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Volumn 20, Issue 36, 2013, Pages 4640-4645

Neuroprotection by resveratrol in diabetic neuropathy: Concepts & mechanisms

Author keywords

Diabetic neuropathy; Neuroprotection; NF B; Nrf2; Resveratrol; SIRT

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; NITRIC OXIDE; RESVERATROL; SIRTUIN 1; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

EID: 84887937515     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113209990151     Document Type: Article
Times cited : (46)

References (62)
  • 3
    • 4143110556 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of diabetic neuropathy
    • Vincent, A.M.; Russell, J.W.; Low, P.; Feldman, E.L. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev., 2004, 25(4), 612-628.
    • (2004) Endocr. Rev. , vol.25 , Issue.4 , pp. 612-628
    • Vincent, A.M.1    Russell, J.W.2    Low, P.3    Feldman, E.L.4
  • 5
    • 33746666631 scopus 로고    scopus 로고
    • Enhanced inflammatory response via activation of NF-kappaB in acute experimental diabetic neuropathy subjected to ischemiareperfusion injury
    • Wang, Y.; Schmeichel, A.M.; Iida, H.; Schmelzer, J.D.; Low, P.A. Enhanced inflammatory response via activation of NF-kappaB in acute experimental diabetic neuropathy subjected to ischemiareperfusion injury. J. Neurol. Sci., 2006, 247(1), 47-52.
    • (2006) J. Neurol. Sci. , vol.247 , Issue.1 , pp. 47-52
    • Wang, Y.1    Schmeichel, A.M.2    Iida, H.3    Schmelzer, J.D.4    Low, P.A.5
  • 6
    • 84865447807 scopus 로고    scopus 로고
    • Oxidative stress and diabetic neuropathy: Current status of antioxidants
    • Negi, G.; Kumar, A.; Joshi, R.P.; Ruby, P.K.; Sharma, S.S. Oxidative stress and diabetic neuropathy: current status of antioxidants IIOAB. J., 2011, 2(6), 71-78.
    • (2011) IIOAB J. , vol.2 , Issue.6 , pp. 71-78
    • Negi, G.1    Kumar, A.2    Joshi, R.P.3    Ruby, P.K.4    Sharma, S.S.5
  • 7
    • 79955482037 scopus 로고    scopus 로고
    • Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: Old perspective with a new angle
    • Negi, G.; Kumar, A.; Joshi, R.P.; Sharma, S.S. Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: old perspective with a new angle. Biochem. Biophys. Res. Commun., 2011, 408(1), 1-5.
    • (2011) Biochem. Biophys. Res. Commun. , vol.408 , Issue.1 , pp. 1-5
    • Negi, G.1    Kumar, A.2    Joshi, R.P.3    Sharma, S.S.4
  • 9
    • 0034038502 scopus 로고    scopus 로고
    • Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy
    • Stevens, M.J.; Obrosova, I.; Cao, X.; Van Huysen, C.; Greene, D.A. Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy. Diabetes, 2000, 49(6), 1006-1015.
    • (2000) Diabetes , vol.49 , Issue.6 , pp. 1006-1015
    • Stevens, M.J.1    Obrosova, I.2    Cao, X.3    Van Huysen, C.4    Greene, D.A.5
  • 10
    • 68749098097 scopus 로고    scopus 로고
    • Tocotrienol attenuates oxidative-nitrosative stress and inflammatory cascade in experimental model of diabetic neuropathy
    • Kuhad, A.; Chopra, K. Tocotrienol attenuates oxidative-nitrosative stress and inflammatory cascade in experimental model of diabetic neuropathy. Neuropharmacology, 2009, 57(4), 456-462.
    • (2009) Neuropharmacology , vol.57 , Issue.4 , pp. 456-462
    • Kuhad, A.1    Chopra, K.2
  • 11
    • 33745699476 scopus 로고    scopus 로고
    • Effects of U83836E on nerve functions, hyperalgesia and oxidative stress in experimental diabetic neuropathy
    • Sayyed, S.G.; Kumar, A.; Sharma, S.S. Effects of U83836E on nerve functions, hyperalgesia and oxidative stress in experimental diabetic neuropathy. Life Sci., 2006, 79(8), 777-783.
