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Volumn 29, Issue 8, 2015, Pages 2022-2029

Ammonia impairs glutamatergic communication in astroglial cells: Protective role of resveratrol

Author keywords

Ammonia; C6 Astroglial cells; Glutamate; Resveratrol

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMMONIA; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMIC ACID; GLUTATHIONE; HEME OXYGENASE 1; RESVERATROL; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; GLUTAMATE AMMONIA LIGASE; SLC1A1 PROTEIN, RAT; STILBENE DERIVATIVE;

EID: 84941285095     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2015.08.008     Document Type: Article
Times cited : (22)

References (88)
  • 1
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Abraham N.G., Kappas A. Pharmacological and clinical aspects of heme oxygenase. Pharmacol. Rev. 2008, 60:79-127. 10.1124/pr.107.07104.
    • (2008) Pharmacol. Rev. , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 2
    • 0033619660 scopus 로고    scopus 로고
    • Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome
    • Albrecht J., Jones E.A. Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome. J. Neurol. Sci. 1999, 170:138-146.
    • (1999) J. Neurol. Sci. , vol.170 , pp. 138-146
    • Albrecht, J.1    Jones, E.A.2
  • 3
    • 0033779559 scopus 로고    scopus 로고
    • Astrocyte glutamate transport: review of properties, regulation, and physiological functions
    • Anderson C.M., Swanson R.A. Astrocyte glutamate transport: review of properties, regulation, and physiological functions. Glia 2000, 32:1-14.
    • (2000) Glia , vol.32 , pp. 1-14
    • Anderson, C.M.1    Swanson, R.A.2
  • 4
    • 50449107176 scopus 로고    scopus 로고
    • The undertow of sulfur metabolism on glutamatergic neurotransmission
    • Banerjee R., Vitvitsky V., Garg S.K. The undertow of sulfur metabolism on glutamatergic neurotransmission. Trends Biochem. Sci. 2008, 33:413-419. 10.1016/j.tibs.2008.06.006.
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 413-419
    • Banerjee, R.1    Vitvitsky, V.2    Garg, S.K.3
  • 5
    • 77956444535 scopus 로고    scopus 로고
    • Heme oxygenase 1: another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule
    • Bastianetto S., Quirion R. Heme oxygenase 1: another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule. Exp. Neurol. 2010, 225:237-239. 10.1016/j.expneurol.2010.06.019.
    • (2010) Exp. Neurol. , vol.225 , pp. 237-239
    • Bastianetto, S.1    Quirion, R.2
  • 7
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • Baur J.A., Sinclair D.A. Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. Drug Discov. 2006, 5:493-506. 10.1038/nrd2060.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 8
    • 82955168362 scopus 로고    scopus 로고
    • Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation
    • Bélanger M., Allaman I., Magistretti P.J. Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab. 2011, 14:724-738. 10.1016/j.cmet.2011.08.016.
    • (2011) Cell Metab. , vol.14 , pp. 724-738
    • Bélanger, M.1    Allaman, I.2    Magistretti, P.J.3
  • 11
    • 84888219865 scopus 로고    scopus 로고
    • Elsevier/Academic Press, Amsterdam; Boston, S.T. Brady, G.J. Siegel, R.W. Albers, D.L. Price, J. Benjamins (Eds.)
    • Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology 2012, Elsevier/Academic Press, Amsterdam; Boston. 8th ed. S.T. Brady, G.J. Siegel, R.W. Albers, D.L. Price, J. Benjamins (Eds.).
    • (2012) Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology
  • 12
    • 0032253227 scopus 로고    scopus 로고
    • Reduced glutathione and glutathione disulfide
    • Browne R.W., Armstrong D. Reduced glutathione and glutathione disulfide. Methods Mol. Biol. Clifton NJ 1998, 108:347-352. 10.1385/0-89603-472-0:347.
