메뉴 건너뛰기




Volumn 79, Issue , 2015, Pages 78-90

Ischemic preconditioning protects hippocampal pyramidal neurons from transient ischemic injury via the attenuation of oxidative damage through upregulating heme oxygenase-1

Author keywords

Delayed neuronal death; Heme oxygenase 1; Ischemiareperfusion; Ischemic preconditioning; Oxidative stress

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; HEME OXYGENASE 1; OXYGENASE INHIBITOR; SUPEROXIDE; UNCLASSIFIED DRUG; ZINC PROTOPORPHYRIN IX;

EID: 84919601146     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.11.022     Document Type: Article
Times cited : (35)

References (81)
  • 2
    • 33244486107 scopus 로고    scopus 로고
    • Effect of ischemic preconditioning on cerebral blood flow after subsequent lethal ischemia in gerbils
    • H. Nakamura, T. Katsumata, Y. Nishiyama, T. Otori, K. Katsura, and Y. Katayama Effect of ischemic preconditioning on cerebral blood flow after subsequent lethal ischemia in gerbils Life Sci. 78 2006 1713 1719
    • (2006) Life Sci. , vol.78 , pp. 1713-1719
    • Nakamura, H.1    Katsumata, T.2    Nishiyama, Y.3    Otori, T.4    Katsura, K.5    Katayama, Y.6
  • 3
    • 1842614423 scopus 로고    scopus 로고
    • Putative endogenous mediators of preconditioning-induced ischemic tolerance in rat brain identified by genomic and proteomic analysis
    • V.K. Dhodda, K.A. Sailor, K.K. Bowen, and R. Vemuganti Putative endogenous mediators of preconditioning-induced ischemic tolerance in rat brain identified by genomic and proteomic analysis J. Neurochem. 89 2004 73 89
    • (2004) J. Neurochem. , vol.89 , pp. 73-89
    • Dhodda, V.K.1    Sailor, K.A.2    Bowen, K.K.3    Vemuganti, R.4
  • 4
    • 33846635975 scopus 로고    scopus 로고
    • Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: A speculative synthesis
    • M.P. Stenzel-Poore, S.L. Stevens, J.S. King, and R.P. Simon Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis Stroke 38 2007 680 685
    • (2007) Stroke , vol.38 , pp. 680-685
    • Stenzel-Poore, M.P.1    Stevens, S.L.2    King, J.S.3    Simon, R.P.4
  • 5
    • 35248851986 scopus 로고    scopus 로고
    • Pathway and gene ontology based analysis of gene expression in a rat model of cerebral ischemic tolerance
    • Z. Feng, D.P. Davis, R. Sasik, H.H. Patel, J.C. Drummond, and P.M. Patel Pathway and gene ontology based analysis of gene expression in a rat model of cerebral ischemic tolerance Brain Res. 1177 2007 103 123
    • (2007) Brain Res. , vol.1177 , pp. 103-123
    • Feng, Z.1    Davis, D.P.2    Sasik, R.3    Patel, H.H.4    Drummond, J.C.5    Patel, P.M.6
  • 6
    • 0034468736 scopus 로고    scopus 로고
    • Role of reactive oxygen species (ROS) in apoptosis induction
    • H.U. Simon, A. Haj-Yehia, and F. Levi-Schaffer Role of reactive oxygen species (ROS) in apoptosis induction Apoptosis 5 2000 415 418
    • (2000) Apoptosis , vol.5 , pp. 415-418
    • Simon, H.U.1    Haj-Yehia, A.2    Levi-Schaffer, F.3
  • 7
    • 0030841350 scopus 로고    scopus 로고
    • Protein oxidation in aging, disease, and oxidative stress
    • B.S. Berlett, and E.R. Stadtman Protein oxidation in aging, disease, and oxidative stress J. Biol. Chem. 272 1997 20313 20316
    • (1997) J. Biol. Chem. , vol.272 , pp. 20313-20316
    • Berlett, B.S.1    Stadtman, E.R.2
  • 8
    • 4444237686 scopus 로고    scopus 로고