    • (2006) Life Sci. , vol.79 , Issue.8 , pp. 777-783
    • Sayyed, S.G.1    Kumar, A.2    Sharma, S.S.3
  • 12
    • 33745902804 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin attenuates thermal hyperalgesia and cold allodynia in STZinduced diabetic rats
    • Sharma, S.; Kulkarni, S.K.; Chopra, K. Resveratrol, a polyphenolic phytoalexin attenuates thermal hyperalgesia and cold allodynia in STZinduced diabetic rats. Indian. J. Exp. Biol., 2006, 44(7), 566-569.
    • (2006) Indian. J. Exp. Biol. , vol.44 , Issue.7 , pp. 566-569
    • Sharma, S.1    Kulkarni, S.K.2    Chopra, K.3
  • 13
    • 33846260752 scopus 로고    scopus 로고
    • Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain
    • Sharma, S.; Kulkarni, S.K.; Chopra, K. Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain. Fundam. Clin. Pharmacol., 2007, 21(1), 89-94.
    • (2007) Fundam. Clin. Pharmacol. , vol.21 , Issue.1 , pp. 89-94
    • Sharma, S.1    Kulkarni, S.K.2    Chopra, K.3
  • 14
    • 38849162084 scopus 로고    scopus 로고
    • The antioxidant response as a drug target in diabetic neuropathy
    • Vincent, A.M.; Edwards, J.L.; Sadidi, M.; Feldman, E.L. The antioxidant response as a drug target in diabetic neuropathy. Curr. Drug Targets, 2008, 9(1), 94-100.
    • (2008) Curr. Drug Targets , vol.9 , Issue.1 , pp. 94-100
    • Vincent, A.M.1    Edwards, J.L.2    Sadidi, M.3    Feldman, E.L.4
  • 15
    • 3142631792 scopus 로고    scopus 로고
    • New insights into the mechanisms of diabetic neuropathy
    • Vincent, A.M.; Feldman, E.L. New insights into the mechanisms of diabetic neuropathy. Rev. Endocr. Metab. Disord., 2004, 5(3), 227-236.
    • (2004) Rev. Endocr. Metab. Disord. , vol.5 , Issue.3 , pp. 227-236
    • Vincent, A.M.1    Feldman, E.L.2
  • 16
    • 11244318376 scopus 로고    scopus 로고
    • Resveratrol protects against peroxynitrite-induced thiol oxidation in blood platelets
    • Olas, B.; Nowak, P.; Wachowicz, B. Resveratrol protects against peroxynitrite-induced thiol oxidation in blood platelets. Cell Mol. Biol. Lett., 2004, 9(4A), 577-587.
    • (2004) Cell Mol. Biol. Lett. , vol.9 , Issue.4 A , pp. 577-587
    • Olas, B.1    Nowak, P.2    Wachowicz, B.3
  • 17
    • 17644445347 scopus 로고    scopus 로고
    • Biological activity of resveratrol
    • Olas, B.; Wachowicz, B. Biological activity of resveratrol. Postepy Hig. Med. Dosw., 2001, 55(1), 71-79.
    • (2001) Postepy Hig. Med. Dosw. , vol.55 , Issue.1 , pp. 71-79
    • Olas, B.1    Wachowicz, B.2
  • 19
    • 84862777886 scopus 로고    scopus 로고
    • Cardiovascular effects and molecular targets of resveratrol
    • Li, H.; Xia, N.; Forstermann, U. Cardiovascular effects and molecular targets of resveratrol. Nitric Oxide, 2012, 26(2), 102-110.
    • (2012) Nitric Oxide , vol.26 , Issue.2 , pp. 102-110
    • Li, H.1    Xia, N.2    Forstermann, U.3
  • 21
    • 0842304134 scopus 로고    scopus 로고
    • Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tertbutylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
    • Kraft, A.D.; Johnson, D.A.; Johnson, J.A. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tertbutylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. J. Neurosci., 2004, 24(5), 1101-1112.