    • (1998) Methods Mol. Biol. Clifton NJ , vol.108 , pp. 347-352
    • Browne, R.W.1    Armstrong, D.2
  • 13
    • 84908505093 scopus 로고    scopus 로고
    • Pathophysiology of brain dysfunction in hyperammonemic syndromes: the many faces of glutamine
    • Butterworth R.F. Pathophysiology of brain dysfunction in hyperammonemic syndromes: the many faces of glutamine. Mol. Genet. Metab. 2014, 113:113-117. 10.1016/j.ymgme.2014.06.003.
    • (2014) Mol. Genet. Metab. , vol.113 , pp. 113-117
    • Butterworth, R.F.1
  • 14
    • 84908505093 scopus 로고    scopus 로고
    • Pathophysiology of brain dysfunction in hyperammonemic syndromes: the many faces of glutamine
    • Butterworth R.F. Pathophysiology of brain dysfunction in hyperammonemic syndromes: the many faces of glutamine. Mol. Genet. Metab. 2014, 113:113-117. 10.1016/j.ymgme.2014.06.003.
    • (2014) Mol. Genet. Metab. , vol.113 , pp. 113-117
    • Butterworth, R.F.1
  • 15
    • 84884882968 scopus 로고    scopus 로고
    • The slowed brain: cortical oscillatory activity in hepatic encephalopathy
    • Butz M., May E.S., Häussinger D., Schnitzler A. The slowed brain: cortical oscillatory activity in hepatic encephalopathy. Arch. Biochem. Biophys. 2013, 536:197-203. 10.1016/j.abb.2013.04.004.
    • (2013) Arch. Biochem. Biophys. , vol.536 , pp. 197-203
    • Butz, M.1    May, E.S.2    Häussinger, D.3    Schnitzler, A.4
  • 17
    • 0022549284 scopus 로고
    • A direct colorimetric assay for Ca2+-stimulated ATPase activity
    • Chan K.M., Delfert D., Junger K.D. A direct colorimetric assay for Ca2+-stimulated ATPase activity. Anal. Biochem. 1986, 157:375-380.
    • (1986) Anal. Biochem. , vol.157 , pp. 375-380
    • Chan, K.M.1    Delfert, D.2    Junger, K.D.3
  • 18
    • 84879074528 scopus 로고    scopus 로고
    • Functional consequences of age-dependent changes in glutathione status in the brain
    • Currais A., Maher P. Functional consequences of age-dependent changes in glutathione status in the brain. Antioxid. Redox Signal. 2013, 19:813-822. 10.1089/ars.2012.4996.
    • (2013) Antioxid. Redox Signal. , vol.19 , pp. 813-822
    • Currais, A.1    Maher, P.2
  • 19
    • 84885441346 scopus 로고    scopus 로고
    • Ammonia-induced Na, K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling
    • Dai H., Song D., Xu J., Li B., Hertz L., Peng L. Ammonia-induced Na, K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling. Neurochem. Int. 2013, 63:610-625. 10.1016/j.neuint.2013.09.005.
    • (2013) Neurochem. Int. , vol.63 , pp. 610-625
    • Dai, H.1    Song, D.2    Xu, J.3    Li, B.4    Hertz, L.5    Peng, L.6
  • 20
  • 24
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain
    • Dringen R. Metabolism and functions of glutathione in brain. Prog. Neurobiol. 2000, 62:649-671.
    • (2000) Prog. Neurobiol. , vol.62 , pp. 649-671
    • Dringen, R.1
  • 26
    • 84888136598 scopus 로고    scopus 로고
    • Hepatic encephalopathy: effects of liver failure on brain function
    • Felipo V. Hepatic encephalopathy: effects of liver failure on brain function. Nat. Rev. Neurosci. 2013, 14:851-858. 10.1038/nrn3587.
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 851-858
    • Felipo, V.1
  • 27
    • 0036629585 scopus 로고    scopus 로고
    • Neurobiology of ammonia
    • Felipo V., Butterworth R.F. Neurobiology of ammonia. Prog. Neurobiol. 2002, 67:259-279. 10.1016/S0301-0082(02)00019-9.
