메뉴 건너뛰기




Volumn 1622, Issue , 2015, Pages 217-229

Activation of transcription factors STAT1 and STAT5 in the mouse median eminence after systemic ciliary neurotrophic factor administration

Author keywords

Cytokines; Energy balance; Hypothalamus; Obesity; Signal transducers and activator of transcription; Tanycytes

Indexed keywords

RECOMBINANT CILIARY NEUROTROPHIC FACTOR; STAT1 PROTEIN; STAT5 PROTEIN; TYROSINE; ANTIOBESITY AGENT; CENTRAL NERVOUS SYSTEM AGENTS; CILIARY NEUROTROPHIC FACTOR; PROTEIN C FOS; STAT1 PROTEIN, MOUSE;

EID: 84940935364     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.06.028     Document Type: Article
Times cited : (13)

References (50)
  • 1
    • 2442646665 scopus 로고    scopus 로고
    • A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group
    • ACTS A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group Neurology 46 1996 1244 1249
    • (1996) Neurology , vol.46 , pp. 1244-1249
  • 2
    • 0018764763 scopus 로고
    • Cholinergic neuronotrophic factors: Intraocular distribution of trophic activity for ciliary neurons
    • R. Adler, K.B. Landa, M. Manthorpe, and S. Varon Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons Science 204 1979 1434 1436 10.1126/science.451576
    • (1979) Science , vol.204 , pp. 1434-1436
    • Adler, R.1    Landa, K.B.2    Manthorpe, M.3    Varon, S.4
  • 3
    • 79955633333 scopus 로고    scopus 로고
    • Overcoming insulin resistance with ciliary neurotrophic factor
    • T.L. Allen, V.B. Matthews, and M.A. Febbraio Overcoming insulin resistance with ciliary neurotrophic factor Handb. Exp. Pharmacol. 203 2011 179 199 10.1007/978-3-642-17214-4-9
    • (2011) Handb. Exp. Pharmacol. , vol.203 , pp. 179-199
    • Allen, T.L.1    Matthews, V.B.2    Febbraio, M.A.3
  • 4
    • 52449093433 scopus 로고    scopus 로고
    • Gene expression in arcuate nucleus-median eminence of rats treated with leptin or ciliary neurotrophic factor
    • S. Ambati, J. Duan, E. Duff, Y.-H. Choi, D.L. Hartzell, M.A. Della-Fera, and C.A. Baile Gene expression in arcuate nucleus-median eminence of rats treated with leptin or ciliary neurotrophic factor BioFactors 31 2007 133 144
    • (2007) BioFactors , vol.31 , pp. 133-144
    • Ambati, S.1    Duan, J.2    Duff, E.3    Choi, Y.-H.4    Hartzell, D.L.5    Della-Fera, M.A.6    Baile, C.A.7
  • 5
    • 0038054034 scopus 로고    scopus 로고
    • Activation of the hypothalamic arcuate nucleus predicts the anorectic actions of ciliary neurotrophic factor and leptin in intact and gold thioglucose-lesioned mice
    • K.D. Anderson, P.D. Lambert, T.L. Corcoran, J.D. Murray, K.E. Thabet, G.D. Yancopoulos, and S.J. Wiegand Activation of the hypothalamic arcuate nucleus predicts the anorectic actions of ciliary neurotrophic factor and leptin in intact and gold thioglucose-lesioned mice J. Neuroendocrinol. 15 2003 649 660 10.1046/j.1365-2826.2003.01043.x
    • (2003) J. Neuroendocrinol. , vol.15 , pp. 649-660
    • Anderson, K.D.1    Lambert, P.D.2    Corcoran, T.L.3    Murray, J.D.4    Thabet, K.E.5    Yancopoulos, G.D.6    Wiegand, S.J.7
  • 7
    • 84873162774 scopus 로고    scopus 로고
    • Hypothalamic tanycytes: Potential roles in the control of feeding and energy balance
    • M. Bolborea, and N. Dale Hypothalamic tanycytes: potential roles in the control of feeding and energy balance Trend Neurosci. 36 2013 91 100 10.1016/j.tins.2012.12.008