    • Role of oxidative stress in neurodegeneration: Recent developments in assay methods for oxidative stress and nutraceutical antioxidants
    • K. Cui, X. Luo, K. Xu, and M.R. Ven Murthy Role of oxidative stress in neurodegeneration: recent developments in assay methods for oxidative stress and nutraceutical antioxidants Prog. Neuropsychopharmacol. Biol. Psychiatry 28 2004 771 799
    • (2004) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.28 , pp. 771-799
    • Cui, K.1    Luo, X.2    Xu, K.3    Ven Murthy, M.R.4
  • 9
    • 0141849864 scopus 로고    scopus 로고
    • Ether fraction of methanol extracts of Gastrodia elata, medicinal herb protects against neuronal cell damage after transient global ischemia in gerbils
    • H.J. Kim, S.R. Lee, and K.D. Moon Ether fraction of methanol extracts of Gastrodia elata, medicinal herb protects against neuronal cell damage after transient global ischemia in gerbils Phytother. Res. 17 2003 909 912
    • (2003) Phytother. Res. , vol.17 , pp. 909-912
    • Kim, H.J.1    Lee, S.R.2    Moon, K.D.3
  • 10
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • R. Tenhunen, H.S. Marver, and R. Schmid The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase Proc. Natl. Acad. Sci. USA 61 1968 748 755
    • (1968) Proc. Natl. Acad. Sci. USA , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 11
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
    • S.W. Ryter, J. Alam, and A.M. Choi Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications Physiol. Rev. 86 2006 583 650
    • (2006) Physiol. Rev. , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.3
  • 12
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: A regulator of second messenger gases
    • M.D. Maines The heme oxygenase system: a regulator of second messenger gases Annu. Rev. Pharmacol. Toxicol. 37 1997 517 554
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 14
    • 0030188587 scopus 로고    scopus 로고
    • Heme oxygenase-1: Function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury
    • A.M. Choi, and J. Alam Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury Am. J. Respir. Cell. Mol. Biol. 15 1996 9 19
    • (1996) Am. J. Respir. Cell. Mol. Biol. , vol.15 , pp. 9-19
    • Choi, A.M.1    Alam, J.2
  • 16
    • 33846987890 scopus 로고    scopus 로고
    • Preconditioning with hyperbaric oxygen induces tolerance against oxidative injury via increased expression of heme oxygenase-1 in primary cultured spinal cord neurons
    • Q. Li, J. Li, L. Zhang, B. Wang, and L. Xiong Preconditioning with hyperbaric oxygen induces tolerance against oxidative injury via increased expression of heme oxygenase-1 in primary cultured spinal cord neurons Life Sci. 80 2007 1087 1093
    • (2007) Life Sci. , vol.80 , pp. 1087-1093
    • Li, Q.1    Li, J.2    Zhang, L.3    Wang, B.4    Xiong, L.5
  • 17
    • 0032972686 scopus 로고    scopus 로고
    • Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice
    • N. Panahian, M. Yoshiura, and M.D. Maines Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice J. Neurochem. 72 1999 1187 1203
    • (1999) J. Neurochem. , vol.72 , pp. 1187-1203
    • Panahian, N.1    Yoshiura, M.2    Maines, M.D.3
  • 18
    • 67649628772 scopus 로고    scopus 로고
    • Heme oxygenase-1 and neurodegeneration: Expanding frontiers of engagement