    • (2002) Prog. Neurobiol. , vol.67 , pp. 259-279
    • Felipo, V.1    Butterworth, R.F.2
  • 29
    • 77950898706 scopus 로고    scopus 로고
    • Ammonia triggers exocytotic release of l-glutamate from cultured rat astrocytes
    • Görg B., Morwinsky A., Keitel V., Qvartskhava N., Schrör K., Häussinger D. Ammonia triggers exocytotic release of l-glutamate from cultured rat astrocytes. Glia 2010, 58:691-705. 10.1002/glia.20955.
    • (2010) Glia , vol.58 , pp. 691-705
    • Görg, B.1    Morwinsky, A.2    Keitel, V.3    Qvartskhava, N.4    Schrör, K.5    Häussinger, D.6
  • 30
    • 84884800246 scopus 로고    scopus 로고
    • Osmotic and oxidative/nitrosative stress in ammonia toxicity and hepatic encephalopathy
    • Görg B., Schliess F., Häussinger D. Osmotic and oxidative/nitrosative stress in ammonia toxicity and hepatic encephalopathy. Arch. Biochem. Biophys. 2013, 536:158-163. 10.1016/j.abb.2013.03.010.
    • (2013) Arch. Biochem. Biophys. , vol.536 , pp. 158-163
    • Görg, B.1    Schliess, F.2    Häussinger, D.3
  • 31
    • 84911986146 scopus 로고    scopus 로고
    • Ammonia-induced senescence in cultured rat astrocytes and in human cerebral cortex in hepatic encephalopathy
    • Görg B., Karababa A., Shafigullina A., Bidmon H.J., Häussinger D. Ammonia-induced senescence in cultured rat astrocytes and in human cerebral cortex in hepatic encephalopathy. Glia 2014, 10.1002/glia.22731.
    • (2014) Glia
    • Görg, B.1    Karababa, A.2    Shafigullina, A.3    Bidmon, H.J.4    Häussinger, D.5
  • 32
    • 0026730558 scopus 로고
    • Contribution of Na+, K(+)-ATPase to focal epilepsy: a brief review
    • Grisar T., Guillaume D., Delgado-Escueta A.V. Contribution of Na+, K(+)-ATPase to focal epilepsy: a brief review. Epilepsy Res. 1992, 12:141-149.
    • (1992) Epilepsy Res. , vol.12 , pp. 141-149
    • Grisar, T.1    Guillaume, D.2    Delgado-Escueta, A.V.3
  • 34
    • 84857501489 scopus 로고    scopus 로고
    • Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders
    • Haines D.D., Lekli I., Teissier P., Bak I., Tosaki A. Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders. Acta Physiol (Oxf.) 2012, 204:487-501. 10.1111/j.1748-1716.2011.02387.x.
    • (2012) Acta Physiol (Oxf.) , vol.204 , pp. 487-501
    • Haines, D.D.1    Lekli, I.2    Teissier, P.3    Bak, I.4    Tosaki, A.5
  • 36
    • 84939876839 scopus 로고    scopus 로고
    • Ammonia, Like K(+), stimulates the Na(+), K(+), 2 Cl(-) cotransporter NKCC1 and the Na(+), K(+)-ATPase and interacts with endogenous ouabain in astrocytes
    • Hertz L., Peng L., Song D. Ammonia, Like K(+), stimulates the Na(+), K(+), 2 Cl(-) cotransporter NKCC1 and the Na(+), K(+)-ATPase and interacts with endogenous ouabain in astrocytes. Neurochem. Res. 2014, 10.1007/s11064-014-1352-9.
    • (2014) Neurochem. Res.