    • (2004) J. Neurosci. , vol.24 , Issue.5 , pp. 1101-1112
    • Kraft, A.D.1    Johnson, D.A.2    Johnson, J.A.3
  • 22
    • 0037713341 scopus 로고    scopus 로고
    • Potential mechanism by which resveratrol, a red wine constituent, protects neurons
    • discussion 287-278
    • Zhuang, H.; Kim, Y.S.; Koehler, R.C.; Dore, S. Potential mechanism by which resveratrol, a red wine constituent, protects neurons. Ann. N. Y. Acad. Sci., 2003, 993, 276-286; discussion 287-278.
    • (2003) Ann. N. Y. Acad. Sci. , vol.993 , pp. 276-286
    • Zhuang, H.1    Kim, Y.S.2    Koehler, R.C.3    Dore, S.4
  • 23
    • 77953711040 scopus 로고    scopus 로고
    • Resveratrol protects against experimental stroke: Putative neuroprotective role of heme oxygenase 1
    • Sakata, Y.; Zhuang, H.; Kwansa, H.; Koehler, R.C.; Dore, S. Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1. Exp. Neurol., 2010, 224(1), 325-329.
    • (2010) Exp. Neurol. , vol.224 , Issue.1 , pp. 325-329
    • Sakata, Y.1    Zhuang, H.2    Kwansa, H.3    Koehler, R.C.4    Dore, S.5
  • 24
    • 77950189559 scopus 로고    scopus 로고
    • NF-kappaB inhibitory action of resveratrol: A probable mechanism of neuroprotection in experimental diabetic neuropathy
    • Kumar, A.; Sharma, S.S. NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy. Biochem. Biophys. Res. Commun., 2010, 394(2), 360-365.
    • (2010) Biochem. Biophys. Res. Commun. , vol.394 , Issue.2 , pp. 360-365
    • Kumar, A.1    Sharma, S.S.2
  • 25
    • 0034660659 scopus 로고    scopus 로고
    • Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: Potential role of reactive oxygen intermediates and lipid peroxidation
    • Manna, S.K.; Mukhopadhyay, A.; Aggarwal, B.B. Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation. J. Immunol., 2000, 164(12), 6509-6519.
    • (2000) J. Immunol. , vol.164 , Issue.12 , pp. 6509-6519
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 26
    • 77957923658 scopus 로고    scopus 로고
    • Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants
    • Olholm, J.; Paulsen, S.K.; Cullberg, K.B.; Richelsen, B.; Pedersen, S.B. Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants. Int. J. Obes. (Lond), 2010, 34(10), 1546-1553.
    • (2010) Int. J. Obes. (Lond) , vol.34 , Issue.10 , pp. 1546-1553
    • Olholm, J.1    Paulsen, S.K.2    Cullberg, K.B.3    Richelsen, B.4    Pedersen, S.B.5
  • 27
    • 0027283310 scopus 로고
    • Expression of c-fos and c-jun family genes after focal cerebral ischemia
    • An, G.; Lin, T.-N.; Liu, J.-S.; Xue, J.-J.; He, Y.-Y.; Hsu, C.Y. Expression of c-fos and c-jun family genes after focal cerebral ischemia. Ann. Neurol., 1993, 33(5), 457-464.
    • (1993) Ann. Neurol. , vol.33 , Issue.5 , pp. 457-464
    • An, G.1    Lin, T.-N.2    Liu, J.-S.3    Xue, J.-J.4    He, Y.-Y.5    Hsu, C.Y.6
  • 28
    • 79954445314 scopus 로고    scopus 로고
    • Attenuation of Neuronal Death by Peptide Inhibitors of AP-1 Activation in Acute and Delayed in Vitro Ischaemia (Oxygen/Glucose Deprivation) Models
    • Craig, A.; Meloni, B.; Watt, P.; Knuckey, N. Attenuation of Neuronal Death by Peptide Inhibitors of AP-1 Activation in Acute and Delayed In Vitro Ischaemia (Oxygen/Glucose Deprivation) Models. Intl. J. Peptide Res. Ther., 2011, 17(1), 1-6.