    • H.M. Schipper, W. Song, H. Zukor, J.R. Hascalovici, and D. Zeligman Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement J. Neurochem. 110 2009 469 485
    • (2009) J. Neurochem. , vol.110 , pp. 469-485
    • Schipper, H.M.1    Song, W.2    Zukor, H.3    Hascalovici, J.R.4    Zeligman, D.5
  • 20
    • 84870396636 scopus 로고    scopus 로고
    • Participation of protein kinase C in the activation of Nrf2 signaling by ischemic preconditioning in the isolated rabbit heart
    • X. Zhang, Z. Xiao, J. Yao, G. Zhao, X. Fa, and J. Niu Participation of protein kinase C in the activation of Nrf2 signaling by ischemic preconditioning in the isolated rabbit heart Mol. Cell. Biochem. 372 2013 169 179
    • (2013) Mol. Cell. Biochem. , vol.372 , pp. 169-179
    • Zhang, X.1    Xiao, Z.2    Yao, J.3    Zhao, G.4    Fa, X.5    Niu, J.6
  • 22
    • 0037371658 scopus 로고    scopus 로고
    • Expression of haem oxygenase in cirrhotic rat liver
    • C.L. Wei, K.H. Lee, H.E. Khoo, and W.M. Hon Expression of haem oxygenase in cirrhotic rat liver J. Pathol. 199 2003 324 334
    • (2003) J. Pathol. , vol.199 , pp. 324-334
    • Wei, C.L.1    Lee, K.H.2    Khoo, H.E.3    Hon, W.M.4
  • 23
    • 84876992081 scopus 로고    scopus 로고
    • Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice
    • I. Perez-de-Puig, A. Martin, R. Gorina, X. de la Rosa, E. Martinez, and A.M. Planas Induction of hemeoxygenase-1 expression after inhibition of hemeoxygenase activity promotes inflammation and worsens ischemic brain damage in mice Neuroscience 243 2013 22 32
    • (2013) Neuroscience , vol.243 , pp. 22-32
    • Perez-De-Puig, I.1    Martin, A.2    Gorina, R.3    De La Rosa, X.4    Martinez, E.5    Planas, A.M.6
  • 24
    • 0034714392 scopus 로고    scopus 로고
    • A high affinity fluorescent marker for the localization of neuronal degeneration
    • L.C. Schmued, K.J. Hopkins, and B Fluoro-Jade a high affinity fluorescent marker for the localization of neuronal degeneration Brain Res. 874 2000 123 130
    • (2000) Brain Res. , vol.874 , pp. 123-130
    • Schmued, L.C.1    Hopkins, K.J.2    Fluoro-Jade, B.3
  • 25
    • 0034889080 scopus 로고    scopus 로고
    • 4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia
    • E. McKracken, D.I. Graham, M. Nilsen, J. Stewart, J.A. Nicoll, and K. Horsburgh 4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia Brain Pathol. 11 2001 414 421
    • (2001) Brain Pathol. , vol.11 , pp. 414-421
    • McKracken, E.1    Graham, D.I.2    Nilsen, M.3    Stewart, J.4    Nicoll, J.A.5    Horsburgh, K.6
  • 27
    • 0344298999 scopus 로고    scopus 로고
    • Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo
    • M.H. Won, T.C. Kang, G.S. Jeon, J.C. Lee, D.Y. Kim, E.M. Choi, K.H. Lee, C.D. Choi, M.H. Chung, and S.S. Cho Immunohistochemical detection of oxidative DNA damage induced by ischemia-reperfusion insults in gerbil hippocampus in vivo Brain Res. 836 1999 70 78
    • (1999) Brain Res. , vol.836 , pp. 70-78
    • Won, M.H.1    Kang, T.C.2    Jeon, G.S.3    Lee, J.C.4    Kim, D.Y.5    Choi, E.M.6    Lee, K.H.7    Choi, C.D.8    Chung, M.H.9    Cho, S.S.10
  • 28
    • 0023831291 scopus 로고
    • Resolution of the rat brain heme oxygenase activity: Absence of a detectable amount of the inducible form (HO-1)
