The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4-and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation

Stem Cells and Development

Volumn 22, Issue 2, 2013, Pages 296-306

  Van Der Jeught, Margot ^a   O'Leary, Thomas ^a   Ghimire, Sabitri ^a   Lierman, Sylvie ^a   Duggal, Galbha ^a   Versieren, Karen ^a   Deforce, Dieter ^b   Chuva De Sousa Lopes, Susana ^c   Heindryckx, Björn ^a   De Sutter, Petra ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHIR 99021; FIBROBLAST GROWTH FACTOR; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ARTICLE; BLASTOCYST; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; EMBRYONIC STEM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; INNER CELL MASS; NIDATION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL;

BENZAMIDES; BLASTOCYST INNER CELL MASS; CELL COUNT; CELL CULTURE TECHNIQUES; CELL LINEAGE; DIPHENYLAMINE; EMBRYO CULTURE TECHNIQUES; EMBRYO IMPLANTATION; EMBRYONIC STEM CELLS; GATA6 TRANSCRIPTION FACTOR; GLYCOGEN SYNTHASE KINASE 3; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; OCTAMER TRANSCRIPTION FACTOR-3; PYRIDINES; PYRIMIDINES; SIGNAL TRANSDUCTION; TIME FACTORS;

MUS;

EID: 84872457949     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0256     Document Type: Article

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