    • (2011) Intl. J. Peptide Res. Ther. , vol.17 , Issue.1 , pp. 1-6
    • Craig, A.1    Meloni, B.2    Watt, P.3    Knuckey, N.4
  • 29
    • 43149121596 scopus 로고    scopus 로고
    • Neurogenesis directed by Sirt1
    • Libert, S.; Cohen, D.; Guarente, L. Neurogenesis directed by Sirt1. Nat. Cell Biol., 2008, 10(4), 373-374.
    • (2008) Nat. Cell Biol. , vol.10 , Issue.4 , pp. 373-374
    • Libert, S.1    Cohen, D.2    Guarente, L.3
  • 30
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • Lin, S.J.; Defossez, P.A.; Guarente, L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science, 2000, 289(5487), 2126-2128.
    • (2000) Science , vol.289 , Issue.5487 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 31
    • 79959343572 scopus 로고    scopus 로고
    • The controversial links among calorie restriction, SIRT1, and resveratrol
    • Hu, Y.; Liu, J.; Wang, J.; Liu, Q. The controversial links among calorie restriction, SIRT1, and resveratrol. Free Radic. Biol. Med., 2011, 51(2), 250-256.
    • (2011) Free Radic. Biol. Med. , vol.51 , Issue.2 , pp. 250-256
    • Hu, Y.1    Liu, J.2    Wang, J.3    Liu, Q.4
  • 32
    • 84862306635 scopus 로고    scopus 로고
    • Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: Mechanistic insights
    • Yun, J.M.; Chien, A.; Jialal, I.; Devaraj, S. Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights. J. Nutr. Biochem., 2011, 23(7), 699-705.
    • (2011) J. Nutr. Biochem. , vol.23 , Issue.7 , pp. 699-705
    • Yun, J.M.1    Chien, A.2    Jialal, I.3    Devaraj, S.4
  • 33
    • 77955088481 scopus 로고    scopus 로고
    • Resveratrol as a therapeutic agent for neurodegenerative diseases
    • Sun, A.Y.; Wang, Q.; Simonyi, A.; Sun, G.Y. Resveratrol as a therapeutic agent for neurodegenerative diseases. Mol. Neurobiol., 2010, 41(2-3), 375-383.
    • (2010) Mol. Neurobiol. , vol.41 , Issue.2-3 , pp. 375-383
    • Sun, A.Y.1    Wang, Q.2    Simonyi, A.3    Sun, G.Y.4
  • 34
    • 34250860632 scopus 로고    scopus 로고
    • Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex i and potassium deprivation in cerebellar neurons
    • Alvira, D.; Yeste-Velasco, M.; Folch, J.; Verdaguer, E.; Canudas, A.M.; Pallas, M.; Camins, A. Comparative analysis of the effects of resveratrol in two apoptotic models: inhibition of complex I and potassium deprivation in cerebellar neurons. Neuroscience, 2007, 147(3), 746-756.
    • (2007) Neuroscience , vol.147 , Issue.3 , pp. 746-756
    • Alvira, D.1    Yeste-Velasco, M.2    Folch, J.3    Verdaguer, E.4    Canudas, A.M.5    Pallas, M.6    Camins, A.7
  • 35
    • 33747886389 scopus 로고    scopus 로고
    • Resveratrol-A boon for treating Alzheimer's disease? Brain Res
    • Anekonda, T.S. Resveratrol-a boon for treating Alzheimer's disease? Brain Res. Rev., 2006, 52(2), 316-326.
    • (2006) Rev. , vol.52 , Issue.2 , pp. 316-326
    • Anekonda, T.S.1
  • 36
    • 77954537252 scopus 로고    scopus 로고
    • Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: Neuroprotective effects of acetyl-l-carnitine and resveratrol
    • Binienda, Z.K.; Beaudoin, M.A.; Gough, B.; Ali, S.F.; Virmani, A. Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol. Neurosci. Lett., 2010, 480(2), 117-121.
