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Volumn 21, Issue 9, 2015, Pages 711-722

WNT3 and membrane-associated β-catenin regulate trophectoderm lineage differentiation in human blastocysts

Author keywords

EOMES; Human embryo; Trophoblast; WNT; catenin

Indexed keywords

1 AZAKENPAULLONE; BETA CATENIN; CARDAMONIN; CHEMICAL COMPOUND; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; LEVO AZAKENPAULLONE; OCTAMER TRANSCRIPTION FACTOR 4; RNA; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; WNT3 PROTEIN; CTNNB1 PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MESSENGER RNA; PROTEIN KINASE INHIBITOR; WNT3 PROTEIN, HUMAN;

EID: 84940878951     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gav036     Document Type: Article
Times cited : (38)

References (92)
  • 1
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H, Bauer A, Stappert J, Kispert A, Kemler R. Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J 1997;16:3797-3804.
    • (1997) EMBO J , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 4
    • 84860299776 scopus 로고    scopus 로고
    • The Wnt signaling pathways and cell adhesion
    • Amin N, Vincan E. The Wnt signaling pathways and cell adhesion. Front Biosci (Landmark Ed) 2012;17:784-804.
    • (2012) Front Biosci (Landmark Ed) , vol.17 , pp. 784-804
    • Amin, N.1    Vincan, E.2
  • 6
    • 80053087455 scopus 로고    scopus 로고
    • Howdo they doWntthey do?: regulation of transcription by the Wnt/b-catenin pathway
    • Archbold HC, Yang YX, Chen L, Cadigan KM. Howdo they doWntthey do?: regulation of transcription by the Wnt/b-catenin pathway. Acta Physiol (Oxf) 2012;204:74-109.
    • (2012) Acta Physiol (Oxf) , vol.204 , pp. 74-109
    • Archbold, H.C.1    Yang, Y.X.2    Chen, L.3    Cadigan, K.M.4
  • 7
    • 84883452530 scopus 로고    scopus 로고
    • Wnt signalling in mouse gastrulation and anterior development: new players in the pathway and signal output
    • Arkell RM, Fossat N, Tam PP. Wnt signalling in mouse gastrulation and anterior development: new players in the pathway and signal output. Curr Opin Genet Dev 2013;23:454-460.
    • (2013) Curr Opin Genet Dev , vol.23 , pp. 454-460
    • Arkell, R.M.1    Fossat, N.2    Tam, P.P.3
  • 9
    • 84923265392 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases
    • Beurel E, Grieco SF, Jope RS. Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases. Pharmacol Ther 2015;148C:114-131.
    • (2015) Pharmacol Ther , vol.148 C , pp. 114-131
    • Beurel, E.1    Grieco, S.F.2    Jope, R.S.3
  • 10
    • 84867028809 scopus 로고    scopus 로고
    • Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors
    • Blauwkamp TA, Nigam S, Ardehali R, Weissman IL, Nusse R. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nat Commun 2012;3:1070.
    • (2012) Nat Commun , vol.3 , pp. 1070
    • Blauwkamp, T.A.1    Nigam, S.2    Ardehali, R.3    Weissman, I.L.4    Nusse, R.5
  • 11
    • 79958090845 scopus 로고    scopus 로고
    • A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3
    • Bone HK, Nelson AS, Goldring CE, Tosh D,Welham MJ. A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J Cell Sci 2011; 124:1992-2000.
    • (2011) J Cell Sci , vol.124 , pp. 1992-2000
    • Bone, H.K.1    Nelson, A.S.2    Goldring, C.E.3    Tosh, D.4    Welham, M.J.5
  • 12
    • 0026878253 scopus 로고
    • Structure and interactions of desmosomal and other cadherins
    • Buxton RS, Magee AI. Structure and interactions of desmosomal and other cadherins. Semin Cell Biol 1992;3:157-167.
    • (1992) Semin Cell Biol , vol.3 , pp. 157-167
    • Buxton, R.S.1    Magee, A.I.2
  • 13
    • 24944462075 scopus 로고    scopus 로고
    • DAZL expression in human oocytes, preimplantation embryos and embryonic stem cells
    • Cauffman G, Van de Velde H, Liebaers I, Van Steirteghem A. DAZL expression in human oocytes, preimplantation embryos and embryonic stem cells. Mol Hum Reprod 2005;11:405-411.