    • Hertz, L.1    Peng, L.2    Song, D.3
  • 37
    • 77954142513 scopus 로고    scopus 로고
    • The Na-K-Cl Co-transporter in astrocyte swelling
    • Jayakumar A.R., Norenberg M.D. The Na-K-Cl Co-transporter in astrocyte swelling. Metab. Brain Dis. 2010, 25:31-38. 10.1007/s11011-010-9180-3.
    • (2010) Metab. Brain Dis. , vol.25 , pp. 31-38
    • Jayakumar, A.R.1    Norenberg, M.D.2
  • 40
    • 0002762662 scopus 로고
    • Amino acids and small peptides
    • IRL Press, Oxford, C.K. Lim (Ed.)
    • Joseph M.H., Marsden C.A. Amino acids and small peptides. HPLC of Small Peptides 1986, 13-27. IRL Press, Oxford. C.K. Lim (Ed.).
    • (1986) HPLC of Small Peptides , pp. 13-27
    • Joseph, M.H.1    Marsden, C.A.2
  • 41
    • 0033967123 scopus 로고    scopus 로고
    • +-ATPase activity, increase in potassium uptake, and enhanced production of ouabain-like compounds in ammonia-treated mouse astrocytes
    • +-ATPase activity, increase in potassium uptake, and enhanced production of ouabain-like compounds in ammonia-treated mouse astrocytes. Neurochem. Int. 2000, 36:203-211.
    • (2000) Neurochem. Int. , vol.36 , pp. 203-211
    • Kala, G.1    Kumarathasan, R.2    Peng, L.3    Leenen, F.H.4    Hertz, L.5
  • 42
    • 78149271756 scopus 로고    scopus 로고
    • Ammonium influx pathways into astrocytes and neurones of hippocampal slices
    • Kelly T., Rose C.R. Ammonium influx pathways into astrocytes and neurones of hippocampal slices. J. Neurochem. 2010, 115:1123-1136. 10.1111/j.1471-4159.2010.07009.x.
    • (2010) J. Neurochem. , vol.115 , pp. 1123-1136
    • Kelly, T.1    Rose, C.R.2
  • 43
    • 67650741991 scopus 로고    scopus 로고
    • Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity
    • Kelly T., Kafitz K.W., Roderigo C., Rose C.R. Ammonium-evoked alterations in intracellular sodium and pH reduce glial glutamate transport activity. Glia 2009, 57:921-934. 10.1002/glia.20817.
    • (2009) Glia , vol.57 , pp. 921-934
    • Kelly, T.1    Kafitz, K.W.2    Roderigo, C.3    Rose, C.R.4
  • 44
    • 0027988722 scopus 로고
    • Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and Na+, K(+)-ATPase
    • Kosenko E., Kaminsky Y., Grau E., Miñana M.D., Marcaida G., Grisolía S., Felipo V. Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and Na+, K(+)-ATPase. J. Neurochem. 1994, 63:2172-2178.
    • (1994) J. Neurochem. , vol.63 , pp. 2172-2178
    • Kosenko, E.1    Kaminsky, Y.2    Grau, E.3    Miñana, M.D.4    Marcaida, G.5    Grisolía, S.6    Felipo, V.7
  • 46
    • 84887937515 scopus 로고    scopus 로고
    • Neuroprotection by resveratrol in diabetic neuropathy: concepts & mechanisms
    • Kumar A., Negi G., Sharma S.S. Neuroprotection by resveratrol in diabetic neuropathy: concepts & mechanisms. Curr. Med. Chem. 2013, 20:4640-4645.
    • (2013) Curr. Med. Chem. , vol.20 , pp. 4640-4645
    • Kumar, A.1    Negi, G.2    Sharma, S.S.3
  • 47
    • 77954452230 scopus 로고    scopus 로고
    • Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases
    • Lee M., Cho T., Jantaratnotai N., Wang Y.T., McGeer E., McGeer P.L. Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases. FASEB 2010, 24:2533-2545. 10.1096/fj.09-149997.