    • (2010) Neurosci. Lett. , vol.480 , Issue.2 , pp. 117-121
    • Binienda, Z.K.1    Beaudoin, M.A.2    Gough, B.3    Ali, S.F.4    Virmani, A.5
  • 37
    • 60249091672 scopus 로고    scopus 로고
    • Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by resveratrol
    • Chang, Y.; Wang, S.J. Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by resveratrol. Neurochem. Int., 2009, 54(2), 135-141.
    • (2009) Neurochem. Int. , vol.54 , Issue.2 , pp. 135-141
    • Chang, Y.1    Wang, S.J.2
  • 38
    • 51549098145 scopus 로고    scopus 로고
    • Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity
    • Chao, J.; Yu, M.S.; Ho, Y.S.; Wang, M.; Chang, R.C. Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity. Free Radic. Biol. Med., 2008, 45(7), 1019-1026.
    • (2008) Free Radic. Biol. Med. , vol.45 , Issue.7 , pp. 1019-1026
    • Chao, J.1    Yu, M.S.2    Ho, Y.S.3    Wang, M.4    Chang, R.C.5
  • 40
    • 0037375768 scopus 로고    scopus 로고
    • Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells
    • Nicolini, G.; Rigolio, R.; Scuteri, A.; Miloso, M.; Saccomanno, D.; Cavaletti, G.; Tredici, G. Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurochem. Int., 2003, 42(5), 419-429.
    • (2003) Neurochem. Int. , vol.42 , Issue.5 , pp. 419-429
    • Nicolini, G.1    Rigolio, R.2    Scuteri, A.3    Miloso, M.4    Saccomanno, D.5    Cavaletti, G.6    Tredici, G.7
  • 41
    • 0037189154 scopus 로고    scopus 로고
    • Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats
    • Sinha, K.; Chaudhary, G.; Gupta, Y.K. Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats. Life Sci., 2002, 71(6), 655-665.
    • (2002) Life Sci. , vol.71 , Issue.6 , pp. 655-665
    • Sinha, K.1    Chaudhary, G.2    Gupta, Y.K.3
  • 42
    • 58849107536 scopus 로고    scopus 로고
    • Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms
    • Vincent, A.M.; Kato, K.; McLean, L.L.; Soules, M.E.; Feldman, E.L. Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms. Antioxid. Redox. Signal., 2009, 11(3), 425-438.
    • (2009) Antioxid. Redox. Signal. , vol.11 , Issue.3 , pp. 425-438
    • Vincent, A.M.1    Kato, K.2    McLean, L.L.3    Soules, M.E.4    Feldman, E.L.5
  • 43
    • 33747884526 scopus 로고    scopus 로고
    • Pharmacological evidence for the participation of NO-cyclic GMP-PKG-K+ channel pathway in the antiallodynic action of resveratrol
    • Bermudez-Ocana, D.Y.; Ambriz-Tututi, M.; Perez-Severiano, F.; Granados-Soto, V. Pharmacological evidence for the participation of NO-cyclic GMP-PKG-K+ channel pathway in the antiallodynic action of resveratrol. Pharmacol. Biochem. Behav., 2006, 84(3), 535-542.
    • (2006) Pharmacol. Biochem. Behav. , vol.84 , Issue.3 , pp. 535-542
    • Bermudez-Ocana, D.Y.1    Ambriz-Tututi, M.2    Perez-Severiano, F.3    Granados-Soto, V.4
  • 45
    • 54949153685 scopus 로고    scopus 로고
    • Antinociceptive effect of resveratrol in carrageenan-evoked hyperalgesia in rats: Prolonged effect related to COX-2 expression impairment
    • Pham-Marcou, T.A.; Beloeil, H.; Sun, X.; Gentili, M.; Yaici, D.; Benoit, G.; Benhamou, D.; Mazoit, J.X. Antinociceptive effect of resveratrol in carrageenan-evoked hyperalgesia in rats: prolonged effect related to COX-2 expression impairment. Pain, 2008, 140(2), 274-283.
