Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study

Pflugers Archiv European Journal of Physiology

Volumn 467, Issue 10, 2015, Pages 2093-2105

  Veeraraghavan, Rengasayee ^a   Lin, Joyce ^c   Hoeker, Gregory S ^a   Keener, James P ^d   Gourdie, Robert G ^a,b   Poelzing, Steven ^a,b  

^a VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^c CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

^d UNIVERSITY OF UTAH   (United States)

Author keywords

Arrhythmia; Cardiac conduction; Ephaptic coupling; Gap junctions; Sodium channels

Indexed keywords

FLECAINIDE; SODIUM CHANNEL NAV1.5; CONNEXIN 43;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANISOTROPY; ARTICLE; CELL INTERACTION; CELL MEMBRANE; ELECTRIC CONDUCTANCE; ELECTRICAL SYNAPSE; ELECTRON MICROSCOPY; EPHAPSE; EXCITATION CONTRACTION COUPLING; GAP JUNCTION; GUINEA PIG; HEART ARRHYTHMIA; HEART CONDUCTION; HEART EXCITATION; LUNG EDEMA; MALE; NONHUMAN; PRIORITY JOURNAL; ACTION POTENTIAL; ANIMAL; BIOLOGICAL MODEL; CARDIAC MUSCLE; EDEMA; METABOLISM; PATHOLOGY; ULTRASTRUCTURE;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; CONNEXIN 43; EDEMA; GAP JUNCTIONS; GUINEA PIGS; MALE; MODELS, NEUROLOGICAL; MYOCARDIUM; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL;

EID: 84941341276     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-014-1675-z     Document Type: Article

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