    • (2013) Trend Neurosci. , vol.36 , pp. 91-100
    • Bolborea, M.1    Dale, N.2
  • 10
    • 0032532614 scopus 로고    scopus 로고
    • Oligodendroglial survival factors, PDGF-AA and CNTF, activate similar JAK/STAT signaling pathways
    • P. Dell'Albani, M.A. Kahn, R. Cole, D.F. Condorelli, A.M. Giuffrida-Stella, and J. de Vellis Oligodendroglial survival factors, PDGF-AA and CNTF, activate similar JAK/STAT signaling pathways J. Neurosci. Res. 54 1998 191 205 http://dx.doi.org/10.1002/(SICI)1097-4547(19981015)54:2<191::AID-JNR7>3.0.CO;2-9
    • (1998) J. Neurosci. Res. , vol.54 , pp. 191-205
    • Dell'Albani, P.1    Kahn, M.A.2    Cole, R.3    Condorelli, D.F.4    Giuffrida-Stella, A.M.5    De Vellis, J.6
  • 12
    • 34147159710 scopus 로고    scopus 로고
    • Gp130 receptor ligands as potential therapeutic targets for obesity
    • M.A. Febbraio Gp130 receptor ligands as potential therapeutic targets for obesity J. Clin. Investig. 117 2007 841 849 10.1172/JCI30453
    • (2007) J. Clin. Investig. , vol.117 , pp. 841-849
    • Febbraio, M.A.1
  • 15
    • 35648968069 scopus 로고    scopus 로고
    • The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms
    • Y. Gong, R. Ishida-Takahashi, E.C. Villanueva, D.C. Fingar, H. Munzberg, and M.G. Myers Jr. The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms J. Biol. Chem. 282 2007 31019 31027 10.1074/jbc.M702838200
    • (2007) J. Biol. Chem. , vol.282 , pp. 31019-31027
    • Gong, Y.1    Ishida-Takahashi, R.2    Villanueva, E.C.3    Fingar, D.C.4    Munzberg, H.5    Myers, M.G.6
  • 17
    • 14044257944 scopus 로고    scopus 로고
    • Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function
    • B. Holtmann, S. Wiese, M. Samsam, K. Grohmann, D. Pennica, R. Martini, and M. Sendtner Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function J. Neurosci. 25 2005 1778 1787 10.1523/JNEUROSCI.4249-04.2005
    • (2005) J. Neurosci. , vol.25 , pp. 1778-1787
    • Holtmann, B.1    Wiese, S.2    Samsam, M.3    Grohmann, K.4    Pennica, D.5    Martini, R.6    Sendtner, M.7
  • 18
    • 0035313069 scopus 로고    scopus 로고
    • Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation
    • T. Hubschle, E. Thom, A. Watson, J. Roth, S. Klaus, and W. Meyerhof Leptin-induced nuclear translocation of STAT3 immunoreactivity in hypothalamic nuclei involved in body weight regulation J. Neurosci. 21 2001 2413 2424
    • (2001) J. Neurosci. , vol.21 , pp. 2413-2424
    • Hubschle, T.1    Thom, E.2    Watson, A.3    Roth, J.4    Klaus, S.5    Meyerhof, W.6
  • 19
    • 33746075210 scopus 로고    scopus 로고
    • Gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor
    • R. Janoschek, L. Plum, L. Koch, H. Munzberg, S. Diano, M. Shanabrough, W. Muller, T.L. Horvath, and J.C. Bruning gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor Proc. Natl. Acad. Sci. USA 103 2006 10707 10712 10.1073/pnas.0600425103
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10707-10712
    • Janoschek, R.1    Plum, L.2    Koch, L.3    Munzberg, H.4    Diano, S.5    Shanabrough, M.6    Muller, W.7    Horvath, T.L.8    Bruning, J.C.9
  • 21
    • 27344441682 scopus 로고    scopus 로고
    • Neurogenesis in the hypothalamus of adult mice: Potential role in energy balance
    • M.V. Kokoeva, H. Yin, and J.S. Flier Neurogenesis in the hypothalamus of adult mice: potential role in energy balance Science 310 2005 679 683 10.1126/science.1115360