    • (2005) Mol Hum Reprod , vol.11 , pp. 405-411
    • Cauffman, G.1    Van de Velde, H.2    Liebaers, I.3    Van Steirteghem, A.4
  • 14
    • 33846000940 scopus 로고    scopus 로고
    • POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos
    • Cauffman G, Liebaers I, Van Steirteghem A, Van de Velde H. POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos. Stem Cells 2006;24:2685-2691.
    • (2006) Stem Cells , vol.24 , pp. 2685-2691
    • Cauffman, G.1    Liebaers, I.2    Van Steirteghem, A.3    Van de Velde, H.4
  • 15
    • 57749198043 scopus 로고    scopus 로고
    • Markersthat define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos
    • Cauffman G,DeRyckeM, SermonK, Liebaers I, VandeVelde H. Markersthat define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos. Hum Reprod 2009;24:63-70.
    • (2009) Hum Reprod , vol.24 , pp. 63-70
    • Cauffman, G.1    DeRycke, M.2    Sermon, K.3    Liebaers, I.4    VandeVelde, H.5
  • 16
    • 58949095815 scopus 로고    scopus 로고
    • Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines
    • Chen AE, Egli D, Niakan K, Deng J, Akutsu H, Yamaki M, Cowan C, Fitz-Gerald C, Zhang K, Melton DA et al. Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. Cell Stem Cell 2009; 4:103-106.
    • (2009) Cell Stem Cell , vol.4 , pp. 103-106
    • Chen, A.E.1    Egli, D.2    Niakan, K.3    Deng, J.4    Akutsu, H.5    Yamaki, M.6    Cowan, C.7    Fitz-Gerald, C.8    Zhang, K.9    Melton, D.A.10
  • 19
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling and disease
    • Clevers H, Nusse R. Wnt/b-catenin signaling and disease. Cell 2012; 149:1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 25
    • 28444438841 scopus 로고    scopus 로고
    • Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells
    • Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 2005;23:1489-1501.
    • (2005) Stem Cells , vol.23 , pp. 1489-1501
    • Dravid, G.1    Ye, Z.2    Hammond, H.3    Chen, G.4    Pyle, A.5    Donovan, P.6    Yu, X.7    Cheng, L.8
  • 26
    • 79957533987 scopus 로고    scopus 로고
    • The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting
    • Embryology ASiRMaESIGo. The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. Hum Reprod 2011; 26:1270-1283.
    • (2011) Hum Reprod , vol.26 , pp. 1270-1283
  • 27
    • 0037031887 scopus 로고    scopus 로고
    • Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter
    • Filali M, Cheng N, Abbott D, Leontiev V, Engelhardt JF. Wnt-3A/β-catenin signaling induces transcription from the LEF-1 promoter. J Biol Chem 2002;277:33398-33410.
    • (2002) J Biol Chem , vol.277 , pp. 33398-33410
    • Filali, M.1    Cheng, N.2    Abbott, D.3    Leontiev, V.4    Engelhardt, J.F.5
  • 28
    • 73249136946 scopus 로고    scopus 로고
    • Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation
    • Fu J, Jiang M, Mirando AJ, Yu HM, HsuW. Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation. Proc Natl Acad Sci U S A 2009;106:18598-18603.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18598-18603
    • Fu, J.1    Jiang, M.2    Mirando, A.J.3    Yu, H.M.4    Hsu, W.5
  • 29
    • 29144470151 scopus 로고    scopus 로고
    • Defining the roles of beta-catenin and plakoglobin in cell-cell adhesion: isolation of beta-catenin/plakoglobin-deficient F9 cells
    • Fukunaga Y, Liu H, Shimizu M, Komiya S, Kawasuji M, Nagafuchi A. Defining the roles of beta-catenin and plakoglobin in cell-cell adhesion: isolation of beta-catenin/plakoglobin-deficient F9 cells. Cell Struct Funct 2005; 30:25-34.
    • (2005) Cell Struct Funct , vol.30 , pp. 25-34
    • Fukunaga, Y.1    Liu, H.2    Shimizu, M.3    Komiya, S.4    Kawasuji, M.5    Nagafuchi, A.6
  • 31
    • 57449090247 scopus 로고    scopus 로고
    • Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity
    • Greber B, Lehrach H, Adjaye J. Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity. Stem Cells Dev 2008; 17:1065-1077.
    • (2008) Stem Cells Dev , vol.17 , pp. 1065-1077
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 34
    • 30544450976 scopus 로고    scopus 로고
    • WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells
    • Hao J, Li TG, Qi X, Zhao DF, Zhao GQ. WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells. Dev Biol 2006;290:81-91.