    • G.M. Trakshel, R.K. Kutty, and M.D. Maines Resolution of the rat brain heme oxygenase activity: absence of a detectable amount of the inducible form (HO-1) Arch. Biochem. Biophys. 260 1988 732 739
    • (1988) Arch. Biochem. Biophys. , vol.260 , pp. 732-739
    • Trakshel, G.M.1    Kutty, R.K.2    Maines, M.D.3
  • 29
    • 79251594784 scopus 로고    scopus 로고
    • Dynamic changes of heme oxygenase-1 in the hippocampus of rats after acute carbon monoxide poisoning
    • L. Guan, Y.L. Zhang, T. Wen, X.F. Wang, M.X. Zhu, and J.Y. Zhao Dynamic changes of heme oxygenase-1 in the hippocampus of rats after acute carbon monoxide poisoning Arch. Environ. Contam. Toxicol. 60 2011 165 172
    • (2011) Arch. Environ. Contam. Toxicol. , vol.60 , pp. 165-172
    • Guan, L.1    Zhang, Y.L.2    Wen, T.3    Wang, X.F.4    Zhu, M.X.5    Zhao, J.Y.6
  • 30
    • 33744509306 scopus 로고    scopus 로고
    • Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus
    • Q. Wang, K.D. Tompkins, A. Simonyi, R.J. Korthuis, A.Y. Sun, and G.Y. Sun Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus Brain Res. 1090 2006 182 189
    • (2006) Brain Res. , vol.1090 , pp. 182-189
    • Wang, Q.1    Tompkins, K.D.2    Simonyi, A.3    Korthuis, R.J.4    Sun, A.Y.5    Sun, G.Y.6
  • 31
    • 77955475115 scopus 로고    scopus 로고
    • Hypothyroid state does not protect but delays neuronal death in the hippocampal CA1 region following transient cerebral ischemia: Focus on oxidative stress and gliosis
    • C.H. Lee, K.Y. Yoo, I.K. Hwang, J.H. Choi, O.K. Park, H. Li, I.J. Kang, Y.G. Kwon, Y.M. Kim, and M.H. Won Hypothyroid state does not protect but delays neuronal death in the hippocampal CA1 region following transient cerebral ischemia: focus on oxidative stress and gliosis J. Neurosci. Res. 88 2010 2661 2668
    • (2010) J. Neurosci. Res. , vol.88 , pp. 2661-2668
    • Lee, C.H.1    Yoo, K.Y.2    Hwang, I.K.3    Choi, J.H.4    Park, O.K.5    Li, H.6    Kang, I.J.7    Kwon, Y.G.8    Kim, Y.M.9    Won, M.H.10
  • 33
    • 0032881979 scopus 로고    scopus 로고
    • Attenuated stroke severity after prodromal TIA: A role for ischemic tolerance in the brain?
    • M. Weih, K. Kallenberg, A. Bergk, U. Dirnagl, L. Harms, K.D. Wernecke, and K.M. Einhaupl Attenuated stroke severity after prodromal TIA: a role for ischemic tolerance in the brain? Stroke 30 1999 1851 1854
    • (1999) Stroke , vol.30 , pp. 1851-1854
    • Weih, M.1    Kallenberg, K.2    Bergk, A.3    Dirnagl, U.4    Harms, L.5    Wernecke, K.D.6    Einhaupl, K.M.7
  • 35
    • 33846159435 scopus 로고    scopus 로고
    • Ischaemic preconditioning of the brain, mechanisms and applications
    • H.J. Steiger, and D. Hanggi Ischaemic preconditioning of the brain, mechanisms and applications Acta Neurochir. (Wien) 149 2007 1 10
    • (2007) Acta Neurochir. (Wien) , vol.149 , pp. 1-10
    • Steiger, H.J.1    Hanggi, D.2
  • 36
    • 0026096485 scopus 로고
    • Locomotor hyperactivity and hippocampal CA1 injury after transient forebrain ischemia of gerbils
    • T. Kuroiwa, P. Bonnekoh, and K.A. Hossmann Locomotor hyperactivity and hippocampal CA1 injury after transient forebrain ischemia of gerbils Neurosci. Lett. 122 1991 141 144
    • (1991) Neurosci. Lett. , vol.122 , pp. 141-144
    • Kuroiwa, T.1    Bonnekoh, P.2    Hossmann, K.A.3
  • 37
    • 0023785022 scopus 로고
