Heme oxygenase 1: Another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule

Experimental Neurology

Volumn 225, Issue 2, 2010, Pages 237-239

  Bastianetto, Stéphane ^a   Quirion, Rémi ^a  

^a DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE BETA; EPICATECHIN; GLYCOGEN SYNTHASE KINASE 3BETA; HEME OXYGENASE 1; KAINIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE LKB1; RESVERATROL; SIRTUIN 1; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; STILBENE DERIVATIVE;

APOPTOSIS; BILIRUBIN BLOOD LEVEL; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFICACY; ENZYME INDUCTION; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; ISCHEMIA; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL; NEUROPROTECTION; NONHUMAN; NOTE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STROKE; UPREGULATION; ANIMAL; BRAIN; DRUG EFFECTS; METABOLISM;

ANIMALS; BRAIN; HEME OXYGENASE-1; NEURONS; NEUROPROTECTIVE AGENTS; STILBENES;

EID: 77956444535     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.06.019     Document Type: Note

References (44)

1. Albani D., Polito L., Batelli S., De Mauro S., Fracasso C., Martelli G., Colombo L., Manzoni C., Salmona M., Caccia S., Negro A., Forloni G. The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. J. Neurochem. 2009, 110:1445-1456.
2. Albani D., Polito L., Forloni G. Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: experimental and genetic evidence. J. Alzheimers Dis. 2010, 19:11-26.
3. Barañano D.E., Snyder S.H. Neural roles for heme oxygenase: contrasts to nitric oxide synthase. Proc. Natl Acad. Sci. USA 2001, 98:10996-11002.
4. Bastianetto S., Zheng W.H., Quirion R. Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons. Br. J. Pharmacol. 2000, 131:711-720.
5. Borra M.T., Smith B.C., Denu J.M. Mechanism of human SIRT1 activation by resveratrol. J. Biol. Chem. 2005, 280:17187-17195.
6. Campos-Esparza M.R., Sanchez-Gomez M.V., Matute C. Molecular mechanisms of neuroprotection by two natural antioxidant polyphenols. Cell Calcium 2009, 45:358-368.
7. Culmsee C., Monnig J., Kemp B.E., Mattson M.P. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. J. Mol. Neurosci. 2001, 17:45-58.
8. Das S., Tosaki A., Bagchi D., Maulik N., Das D.K. Resveratrol-mediated activation of cAMP response element-binding protein through adenosine A3 receptor by Akt-dependent and -independent pathways. J. Pharmacol. Exp. Ther. 2005, 314:762-769.
9. Dasgupta B., Milbrandt J. Resveratrol stimulates AMP kinase activity in neurons. Proc. Natl Acad. Sci. USA 2007, 104:7217-7222.
10. Feng Y., Wang X.P., Yang S.G., Wang Y.J., Zhang X., Du X.T., Sun X.X., Zhao M., Huang L., Liu R.T. Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation. Neurotoxicology 2009, 30:986-995.
11. Hammarström P., Jiang X., Hurshman A.R., Powers E.T., Kelly J.W. Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity. Proc. Natl Acad. Sci. USA 2002, 99(Suppl 4):16427-16432.
12. Han Y.S., Zheng W.H., Bastianetto S., Chabot J.G., Quirion R. Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C. Br. J. Pharmacol. 2004, 141:997-1005.
13. Han Y.S., Bastianetto S., Dumont Y., Quirion R. Specific plasma membrane binding sites for polyphenols, including resveratrol, in the rat brain. J. Pharmacol. Exp. Ther. 2006, 318:238-245.
14. Karuppagounder S.S., Pinto J.T., Xu H., Chen H.L., Beal M.F., Gibson G.E. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem. Int. 2009, 54:111-118.
15. Li R.C., Saleem S., Zhen G., Cao W., Zhuang H., Lee J., Smith A., Altruda F., Tolosano E., Doré S. Heme-hemopexin complex attenuates neuronal cell death and stroke damage. J. Cereb. Blood Flow Metab. 2009, 229:953-964.
16. Luchsinger J.A., Noble J.M., Scarmeas N. Diet and Alzheimer's disease. Curr. Neurol. Neurosci. Rep. 2007, 7:366-372.
17. Ma W., Yuan L., Yu H., Ding B., Xi Y., Feng J., Xiao R. Genistein as a neuroprotective antioxidant attenuates redox imbalance induced by beta-amyloid peptides 25-35 in PC12 cells. Int J Dev Neurosci. 2010, 28:289-295.
18. Maccarrone M., Lorenzon T., Guerrieri P., Agro A. Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity. Eur. J. Biochem. 1999, 265:27-34.
19. Marambaud P., Zhao H., Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-β peptides. J. Biol. Chem. 2005, 280:37377-37382.
20. Obisesan T.O., Hirsh R., Kosoko O., Carlson L.M., Parrott M. Moderate wine consumption is associated with decreased odds of developing age-related macular degeneration in NHANES-1. J. Am. Ger. Soc. 1998, 46:1-7.