    • (2005) Science , vol.310 , pp. 679-683
    • Kokoeva, M.V.1    Yin, H.2    Flier, J.S.3
  • 22
    • 84863204371 scopus 로고    scopus 로고
    • Suppression of leptin-induced hypothalamic JAK/STAT signalling and feeding response during pregnancy in the mouse
    • S.R. Ladyman, D.M. Fieldwick, and D.R. Grattan Suppression of leptin-induced hypothalamic JAK/STAT signalling and feeding response during pregnancy in the mouse Reproduction 144 2012 83 90 10.1530/REP-12-0112
    • (2012) Reproduction , vol.144 , pp. 83-90
    • Ladyman, S.R.1    Fieldwick, D.M.2    Grattan, D.R.3
  • 27
    • 0035933555 scopus 로고    scopus 로고
    • Nuclear translocation of STAT5 and increased expression of Fos related antigens (FRAs) in hypothalamic dopaminergic neurons after prolactin administration
    • A. Lerant, B. Kanyicska, and M.E. Freeman Nuclear translocation of STAT5 and increased expression of Fos related antigens (FRAs) in hypothalamic dopaminergic neurons after prolactin administration Brain Res. 904 2001 259 269 10.1016/S0006-8993(01)02470-2
    • (2001) Brain Res. , vol.904 , pp. 259-269
    • Lerant, A.1    Kanyicska, B.2    Freeman, M.E.3
  • 28
    • 79959428713 scopus 로고    scopus 로고
    • Metabolic sensing and the brain: Who, what, where, and how?
    • B.E. Levin, C. Magnan, A. Dunn-Meynell, and C. Le Foll Metabolic sensing and the brain: who, what, where, and how? Endocrinology 152 2011 2552 2557 10.1210/en.2011-0194
    • (2011) Endocrinology , vol.152 , pp. 2552-2557
    • Levin, B.E.1    Magnan, C.2    Dunn-Meynell, A.3    Le Foll, C.4
  • 29
    • 0031768207 scopus 로고    scopus 로고
    • Leptin signaling in the hypothalamus of normal rats in vivo
    • K.C. McCowen, J.C. Chow, and R.J. Smith Leptin signaling in the hypothalamus of normal rats in vivo Endocrinology 139 1998 4442 4447 10.1210/endo.139.11.6301
    • (1998) Endocrinology , vol.139 , pp. 4442-4447
    • McCowen, K.C.1    Chow, J.C.2    Smith, R.J.3
  • 31
    • 84901006228 scopus 로고    scopus 로고
    • Neurobiology of food intake in health and disease
    • J.G. Morton, T.H. Meek, and M.W. Schwartz Neurobiology of food intake in health and disease Nat. Rev. Neurosci. 15 2014 367 378 10.1038/nrn3745
    • (2014) Nat. Rev. Neurosci. , vol.15 , pp. 367-378
    • Morton, J.G.1    Meek, T.H.2    Schwartz, M.W.3
  • 32
    • 77649274000 scopus 로고    scopus 로고
    • Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain
    • A. Mullier, S.G. Bouret, V. Prevot, and B. Dehouck Differential distribution of tight junction proteins suggests a role for tanycytes in blood-hypothalamus barrier regulation in the adult mouse brain J. Comp. Neurol. 518 2010 943 962 10.1002/cne.22273
    • (2010) J. Comp. Neurol. , vol.518 , pp. 943-962
    • Mullier, A.1    Bouret, S.G.2    Prevot, V.3    Dehouck, B.4
  • 33
    • 34247102713 scopus 로고    scopus 로고
    • Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration
    • J. Mutze, J. Roth, R. Gerstberger, and T Hubschle Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration Neurosci. Lett. 417 2007 286 291 10.1016/j.neulet.2007.02.074
    • (2007) Neurosci. Lett. , vol.417 , pp. 286-291
    • Mutze, J.1    Roth, J.2    Gerstberger, R.3    Hubschle, T.4
  • 36
    • 0029986152 scopus 로고    scopus 로고
    • STAT proteins are activated by ciliary neurotrophic factor in cells of central nervous system origin