    • (2006) Dev Biol , vol.290 , pp. 81-91
    • Hao, J.1    Li, T.G.2    Qi, X.3    Zhao, D.F.4    Zhao, G.Q.5
  • 35
    • 49249088702 scopus 로고    scopus 로고
    • Lymphoid enhancer factor 1-mediated Wnt signaling promotes the initiation of trophoblast lineage differentiation in mouse embryonic stem cells
    • He S, Pant D, Schiffmacher A, Meece A, Keefer CL. Lymphoid enhancer factor 1-mediated Wnt signaling promotes the initiation of trophoblast lineage differentiation in mouse embryonic stem cells. Stem Cells 2008; 26:842-849.
    • (2008) Stem Cells , vol.26 , pp. 842-849
    • He, S.1    Pant, D.2    Schiffmacher, A.3    Meece, A.4    Keefer, C.L.5
  • 36
    • 77951956038 scopus 로고    scopus 로고
    • A comparative genome analysis of gene expression reveals different regulatory mechanisms between mouse and human embryo pre-implantation development
    • He K, Zhao H, Wang Q, Pan Y. A comparative genome analysis of gene expression reveals different regulatory mechanisms between mouse and human embryo pre-implantation development. Reprod Biol Endocrinol 2010;8:41.
    • (2010) Reprod Biol Endocrinol , vol.8 , pp. 41
    • He, K.1    Zhao, H.2    Wang, Q.3    Pan, Y.4
  • 37
    • 84864395840 scopus 로고    scopus 로고
    • WNT secretion and signalling in human disease
    • Herr P, Hausmann G, Basler K. WNT secretion and signalling in human disease. Trends Mol Med 2012;18:483-493.
    • (2012) Trends Mol Med , vol.18 , pp. 483-493
    • Herr, P.1    Hausmann, G.2    Basler, K.3
  • 40
    • 16244400050 scopus 로고    scopus 로고
    • TGFbeta/activin/ nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/ nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 2005;132:1273-1282.
    • (2005) Development , vol.132 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3    Hemmati-Brivanlou, A.4
  • 41
    • 84929460999 scopus 로고    scopus 로고
    • b-Catenin and NF-kB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer
    • Jia D, YangW, Li L, Liu H, Tan Y, Ooi S, Chi L, Filion LG, Figeys D,Wang L. b-Catenin and NF-kB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ 2014;22:298-310.
    • (2014) Cell Death Differ , vol.22 , pp. 298-310
    • Jia, D.1    Yang, W.2    Li, L.3    Liu, H.4    Tan, Y.5    Ooi, S.6    Chi, L.7    Filion, L.G.8    Figeys, D.9    Wang, L.10
  • 42
    • 0027185632 scopus 로고
    • From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion
    • Kemler R. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 1993;9:317-321.
    • (1993) Trends Genet , vol.9 , pp. 317-321
    • Kemler, R.1
  • 43
    • 84892178502 scopus 로고    scopus 로고
    • Modulation of b-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal
    • Kim H,WuJ, Ye S, Tai CI, Zhou X, Yan H, Li P, PeraM, Ying QL. Modulation of b-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal. Nat Commun 2013;4:2403.
    • (2013) Nat Commun , vol.4 , pp. 2403
    • Kim, H.1    Wu, J.2    Ye, S.3    Tai, C.I.4    Zhou, X.5    Yan, H.6    Li, P.7    Pera, M.8    Ying, Q.L.9
  • 44
    • 0033516261 scopus 로고    scopus 로고
    • A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain
    • Kimura N, Nakashima K, Ueno M, Kiyama H, Taga T. A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain. Brain Res Dev Brain Res 1999;115:183-193.
    • (1999) Brain Res Dev Brain Res , vol.115 , pp. 183-193
    • Kimura, N.1    Nakashima, K.2    Ueno, M.3    Kiyama, H.4    Taga, T.5
  • 45
    • 3242885448 scopus 로고    scopus 로고
    • Elevated progesterone at initiation of stimulation is associated with a lower ongoing pregnancy rate after IVF using GnRH antagonists
    • Kolibianakis EM, Zikopoulos K, Smitz J, Camus M, Tournaye H, Van Steirteghem AC, Devroey P. Elevated progesterone at initiation of stimulation is associated with a lower ongoing pregnancy rate after IVF using GnRH antagonists. Hum Reprod 2004;19:1525-1529.
