Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes

Heart Rhythm

Volumn 8, Issue 12, 2011, Pages 1923-1930

  Lin, Xianming ^a   Liu, Nian ^a   Lu, Jia ^a   Zhang, Jie ^a   Anumonwo, Justus M B ^b   Isom, Lori L ^b   Fishman, Glenn I ^a   Delmar, Mario ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Intercalated disc; Nav1.5; Sodium current

Indexed keywords

SODIUM CHANNEL; TETRODOTOXIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL HETEROGENEITY; ELECTRODE; HEART MUSCLE CELL; HEART VENTRICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PURKINJE CELL; RAT; SODIUM CURRENT; UPREGULATION;

ANIMALS; CELL COMMUNICATION; MICE; MYOCYTES, CARDIAC; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 82455175177     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2011.07.016     Document Type: Article

References (27)

1. S.A. Cohen Immunocytochemical localization of rH1 sodium channel in adult rat heart atria and ventricle: presence in terminal intercalated disks Circulation 94 1996 3083 3086
2. S.K. Maier, R.E. Westenbroek, K.A. McCormick, R. Curtis, T. Scheuer, and W.A. Catterall Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart Circulation 109 2004 1421 1427
3. J.P. Kucera, S. Rohr, and Y. Rudy Localization of sodium channels in intercalated disks modulates cardiac conduction Circ Res 91 2002 1176 1182
4. v1.5 in cardiomyocytes Circ Res 108 2011 294 304
5. J.D. Malhotra, V. Thyagarajan, C. Chen, and L.L. Isom Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes J Biol Chem 279 2004 40748 40754
6. J.S. Lowe, O. Palygin, and N. Bhasin Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway J Cell Biol 180 2008 173 186
7. P.Y. Sato, H. Musa, and W. Coombs Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes Circ Res 105 2009 523 526
8. P.Y. Sato, W. Coombs, and X. Lin Interactions between ankyrin-G, plakophilin-2, and connexin43 at the cardiac intercalated disc Circ Res 109 2011 193 201
9. + channel subunits in development and disease Neurosci Lett 486 2010 53 59
10. J. Dhar Malhotra, C. Chen, and I. Rivolta Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes Circulation 103 2001 1303 1310
11. + channels in rabbit ventricular myocytes Europace 9 2007 571 577
12. + channels in rabbit ventricular myocytes Europace 10 2008 257 author's response: 2008;10:257258
13. B.A. Pallante, S. Giovannone, and F.Y. Liu Contactin-2 expression in the cardiac Purkinje fiber network Circ Arrhythm Electrophysiol 3 2010 186 194
14. A.L. Goldin Resurgence of sodium channel research Annu Rev Physiol 63 2001 871 894
15. S.K. Maier, R.E. Westenbroek, K.A. Schenkman, E.O. Feigl, T. Scheuer, and W.A. Catterall An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart Proc Natl Acad Sci U S A 99 2002 4073 4078
16. F. Brette, and C.H. Orchard No apparent requirement for neuronal sodium channels in excitation-contraction coupling in rat ventricular myocytes Circ Res 98 2006 667 674
17. S.C. Benn, M. Costigan, S. Tate, M. Fitzgerald, and C.J. Woolf Developmental expression of the TTX-resistant voltage-gated sodium channels Nav1.8 (SNS) and Nav1.9 (SNS2) in primary sensory neurons J Neurosci 21 2001 6077 6085
18. G.E. Kirsch, and A.M. Brown Kinetics properties of single sodium channels in rat heart and rat brain J Gen Physiol 93 1989 85 99
19. S.A. Grandy, J. Brouillette, and C. Fiset Reduction of ventricular sodium current in a mouse model of HIV J Cardiovasc Electrophysiol 21 2010 916 922
20. N. Sotoodehnia, A. Isaacs, and P.I. de Bakker Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction Nat Genet 42 2010 1068 1076
21. + channel distributions in the mechanism of cardiac conduction Biophys J 100 2011 554 563
22. Y. Mori, G.I. Fishman, and C.S. Peskin Ephaptic conduction in a cardiac strand model with 3D electrodiffusion Proc Natl Acad Sci U S A 105 2008 6463 6468
23. O.V. Aslanidi, R.N. Sleiman, M.R. Boyett, J.C. Hancox, and H. Zhang Ionic mechanisms for electrical heterogeneity between rabbit Purkinje fiber and ventricular cells Biophys J 98 2010 2420 2431
24. X.H. He, Y. Zang, and X. Chen TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury Pain 151 2010 266 279
25. X. Chen, R.P. Pang, and K.F. Shen TNF-α enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury Exp Neurol 227 2011 279 286
26. X. Jin, and I.V. Gereau Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-α J Neurosci 26 2006 246 255
27. H. Abriel Cardiac sodium channel Nav1.5 and interacting proteins: physiology and pathophysiology J Mol Cell Cardiol 48 2010 2 11