    • (2010) FASEB , vol.24 , pp. 2533-2545
    • Lee, M.1    Cho, T.2    Jantaratnotai, N.3    Wang, Y.T.4    McGeer, E.5    McGeer, P.L.6
  • 50
    • 35348981179 scopus 로고    scopus 로고
    • Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling
    • Li M.-H., Jang J.-H., Na H.-K., Cha Y.-N., Surh Y.-J. Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. J. Biol. Chem. 2007, 282:28577-28586. 10.1074/jbc.M701916200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 28577-28586
    • Li, M.-H.1    Jang, J.-H.2    Na, H.-K.3    Cha, Y.-N.4    Surh, Y.-J.5
  • 51
    • 0026636168 scopus 로고
    • Na, K-ATPase: isoform structure, function, and expression
    • Lingrel J.B. Na, K-ATPase: isoform structure, function, and expression. J. Bioenerg. Biomembr. 1992, 24:263-270.
    • (1992) J. Bioenerg. Biomembr. , vol.24 , pp. 263-270
    • Lingrel, J.B.1
  • 53
    • 36849085955 scopus 로고    scopus 로고
    • Mechanisms of glutamate release from astrocytes
    • Malarkey E.B., Parpura V. Mechanisms of glutamate release from astrocytes. Neurochem. Int. 2008, 52:142-154. 10.1016/j.neuint.2007.06.005.
    • (2008) Neurochem. Int. , vol.52 , pp. 142-154
    • Malarkey, E.B.1    Parpura, V.2
  • 55
    • 35848947733 scopus 로고    scopus 로고
    • The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain
    • McKenna M.C. The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain. J. Neurosci. Res. 2007, 85:3347-3358. 10.1002/jnr.21444.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3347-3358
    • McKenna, M.C.1
  • 56
    • 0036093307 scopus 로고    scopus 로고
    • Molecular mechanism of acute ammonia toxicity: role of NMDA receptors
    • Monfort P., Kosenko E., Erceg S., Canales J.-J., Felipo V. Molecular mechanism of acute ammonia toxicity: role of NMDA receptors. Neurochem. Int. 2002, 41:95-102. 10.1016/S0197-0186(02)00029-3.
    • (2002) Neurochem. Int. , vol.41 , pp. 95-102
    • Monfort, P.1    Kosenko, E.2    Erceg, S.3    Canales, J.-J.4    Felipo, V.5
  • 57
    • 84911480727 scopus 로고    scopus 로고
    • Pathological role for exocytotic glutamate release from astrocytes in hepatic encephalopathy
    • Montana V., Verkhratsky A., Parpura V. Pathological role for exocytotic glutamate release from astrocytes in hepatic encephalopathy. Curr. Neuropharmacol. 2014, 12:324-333. 10.2174/1570159X12666140903094700.
    • (2014) Curr. Neuropharmacol. , vol.12 , pp. 324-333
    • Montana, V.1    Verkhratsky, A.2    Parpura, V.3
  • 58
    • 60449101891 scopus 로고    scopus 로고
    • Signaling factors in the mechanism of ammonia neurotoxicity
    • Norenberg M.D., Rama Rao K.V., Jayakumar A.R. Signaling factors in the mechanism of ammonia neurotoxicity. Metab. Brain Dis. 2009, 24:103-117. 10.1007/s11011-008-9113-6.
    • (2009) Metab. Brain Dis. , vol.24 , pp. 103-117
    • Norenberg, M.D.1    Rama Rao, K.V.2    Jayakumar, A.R.3
  • 59
    • 67650985925 scopus 로고    scopus 로고
    • Prolonged exposure to ammonia increases extracellular glutamate in cultured rat astrocytes
    • Ohara K., Aoyama M., Fujita M., Sobue K., Asai K. Prolonged exposure to ammonia increases extracellular glutamate in cultured rat astrocytes. Neurosci. Lett. 2009, 462:109-112. 10.1016/j.neulet.2009.06.090.