    • (2004) Hum Reprod , vol.19 , pp. 1525-1529
    • Kolibianakis, E.M.1    Zikopoulos, K.2    Smitz, J.3    Camus, M.4    Tournaye, H.5    Van Steirteghem, A.C.6    Devroey, P.7
  • 46
    • 84913594238 scopus 로고    scopus 로고
    • CAR expression in human embryos and hESC illustrates its role in pluripotency and tight junctions
    • Krivega MV, Geens M, Van de Velde H. CAR expression in human embryos and hESC illustrates its role in pluripotency and tight junctions. Reproduction 2014;148:531-544.
    • (2014) Reproduction , vol.148 , pp. 531-544
    • Krivega, M.V.1    Geens, M.2    Van de Velde, H.3
  • 47
    • 84856689924 scopus 로고    scopus 로고
    • The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos
    • Kuijk EW, van Tol LT, Van de Velde H, Wubbolts R,Welling M, Geijsen N, Roelen BA. The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos. Development 2012;139:871-882.
    • (2012) Development , vol.139 , pp. 871-882
    • Kuijk, E.W.1    van Tol, L.T.2    Van de Velde, H.3    Wubbolts, R.4    Welling, M.5    Geijsen, N.6    Roelen, B.A.7
  • 49
    • 79959999016 scopus 로고    scopus 로고
    • Differential requirement for the dual functions of b-catenin in embryonic stem cell self-renewal and germ layer formation
    • Lyashenko N, Winter M, Migliorini D, Biechele T, Moon RT, Hartmann C. Differential requirement for the dual functions of b-catenin in embryonic stem cell self-renewal and germ layer formation. Nat Cell Biol 2011; 13:753-761.
    • (2011) Nat Cell Biol , vol.13 , pp. 753-761
    • Lyashenko, N.1    Winter, M.2    Migliorini, D.3    Biechele, T.4    Moon, R.T.5    Hartmann, C.6
  • 51
    • 84865299701 scopus 로고    scopus 로고
    • b-Catenin/ Wnt signaling controls progenitor fate in the developing and regenerating zebrafish retina
    • Meyers JR, Hu L, Moses A, Kaboli K, Papandrea A, Raymond PA. b-Catenin/ Wnt signaling controls progenitor fate in the developing and regenerating zebrafish retina. Neural Dev 2012;7:30.
    • (2012) Neural Dev , vol.7 , pp. 30
    • Meyers, J.R.1    Hu, L.2    Moses, A.3    Kaboli, K.4    Papandrea, A.5    Raymond, P.A.6
  • 52
    • 84873524509 scopus 로고    scopus 로고
    • Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse
    • Niakan KK, Eggan K. Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse. Dev Biol 2013;375:54-64.
    • (2013) Dev Biol , vol.375 , pp. 54-64
    • Niakan, K.K.1    Eggan, K.2
  • 55
    • 33749645068 scopus 로고    scopus 로고
    • Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
    • Pereira L, Yi F, Merrill BJ. Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal. Mol Cell Biol 2006; 26:7479-7491.
    • (2006) Mol Cell Biol , vol.26 , pp. 7479-7491
    • Pereira, L.1    Yi, F.2    Merrill, B.J.3
  • 56
    • 0038746598 scopus 로고    scopus 로고
    • An open, randomized single-centre study to compare the efficacy and convenience of follitropin beta administered by a pen device with follitropin alpha administered by a conventional syringe in women undergoing ovarian stimulation for IVF/ ICSI
    • Platteau P, Laurent E, Albano C, Osmanagaoglu K, Vernaeve V, Tournaye H, Camus M, Van Steirteghem A, Devroey P. An open, randomized single-centre study to compare the efficacy and convenience of follitropin beta administered by a pen device with follitropin alpha administered by a conventional syringe in women undergoing ovarian stimulation for IVF/ ICSI. Hum Reprod 2003;18:1200-1204.
    • (2003) Hum Reprod , vol.18 , pp. 1200-1204
    • Platteau, P.1    Laurent, E.2    Albano, C.3    Osmanagaoglu, K.4    Vernaeve, V.5    Tournaye, H.6    Camus, M.7    Van Steirteghem, A.8    Devroey, P.9
  • 57
    • 80052839741 scopus 로고    scopus 로고
    • Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells
    • QiuW, Chen L, Kassem M. Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells. Biochem Biophys Res Commun 2011;413:98-104.