    • Motor activity changes following cerebral ischemia in gerbils are correlated with the degree of neuronal degeneration in hippocampus
    • S.C. Gerhardt, and C.A. Boast Motor activity changes following cerebral ischemia in gerbils are correlated with the degree of neuronal degeneration in hippocampus Behav. Neurosci. 102 301-303 1988 328
    • (1988) Behav. Neurosci. , vol.102 , Issue.301-303 , pp. 328
    • Gerhardt, S.C.1    Boast, C.A.2
  • 38
    • 0028156767 scopus 로고
    • Changes in locomotor activity and passive avoidance task performance induced by cerebral ischemia in Mongolian gerbils
    • Y. Karasawa, H. Araki, and S. Otomo Changes in locomotor activity and passive avoidance task performance induced by cerebral ischemia in Mongolian gerbils Stroke 25 1994 645 650
    • (1994) Stroke , vol.25 , pp. 645-650
    • Karasawa, Y.1    Araki, H.2    Otomo, S.3
  • 39
    • 0027944666 scopus 로고
    • Hemeoxygenase expression after reversible ischemia of rat brain
    • W. Paschen, A. Uto, B. Djuricic, and J. Schmitt Hemeoxygenase expression after reversible ischemia of rat brain Neurosci. Lett. 180 1994 5 8
    • (1994) Neurosci. Lett. , vol.180 , pp. 5-8
    • Paschen, W.1    Uto, A.2    Djuricic, B.3    Schmitt, J.4
  • 41
    • 0028116747 scopus 로고
    • Increased expression of heme oxygenase mRNA in rat brain following transient forebrain ischemia
    • A. Takeda, H. Onodera, A. Sugimoto, Y. Itoyama, K. Kogure, and S. Shibahara Increased expression of heme oxygenase mRNA in rat brain following transient forebrain ischemia Brain Res. 666 1994 120 124
    • (1994) Brain Res. , vol.666 , pp. 120-124
    • Takeda, A.1    Onodera, H.2    Sugimoto, A.3    Itoyama, Y.4    Kogure, K.5    Shibahara, S.6
  • 43
    • 0029973893 scopus 로고    scopus 로고
    • Long-term induction of haem oxygenase-1 (HSP-32) in astrocytes and microglia following transient focal brain ischaemia in the rat
    • J. Koistinaho, S. Miettinen, R. Keinanen, N. Vartiainen, R. Roivainen, and J.T. Laitinen Long-term induction of haem oxygenase-1 (HSP-32) in astrocytes and microglia following transient focal brain ischaemia in the rat Eur. J. Neurosci. 8 1996 2265 2272
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 2265-2272
    • Koistinaho, J.1    Miettinen, S.2    Keinanen, R.3    Vartiainen, N.4    Roivainen, R.5    Laitinen, J.T.6
  • 44
    • 34748892491 scopus 로고    scopus 로고
    • Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats
    • T.J. Moreira, A. Cebere, G. Cebers, C.G. Ostenson, S. Efendic, and S. Liljequist Reduced HO-1 protein expression is associated with more severe neurodegeneration after transient ischemia induced by cortical compression in diabetic Goto-Kakizaki rats J. Cereb. Blood Flow Metab. 27 2007 1710 1723
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 1710-1723
    • Moreira, T.J.1    Cebere, A.2    Cebers, G.3    Ostenson, C.G.4    Efendic, S.5    Liljequist, S.6
  • 45
    • 84884493497 scopus 로고    scopus 로고
    • Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke
    • A. Alfieri, S. Srivastava, R.C. Siow, D. Cash, M. Modo, M.R. Duchen, P.A. Fraser, S.C. Williams, and G.E. Mann Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood-brain barrier disruption and neurological deficits in stroke Free Radic. Biol. Med. 65 2013 1012 1022