    • P. Rajan, A.J. Symes, and J.S. Fink STAT proteins are activated by ciliary neurotrophic factor in cells of central nervous system origin J. Neurosci. Res. 43 1996 403 411
    • (1996) J. Neurosci. Res. , vol.43 , pp. 403-411
    • Rajan, P.1    Symes, A.J.2    Fink, J.S.3
  • 37
    • 0034984796 scopus 로고    scopus 로고
    • Leptin and tumor necrosis factor-α induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo
    • N.M. Rizk, D. Stammsen, G. Preibisch, and J. Eckel Leptin and tumor necrosis factor-α induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo Endocrinology 142 2001 3027 3032 10.1210/endo.142.7.8225
    • (2001) Endocrinology , vol.142 , pp. 3027-3032
    • Rizk, N.M.1    Stammsen, D.2    Preibisch, G.3    Eckel, J.4
  • 39
    • 77649276018 scopus 로고    scopus 로고
    • The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: The former opens to the portal blood and the latter to the cerebrospinal fluid
    • E.M. Rodrìguez, J.L. Blàzquez, and M. Guerra The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: the former opens to the portal blood and the latter to the cerebrospinal fluid Peptides 31 2010 757 776 10.1016/j.peptides.2010.01.003
    • (2010) Peptides , vol.31 , pp. 757-776
    • Rodrìguez, E.M.1    Blàzquez, J.L.2    Guerra, M.3
  • 41
    • 84893137029 scopus 로고    scopus 로고
    • Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance
    • M. Schneeberger, R. Gomis, and M. Claret Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance J. Endocrinol. 220 2014 T25 T46 10.1530/JOE-13-0398
    • (2014) J. Endocrinol. , vol.220 , pp. T25-T46
    • Schneeberger, M.1    Gomis, R.2    Claret, M.3
  • 43
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    • M. Sendtner, H. Schmalbruch, K.A. Stockli, P. Carroll, G.W. Kreutzberg, and H. Thoenen Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy Nature 358 1992 502 504 10.1038/358502a0
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stockli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 45
    • 84860440327 scopus 로고    scopus 로고
    • Constitutive expression of ciliary neurotrophic factor in mouse hypothalamus
    • I. Severi, M.R. Carradori, T. Lorenzi, A. Amici, S. Cinti, and A. Giordano Constitutive expression of ciliary neurotrophic factor in mouse hypothalamus J. Anat. 220 2012 622 631 10.1111/j.1469-7580.2012.01498.x
    • (2012) J. Anat. , vol.220 , pp. 622-631
    • Severi, I.1    Carradori, M.R.2    Lorenzi, T.3    Amici, A.4    Cinti, S.5    Giordano, A.6
  • 46
    • 84898043483 scopus 로고    scopus 로고
    • Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus
    • I. Severi, J. Perugini, E. Mondini, A. Smorlesi, A. Frontini, S Cinti, and A. Giordano Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus Front. Neurosci. 7 2013 263 10.3389/fnins.2013.00263
    • (2013) Front. Neurosci. , vol.7 , pp. 263
    • Severi, I.1    Perugini, J.2    Mondini, E.3    Smorlesi, A.4    Frontini, A.5    Cinti, S.6    Giordano, A.7
  • 48
    • 77949735378 scopus 로고    scopus 로고
    • Assembly and activation of neurotrophic factor receptor complexes
    • A. Simi, and C.F. Ibanez Assembly and activation of neurotrophic factor receptor complexes Dev. Neurobiol. 70 2010 523 531 10.1002/dneu.20773
    • (2010) Dev. Neurobiol. , vol.70 , pp. 523-531
    • Simi, A.1    Ibanez, C.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.