    • (2008) Pain , vol.140 , Issue.2 , pp. 274-283
    • Pham-Marcou, T.A.1    Beloeil, H.2    Sun, X.3    Gentili, M.4    Yaici, D.5    Benoit, G.6    Benhamou, D.7    Mazoit, J.X.8
  • 46
    • 19444384138 scopus 로고    scopus 로고
    • Resveratrol inhibits Na+ currents in rat dorsal root ganglion neurons
    • Kim, H.I.; Kim, T.H.; Song, J.H. Resveratrol inhibits Na+ currents in rat dorsal root ganglion neurons. Brain Res., 2005, 1045(1-2), 134-141.
    • (2005) Brain Res. , vol.1045 , Issue.1-2 , pp. 134-141
    • Kim, H.I.1    Kim, T.H.2    Song, J.H.3
  • 47
    • 33847334999 scopus 로고    scopus 로고
    • Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy
    • Kumar, A.; Kaundal, R.K.; Iyer, S.; Sharma, S.S. Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy. Life Sci., 2007, 80(13), 1236-1244.
    • (2007) Life Sci. , vol.80 , Issue.13 , pp. 1236-1244
    • Kumar, A.1    Kaundal, R.K.2    Iyer, S.3    Sharma, S.S.4
  • 48
    • 67650180132 scopus 로고    scopus 로고
    • Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: Focus on functional, sensorimotor and biochemical changes
    • Sharma, S.S.; Kumar, A.; Arora, M.; Kaundal, R.K. Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: focus on functional, sensorimotor and biochemical changes. Free Radic. Res., 2009, 43(4), 400-408.
    • (2009) Free Radic. Res. , vol.43 , Issue.4 , pp. 400-408
    • Sharma, S.S.1    Kumar, A.2    Arora, M.3    Kaundal, R.K.4
  • 49
    • 33947579407 scopus 로고    scopus 로고
    • Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: Participation of nitric oxide and TNF-alpha
    • Sharma, S.; Chopra, K.; Kulkarni, S.K. Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF-alpha. Phytother. Res., 2007, 21(3), 278-283.
    • (2007) Phytother. Res. , vol.21 , Issue.3 , pp. 278-283
    • Sharma, S.1    Chopra, K.2    Kulkarni, S.K.3
  • 51
    • 0032520905 scopus 로고    scopus 로고
    • Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro
    • Rochelle, L.G.; Fischer, B.M.; Adler, K.B. Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro. Free Radic. Biol. Med., 1998, 24(5), 863-868.
    • (1998) Free Radic. Biol. Med. , vol.24 , Issue.5 , pp. 863-868
    • Rochelle, L.G.1    Fischer, B.M.2    Adler, K.B.3
  • 52
    • 0038729614 scopus 로고    scopus 로고
    • Effects of resveratrol on secondary damages after acute spinal cord injury in rats
    • Yang, Y.B.; Piao, Y.J. Effects of resveratrol on secondary damages after acute spinal cord injury in rats. Acta Pharmacol. Sin., 2003, 24(7), 703-710.
    • (2003) Acta Pharmacol. Sin. , vol.24 , Issue.7 , pp. 703-710
    • Yang, Y.B.1    Piao, Y.J.2
  • 53
    • 0027265033 scopus 로고
    • Reduction of cyclic AMP in the sciatic nerve of rats made diabetic with streptozotocin and the mechanism involved
    • Shindo, H.; Tawata, M.; Onaya, T. Reduction of cyclic AMP in the sciatic nerve of rats made diabetic with streptozotocin and the mechanism involved. J. Endocrinol., 1993, 136(3), 431-438.
    • (1993) J. Endocrinol. , vol.136 , Issue.3 , pp. 431-438
    • Shindo, H.1    Tawata, M.2    Onaya, T.3
  • 54
    • 0038309561 scopus 로고    scopus 로고
    • Resveratrol activates adenylylcyclase in human breast cancer cells: A novel, estrogen receptorindependent cytostatic mechanism
    • El-Mowafy, A.M.; Alkhalaf, M. Resveratrol activates adenylylcyclase in human breast cancer cells: a novel, estrogen receptorindependent cytostatic mechanism. Carcinogenesis, 2003, 24(5), 869-873.