    • (2011) Biochem Biophys Res Commun , vol.413 , pp. 98-104
    • Qiu, W.1    Chen, L.2    Kassem, M.3
  • 58
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro
    • Reubinoff BE, PeraMF, FongCY,Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol 2000;18:399-404.
    • (2000) Nat Biotechnol , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 60
    • 67650076196 scopus 로고    scopus 로고
    • Wnt3a regulates proliferation and migration of HUVEC via canonical and non-canonical Wnt signaling pathways
    • Samarzija I, Sini P, Schlange T, Macdonald G, Hynes NE. Wnt3a regulates proliferation and migration of HUVEC via canonical and non-canonical Wnt signaling pathways. Biochem Biophys Res Commun 2009; 386:449-454.
    • (2009) Biochem Biophys Res Commun , vol.386 , pp. 449-454
    • Samarzija, I.1    Sini, P.2    Schlange, T.3    Macdonald, G.4    Hynes, N.E.5
  • 61
    • 77950223473 scopus 로고    scopus 로고
    • Mechanisms of trophectoderm fate specification in preimplantation mouse development
    • Sasaki H. Mechanisms of trophectoderm fate specification in preimplantation mouse development. Dev Growth Differ 2010;52:263-273.
    • (2010) Dev Growth Differ , vol.52 , pp. 263-273
    • Sasaki, H.1
  • 62
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004;10:55-63.
    • (2004) Nat Med , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 63
    • 73549109609 scopus 로고    scopus 로고
    • Making heads from tails: development of a reversed anterior-posterior axis during budding in an acoel
    • Sikes JM, Bely AE. Making heads from tails: development of a reversed anterior-posterior axis during budding in an acoel. Dev Biol 2010; 338:86-97.
    • (2010) Dev Biol , vol.338 , pp. 86-97
    • Sikes, J.M.1    Bely, A.E.2
  • 64
    • 84863241921 scopus 로고    scopus 로고
    • Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation
    • SinghAM,Reynolds D, CliffT, Ohtsuka S, Mattheyses AL, SunY, Menendez L, Kulik M, Dalton S. Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation. Cell Stem Cell 2012;10:312-326.
    • (2012) Cell Stem Cell , vol.10 , pp. 312-326
    • Singh, A.M.1    Reynolds, D.2    Cliff, T.3    Ohtsuka, S.4    Mattheyses, A.L.5    Sun, Y.6    Menendez, L.7    Kulik, M.8    Dalton, S.9
  • 65
    • 80053063127 scopus 로고    scopus 로고
    • Maintaining embryonic stem cell pluripotency with Wnt signaling
    • Sokol SY. Maintaining embryonic stem cell pluripotency with Wnt signaling. Development 2011;138:4341-4350.
    • (2011) Development , vol.138 , pp. 4341-4350
    • Sokol, S.Y.1
  • 66
    • 84866885394 scopus 로고    scopus 로고
    • FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells
    • Sui L, Mfopou JK, Geens M, Sermon K, Bouwens L. FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells. Biochem Biophys Res Commun 2012;426:380-385.
    • (2012) Biochem Biophys Res Commun , vol.426 , pp. 380-385
    • Sui, L.1    Mfopou, J.K.2    Geens, M.3    Sermon, K.4    Bouwens, L.5
  • 67
    • 53349091628 scopus 로고    scopus 로고
    • Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling
    • Sumi T, Tsuneyoshi N, Nakatsuji N, Suemori H. Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling. Development 2008;135:2969-2979.
    • (2008) Development , vol.135 , pp. 2969-2979
    • Sumi, T.1    Tsuneyoshi, N.2    Nakatsuji, N.3    Suemori, H.4
  • 68
    • 84857132318 scopus 로고    scopus 로고
    • Factors regulating pluripotency and differentiation in early mammalian embryos and embryo-derived stem cells
    • Suwinska A, Ciemerych MA. Factors regulating pluripotency and differentiation in early mammalian embryos and embryo-derived stem cells. Vitam Horm 2011;87:1-37.
    • (2011) Vitam Horm , vol.87 , pp. 1-37
    • Suwinska, A.1    Ciemerych, M.A.2
  • 70
    • 54949102409 scopus 로고    scopus 로고
    • Wnt signaling mediates self-organization and axis formation in embryoid bodies
    • ten Berge D, KooleW, Fuerer C, Fish M, Eroglu E, Nusse R. Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 2008;3:508-518.