    • (2009) Neurosci. Lett. , vol.462 , pp. 109-112
    • Ohara, K.1    Aoyama, M.2    Fujita, M.3    Sobue, K.4    Asai, K.5
  • 60
    • 84938104525 scopus 로고    scopus 로고
    • The pharmacology of resveratrol in animals and humans
    • Park E.-J., Pezzuto J.M. The pharmacology of resveratrol in animals and humans. Biochim. Biophys. Acta 2015, 10.1016/j.bbadis.2015.01.014.
    • (2015) Biochim. Biophys. Acta
    • Park, E.-J.1    Pezzuto, J.M.2
  • 61
    • 84872776311 scopus 로고    scopus 로고
    • Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling
    • Parpura V., Verkhratsky A. Astrocytes revisited: concise historic outlook on glutamate homeostasis and signaling. Croat. Med. J. 2012, 53:518-528. 10.3325/cmj.2012.53.518.
    • (2012) Croat. Med. J. , vol.53 , pp. 518-528
    • Parpura, V.1    Verkhratsky, A.2
  • 62
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: from grapevines to mammalian biology
    • Pervaiz S. Resveratrol: from grapevines to mammalian biology. FASEB J. 2003, 17:1975-1985. 10.1096/fj.03-0168rev.
    • (2003) FASEB J. , vol.17 , pp. 1975-1985
    • Pervaiz, S.1
  • 63
    • 2342447943 scopus 로고    scopus 로고
    • Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury
    • Quan S., Yang L., Shnouda S., Schwartzman M.L., Nasjletti A., Goodman A.I., Abraham N.G. Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury. Kidney Int. 2004, 65:1628-1639. 10.1111/j.1523-1755.2004.00562.x.
    • (2004) Kidney Int. , vol.65 , pp. 1628-1639
    • Quan, S.1    Yang, L.2    Shnouda, S.3    Schwartzman, M.L.4    Nasjletti, A.5    Goodman, A.I.6    Abraham, N.G.7
  • 64
    • 78851472360 scopus 로고    scopus 로고
    • Resveratrol modulates astroglial functions: neuroprotective hypothesis
    • Quincozes-Santos A., Gottfried C. Resveratrol modulates astroglial functions: neuroprotective hypothesis. Ann. N. Y. Acad. Sci. 2011, 1215:72-78. 10.1111/j.1749-6632.2010.05857.x.
    • (2011) Ann. N. Y. Acad. Sci. , vol.1215 , pp. 72-78
    • Quincozes-Santos, A.1    Gottfried, C.2
  • 65
    • 84877770709 scopus 로고    scopus 로고
    • Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1
    • Quincozes-Santos A., Bobermin L.D., Latini A., Wajner M., Souza D.O., Gonçalves C.-A., Gottfried C. Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1. PLoS One 2013, 8. 10.1371/journal.pone.0064372.
    • (2013) PLoS One , vol.8
    • Quincozes-Santos, A.1    Bobermin, L.D.2    Latini, A.3    Wajner, M.4    Souza, D.O.5    Gonçalves, C.-A.6    Gottfried, C.7
  • 66
    • 84902991801 scopus 로고    scopus 로고
    • Guanosine protects C6 astroglial cells against azide-induced oxidative damage: a putative role of heme oxygenase 1
    • Quincozes-Santos A., Bobermin L.D., Souza D.G., Bellaver B., Gonçalves C.-A., Souza D.O. Guanosine protects C6 astroglial cells against azide-induced oxidative damage: a putative role of heme oxygenase 1. J. Neurochem. 2014, 130:61-74. 10.1111/jnc.12694.