21. Ogborne R.M., Rushworth S.A., O'Connell M.A. Epigallocatechin activates haemoxygenase-1 expression via protein kinase Cdelta and Nrf2. Biochem. Biophys. Res. Commun. 2008, 373:584-588.
22. Orgogozo J.M., Dartigues J.F., Lafont S., Letenneur L., Commenges D., Salomon R., Renaud S., Breteler M.B. Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area. Rev. Neurol. 1997, 153:185-192.
23. Pacholec M., Bleasdale J.E., Chrunyk B., Cunningham D., Flynn D., Garofalo R.S., Griffith D., Griffor M., Loulakis P., Pabst B., Qiu X., Stockman B., Thanabal V., Varghese A., Ward J., Withka J., Ahn K. SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1. J. Biol. Chem. 2010, 285:8340-8351.
24. Raval A.P., Dave K.R., Pérez-Pinzón M.A. Resveratrol mimics ischemic preconditioning in the brain. J. Cereb. Blood Flow Metab. 2006, 26:1141-1147.
25. Ritz M.F., Curin Y., Mendelowitsch A., Andriantsitohaina R. Acute treatment with red wine polyphenols protects from ischemia-induced excitotoxicity, energy failure and oxidative stress in rats. Brain Res. 2008, 1239:226-234.
26. Rivière C., Richard T., Vitrac X., Mérillon J.M., Valls J., Monti J.P. New polyphenols active on beta-amyloid aggregation. Bioorg. Med. Chem. Lett. 2008, 18:828-831.
27. Rushworth S.A., Ogborne R.M., Charalambos C.A., O'Connell M.A. Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. Biochem. Biophys. Res. Commun. 2006, 341:1007-1016.
28. Sakata Y., Zhuang H., Kwansa H., Koehler R.C., Doré S. Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1. Exp. Neurol. 2010, 224:325-329.
29. Saleem S., Zhuang H., Biswal S., Christen Y., Doré S. Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury. Stroke 2008, 39:3389-3396.
30. Schipper H.M., Gupta A., Szarek W.A. Suppression of glial HO-1 activity as a potential neurotherapeutic intervention in AD. Curr. Alzheimer Res. 2009, 6:424-430.
31. Schipper H.M., Song W., Zukor H., Hascalovici J.R., Zeligman D. Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement. J. Neurochem. 2009, 110:469-485.
32. Shah, Z.A., Li, R.C., Ahmad, A.S., Kensler, T.W., Yamamoto, M., Biswal, S., Doré, S., in press. The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway. J Cereb. Blood Flow Metab. doi:10.1038/jcbfm.2010.53.
33. Shibata R., Sato K., Pimentel D.R., Takemura Y., Kihara S., Ohashi K., Funahashi T., Ouchi N., Walsh K. Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. Nat. Med. 2005, 11:1096-1103.
34. Shin S.M., Cho I.J., Kim S.G. Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway. Mol. Pharmacol. 2009, 76:884-895.
35. Sinha K., Chaudhary G., Gupta Y.K. Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats. Life Sci. 2002, 71:655-665.
36. Song W., Su H., Song S., Paudel H.K., Schipper H.M. Over-expression of hemeoxygenase-1 promotes oxidative mitochondrial damage in rat astroglia. J. Cell. Physiol. 2006, 206:655-663.
37. Takahashi M., Doré S., Ferris C.D., Tomita T., Sawa A., Wolosker H., Borchelt D.R., Iwatsubo T., Kim S.H., Thinakaran G., Sisodia S.S., Snyder S.H. Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. Neuron 2000, 28:461-473.
38. Tang B.L. Resveratrol is neuroprotective because it is not a direct activator of Sirt1-A hypothesis. Brain Res. Bull. 2010, 81:359-361.
39. Vingtdeux V., Giliberto L., Zhao H., Chandakkar P., Wu Q., Simon J.E., Janle E.M., Lobo J., Ferruzzi M.G., Davies P., Marambaud P. AMP-activated protein kinase signalling activation by resveratrol modulates amyloid-beta peptide metabolism. J. Biol. Chem. 2010, 285:9100-9113.
40. Virgili M., Contestabile A. Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats. Neurosci. Lett. 2000, 281:123-126.
41. Wang Q., Xu J., Rottinghaus G.E., Simonyi A., Lubahn D., Sun G.Y., Sun A.Y. Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res. 2002, 958:439-447.
42. Yang C., Zhang X., Fan H., Liu Y. Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia. Brain Res. 2009, 1282:133-141.
43. Zamin L.L., Dillenburg-Pilla P., Argenta-Comiran R., Horn A.P., Simão F., Nassif M., Gerhardt D., Frozza R.L., Salbego C. Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: involvement of PI3-K pathway. Neurobiol. Dis. 2006, 24:170-182.
44. Zhang H., Schools G.P., Lei T., Wang W., Kimelberg H.K., Zhou M. Resveratrol attenuates early pyramidal neuron excitability impairment and death in acute rat hippocampal slices caused by oxygen-glucose deprivation. Exp. Neurol. 2008, 212:44-52.