    • (2008) Cell Stem Cell , vol.3 , pp. 508-518
    • ten Berge, D.1    Koole, W.2    Fuerer, C.3    Fish, M.4    Eroglu, E.5    Nusse, R.6
  • 77
    • 0030732670 scopus 로고    scopus 로고
    • Effects of different hyaluronidase concentrations and mechanical procedures for cumulus cell removal on the outcome of intracytoplasmic sperm injection
    • Van de Velde H, Nagy ZP, Joris H, De Vos A, Van Steirteghem AC. Effects of different hyaluronidase concentrations and mechanical procedures for cumulus cell removal on the outcome of intracytoplasmic sperm injection. Hum Reprod 1997;12:2246-2250.
    • (1997) Hum Reprod , vol.12 , pp. 2246-2250
    • Van de Velde, H.1    Nagy, Z.P.2    Joris, H.3    De Vos, A.4    Van Steirteghem, A.C.5
  • 78
    • 84872457949 scopus 로고    scopus 로고
    • The combination of inhibitors of FGF/MEK/Erk and GSK3b signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation
    • Van der Jeught M, O'Leary T, Ghimire S, Lierman S, Duggal G, Versieren K, Deforce D, Chuva de Sousa Lopes S, Heindryckx B, De Sutter P. The combination of inhibitors of FGF/MEK/Erk and GSK3b signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation. Stem Cells Dev 2013;22:296-306.
    • (2013) Stem Cells Dev , vol.22 , pp. 296-306
    • Van der Jeught, M.1    O'Leary, T.2    Ghimire, S.3    Lierman, S.4    Duggal, G.5    Versieren, K.6    Deforce, D.7    Chuva de Sousa Lopes, S.8    Heindryckx, B.9    De Sutter, P.10
  • 79
  • 80
    • 84885943260 scopus 로고    scopus 로고
    • Influence of cell loss after vitrification or slow-freezing on further in vitro development and implantation of human Day 3 embryos
    • Van Landuyt L, Van de Velde H, De Vos A, Haentjens P, Blockeel C, Tournaye H, Verheyen G. Influence of cell loss after vitrification or slow-freezing on further in vitro development and implantation of human Day 3 embryos. Hum Reprod 2013;28:2943-2949.
    • (2013) Hum Reprod , vol.28 , pp. 2943-2949
    • Van Landuyt, L.1    Van de Velde, H.2    De Vos, A.3    Haentjens, P.4    Blockeel, C.5    Tournaye, H.6    Verheyen, G.7
  • 82
    • 84857793584 scopus 로고    scopus 로고
    • WNTing embryonic stem cells
    • Wray J, Hartmann C. WNTing embryonic stem cells. Trends Cell Biol 2012; 22:159-168.
    • (2012) Trends Cell Biol , vol.22 , pp. 159-168
    • Wray, J.1    Hartmann, C.2
  • 83
    • 79959950773 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    • Wray J, Kalkan T, Gomez-Lopez S, Eckardt D, Cook A, Kemler R, Smith A. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat Cell Biol 2011;13:838-845.
    • (2011) Nat Cell Biol , vol.13 , pp. 838-845
    • Wray, J.1    Kalkan, T.2    Gomez-Lopez, S.3    Eckardt, D.4    Cook, A.5    Kemler, R.6    Smith, A.7
  • 84
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L, Yuan X, Sharkis SJ. Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 2006;24:1476-1486.
    • (2006) Stem Cells , vol.24 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 85
    • 40949135002 scopus 로고    scopus 로고
    • Inactivation of nuclear Wnt-beta-catenin signaling limits blastocyst competency for implantation
    • Xie H, Tranguch S, Jia X, Zhang H, Das SK, Dey SK, Kuo CJ, Wang H. Inactivation of nuclear Wnt-beta-catenin signaling limits blastocyst competency for implantation. Development 2008;135:717-727.
    • (2008) Development , vol.135 , pp. 717-727
    • Xie, H.1    Tranguch, S.2    Jia, X.3    Zhang, H.4    Das, S.K.5    Dey, S.K.6    Kuo, C.J.7    Wang, H.8
  • 88
    • 84855698586 scopus 로고    scopus 로고
    • Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins
    • Yadav VR, Prasad S, Aggarwal BB. Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins. Br J Pharmacol 2012; 165:741-753.
    • (2012) Br J Pharmacol , vol.165 , pp. 741-753
    • Yadav, V.R.1    Prasad, S.2    Aggarwal, B.B.3


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