    • (2003) Carcinogenesis , vol.24 , Issue.5 , pp. 869-873
    • El-Mowafy, A.M.1    Alkhalaf, M.2
  • 55
    • 0036303144 scopus 로고    scopus 로고
    • Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats
    • Freshwater, J.D.; Svensson, C.I.; Malmberg, A.B.; Calcutt, N.A. Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes, 2002, 51(7), 2249-2255.
    • (2002) Diabetes , vol.51 , Issue.7 , pp. 2249-2255
    • Freshwater, J.D.1    Svensson, C.I.2    Malmberg, A.B.3    Calcutt, N.A.4
  • 56
    • 84872533007 scopus 로고    scopus 로고
    • In vitro hyperglycemia enhances sodium currents in dorsal root ganglion neurons: An effect attenuated by carbamazepine
    • Singh, J.N.; Jain, G.; Sharma, S.S. In vitro hyperglycemia enhances sodium currents in dorsal root ganglion neurons: An effect attenuated by carbamazepine. Neuroscience, 2013, 232C, 64-73.
    • (2013) Neuroscience , vol.232 C , pp. 64-73
    • Singh, J.N.1    Jain, G.2    Sharma, S.S.3
  • 57
    • 0842332392 scopus 로고    scopus 로고
    • Neuroprotective effect of combination of poly (ADP-ribose) polymerase inhibitor and antioxidant in middle cerebral artery occlusion induced focal ischemia in rats
    • Gupta, S.; Kaul, C.L.; Sharma, S.S. Neuroprotective effect of combination of poly (ADP-ribose) polymerase inhibitor and antioxidant in middle cerebral artery occlusion induced focal ischemia in rats. Neurol. Res., 2004, 26(1), 103-107.
    • (2004) Neurol. Res. , vol.26 , Issue.1 , pp. 103-107
    • Gupta, S.1    Kaul, C.L.2    Sharma, S.S.3
  • 60
    • 77249089947 scopus 로고    scopus 로고
    • Resveratrol (trans-3, 5, 4'-trihydroxystilbene) induces SIRT1 and down-regulates NF-{kappa}B activation to abrogate DSS-induced colitis
    • Singh, U.P.; Singh, N.; Singh, B.; Hofseth, L.J.; Price, B.L.; Nagarkatti, M.; Nagarkatti, P. Resveratrol (trans-3, 5, 4'-trihydroxystilbene) induces SIRT1 and down-regulates NF-{kappa}B activation to abrogate DSS-induced colitis. J. Pharmacol. Exp. Ther., 2009, 332(3), 829-839.
    • (2009) J. Pharmacol. Exp. Ther. , vol.332 , Issue.3 , pp. 829-839
    • Singh, U.P.1    Singh, N.2    Singh, B.3    Hofseth, L.J.4    Price, B.L.5    Nagarkatti, M.6    Nagarkatti, P.7
  • 61
    • 79251601931 scopus 로고    scopus 로고
    • Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury
    • Liu, C.; Shi, Z.; Fan, L.; Zhang, C.; Wang, K.; Wang, B. Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury. Brain Res., 2012, 1374, 100-109.
    • (2012) Brain Res. , vol.1374 , pp. 100-109
    • Liu, C.1    Shi, Z.2    Fan, L.3    Zhang, C.4    Wang, K.5    Wang, B.6
  • 62
    • 82155197554 scopus 로고    scopus 로고
    • Nrf2 and NF-kappaB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes
    • Negi, G.; Kumar, A.; Sharma, S.S. Nrf2 and NF-kappaB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes. Curr. Neurovasc. Res., 2011, 8(4), 294-304.
    • (2011) Curr. Neurovasc. Res. , vol.8 , Issue.4 , pp. 294-304
    • Negi, G.1    Kumar, A.2    Sharma, S.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.