Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice

Journal of Investigative Dermatology

Volumn 135, Issue 10, 2015, Pages 2484-2491

  Patricio, Eliziane S ^a   Costa, Robson ^a,b   Figueiredo, Claudia P ^a,b   Gers Barlag, Katharina ^c   Bicca, Maíra A ^a   Manjavachi, Marianne N ^a   Segat, Gabriela C ^a   Gentry, Clive ^c   Luiz, Ana P ^a   Fernandes, Elizabeth S ^c,d   Cunha, Thiago M ^e   Bevan, Stuart ^c   Calixto, João B ^a,f  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d CEUMA UNIVERSITY   (Brazil)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

^f Centro de Inova ão e Ensaios Pré Clínicos CIEnP   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; AYPGKF NH2 PEPTIDE; CAPSAICIN; CROMOGLYCATE DISODIUM; GASTRIN RELEASING PEPTIDE; N (4 ISOPROPYLPHENYL) 2 (1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXO 7H PURIN 7 YL)ACETAMIDE; N BENZYL N2 [4 HYDROXY 1 [(1 METHYL 1H INDOL 3 YL)CARBONYL]PROLYL] N METHYL 3 (2 NAPHTHYL)ALANINAMIDE; NALOXONE; PEPDUCIN P4PAL 10; PEPTIDE; PEPTIDE HORMONE ANTAGONIST; PROTEINASE ACTIVATED RECEPTOR 4; RC 3095; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; BOMBESIN RECEPTOR; PROTEASE-ACTIVATED RECEPTOR 4; THROMBIN RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRURICEPTIVE FIBER; PRURITUS; SCRATCHING; SENSORY NERVE; SENSORY NERVE CELL; SPINAL GANGLION; WILD TYPE; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; INTRADERMAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PSYCHOLOGY; RANDOMIZATION; REFERENCE VALUE; SIGNAL TRANSDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; CAPSAICIN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRADERMAL; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PRURITUS; RANDOM ALLOCATION; RECEPTORS, BOMBESIN; RECEPTORS, THROMBIN; REFERENCE VALUES; SIGNAL TRANSDUCTION; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84941415719     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.183     Document Type: Article

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