASE INHIBITORS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84867525052     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047258     Document Type: Article

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