    • (2013) Free Radic. Biol. Med. , vol.65 , pp. 1012-1022
    • Alfieri, A.1    Srivastava, S.2    Siow, R.C.3    Cash, D.4    Modo, M.5    Duchen, M.R.6    Fraser, P.A.7    Williams, S.C.8    Mann, G.E.9
  • 47
    • 0027358877 scopus 로고
    • Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage
    • J. Balla, H.S. Jacob, G. Balla, K. Nath, J.W. Eaton, and G.M. Vercellotti Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage Proc. Natl. Acad. Sci. USA 90 1993 9285 9289
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9285-9289
    • Balla, J.1    Jacob, H.S.2    Balla, G.3    Nath, K.4    Eaton, J.W.5    Vercellotti, G.M.6
  • 48
    • 33847291917 scopus 로고    scopus 로고
    • Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation
    • X. Wang, Y. Wang, H.P. Kim, K. Nakahira, S.W. Ryter, and A.M. Choi Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation J. Biol. Chem. 282 2007 1718 1726
    • (2007) J. Biol. Chem. , vol.282 , pp. 1718-1726
    • Wang, X.1    Wang, Y.2    Kim, H.P.3    Nakahira, K.4    Ryter, S.W.5    Choi, A.M.6
  • 50
    • 70349730056 scopus 로고    scopus 로고
    • Low doses of carbon monoxide protect against experimental focal brain ischemia
    • E. Zeynalov, and S. Dore Low doses of carbon monoxide protect against experimental focal brain ischemia Neurotox. Res. 15 2009 133 137
    • (2009) Neurotox. Res. , vol.15 , pp. 133-137
    • Zeynalov, E.1    Dore, S.2
  • 51
    • 0023132858 scopus 로고
    • Bilirubin is an antioxidant of possible physiological importance
    • R. Stocker, Y. Yamamoto, A.F. McDonagh, A.N. Glazer, and B.N. Ames Bilirubin is an antioxidant of possible physiological importance Science 235 1987 1043 1046
    • (1987) Science , vol.235 , pp. 1043-1046
    • Stocker, R.1    Yamamoto, Y.2    McDonagh, A.F.3    Glazer, A.N.4    Ames, B.N.5
  • 53
    • 0025969686 scopus 로고
    • Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron
    • R.S. Eisenstein, D. Garcia-Mayol, W. Pettingell, and H.N. Munro Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron Proc. Natl. Acad. Sci. USA 88 1991 688 692
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 688-692
    • Eisenstein, R.S.1    Garcia-Mayol, D.2    Pettingell, W.3    Munro, H.N.4
  • 56
    • 67649472406 scopus 로고    scopus 로고
    • Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia
    • E. Zeynalov, Z.A. Shah, R.C. Li, and S. Dore Heme oxygenase 1 is associated with ischemic preconditioning-induced protection against brain ischemia Neurobiol. Dis. 35 2009 264 269
    • (2009) Neurobiol. Dis. , vol.35 , pp. 264-269
    • Zeynalov, E.1    Shah, Z.A.2    Li, R.C.3    Dore, S.4
  • 58
    • 0027511579 scopus 로고
    • Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus
    • M.B. Jorgensen, B.R. Finsen, M.B. Jensen, B. Castellano, N.H. Diemer, and J. Zimmer Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus Exp. Neurol. 120 1993 70 88
    • (1993) Exp. Neurol. , vol.120 , pp. 70-88
    • Jorgensen, M.B.1    Finsen, B.R.2    Jensen, M.B.3    Castellano, B.4    Diemer, N.H.5    Zimmer, J.6
  • 61
    • 66449130960 scopus 로고    scopus 로고
    • Regulation of innate immune responses in the brain
    • S. Rivest Regulation of innate immune responses in the brain Nat. Rev. Immunol. 9 2009 429 439
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 429-439
