Pellino-1 positively regulates Toll-like receptor (TLR) 2 and TLR4 signaling and is suppressed upon induction of endotoxin tolerance

Journal of Biological Chemistry

Volumn 290, Issue 31, 2015, Pages 19218-19232

  Murphy, Michael ^a   Xiong, Yanbao ^b   Pattabiraman, Goutham ^a   Qiu, Fu ^b,c   Medvedev, Andrei E ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; BACTERIA; CHEMICAL ACTIVATION; ENZYMES; ESCHERICHIA COLI; MACROPHAGES; PROTEINS;

ANTI-INFLAMMATORIES; IL-1 RECEPTOR-ASSOCIATED KINASE; MYELOID DIFFERENTIATION; NUCLEAR FACTOR KAPPAB; PRO-INFLAMMATORY CYTOKINES; PROTEIN EXPRESSIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTORS;

SIGNALING;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 8; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PELLINO 1; PHOSPHOTRANSFERASE; TANK BINDING KINASE 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; NUCLEAR PROTEIN; PELI1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TBK1 PROTEIN, HUMAN; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOTOXIN TOLERANCE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INTERLEUKIN 8 GENE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; UBIQUITINATION; ANIMAL; C57BL MOUSE; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; MONOCYTE; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ANIMALS; HEK293 CELLS; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIPOPOLYSACCHARIDES; MAP KINASE KINASE KINASES; MICE, INBRED C57BL; MONOCYTES; NF-KAPPA B; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TRANSCRIPTIONAL ACTIVATION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84940704133     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.640128     Document Type: Article

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