    • (2014) J. Neurochem. , vol.130 , pp. 61-74
    • Quincozes-Santos, A.1    Bobermin, L.D.2    Souza, D.G.3    Bellaver, B.4    Gonçalves, C.-A.5    Souza, D.O.6
  • 68
    • 84880385970 scopus 로고    scopus 로고
    • Resveratrol, from experimental data to nutritional evidence: the emergence of a new food ingredient
    • Raederstorff D., Kunz I., Schwager J. Resveratrol, from experimental data to nutritional evidence: the emergence of a new food ingredient. Ann. N. Y. Acad. Sci. 2013, 1290:136-141. 10.1111/nyas.12147.
    • (2013) Ann. N. Y. Acad. Sci. , vol.1290 , pp. 136-141
    • Raederstorff, D.1    Kunz, I.2    Schwager, J.3
  • 69
    • 0344549778 scopus 로고    scopus 로고
    • Suppression of ammonia-induced astrocyte swelling by cyclosporin A
    • Rama Rao K.V., Chen M., Simard J.M., Norenberg M.D. Suppression of ammonia-induced astrocyte swelling by cyclosporin A. J. Neurosci. Res. 2003, 74:891-897. 10.1002/jnr.10755.
    • (2003) J. Neurosci. Res. , vol.74 , pp. 891-897
    • Rama Rao, K.V.1    Chen, M.2    Simard, J.M.3    Norenberg, M.D.4
  • 71
    • 84902548315 scopus 로고    scopus 로고
    • Role of glutamate transporters in redox homeostasis of the brain
    • Robert S.M., Ogunrinu-Babarinde T., Holt K.T., Sontheimer H. Role of glutamate transporters in redox homeostasis of the brain. Neurochem. Int. 2014, 73:181-191. 10.1016/j.neuint.2014.01.001.
    • (2014) Neurochem. Int. , vol.73 , pp. 181-191
    • Robert, S.M.1    Ogunrinu-Babarinde, T.2    Holt, K.T.3    Sontheimer, H.4
  • 72
    • 33646824320 scopus 로고    scopus 로고
    • Effect of ammonia on astrocytic glutamate uptake/release mechanisms
    • Rose C. Effect of ammonia on astrocytic glutamate uptake/release mechanisms. J. Neurochem. 2006, 97:11-15. 10.1111/j.1471-4159.2006.03796.x.
    • (2006) J. Neurochem. , vol.97 , pp. 11-15
    • Rose, C.1
  • 73
    • 20444366546 scopus 로고    scopus 로고
    • Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH
    • Rose C., Kresse W., Kettenmann H. Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH. J. Biol. Chem. 2005, 280:20937-20944. 10.1074/jbc.M412448200.
    • (2005) J. Biol. Chem. , vol.280 , pp. 20937-20944
    • Rose, C.1    Kresse, W.2    Kettenmann, H.3
  • 74
    • 77953711040 scopus 로고    scopus 로고
    • Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1
    • Sakata Y., Zhuang H., Kwansa H., Koehler R.C., Doré S. Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1. Exp. Neurol. 2010, 224:325-329. 10.1016/j.expneurol.2010.03.032.
    • (2010) Exp. Neurol. , vol.224 , pp. 325-329
    • Sakata, Y.1    Zhuang, H.2    Kwansa, H.3    Koehler, R.C.4    Doré, S.5
  • 75
    • 58149472202 scopus 로고    scopus 로고
    • 2+-dependent glutamate release
    • 2+-dependent glutamate release. Neuroscience 2009, 158:253-259. 10.1016/j.neuroscience.2008.03.039.
    • (2009) Neuroscience , vol.158 , pp. 253-259
    • Santello, M.1    Volterra, A.2
  • 78
    • 0036830073 scopus 로고    scopus 로고
    • Glutamine synthetase enhances the clearance of extracellular glutamate by the neural retina
    • Shaked I., Ben-Dror I., Vardimon L. Glutamine synthetase enhances the clearance of extracellular glutamate by the neural retina. J. Neurochem. 2002, 83:574-580.
