Tracking the progression of the human inner cell mass during embryonic stem cell derivation

Nature Biotechnology

Volumn 30, Issue 3, 2012, Pages 278-282

  O'Leary, Thomas ^a   Heindryckx, Björn ^a   Lierman, Sylvie ^a   Van Bruggen, David ^b   Goeman, Jelle J ^b   Vandewoestyne, Mado ^c   Deforce, Dieter ^c   De Sousa Lopes, Susana M Chuva ^b   De Sutter, Petra ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; CRYOPRESERVED; DEVELOPMENTAL STAGE; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; HUMAN CELLS; IN-VITRO; IN-VIVO; INNER CELL MASS; MOLECULAR CHANGES; MOUSE EMBRYONIC STEM CELLS; PLURIPOTENT;

CELL GROWTH; MAMMALS; STEM CELLS;

CYTOLOGY;

ANIMAL CELL; ARTICLE; DEVELOPMENTAL STAGE; ECTODERM; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INNER CELL MASS; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; X CHROMOSOME INACTIVATION;

ANIMALS; BLASTOCYST INNER CELL MASS; EMBRYONIC STEM CELLS; FEMALE; HUMANS; MICE; OCTAMER TRANSCRIPTION FACTOR-3; REPRESSOR PROTEINS; RNA-BINDING PROTEINS; SOXB1 TRANSCRIPTION FACTORS; X CHROMOSOME INACTIVATION;

EID: 84857991080     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.2135     Document Type: Article

References (41)

1. Han, D.W. et al. Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell 143, 617-627 (2010).
2. Hayashi, K., Lopes, S.M., Tang, F. & Surani, M.A. Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3, 391-401 (2008).
3. Kuijk, E.W., Chuva de Sousa Lopes, S.M., Geijsen, N., Macklon, N. & Roeien, B.A. The different shades of mammalian pluripotent stem cells. Hum. Reprod. Update 17, 254-271 (2011).
4. Nichols, J. & Smith, A. Naive and primed pluripotent states. Cell Stem Cell 4, 487-492 (2009).
5. Nichols, J. & Smith, A. The origin and identity of embryonic stem cells. Development 138, 3-8 (2011).
6. Hanna, J. et al. Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell 4, 513-524 (2009).
7. Chen, A.E. et al. Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. Cell Stem Cell 4, 103-106 (2009).
8. Brons, I.G. et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448, 191-195 (2007).
9. Tesar, P.J. et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196-199 (2007).
10. Tang, F., Lao, K. & Surani, M.A. Development and applications of single-cell transcriptome analysis. Nat. Methods 8, S6-S11 (2011).
11. Najm, F.J. et al. Isolation of epiblast stem cells from preimplantation mouse embryos. Cell Stem Cell 8, 318-325 (2011).
12. Reijo Pera, R.A. et al. Gene expression profiles of human inner cell mass cells and embryonic stem cells. Differentiation 78, 18-23 (2009).
13. O'Leary, T. et al. The influence of early embryo traits on human embryonic stem cell derivation efficiency. Stem Cells Dev. 785-793 (2011).
14. Guo, G. et al. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev. Cell 18, 675-685 (2010).
15. Rathjen, J. et al. Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors. J. Cell Sci. 112, 601-612 (1999).
16. Hanna, L.A., Foreman, R.K., Tarasenko, I.A., Kessler, D.S. & Labosky, P.A. Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 16, 2650-2661 (2002).
17. Tanaka, S.S. & Matsui, Y. Developmentally regulated expression of mil-1 and mil-2, mouse interferon-induced transmembrane protein like genes, during formation and differentiation of primordial germ cells. Mech. Dev. 119 (suppl. 1), S261-S267 (2002).
18. Pelton, T.A., Sharma, S., Schulz, T.C., Rathjen, J. & Rathjen, P.D. Transient pluripotent cell populations during primitive ectoderm formation: correlation of in vivo and in vitro pluripotent cell development. J. Cell Sci. 115, 329-339 (2002).
19. Silva, S.S., Rowntree, R.K., Mekhoubad, S. & Lee, J.T. X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells. Proc. Natl. Acad. Sci. USA 105, 4820-4825 (2008).
20. Lengner, C.J. et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141, 872-883 (2010).
21. Chuva de Sousa Lopes, S.M. et al. X chromosome activity in mouse XX primordial germ cells. PLoS Genet. 4, e30 (2008).
22. Chazaud, C., Yamanaka, Y., Pawson, T. & Rossant, J. Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev. Cell 10, 615-624 (2006).
23. Vallier, L. et al. Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. Development 136, 1339-1349 (2009).
24. Vallier, L. et al. Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways. PLoS ONE 4, e6082 (2009).
25. James, D., Levine, A.J., Besser, D. & Hemmati-Brivanlou, A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132, 1273-1282 (2005).
26. Tam, P.P.L. & Loebel, D.A.F. Gene function in mouse embryogenesis: get set for gastrulation. Nat. Rev. Genet. 8, 368-381 (2007).
27. Dravid, G. et al. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells 23, 1489-1501 (2005).
28. Sumi, T., Tsuneyoshi, N., Nakatsuji, N. & Suemori, H. Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling. Development 135, 2969-2979 (2008).
29. Hough, S.R., Laslett, A.L., Grimmond, S.B., Kolle, G. & Pera, M.F. A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells. PLoS ONE 4, e7708 (2009).
30. Chambers, I. et al. Nanog safeguards pluripotency and mediates germline development. Nature 450, 1230-1234 (2007).
31. Carson, D.D. et al. Embryo implantation. Dev. Biol. 223, 217-237 (2000).
32. Chuva de Sousa Lopes, S.M. & Roelen, B.A. On the formation of germ cells: The good, the bad and the ugly. Differentiation 79, 131-140 (2010).
33. Chuva de Sousa Lopes, S.M. & Roelen, B.A. An overview on the diversity of cellular organelles during the germ cell cycle. Histol. Histopathol. 25, 267-276 (2010).
34. Stephenson, E.L., Braude, P.R. & Mason, C. International community consensus standard for reporting derivation of human embryonic stem cell lines. Regen. Med. 2, 349-362 (2007).
35. Solter, D. & Knowles, B.B. Immunosurgery of mouse blastocyst. Proc. Natl. Acad. Sci. USA 72, 5099-5102 (1975).
36. Strom, S. et al. Mechanical isolation of the inner cell mass is effective in derivation of new human embryonic stem cell lines. Hum. Reprod. 22, 3051-3058 (2007).
37. Chuva de Sousa Lopes, S.M. et al. BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev. 18, 1838-1849 (2004).
38. Vandewoestyne, M. et al. Polar body mutation load analysis in a patient with A3243G tRNALeu(UUR) point mutation. Mitochondrion 11, 626-629 (2011).
39. Krenke, B.E. et al. Validation of a 16-locus fluorescent multiplex system. J. Forensic Sci. 47, 773-785 (2002).
40. Mukaida, T. et al. Vitrification of human blastocysts using cryoloops: clinical outcome of 223 cycles. Hum. Reprod. 18, 384-391 (2003).
41. Holm, S. A simple sequentially rejective multiple test procedure. Scand. J. Stat. 6, 65-70 (1979).