    • Rivest, S.1
  • 62
    • 60149098421 scopus 로고    scopus 로고
    • Debris clearance by microglia: An essential link between degeneration and regeneration
    • H. Neumann, M.R. Kotter, and R.J. Franklin Debris clearance by microglia: an essential link between degeneration and regeneration Brain 132 2009 288 295
    • (2009) Brain , vol.132 , pp. 288-295
    • Neumann, H.1    Kotter, M.R.2    Franklin, R.J.3
  • 65
    • 0038205804 scopus 로고    scopus 로고
    • Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury
    • R. Gupta, M. Singh, and A. Sharma Neuroprotective effect of antioxidants on ischaemia and reperfusion-induced cerebral injury Pharmacol. Res. 48 2003 209 215
    • (2003) Pharmacol. Res. , vol.48 , pp. 209-215
    • Gupta, R.1    Singh, M.2    Sharma, A.3
  • 66
    • 77958555016 scopus 로고    scopus 로고
    • Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat
    • L. Raz, Q.G. Zhang, C.F. Zhou, D. Han, P. Gulati, L.C. Yang, F. Yang, R.M. Wang, and D.W. Brann Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat PLoS One 5 2010 e12606
    • (2010) PLoS One , vol.5 , pp. 12606
    • Raz, L.1    Zhang, Q.G.2    Zhou, C.F.3    Han, D.4    Gulati, P.5    Yang, L.C.6    Yang, F.7    Wang, R.M.8    Brann, D.W.9
  • 68
    • 77952675659 scopus 로고    scopus 로고
    • Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis
    • P. Deb, S. Sharma, and K.M. Hassan Pathophysiologic mechanisms of acute ischemic stroke: an overview with emphasis on therapeutic significance beyond thrombolysis Pathophysiology 17 2010 197 218
    • (2010) Pathophysiology , vol.17 , pp. 197-218
    • Deb, P.1    Sharma, S.2    Hassan, K.M.3
  • 69
    • 77449152992 scopus 로고    scopus 로고
    • Oxidative stress and its role in the pathogenesis of ischaemic stroke
    • C.L. Allen, and U. Bayraktutan Oxidative stress and its role in the pathogenesis of ischaemic stroke Int. J. Stroke 4 2009 461 470
    • (2009) Int. J. Stroke , vol.4 , pp. 461-470
    • Allen, C.L.1    Bayraktutan, U.2
  • 70
    • 79952184388 scopus 로고    scopus 로고
    • Cerebral reactive oxygen species assessed by electron spin resonance spectroscopy in the initial stage of ischemia-reperfusion are not associated with hypothermic neuroprotection
    • T. Kunimatsu, K. Kobayashi, A. Yamashita, T. Yamamoto, and M.C. Lee Cerebral reactive oxygen species assessed by electron spin resonance spectroscopy in the initial stage of ischemia-reperfusion are not associated with hypothermic neuroprotection J. Clin. Neurosci. 18 2011 545 548
    • (2011) J. Clin. Neurosci. , vol.18 , pp. 545-548
    • Kunimatsu, T.1    Kobayashi, K.2    Yamashita, A.3    Yamamoto, T.4    Lee, M.C.5
  • 73
    • 84861682913 scopus 로고    scopus 로고
    • Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro
    • C. Mancuso, E. Barone, P. Guido, F. Miceli, F. Di Domenico, M. Perluigi, R. Santangelo, and P. Preziosi Inhibition of lipid peroxidation and protein oxidation by endogenous and exogenous antioxidants in rat brain microsomes in vitro Neurosci. Lett. 518 2012 101 105
    • (2012) Neurosci. Lett. , vol.518 , pp. 101-105
    • Mancuso, C.1    Barone, E.2    Guido, P.3    Miceli, F.4    Di Domenico, F.5    Perluigi, M.6    Santangelo, R.7    Preziosi, P.8
  • 74
    • 0035970836 scopus 로고    scopus 로고