    • (2002) J. Neurochem. , vol.83 , pp. 574-580
    • Shaked, I.1    Ben-Dror, I.2    Vardimon, L.3
  • 79
    • 80053123112 scopus 로고    scopus 로고
    • Resveratrol prevents oxidative stress and inhibition of Na(+)K(+)-ATPase activity induced by transient global cerebral ischemia in rats
    • Simão F., Matté A., Matté C., Soares F.M.S., Wyse A.T.S., Netto C.A., Salbego C.G. Resveratrol prevents oxidative stress and inhibition of Na(+)K(+)-ATPase activity induced by transient global cerebral ischemia in rats. J. Nutr. Biochem. 2011, 22:921-928. 10.1016/j.jnutbio.2010.07.013.
    • (2011) J. Nutr. Biochem. , vol.22 , pp. 921-928
    • Simão, F.1    Matté, A.2    Matté, C.3    Soares, F.M.S.4    Wyse, A.T.S.5    Netto, C.A.6    Salbego, C.G.7
  • 80
    • 84884884530 scopus 로고    scopus 로고
    • Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1
    • Son Y., Lee J.H., Chung H.-T., Pae H.-O. Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1. Oxid. Med. Cell. Longev. 2013, 2013:639541. 10.1155/2013/639541.
    • (2013) Oxid. Med. Cell. Longev. , vol.2013 , pp. 639541
    • Son, Y.1    Lee, J.H.2    Chung, H.-T.3    Pae, H.-O.4
  • 83
    • 0026516232 scopus 로고
    • Ammonia and related amino acids in the pathogenesis of brain edema in acute ischemic liver failure in rats
    • Swain M., Butterworth R.F., Blei A.T. Ammonia and related amino acids in the pathogenesis of brain edema in acute ischemic liver failure in rats. Hepatol. Baltim. Md 1992, 15:449-453.
    • (1992) Hepatol. Baltim. Md , vol.15 , pp. 449-453
    • Swain, M.1    Butterworth, R.F.2    Blei, A.T.3
  • 84
    • 54949143147 scopus 로고    scopus 로고
    • Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders: regulating HO-1 in the CNS
    • Syapin P.J. Regulation of haeme oxygenase-1 for treatment of neuroinflammation and brain disorders: regulating HO-1 in the CNS. Br. J. Pharmacol. 2009, 155:623-640. 10.1038/bjp.2008.342.
    • (2009) Br. J. Pharmacol. , vol.155 , pp. 623-640
    • Syapin, P.J.1
  • 85
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?
    • Trotti D., Danbolt N.C., Volterra A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?. Trends Pharmacol. Sci. 1998, 19:328-334.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 87
    • 84884692118 scopus 로고    scopus 로고
    • The activation of HO-1/Nrf-2 contributes to the protective effects of diallyl disulfide (DADS) against ethanol-induced oxidative stress
    • Zeng T., Zhang C.-L., Song F.-Y., Zhao X.-L., Yu L.-H., Zhu Z.-P., Xie K.-Q. The activation of HO-1/Nrf-2 contributes to the protective effects of diallyl disulfide (DADS) against ethanol-induced oxidative stress. Biochim. Biophys. Acta 2013, 1830:4848-4859. 10.1016/j.bbagen.2013.06.028.
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 4848-4859
    • Zeng, T.1    Zhang, C.-L.2    Song, F.-Y.3    Zhao, X.-L.4    Yu, L.-H.5    Zhu, Z.-P.6    Xie, K.-Q.7
  • 88
    • 77249122078 scopus 로고    scopus 로고
    • Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons
    • Zou J., Wang Y.-X., Dou F.-F., Lü H.-Z., Ma Z.-W., Lu P.-H., Xu X.-M. Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons. Neurochem. Int. 2010, 56:577-584. 10.1016/j.neuint.2009.12.021.
    • (2010) Neurochem. Int. , vol.56 , pp. 577-584
    • Zou, J.1    Wang, Y.-X.2    Dou, F.-F.3    Lü, H.-Z.4    Ma, Z.-W.5    Lu, P.-H.6    Xu, X.-M.7


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