    • The alterations of N-methyl-D-aspartate receptor expressions and oxidative DNA damage in the CA1 area at the early time after ischemia-reperfusion insult
    • M.H. Won, T. Kang, S. Park, G. Jeon, Y. Kim, J.H. Seo, E. Choi, M. Chung, and S.S. Cho The alterations of N-methyl-D-aspartate receptor expressions and oxidative DNA damage in the CA1 area at the early time after ischemia-reperfusion insult Neurosci. Lett. 301 2001 139 142
    • (2001) Neurosci. Lett. , vol.301 , pp. 139-142
    • Won, M.H.1    Kang, T.2    Park, S.3    Jeon, G.4    Kim, Y.5    Seo, J.H.6    Choi, E.7    Chung, M.8    Cho, S.S.9
  • 76
    • 84879504006 scopus 로고    scopus 로고
    • Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling
    • R. Wang, J. Tu, Q. Zhang, X. Zhang, Y. Zhu, W. Ma, C. Cheng, D.W. Brann, and F. Yang Genistein attenuates ischemic oxidative damage and behavioral deficits via eNOS/Nrf2/HO-1 signaling Hippocampus 23 2013 634 647
    • (2013) Hippocampus , vol.23 , pp. 634-647
    • Wang, R.1    Tu, J.2    Zhang, Q.3    Zhang, X.4    Zhu, Y.5    Ma, W.6    Cheng, C.7    Brann, D.W.8    Yang, F.9
  • 77
    • 67650729358 scopus 로고    scopus 로고
    • Lipid peroxidation: Physiological levels and dual biological effects
    • E. Niki Lipid peroxidation: physiological levels and dual biological effects Free Radic. Biol. Med. 47 2009 469 484
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 469-484
    • Niki, E.1
  • 78
    • 0035370344 scopus 로고    scopus 로고
    • Differential effects of calcium-dependent and calcium-independent phospholipase A(2) inhibitors on kainate-induced neuronal injury in rat hippocampal slices
    • X.R. Lu, W.Y. Ong, B. Halliwell, L.A. Horrocks, and A.A. Farooqui Differential effects of calcium-dependent and calcium-independent phospholipase A(2) inhibitors on kainate-induced neuronal injury in rat hippocampal slices Free Radic. Biol. Med. 30 2001 1263 1273
    • (2001) Free Radic. Biol. Med. , vol.30 , pp. 1263-1273
    • Lu, X.R.1    Ong, W.Y.2    Halliwell, B.3    Horrocks, L.A.4    Farooqui, A.A.5
  • 79
    • 33846809497 scopus 로고    scopus 로고
    • Modulation of antioxidant gene expression by 4-hydroxynonenal: Atheroprotective role of the Nrf2/ARE transcription pathway
    • R.C. Siow, T. Ishii, and G.E. Mann Modulation of antioxidant gene expression by 4-hydroxynonenal: atheroprotective role of the Nrf2/ARE transcription pathway Redox Rep. 12 2007 11 15
    • (2007) Redox Rep. , vol.12 , pp. 11-15
    • Siow, R.C.1    Ishii, T.2    Mann, G.E.3
  • 80
    • 84876726968 scopus 로고    scopus 로고
    • Expression and antioxidation of Nrf2/ARE pathway in traumatic brain injury
    • Z.G. Cheng, G.D. Zhang, P.Q. Shi, and B.S. Du Expression and antioxidation of Nrf2/ARE pathway in traumatic brain injury Asian Pac. J. Trop. Med 6 2013 305 310
    • (2013) Asian Pac. J. Trop. Med , vol.6 , pp. 305-310
    • Cheng, Z.G.1    Zhang, G.D.2    Shi, P.Q.3    Du, B.S.4
  • 81
    • 84874633349 scopus 로고    scopus 로고
    • Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo
    • D.M. Miller, I.N. Singh, J.A. Wang, and E.D. Hall Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo Free Radic. Biol. Med. 57 2013 1 9
    • (2013) Free Radic. Biol. Med. , vol.57 , pp. 1-9
    • Miller, D.M.1    Singh, I.N.2    Wang, J.A.3    Hall, E.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.